Human White Matter Disease

Room 611 - 612         11:00 - 13:00                 Chairs: Micheal D. Phillips and Gioacchino Tedeschi

Time

Prog #

 
11:00 444.

T1 Tissue Specific Imaging in Multiple Sclerosis: Sensitivity and Specificity Issues

Vasiliki N. Ikonomidou1, Francesca Bagnato1, Peter van Gelderen1, Marco Riva1, Fernanda Tovar-Moll1,

Jacco A. de Zwart1, Silvina G. Horovitz1, Joan Ohayon1, Henry F. McFarland1, Jeff H. Duyn1

1National Institutes of Health, Bethesda, Maryland, USA
11:12 445.

Voxelwise MT Analysis Shows Less Pronounced Brain Tissue Damage in Benign MS Than in Early Relapsing MS

Marco Battaglini1, Maria Laura Stromillo1, Maria Laura Bartolozzi2, Valentina Zipoli3, Benedetta Goretti3,

Leonello Guidi2, Emilio Portaccio3, Antonio Giorgio1, Antonio Federico1, Maria Pia Amato3, Nicola De Stefano1

1University of Siena, Siena, Italy; 2Empoli Hospital, Empoli, Italy; 3University of Florence, Florence, Italy

11:24 446.

Long-T2 Imaging: Evidence of a New Water Reservoir in Multiple Sclerosis

Cornelia Laule1, Irene M. Vavasour1, Anthony L. Traboulsee1, David K.B. Li1, Alex L. MacKay1

1University of British Columbia, Vancouver, BC, Canada
11:36 447.

MRI of Post Mortem Multiple Sclerosis Brain: Quantifying the Effects of Formalin Fixation

Klaus DG Schmierer1, Daniel J. Tozer1, Claudia AM Wheeler-Kingshott1, Phil A. Boulby1, Harold G. Parkes1,

Tarek A. Yousry1, Paul S. Tofts1, David H. Miller1

1Institute of Neurology, UCL, London, England, UK
11:48 448.

De- Or Hypomyelination in Myelinopathia Centralis Diffusa/Leukoencephalopathy with Vanishing White Matter? Insights

from Localized Proton MRS

Steffi F. Dreha-Kulaczewski1, Peter Dechent1, Jürgen Finsterbusch2, Knut Brockmann1, Bernd Wilken3, Jutta Gärtner1, Jens Frahm2,

Folker Hanefeld1

1Georg-August-University, Goettingen, Lower Saxony, Germany; 2Biomedizinische Forschungs GmbH am MPI für biophysikalische Chemie, Goettingen, Lower Saxony, Germany; 3Clinic of Pediatric Neurology, Kassel, Lower Saxony, Germany
12:00 449.

Diffusion Tensor Imaging Study of Pelizaeus-Merzbacher Disease

Jeremy Laukka1, Malek Makki2, James Garbern1

1Wayne State University, Detroit, Michigan, USA; 2Children's Hospital of Michigan, Detroit, Michigan, USA
12:12 450.

Microembolization is a Likely Contributing Factor to Leukoaraiosis in Patients with Symptomatic Carotid Artery Disease

Nishath Altaf1, 2, Paul S. Morgan1, Lucy Daniels1, John R. Gladman1, Shane T. MacSweeney2, Tim Jaspan1,

Alan R. Moody3, Dorothee P. Auer1

1University of Nottingham, Nottingham, Nottinghamshire, UK; 2Queen's Medical Centre, Nottingham, Nottinghamshire, UK;

3Sunnybrook and Women's College Health Sciences Centre, Ontario, Canada

12:24 451.

Detection of Change in CNS Involvement in NPSLE with Magnetization Transfer Imaging

Bart Jeroen Emmer1, S C. Steens1, G M. Steup-Beekman1, J van der Grond1, F Admiraal-Behloul1, H Olofsen1,

G P. Bosma1, W J. Ouwendijk1, T W. Huizinga1, M A. van Buchem1

1Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands
12:36 452.

Validation of a White-Matter Specific Dual MR/optical Contrast Agent for High-Resolution Imaging

Megan L. Blackwell1, 2, Christian T. Farrar1, Bruce R. Rosen1, 2

1Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA; 2Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
12:48 453.

Diffusion Measurement of Human Optic Nerve Using Fat Suppressed Diffusion Turbo FLASH Sequence

Junqian G. Xu1, Sheng-Kwei Song1

1Washington University in St. Louis, St. Louis, Missouri, USA