TRADITIONAL POSTERS

MRI in Animal Models Other Than Stroke

                  930.      MRI Microscopy of Alzheimer Plaques in APP751 Transgenic Mice: Effect of TE and Spatial Resolution
                                on Plaque Detectability

Amnon Bar-Shir¹, Yoram Cohen¹

¹Tel-Aviv University, Tel-Aviv, Israel

                  931.      Screening Mutagenic Mice with Ventricular Mutation: A Longitudinal Study

Yu-Ying Tung¹, Ching-Po Lin², Chen Chang¹

¹Functional and Micro-MRI Center, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; ²Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan

                  932.      Evaluation of Neurodegeneration in a Mouse Model of INCL by MRI and Spectroscopic Analyses

Alison Heffer¹, Jeeva P. Munasinghe¹, Zhongjian Zhang¹, Sandra L. Hofmann², Alan P. Koretsky¹, Anil Mukherjee¹

¹National Institutes of Health, Bethesda, Maryland, USA; ²University of Texas, Dallas, Texas, USA

                  933.      Longitudinal Study of the Development of Beta-Amyloid Plaque Burden in a Transgenic Mouse
                                Model of Alzheimer’s Disease, Using In Vivo Magnetic Resonance Imaging

Niels Braakman¹, Jörg Matysik¹, Sjoerd G. van Duinen², Fons Verbeek¹, Reinhard Schliebs³, Huub J. M. de Groot¹, Alia Alia¹

¹Leiden University, Leiden, Netherlands; ²Leiden University Medical Center, Leiden, Netherlands; ³University of Leipzig, Leipzig, Germany

                  934.      In Vivo Quantification of Neuronal Degeneration in the G93A-SOD1 Transgenic Mouse Model
                                of ALS by T₂ Mapping

Heiko G. Niessen¹, Frank Angenstein, ¹², Kerstin Sander², Hans-Jochen Heinze¹, Henning Scheich², Stefan Vielhaber¹

¹University of Magdeburg, Magdeburg, LSA, Germany; ²Leibniz Institute for Neurobiology, Magdeburg, LSA, Germany

                  935.      Development of a VBM Protocol for Assessing Regional Gray and White Matter Brain Changes in a
                                Canine Model of Aging

P D. Tapp¹, Kevin Head¹, Elizabeth Head¹, Nortan W. Milgram², Bruce A. Muggenburg³, Orhan Nalcioglu¹,

Min-Ying Su¹

¹University of California, Irvine, California, USA; ²University of Toronto, Toronto, Ontario, Canada; ³Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA

                  936.      Comparison of MRI with Histopathology in T-Cell Clone Mediated Mouse EAE

Susann Boretius¹, Steffan Nessler², Christine Stadelmann³, Takashi Watanabe¹, Jens Frahm¹, Thomas Michaelis¹

¹Max-Planck-Institut fuer biophysikalische Chemie, Goettingen, Germany; ²Heinrich-Heine-University, Duesseldorf, Germany; ³Gerog-August-University, Goettingen, Germany

                  937.      Axonal Injury is Detected by Postmortem DTI Before Fixation (But Not After)

Shu-Wei Sun¹, Hsiao-Fang Liang¹, Sheng-Kwei Song¹

¹Washington University, St. Louis, Missouri, USA

                  938.      Temporal Evaluations of the EAE-Induced Pathologies in the Grey Matter of Chronic Relapsing EAE

Anil Zechariah¹, Yi-Hua Hsu¹, Chen Chang¹

¹Functional and Micro-MRI Center, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

                  939.      Sequential Cerebral MRI of Listeria Brain Stem Encephalitis in Mice - Visualization of Sub-Clinical Lesions

Christian Brekken¹, Ellen-Ann Antal², Pål Erik Goa¹, Tina Bugge Pedersen¹, Else Løberg², Kjetil Klaveness Melby², Jan Mæhlen², Olav Haraldseth¹

¹Norwegian University of Science and Technology, FUGE MIC, Trondheim, Norway; ²University of Oslo, Ullevaal University Hospital, Oslo, Norway

                  940.      Increased Dietary Lysine and Associated Age Dependent Bilateral Striatal Damage in
                                Glutaryl-CoA Dehydrogenase Deficient Mice

William Zinnanti¹, Jelena Lazovic², Keith Cheng¹, Michael B. Smith¹

¹Penn State College of Medicine, Hershey, Pennsylvania, USA; ²California Institute of Technology, Pasadena, California, USA

                  941.      MRI Changes in CBF, Diffusion and T2 After Seizures Induced by GluR5 Agonist Infusion in Rat Before 180 Mins

Jeeva P. Munasinghe¹, Madhumitha Banerjee¹, Maria Acosta¹, Alison Heffer¹, S-I Yamaguchi¹, Michael A. Rogawski¹, Afonso C. Silva¹, Alan P. Koretsky¹, William H. Theodore¹

¹National Institutes of Health, Bethesda, Maryland, USA

                  942.      High-Resolution MRI of NPC Mice Shows Neurological Changes Prior to Onset of Disease Symptoms

Chad Hicks¹, Silvia Lope-Piedrafita¹, Elizabeth Chaitkin¹, Emelia Allee-Jumbo¹, Lan Lin², Robert Erickson¹,

Kewei Chen³, Gene Alexander², Theodore Trouard¹

¹University of Arizona, Tucson, Arizona, USA; ²Arizona State University, Tempe, Arizona, USA; ³PET Center, Phoenix, Arizona, USA

                  943.      The Impact of Hydrocephalus in Experimental Meningitis

Christian Brandt¹, Helle J. Simonsen², Lise Vejby Søgaard², Olaf B. Paulson², Ian J. Rowland²

¹Statens Serum Institut, Copenhagen, Denmark; ²Copenhagen University Hospital, Hvidovre, Denmark

                  944.      Intranasal Insulin Delivery is Protective Against Diabetes Mellitus-Related Brain Atrophy and
                                White Matter Abnormalities in Experimental Diabetes Mellitus

Cory Toth¹, Ursula I. Tuor¹, Douglas Zochodne¹

¹University of Calgary, Calgary, Alberta, Canada

                  945.      In Vivo Study of the Development of Hippocampal Subregions by High-Resolution Diffusion Weighted Imaging

Hsiao-Wen Chen¹, ², Yi-Hua Hsu², Wei-C. Chu¹, Chen Chang²

¹Institute of Biomedical Engineering, National Yang-Ming University, Taipei, Taiwan; ²Functional and Micro-MRI Center, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

                  946.      MRI Assessment of Aß-Iron Complex in PS/APP Mouse Brain

Maria F. Falangola¹, ², Sang-Pil Lee³, Jens H. Jensen¹, Hanzhang Lu¹, Ralph A. Nixon², Karen Duff²,

Joseph A. Helpern¹, ²

¹New York University School of Medicine, New York, New York, USA; ²Nathan Kline Institute, Orangeburg, New York, USA; ³University of Kansas Medical Center, Kansas City, Kansas, USA

Animal Brain MRS 13C, 17OZ, 7Li, 15N

                  947.      The Anaplerotic Metabolic Flux Through Pyruvate Carboxylase is a Prerequisite for Ammonia
                                Detoxification in Acute and Chronic Liver Failure

Claudia Zwingmann¹, ², Roger Butterworth¹, Dieter Leibfritz²

¹Hospital Saint-Luc, Montreal, Quebec, Canada; ²University of Bremen, Bremen, Germany

                  948.      Glucose Metabolism in Animals with a Traumatic Brain Injury: A 13C NMR Study

Brenda L. Bartnik¹, ², David A. Hovda², Richard L. Sutton²

¹Loma Linda University, Loma Linda, California, USA; ²University of California Los Angeles, Los Angeles, California, USA

                  949.      Neuronal-Glial Glucose Oxidation and Glutamatergic-GABAergic Function Revealed by ¹³C MRS Studies

Fahmeed Hyder¹, Anant Bahadur Patel¹, Albert Gjedde², Douglas L. Rothman¹, Kevin L. Behar¹, Robert G. Shulman¹

¹Magnetic Resonance Research Center, Yale University, New Haven, Connecticut, USA; ²Aarhus University, Aarhus, Denmark

                  950.      Investigation of  the Role of GABA Reuptake in GABAergic Neurotransmission

Anant Bahadur Patel¹, Robin A. de Graaf¹, Douglas L. Rothman¹, Kevin L. Behar¹

¹Magnetic Resonance Research Center, Yale University, New Haven, Connecticut, USA

                  951.      Comparison of Amino Acid Turnover Rates in Cortex and Isolated Nerve Terminals of the Anesthetized Rat

Anant Bahadur Patel¹, James CK Lai², Golam MI Chowdhury¹, Douglas L. Rothman¹, Kevin L. Behar¹

¹Magnetic Resonance Research Center, Yale University, New Haven, Connecticut, USA; ²Idaho State University, Pocatello, Idaho, USA

                  952.      Evaluation of the Simplified Method for Mapping Cerebral Metabolic Rate of Oxygen Based
                                on ¹⁷O NMR Approach

Nanyin Zhang¹, Xiao-Hong Zhu¹, Wei Chen¹

¹University of Minnesota, Minneapolis, Minnesota, USA

                  953.      Estimating Intracellular Lithium in Brain In Vivo by Lithium-7 MRS

Richard A. Komoroski¹, John M. Pearce²

¹University of Cincinnati, Cincinnati, Ohio, USA; ²University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

                  954.      Glial Glutamine Release and Neuronal Reuptake by SAT1 Studied In Vivo by N-15 NMR and Microdialysis

Keiko Kanamori¹, Brian D. Ross¹

¹Huntington Medical Research Institutes, Pasadena, California, USA


 

Brain: Different Types of Relaxation and Angiography

                  955.      Chromium-Enhanced MRI of Myelinated Structures in Mouse Brain In Vivo

Takashi Watanabe¹, Roland Tammer¹, Susann Boretius¹, Jens Frahm¹, Thomas Michaelis¹

¹Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany

                  956.      Regional T1 Relaxation Time and Tissue Content Changes of Hippocampus in Bipolar Disorder

Wen-Jang Chu¹, Stephen M. Strakowski¹, Hoby P. Hetherington², Mellissa P. DelBello¹, Cal M. Adler¹, Jing-Huei Lee¹

¹Univ. of Cincinnati, Cincinnati, Ohio, USA; ²Albert Einstein College of Medicine, Bronx, New York, USA

                  957.      Establishment of an In Vivo Iron and R₂* Calibration Curve

Mark David Meadowcroft¹, James R. Connor¹, Jian-li Wang¹, Xiaoyu Sun¹, Michael B. Smith¹, Qing X. Yang¹

¹Pennsylvania State University - College of Medicine, Hershey, Pennsylvania, USA

                  958.      3D-Relaxometry - Quantitative T1 and T2 Brain Mapping at 3T

Burkhard Mädler¹, ², Trudy Harris³, Alex L. MacKay²

¹UBC Hospital, Vancouver, BC, Canada; ²University of British Columbia, Vancouver, BC, Canada; ³Vancouver Coastal Health, Vancouver, BC, Canada

                  959.      Normal Regional T₁ and T₂ Relaxation Times of the Brain at 3T

Christabel E.C. Lee¹, Eva H. Baker¹, David M. Thomasson¹

¹NIH, Bethesda, Maryland, USA

                  960.      Long T₂ Imaging: Evidence of a New Water Reservoir in Phenylketonuria

Cornelia Laule¹, Sumia A. Tahir¹, Sandra M. Sirrs¹, Elana E. Brief², Carole Bishop¹, David KB Li¹, Alex L. MacKay¹

¹University of British Columbia, Vancouver, BC, Canada; ²Simon Fraser University, Burnaby, BC, Canada

                  961.      Multicomponent T2 Analysis of Rat Brain and Spinal Cord at 9.4 T

Cheryl Rae McCreary¹, Debbie Anne Kelly¹, Boguslaw Tomanek², Tadeusz Foniok², Dave Kirk¹, Jeff Frank Dunn¹

¹University of Calgary, Calgary, AB, Canada; ²National Research Council, Calgary, AB, Canada

                  962.      Positive Contrast Susceptibility Weighted Imaging of Physiologic Calcification in Humans

John A. Butman¹, Wei Liu², Tobias Schaeffter³

¹National Institutes of Health, Bethesda, Maryland, USA; ²Philips Research North America, Briarcliff Manor, New York, USA; ³Philips Research Germany, Hamburg, Germany

                  963.      A Novel Technique to Study Mouse Cerebrovasculature Using MR Guided Micro-CT

Brige Paul Chugh¹, ², Lisa X. Yu¹, R. Mark Henkelman¹, John G. Sled¹

¹Mouse Imaging Centre (MICe), Toronto, Ontario, Canada; ²University of Toronto, Toronto, Ontario, Canada

                  964.      USPIO Enhanced Susceptibility Weighted Magnetic Resonance Imaging of the Mouse Brain Vascular Architecture

Bob Hamans¹, Markus Barth², William Leenders¹, Arend Heerschap¹

¹Radboud University Medical Centre, Nijmegen, Netherlands; ²Radboud University, Nijmegen, Netherlands

                  965.      Cerebral MR Angiography in Mice with a New Blood Pool Agent (P792)

Nadine El Tannir El Tayara¹, Christine Walczak¹, Andreas Volk¹, Marc Dhenain¹, ²

¹Institut Curie, Orsay, France; ²CEA-CNRS URA 2210, Orsay, France

                  966.      Cerebral Magnetic Resonance Angiography of the Mouse Lemur Primate

Nadine El Tannir El Tayara¹, Fabienne Aujard², Jean Luc Picq³, Andreas Volk¹, Marc Dhenain¹, ⁴

¹Institut Curie, Orsay, France; ²CNRS UMR 5176, Brunoy, France; ³Paris 8 University, EA 2027, Saint-Denis, France; ⁴CEA-CNRS URA 2210, Orsay, France

                  967.      T1 Relaxation in Mouse Brain at 9.4 and 17.6 Tesla

Rob C.G. van de Ven¹, Bianca Hogers¹, Arn Ma Ja Ms van den Maagdenberg¹, Rune R. Frants¹, Huub J. de Groot², Rob E. Poelmann¹, Suzanne R. Kiihne², Louise van der Weerd¹

¹Leiden University Medical Centre, Leiden, Netherlands; ²Leiden University, Leiden, Netherlands

                  968.      Enhanced T₂ Contrast for MR Histology of the Mouse Brain

Anjum Ali Sharief¹, ², G Allan Johnson²

¹Duke University, Durham, North Carolina, USA; ²Duke University Medical Center, Durham, North Carolina, USA

                  969.      Age Dependence of Transverse Relaxation at 3.0 T in Normal Human Brain

Jianli Wang¹, Xiaoyu Sun¹, Erin Zimmermann¹, Robert Grunfeld¹, Mark D. Meadowcroft¹, James R. Connor¹,

Michael B. Smith¹, Qing X. Yang¹

¹Penn State College of Medicine, Hershey, Pennsylvania, USA 


 

John F. Schenck¹, Earl A. Zimmerman², David L. Henderson¹

¹GE Global Research, Schenectady, New York, USA; ²Albany Medical College, Albany, New York, USA

                  971.      T2* Relaxometry for Quantitative MR Imaging of Iron Deposits in Substantia Nigra of Parkinson’s Disease Brain

Eunhee Kim¹, Jung Hee Lee¹, Sung Tae Kim¹, Won Yong Lee¹, Hong Sik Byun¹

¹Samsung Medical Center Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

                  972.      Impact of Spatial Distribution of T2 and T1 Lesion Volume on Disability and Brain Atrophy

Michael G. Dwyer¹, Sara Hussein¹, Nadir Abdelrahman¹, Viritha Yella¹, Niels P. Bergsland¹, Robert Zivadinov¹

¹Buffalo Neuroimaging Analyis Center, Buffalo, New York, USA

                  973.      Fluid-Attenuated T_1ρ of the Human Brain In Vivo

Ari Borthakur¹, Gul Moonis¹, Laura Spece¹, Elias R. Melhem¹, Christopher M. Clark¹, John Q. Trojanowski¹,

Virginia M.-Y. Lee¹, Ravinder Reddy¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA

                  974.      Changes in Brain Tissue Distribution and T2 Relaxation Time in Early Onset Type-1 Diabetes

Robert Mark Wellard¹, Gaby Pell¹, Debbie Rankin², Debra Boyce², Graeme David Jackson¹, George Werther², Elisabeth Northam²

¹Brain Research Isntitute, Melbourne, Victoria, Australia; ²Royal Children's Hospital, Melbourne, Victoria, Australia

                  975.      Mouse Brain Iron Distribution: Histochemical and Quantitative MRI (7T) Assessment

Sang-Pil Lee¹, Maria F. Falangola², ³, Jens H. Jensen², Hanzhang Lu², Ralph A. Nixon³, Karen Duff³,

Joseph A. Helpern², ³

¹University of Kansas Medical Center, Kansas City, Kansas, USA; ²New York University School of Medicine, New York, New York, USA; ³Nathan Kline Institute, Orangeburg, New York, USA

                  976.      Use of Double Inversion Recovery for Characterizing Diffusion of Myelin Water

Trevor Andrews¹, Michael Osborne¹, Mark D. Does¹

¹Vanderbilt University, Nashville, Tennessee, USA

                  977.      Comparison of Magnetization Transfer Ratios in White Matter and Gray Matter of Neonatal, Juvenile,
                                and Adult Rats

Rae Anne Kokotailo¹, Tadeusz Foniok², Min Qiao², Boguslaw Tomanek, ¹², Ursula I. Tuor, ¹²

¹University of Calgary, Calgary, Alberta, Canada; ²Institute for Biodiagnostics (West), Calgary, Alberta, Canada

                  978.      Does Repeated Injections of an Iron-Based Contrast Agent Lead to an Accumulation of
                                Iron in the Brain Parenchyma?

Samuel Valable¹, ², Christoph Segebarth¹, ², Chantal Remy¹, ², Emmanuel Barbier¹, ²

¹U594, Grenoble, F-38043, France; ²Univ grenoble 1, Grenoble, F-38043, France

                  979.      A 3T MRI Study of Brain Iron Deposition in Parkinson’s Disease and MSA Patients Using PRIME

Lauren Wallis¹, Richard Grunewald¹, Harriet Joy², Paul Griffiths¹, Martyn Paley¹

¹University of Sheffield, Sheffield, Yorkshire, UK; ²University of Southampton, Southampton, Hampshire, UK

                  980.      High Resolution MR Imaging Reveals the Angioarchitecture of Human Cerebral Cavernous Malformations

Palamadai Nilakantan Venkatasubramanian¹, ², Robert Shenkar¹, Jin Chen Zhao¹, Issam Awad¹, Alice Wyrwicz¹

¹ENH Research Institute, Evanston, Illinois, USA; ²Nothwestern University School of Medicine, Chicago, Illinois, USA

                  981.      MP-RAGE Compared to 3D IR SPGR for Optimal T1 Contrast and Image Quality in the Brain at 3T

Chen Lin¹, Robert E. Watson¹, Heidi A. Ward¹, Charlotte H. Rydberg¹, Robert J. Witte¹, Matt A. Bernstein¹

¹Mayo Clinic College of Medicine, Rochester, Minnesota, USA

                  982.      Secular-T2  MRI: Quantitative MRI of the Cerebrum and Cerebellum in 24 Subjects

Suzuko Suzuki¹, Osamu Sakai¹, Hernán Jara¹

¹Boston University School of Medicine, Boston, Massachusetts, USA 


 

Eung Y. Kim¹, Xavier Golay², ³, Seung-Koo Lee¹, Sei Y. Kim¹, Dong J. Kim¹, Jinna Kim¹, Sam S. Kim⁴, Dong I. Kim¹

¹Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Republic of Korea; ²Singapore Bioimaging Consortium, ASTAR, Singapore, Singapore; ³National Neuroscience Institute, Singapore, Singapore; ⁴Kangwon National University College of Medicine, Chunchon, Republic of Korea

                  984.      Examination of White Matter Abnormalities in Cocaine Dependence Using Multi-Slice T2 Relaxography

Bryon A. Mueller¹, ², Sheila M. Specker¹, Logi Vidarsson³, Jeff R. Wozniak¹, John M. Pauly³, Kelvin O. Lim¹, ²

¹University of Minnesota, Minneapolis, Minnesota, USA; ²Center for Magnetic Resonance Research, Minneapolis, Minnesota, USA; ³Stanford University, Stanford, California, USA



 

Spinal Cord MRI

                  985.      Preliminary Application Study of MR Perfusion Imaging and Diffusion Tensor Imaging in
                                Tumor Like Lesions in the Cervical Spinal Cord

Xiang Liu¹, Wei Tian¹, Yoshimitsu Ohgiya², Sven Ekholm¹, Per-Lennart Westesson¹

¹University of Rochester School of Medicine & Dentistry, Rochester, New York, USA; ²University of Rochester School of Medicine & Dentistry, Rochestrer, New York, USA

                  986.      Diffusion Tensor MRI of the Spinal Cord in Amyotrophic Lateral Sclerosis

Paola Valsasina¹, ², Beatrice Benedetti¹, ², Domenico Caputo¹, Michele Perini³, Massimo Filippi¹, ²

¹Fondazione Don Gnocchi, Milan, Italy, Italy; ²Hospital San Raffaele, Milan, Italy, Italy; ³Ospedale di Gallarate, Gallarate, Italy, Italy

                  987.      Diffusion Tensor MR Imaging of the Spinal Cord in Patients with Multiple Sclerosis

Yoshimitsu Ohgiya¹, ², Masaki Oka³, Akio Hiwatashi², Xiang Liu², Naoya Kakimoto², Tadashi Kitahara⁴,

Takehiko Gokan¹, Sven Ekholm², Per-Lennart Westesson²

¹Showa University School of Medicine, Tokyo, Japan; ²University of Rochester Medical Center, Rochester, New York, USA; ³Kikunakinen Hospital, Yokohama, Japan; ⁴Showa University Fujigaoka Hospital, Yokohama-shi, Japan

                  988.      Diffusion Anisotropy in WM Depends on Myelin Content in a Diffusion Time-Dependent Manner:
                                Evidence from High B Value Q-Space Diffusion MR of Myelin Deficient Rat Spinal Cord

Inbal Eti Biton¹, Ian D. Duncan², Yoram Cohen¹

¹Tel-Aviv University, Tel-Aviv, Israel; ²University of Wisconsin-Madison, Madison, Wisconsin, USA

                  989.      DWI Assessment of a Transgenic Mouse Model for ALS

Haitham Abdelmoaty¹, Melinda West¹, Yasvir Tesiram¹, Andrew Abbott¹, Rebecca Blindauer¹, Kenneth Hensley¹,

Rheal A. Towner¹

¹Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA

                  990.      In Vivo Regional Diffustion Tensor Metrics of  Rodent Spinal Cord

Aparna A. Deo¹, Khader M. Hasan², Ponnada A. Narayana²

¹University of Houston, Houston, Texas, USA; ²University of Texas, Houston, Texas, USA

                  991.      Contrast-Enhanced High Resolution MR Angiography of the Rat Spinal Region

Ketan B. Ghaghada¹, ², Kurt H. Bockhorst³, Srinivasan Mukundan⁴, ⁵, Ponnada A. Narayana³, Ananth V.

Annapragada, ¹²

¹University of Houston, Houston, Texas, USA; ²University of Texas Health Science Center, Houston, Texas, USA; ³University of Texas-Houston Medical School, Houston, Texas, USA; ⁴Duke University Medical Center, Durham, North Carolina, USA; ⁵Duke University, Durham, North Carolina, USA

                  992.      MRI of Blood-Spinal Cord Barrier Disruption in Mice with Experimental Autoimmune Encephalomyelitis

Angela Eileen Schellenberg¹, Richard Buist¹, V Wee Yong², Marc R. Del Bigio¹, James Peeling¹

¹University of Manitoba, Winnipeg, Manitoba, Canada; ²University of Calgary, Calgary, Alberta, Canada

Hideki Hyodoh¹, Hidenari Akiba¹, Mitsuharu Tamakawa¹, Kazusa Hyodoh¹, Naoya Yama¹, Taishi Sato¹,

Yuriko Kawaai¹, Masato Hareyama¹

¹Sapporo Medical University, Sapporo, Japan

                  994.      Labeling Transected Axons with Intracellular Gd-DTPA for Micro-MRI of Lamprey Spinal Cord Injury

Alexander C. Wright¹, Li-Qing Jin¹, Guixin Zhang¹, Suzanne L. Wehrli², Michael E. Selzer¹, David B. Hackney¹,

Felix W. Wehrli¹

¹University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA; ²Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

                  995.      Dynamic In Vivo T1 Relaxation Measurements of Mouse Spinal Cord for Manganese-Enhanced MRI at 9.4 T

Xiping Liu¹, Guofan Xu¹, Gaohong Wu¹, Qian Yin¹, Shi-Jiang Li¹

¹Medical College of Wisconsin, Milwaukee, Wisconsin, USA

                  996.      Detection of Ipsilateral and Contralateral Activation Components in Unilateral Fingers-Tapping
                                Using Spinal BOLD fMRI

M. C. Ng¹, ², Edward X. Wu, H. F. Lau, Yong Hu, Edward S. Yang¹, D. K. Luk

¹The Jockey Club MRI Centre, The University of Hong Kong, Pokfulam, Hong Kong, People’s Republic of China; ²Department of Orthopaedics and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong, People’s Republic of China

                  997.      Characterization of Spinal Cord Motion:  a Source of Errors in Spinal fMRI?

Chase R. Figley¹, Patrick W. Stroman¹

¹Queen's University, Kingston, Ontario, Canada

Perfusion Imaging in Animal Models

                  998.      Real Time Monitoring of Hyperosmolar Blood Brain Barrier Disruption Using MRI

Marie Blanchette¹, Martin Pellerin¹, Luc Tremblay¹, David Fortin¹, Martin Lepage¹

¹Université de Sherbrooke, Sherbrooke, QC, Canada

                  999.      Implementation and Evaluation of an MRI Protocol for Assessment of Cerebrovascular Reserve
                                in the Rhesus Monkey – Characterizing the Aging Brain

Alexandre Coimbra¹, Marie A. Holahan¹, Yevgen Tymofyeyev¹, Richard Hargreaves¹, Jacquelynn J. Cook¹,

Donald S. Williams¹

¹Merck Research Laboratories, West Point, Pennsylvania, USA

                  1000.    Steady-State Quantification of δR₂ (SSTAR2) with Combidex for Measuring Cerebral Blood Volume

Jeff Frank Dunn¹, Debbie Anne Kelly¹, Cheryl Rae McCreary¹, Randy Tyson², Dave Kirk¹, Tad Foniok²

¹University of Calgary, Calgary, AB, Canada; ²National Research Council, Calgary, AB, Canada

                  1001.    Rapid Steady State T1 Method for Cerebral Blood Volume Fraction Mapping: Sensitivity
                                Determination Under Hypercapnia

Adriana Teodora Perles-Barbacaru¹, ², Hana Lahrech¹, ²

¹INSERM, U594, Grenoble, F-38043, France; ²Univ Grenoble 1, Grenoble, F-38043, France

                  1002.    Quantitative Analysis of Distribution and Clearance Rate of Charged and Uncharged Gd-Chelates in Rat Brain

Paul A. Schornack¹, Ping Wang¹, Seong-Gi Kim¹

¹University of Pittsburgh, Pittsburgh, Pennsylvania, USA

                  1003.    Developing an Arterial Spin Labeling Technique for Measuring Cerebral Blood Flow in Pediatrics:
                                Comparison with Computed Tomography Perfusion

Adrian Matthew Yuri Koziak¹, ², Jeff Winter¹, ², Ting-Yim Lee¹, ², Robert Terry Thompson¹, ², Keith St. Lawrence¹, ²

¹Lawson Health Research Institute, London, Ontario, Canada; ²University of Western Ontario, London, Ontario, Canada

                  1004.    Arterial Spin Labeling Measurement of Arterial Perfusion Territories Using a Localized Labeling RF Coil

Fernando Fernandes Paiva¹, ², George Carlos Nascimento¹, Alberto Tannus², Afonso Costa Silva¹

¹National Institutes of Health, Bethesda, Maryland, USA; ²Universidade de Sao Paulo, Sao Carlos, SP, Brazil

                  1005.    Limits on Quantification of Perfusion and Capillary Permeability Surface Area Product Using FAIR ASL

John Carr¹, David Buckley¹, Jean Tessier², Geoff Parker¹

¹University of Manchester, Manchester, Greater Manchester, UK; ²AstraZeneca, Macclesfield, Cheshire, UK

Tissue Segmentation and Coregistration

                  1006.    Identifying Tissue Types in MR Imaging of Benign Prostatic Hyperplasia

Seok Ping Ang¹, Philip Daniel Allen¹, James Graham¹, Charles Edward Hutchinson¹

¹The University of Manchester, Manchester, UK

                  1007.    Can Texture Analysis of MR Images Discriminate the Severity of Hepatic Fibrosis? a Patient Study
                                with Histological Correlation

Kieren Grant Hollingsworth¹, Susan Davies², David J. Lomas¹

¹University of Cambridge, Cambridge, Cambridgeshire, UK; ²Addenbrookes Hospital, Cambridge, Cambridgeshire, UK

                  1008.    Validation and Implementation of an Automated Boundary Finding Algorithm for Muscle Anatomy Studies

Bruce M. Damon¹, Drew A. Lansdown¹, Zhaohua Ding¹

¹Vanderbilt University, Nashville, Tennessee, USA

                  1009.    Improving Automatic Tibial Medial Cartilage Segmentation by Incorporating Femoral Cartilage Compartment

Jenny Folkesson¹, Ole Fogh Olsen¹, Erik Dam¹, ², Paola Pettersen², Claus Christiansen²

¹IT University of Copenhagen, Copenhagen, DK, Denmark; ²Center for Clinical and Basic Research, Ballerup, DK, Denmark

                  1010.    Automatic 3D Registration of Trabecular Bone Images Using a Collection of Regional 2D Registrations

Jeremy Magland¹, Branamir Vasilic¹, Wei Lin¹, Felix W. Wehrli¹

¹University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

                  1011.    Fuzzy Logic Analysis and Reconstruction of Bone Structure from High-Resolution MRI

Florent Chandelier¹, David Dupuis¹, Luc Tremblay¹, Akbar Darabi¹, Gamal Baroud¹, Martin Lepage¹

¹Université de Sherbrooke, Sherbrooke, QC, Canada

                  1012.    Fuzzy C-Means Based Tissue Classification in the Presence of Noise and Field Inhomogeneity

Binjian Sun¹, ², Don P. Giddens¹, Marijn E . Brummer¹, ², John N. Oshinski¹, ²

¹Georgia Institute of Technology, Atlanta, Georgia, USA; ²Emory University, Atlanta, Georgia, USA

                  1013.    Multi-Criteria Seeded Region Growing for Multi-Contrast MRI

Arnaud Garcia¹, ², Corinne Vachier¹, Antoine Rosset², Jean-Paul Vallee²

¹ENS Cachan, CACHAN, France; ²Geneva University Hospital, Geneva, Switzerland

                  1014.    A Semi-Automatic Ventricular Border Segmentation Package Based on Multi-Phase Levelset Segmentation

Qi Duan¹, Daniel Moses², Monvadi B. Srichai², Vinay M. Pai², Andrew F. Laine¹

¹Columbia University, New York, New York, USA; ²New York University Medical Center, New York, New York, USA

                  1015.    Three Dimensional Tracking of Tag Intersections in Tagged MRI

Yu Shimizu¹, XiuYi Jin², Akira Amano¹, Tetsuya Matsuda¹

¹Kyoto University, Kyoto, Japan; ²Advanced Software Technology & Mechatronics Research Institute of Kyoto, Kyoto, Japan

                  1016.    Dynamic Monitoring of the Rat Uterus Using 3D Automatic Segmentation

Erez Eyal¹, Ayelet Akselrod-Ballin¹, Meirav Galun¹, Edna Furman-Ha