Vascular Postprocessing

                  1273.    Robust Vessel Path Tracking in Imperfect Volumetric Data

Noel Christopher Codella¹, Yi Wang¹, Ramin Zabih²

¹Cornell Weill Medical College, New York, New York, USA; ²Cornell University, Ithaca, New York, USA

                  1274.    Fast, Reliable Carotid Plaque Burden Measurements with Interactive Snakes

William Sean Kerwin¹, Dongxiang Xu¹, Fei Liu¹, Norihide Takaya¹, Baocheng Chu¹, Howard Klein², William Ross²

¹University of Washington, Seattle, Washington, USA; ²Pathway MRI, Inc., Seattle, Washington, USA

                  1275.    Neovascularization in the Carotid Atherosclerotic Plaque Can Be Identified by Dynamic
                                Contrast-Enhanced High Resolution 3TMRI

Jing Han¹, Jian Cai¹, Lin Ma¹, Xin Liu¹

¹PLA general Hospital, Beijing, People’s Republic of China

                  1276.    Robust Image Segmentation Through Outlier Handling Application to Automatic Plaque Burden Assessment

Karim Lekadir¹, Robert Merrifield¹, Niall Keenan², Dudley Pennell², Guang-Zhong Yang¹

¹Imperial College, London, UK; ²Royal Brompton and Harefield Trust, London, UK

                  1277.    Reproducibility Assessment of Morphology-Enhanced Probabilistic Plaque Segmentation (MEPPS)
                                on Two Baseline Magnetic Resonance Scans

Fei Liu¹, Dongxiang Xu¹, Baocheng Chu¹, Tobias Saam¹, Norihide Takaya¹, Hunter Underhill¹, Thomas S.

Hatsukami¹, ², Chun Yuan¹, William S. Kerwin¹

¹University of Washington, Seattle, Washington, USA; ²VA Puget Sound Health Care System, Seattle, Washington, USA

                  1278.    Aorta Segmentation Using Elliptical Deformable Templates

Ersin Bayram¹, ², William Gregory Hundley³, Craig Alan Hamilton¹

¹Virginia Tech-Wake Forest University, Winston-Salem, North Carolina, USA; ²GE Healthcare, Waukesha, Wisconsin, USA; ³

Wake Forest University School of Medicine, Winston Salem, North Carolina, USA

                  1279.    Reproducibility Study of Wall Segmentation Approach in Evaluating PAD Patient with MRI

Dongxiang Xu¹, Timothy J. Carroll², Lu Tian², James Carr², Kiang Liu², Debiao Li², Mary M. McDermott², Chun Yuan¹

¹University of Washington, Seattle, Washington, USA; ²Northwestern University, Chicago, Illinois, USA

                  1280.    Complex Subtraction – a Flow-Independent Method for Vessel Wall Imaging Shortly After Gadofluorine Injection

Ioannis Koktzoglou¹, Bernd Misselwitz², Hanns-Joachim Weinmann², Debiao Li¹

¹Northwestern University, Chicago, Illinois, USA; ²Schering AG, Berlin, Germany


 

                  1281.    Potentiation of Cyclophosphamide Chemotherapy Using the Antiangiogenic Drug Thalidomide: 
      Importance of Optimal Scheduling to Exploit the Normalization Window of the Tumor Vasculature

Jerome Segers¹, Vincent Difazio², Reginald Ansiaux¹, Philippe Martinive¹, Olivier Feron¹, Pierre Wallemacq²,

Bernard Gallez¹

¹UCL, Woluwe, Bruxelles, Belgium; ²Saint-Luc Hospital, Woluwe, Bruxelles, Belgium

                  1282.    New Formulation of EPR Oxygen Sensors Dispersed in Thermo-Reversible Hydrogels

Mustapha Dinguizli¹, Nelson Beghein¹, Bernard Gallez¹

¹Université catholique de Louvain, Brussels, B, Belgium

                  1283.    Modulated Radiation Force of US as Shear Wave Source in Microscopic MRE

Thomas J. Royston¹, Shadi F. Othman¹, Faik Can Meral¹, Bulent B. Ozer¹, Richard L. Magin¹

¹University of Illinois at Chicago, Chicago, Illinois, USA

                  1284.    Performance Comparison of the Spatial Autocorrelation Function and the Mean Intercept-Length in
                                the Determination of Trabecular Bone Anisotropy in the In Vivo Environment

Michael Jeffrey Wald¹, Branimir Vasilic¹, Punam K. Saha¹, Felix W. Wehrli¹

¹Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

                  1285.    An Automated On-The-Fly Detection and Correction Procedure for EPR Imaging Data Acquisition

Rizwan Ahmad¹, Bradley Clymer¹, Yuanmmu Deng¹, Deepti Vikram¹, Sergey Petryakov¹, Periannan Kuppusamy¹,

Jay L. Zweier¹

¹The Ohio State University, Columbus, Ohio, USA

                  1286.    Application of Over Magnetic Field Modulation in EPR Oximetry

Yuanmu Deng¹, Ramasamy P. Pandian¹, Rizwan Ahmad¹, Periannan Kuppusamy¹, Jay L. Zweier¹

¹The Ohio State University School of Medicine, Columbus, Ohio, USA

Human Lung Imaging Techniques

                  1287.    Quantitative Contrast-Enhanced Perfusion Measurements of the Human Lung

Markus Oechsner¹, Matti Mühlhäusler¹, Peter M. Jakob¹, Meinrad Beer¹, Dietbert Hahn¹, Matthias Beissert¹,

Matthias Spindler¹, Herbert Köstler¹

¹University of Würzburg, Würzburg, Bavaria, Germany

                  1288.    Comparison of Hyperpolarized 3-He Administration Methods in Healthy and Diseased Subjects

Neil Woodhouse¹, Jim M. Wild¹, Gary H. Mills², Sally Fleming², Stan Fichele¹, Edwin JR van Beek³

¹University of Sheffield, Sheffield, South Yorkshire, UK; ²Sheffield Teaching Hospitals NHS Trust, Sheffield, South Yorkshire, UK; ³University of Iowa, Iowa City, Iowa, USA

                  1289.    Short-Breath-Hold PO2 Imaging with 3He: Initial Experience in Lung Disease

G Wilson Miller¹, Eduard E. de Lange¹, Jaime F. Mata¹, Jing Cai¹, Gordon D. Cates¹, W A. Tobias¹,

John P. Mugler III¹

¹University of Virginia, Charlottesville, Virginia, USA

                  1290.    Regional Ventilation Differences at Large Lung Volumes Assessed Using Hyperpolarized ³He MRI

Jessica Dickey Gereige¹, Yanping Sun¹, Joey Karim Mansour¹, Francine L. Jacobson¹, ², Peter Lindholm³,

James P. Butler², Stephen H. Loring⁴, Massimo Ferrigno¹, Mitchell S. Albert¹

¹Brigham and Women's Hospital, Boston, Massachusetts, USA; ²Harvard Medical School, Boston, Massachusetts, USA; ³Karolinska Institutet, Stockholm, Sweden; ⁴Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

                  1291.    Real-Time MR Imaging and Tracking of Regional Lung Motion During Forced Breathing Maneuvers

Abram Voorhees¹, Jing An¹, Kenneth I. Berger¹, Roberta M. Goldring¹, Leon Axel¹, Qun Chen¹

¹New York University School of Medicine, New York, New York, USA

                  1292.    Towards a Normative Lung Atlas: Validation of Physiologically Appropriate Temporal
                                Reparameterization of Dynamic Lung MR Sequences

Tessa Sundaram¹, Shigeto Kubo², Masaya Takahashi², James Gee¹, Hiroto Hatabu²

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA; ²Beth Israel Deaconess Medical Center, Harvard University, Boston, Massachusetts, USA

                  1293.    Optimal Breathing Protocol for Dynamic Contrast Enhanced MRI of Solitary Pulmonary Nodule at 3T

Aya Kino¹, Masaya Takahashi¹, Takeshi Kubo¹, Danielle Coute¹, Simon K. Ashiku¹, J. Anthony Parker¹,

Malcolm M. DeCamp¹, Robert E. Lenkinski¹, Hiroto Hatabu¹

¹Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

                  1294.    T₁ and D of Perfluorocarbon-O₂ Mixtures for Lung Imaging

Yulin V. Chang¹, Mark S. Conradi¹

¹Washington University, St. Louis, Missouri, USA

                  1295.    Rapid Production of Hyperpolarized 3He Gas for MRI

Brian Saam¹, Richard E. Jacob², Benjamin C. Anger¹, Kevin R. Minard²

¹University of Utah, Salt Lake City, Utah, USA; ²Pacific Northwest National Laboratory, Richland, Washington, USA

                  1296.    Using Laser Frequency Narrowing Techniques to Improve Production of Hyperpolarized Xe for
                                Imaging and Surface Analysis

Cavin Lee Talbot¹, Marlies Elly Joy Friese¹, Halina Rubinsztein-Dunlop¹, Katie M. Baldwin¹, Andrew K. Whittaker¹, Ian Brereton¹, Norman R. heckenberg¹, David M. Doddrell¹, Deming Wang¹

¹The University of Queensland, Brisbane, Queensland, Australia

                  1297.    Hyperpolarized 129Xe Human Pulmonary Gas Exchange with 3-Point Dixon Technique

Iga Muradian¹, ², Samuel Patz², J. P. Butler³, G. P. Topulos², M. I. Hrovat⁴, S. Covrig¹, S. Ketel¹, I. Russet¹,

F. W. Hersman¹

¹University of New Hampshire, Durham, New Hampshire, USA; ²Brigham and Women's Hospital, Boston, Massachusetts, USA; ³Harvard School of Public Health, Boston, Massachusetts, USA; ⁴Mirtech Inc., Brockton, Massachusetts, USA

                  1298.    Quantification of Pulmonary Perfusion Using SEEPAGE

André Fischer¹, Eberhard Daniel Pracht¹, Peter Michael Jakob¹

¹University of Würzburg, Würzburg, Bavaria, Germany

                  1299.    Structural Lung Parenchyma: Breath-Hold Isotropic Imaging Using 3D SSFP

Piotr Wielopolski¹, Maarten Lequin¹

¹Erasmus MC, Rotterdam, ZH, Netherlands

                  1300.    Radial MRI of the Human Lung

Falko Lohberger¹, Michael Amann¹, Lothar R. Schad¹

¹German Cancer Research Center, Heidelberg, Germany

                  1301.    MR Imaging of the Thorax During Whole-Body MRI: Evaluation of Different MR Sequences
                                and Comparison to Thoracic CT

Bernd B. Frericks¹, Bernhard Meyer¹, Tanja Nentwig², Karl J. Wolf¹, Frank K. Wacker¹

¹Charité, Campus Benjamin Franklin, Berlin, Germany; ²Imaging Science Institute, Siemens, Berlin, Germany

                  1302.    A Self-Navigated Feedback Method for Fast Gradient-Echo Imaging of Hyperpolarized 3He
                                Using Variable Flip Angles

G Wilson Miller¹, John P. Mugler III¹, Jing Cai¹, Jaime Mata¹, Eduard E. de Lange¹, Gordon D. Cates¹, W A. Tobias¹, James R. Brookeman¹

¹University of Virginia, Charlottesville, Virginia, USA

                  1303.    Parallel Phase-Encoded Images with Hyperpolarized Gas

Xavier Maître¹, Olivier Girard¹, Ludovic De Rochefort¹, Clarisse Halawani¹, Emmanuel Durand¹, Luc Darrasse¹

¹CNRS - Universite Paris Sud, Orsay, France

                  1304.    Human Pulmonary Gas State Imaging at 0.2T with Hyperpolarized 129Xe

Samuel Patz¹, Iga Muradian, ¹², Mirko I. Hrovat³, James P. Butler⁴, George P. Topulos¹, Steven Ketel²,

 Iulian C. Ruset², Silviu Covrig², F. William Hersman²

¹Brigham and Women's Hospital, Boston, Massachusetts, USA; ²University of New Hampshire, Durham, New Hampshire, USA; ³Mirtech, Inc., Brockton, Massachusetts, USA; ⁴Harvard School of Public Health, Boston, Massachusetts, USA

                  1305.    Human Pulmonary PO2 at 0.2T with Hyperpolarized 129Xe

Mirko I. Hrovat¹, Iga Muradian², Steven Ketel², F. William Hersman², Samuel Patz³, James P. Butler⁴,

George P. Topulos³, Iulian C. Ruset², Silviu Covrig²

¹Mirtech, Inc., Brockton, Massachusetts, USA; ²University of New Hampshire, Durham, New Hampshire, USA; ³Brigham and Women's Hospital, Boston, Massachusetts, USA; ⁴Harvard School of Public Health, Boston, Massachusetts, USA

                  1306.    Optimised FLASH Sequences for Examinations of the Human Lung at 0.2 Tesla

Markus Oechsner¹, Meinrad Beer¹, Eberhard D. Pracht¹, Herbert Köstler¹, Dietbert Hahn¹, Markus Weininger¹, Matthias Beissert¹, Peter M. Jakob¹

¹University of Würzburg, Würzburg, Bavaria, Germany

                  1307.    Oxygen-Enhanced MRI of the Lung at 3 Tesla: Feasibility and T1 Relaxation Times

Olaf Dietrich¹, José G. Raya¹, Ulrike Fasol¹, Michael Peller¹, Maximilian F. Reiser¹, Stefan O. Schoenberg¹

¹Ludwig Maximilian University of Munich, Munich, Germany

                  1308.    Half-Fourier Single-Shot Turbo Spin-Echo (HASTE) of the Lung at 3T: Feasibility Study
                                Using Parallel Imaging with 32-Receiver Channel Technology

Christian Fink¹, Olaf Dietrich¹, Roger Eibel¹, Peter Herzog¹, Daniel Theisen¹, Titus Lanz², Maximilian F. Reiser¹, Stefan O. Schoenberg¹

¹University of Munich, Munich, NA, Germany; ²Rapid Biomedical, Rimpar, NA, Germany

                  1309.    Comparing Gd Contrast and Non-Contrast Lung Perfusion Imaging at 1.5T and 3T

Sergei I. Obruchkov¹, Michael D. Noseworthy¹

¹McMaster University, Hamilton, Ontario, Canada

                  1310.    Influence of Inspiration Level on Hyperpolarized ³He ADC in Healthy Lungs

Lise Vejby Søgaard¹, Trine Stavngaard¹, Jörg Schmiedeskamp², Wolfgang G. Schreiber³

¹Copenhagen University Hospital, Hvidovre, Denmark; ²Johannes Gutenberg-University, Mainz, Germany; ³Johannes Gutenberg-University Medical School, Mainz, Germany

                  1311.    Nonlinear Fitting Method for High Resolution Mapping of Apparent Diffusion Coefficient (ADC)
                                by Hyperpolarized 3He

JiangSheng Yu¹, Stephen Kadlecek¹, Masaru Ishii², John MacDuffie Woodburn¹, Kiarash Emami¹, Vahid Vahdat¹, Sheeva Rajaei¹, Frank Hammond¹, Letitia R. Cheatham¹, Benjamin M. Brainard¹, Timothy W.I. Clark³,

David A. Lipson¹, Warren B. Gefter¹, Rahim R. Rizi¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA; ²Johns Hopkins University, Baltimore, Maryland, USA; ³New York University, New York, New York, USA

                  1312.    Time Dependence of ³He Diffusion in the Human Lung: Measurement in the Long-Time Regime
      Using Stimulated Echoes

Chengbo Wang¹, Grady W. Miller¹, Talissa A. Altes, ^1,2, Eduard E. de Lange¹, John P. Mugler, III¹

¹University of Virginia, Charlottesville, Virginia, USA; ²Children's Hospital of Philadephia, Philadelphia, Pennsylvania, USA

                  1313.    Evidence of Background-Gradient Effects in GRE-Based ³He Diffusion MRI

John P. Mugler III¹, Jaime F. Mata¹, Talissa A. Altes¹, ², G. Wilson Miller¹, Eduard E. de Lange¹, William A. Tobias¹, Gordon D. Cates Jr. ¹, James R. Brookeman¹

¹University of Virginia, Charlottesville, Virginia, USA; ²Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

                  1314.    The Relationship Between ³He ADC and Lung Volume

Jason C. Woods¹, David S. Gierada¹, Yulin V. Chang¹, Barbara A. Lutey¹, Andrew J. Bierhals¹, Dmitriy A. Yablonskiy¹, Mark S. Conradi¹

¹Washington University, St Louis, Missouri, USA

                  1315.    Single Scan Acquisition of Hyperpolarized 3He Ventilation Images and ADC Images Using a Hybrid 2D Sequence

Jim M. Wild¹, Neil Woodhouse¹, Kevin Teh¹

¹University of Sheffield, Sheffield, Yorkshire, UK

                  1316.    How to Optimize b-Values for In Vivo Lung Morphometry with ³He Diffusion MR

Alexander L. Sukstanskii¹, Yulin V. Chang¹, G. Larry Bretthorst¹, Mark S. Conradi¹, Dmitriy A. Yablonskiy¹

¹Washington University, St. Louis, Missouri, USA

                  1317.    Diffusion Corrected Reconstructions of Partial Pressure of Oxygen Using Polarized Gas MRI

Masaru Ishii¹, ², JiangSheng Yu², Vahid Vahdat², John MacDuffie Woodburn², Sheeva Rajaei², Kiarash Emami²,

Frank Hammond², Stephen Kadlecek², Rahim R. Rizi²

¹Johns Hopkins University, Baltimore, Maryland, USA; ²University of Pennsylvania, Philadelphia, Pennsylvania, USA

                  1318.    Quantification of Lung Tumor Volume and Rotation During Respiration Using 3D Dynamic Parallel
                                MRI with View Sharing – Preliminary Results

Christian Plathow¹, Max Schoebinger², Christian Fink³, Holger Hof², Claus Claussen⁴, Heinz-Peter Meinzer²,

Hans-Ulrich Kauczor²

¹Eberhard-Karls-University Tuebingen, Tuebingen, Baden-Württemberg, Germany; ²German Cancer Research Center, Heidelberg, Baden-Wuerttemberg, Germany; ³University of Munich, Munich, Bavaria, Germany; ⁴Eberhard-Karls University, Tuebingen, Baden-Wuerttemberg, Germany

                  1319.    Oxygen-Enhanced MRI of the Lung: Optimized Calculation of Difference Images

Olaf Dietrich¹, Michael Peller¹, Ulrike Fasol¹, Christoph Losert¹, Konstantin Nikolaou¹, Maximilian F. Reiser¹,

Stefan O. Schoenberg¹

¹Ludwig Maximilian University of Munich, Munich, Germany

                  1320.    A Diffusion Coefficient Distribution Model to Describe the B-Value Dependence of ADC in
                                Diffusion-Weighted Hyperpolarized Gas MRI

Rafael Luis O'Halloran¹, James H. Holmes¹, Andrew L. Alexander¹, Sean B. Fain¹

¹University of Wisconsin, Madison, Wisconsin, USA

                  1321.    Computer Simulations and Experimental Tests of Surface-To-Volume Measurements Using 3He NMR

Michael Carl¹, G Wilson Miller¹, John P. Mugler III¹, Gordon D. Cates¹

¹University of Virginia, Charlottesville, Virginia, USA

                  1322.    Long-Range Diffusion of ³He in Lungs: Evidence for Collateral Ventilation Pathways from
                                Comparison of Computer Simulations and Measurements

Seth-Emil Thomas Bartel¹, Susan E. Haywood¹, Mark S. Conradi¹, Jason C. Woods¹, David S. Gierada¹

¹Washington University, St. Louis, Missouri, USA

                  1323.    Experimental Study of Gas Diffusion in a Pulmonary Acinus Model

Dayane Habib¹, Denis Grebenkov¹, Xavier Maître¹, Ludovic De Rochefort¹, Emmanuel Durand¹, Geneviève Guillot¹

¹Université Paris-Sud Bât.220, Orsay, France

                  1324.    Quantitative MR Imaging of 3He Gas Transport in Model Airways

Kevin R. Minard¹, Richard E. Jacob¹

¹Pacific Northwest National Laboratory, Richland, Washington, USA

                  1325.    Velocimetry of Hyperpolarized Rare Gases: Phantom Studies and First In Vivo Results

Wolfgang Kilian¹, Max Strowig¹, Frank Seifert¹

¹Physikalisch-Technische Bundesanstalt, 10587 Berlin, Germany

                  1326.    Quantitation of Pulmonary Structure Via Registration and Normalization of Serial ³He MR Images

James Gee¹, Tessa Sundaram¹, Brian Avants¹, Pablo Burstein¹, Paul Yushkevich¹, Hui Zhang¹, Ingrid Casselbrant², Per Akeson², Goran Pettersson³, Brad Wyman⁴, Barry Peterson⁴

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA; ²Malmo University Hospital, Malmo, Sweden; ³General Electric, Malmo, Sweden; ⁴Pfizer, Groton, Connecticut, USA



 

Lung Imaging: Animal Model & Hyperpolarized Gases

                  1327.    Improved Determination of Hyperpolarized ¹²⁹Xe T₁ in the Rat Brain

Xin Zhou¹, Mary Lynn Mazzanti¹, Jianbing James Chen¹, Joey Karim Mansour¹, Jessica Dickey Gereige¹,

Arvind K. Venkatesh¹, Yanping Sun¹, Robert V. Mulkern¹, Mitchell S. Albert¹

¹Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA

                  1328.    Hyperpolarized 13C MRI Cineangiography of Pulmonary Perfusion

Masaru Ishii¹, Kiarash Emami², Stephen Kadlecek², Sheeva Rajaei², JiangSheng Yu², John MacDuffie Woodburn², Frank Hammond², Vahid Vahdat², J Stefan Petersson³, Klaes Golman³, Rahim R. Rizi²

¹Johns Hopkins University, Baltimore, Maryland, USA; ²University of Pennsylvania, Philadelphia, Pennsylvania, USA; ³GE Healthcare, Malmo, Sweden

                  1329.    Parametric Mapping of Ex-Vivo Mouse Lung at 9.4 Tesla with Air-Inflation Fixation Method

Hidemasa Uematsu¹, Suzanne L. Wehrli², Masaya Takahashi³, Hiroto Hatabu³, Toshio Asakura²

¹University of Fukui, Fukui, Japan; ²Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; ³Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, US

                  1330.    A Delivery System for Hyperpolarized 129Xe MRI of Small Animal Lungs

Shing-Jong Huang¹, Chao-Hsien Hsieh², Jyh-Horng Chen², Shang-Bin Liu¹, Yeun-Chung Chang³

¹Academia Sinica, Taipei, Taiwan; ²National Taiwan University, Taipei, Taiwan; ³National Taiwan University Hospital and College of Medicine, Taipei, Taiwan

                  1331.    Respiratory-Gated 3D Fast Spin-Echo for Oxygen-Enhanced MR Imaging of Mice Lungs

Kristina Nancy Watt¹, ², Brian J. Nieman¹, ², Jonathan Bishop¹, Ryan Mark Henkelman¹, ², Josette Chen¹, ²

¹Mouse Imaging Centre (MICe), Hospital for Sick Children, Toronto, ON, Canada; ²University of Toronto, Toronto, ON, Canada

                  1332.    Experimental Validation of a Model for the Field Dependence of the SNR of Hyperpolarized
                                Noble Gas MR Imaging of Rodent Lungs In Vivo

Juan Parra-Robles¹, William Dominguez Viqueira¹, Alexei Ouriadov¹, Wilfred Lam¹, Nishard Abdeen²,

Giles E. Santyr¹

¹Robarts Research Institute, London, Ontario, Canada; ²Carleton University, Ottawa, Ontario, Canada

                  1333.    Registered ³He Ventilation and ¹H Perfusion Dynamic Contrast Enhanced MRI in the Rodent Lung

Nilesh N. Mistry¹, Jim R. Pollaro¹, Laurence W. Hedlund¹, Glenn Allan Johnson¹

¹Duke University, Durham, North Carolina, USA

                  1334.    Comparison of Hyperpolarized Helium MR Imaging of Regional Ventilation with Xenon-Enhanced CT in Rodents

Giles Santyr¹, Wilfred Lam¹, Alexei Ouriadov¹, Maria Drangova¹, David McCormack², David Holdsworth¹

¹Robarts Research Institute, London, Ontario, Canada; ²London Health Sciences Centre, London, Ontario, Canada

                  1335.    Measurement of Nonlinear Decay of Alveolar Partial Pressure of Oxygen in Mice Using 3He-MRI

Katarzyna Cieslar¹, Hasan Alsaid², Vasile Stupar², Sophie Gaillard², Rachida Fissoune², Emmanuelle Canet-Soulas², Yannick Cremillieux²

¹Jagiellonian University, Institute of Physics, Krakow, Poland; ²Univeriste Claude Bernard Lyon1, Lyon, France

                  1336.    In Vivo Measurement of T2 Relaxation of Mouse Lungs During Inspiration and Expiration

Lars E. Olsson¹, Paul D. Hockings¹

¹AstraZeneca, Mölndal, Sweden

                  1337.    Alveolar Oxygen Partial Pressure and Oxygen Depletion Rate Mapping in Rats Using 3He-MRI

Katarzyna Cieslar¹, Vasile Stupar², Sophie Gaillard², Emmanuelle Canet-Soulas², Yannick Cremillieux²

¹Jagiellonian University, Institute of Physics, Krakow, Poland; ²Univeriste Claude Bernard Lyon1, Lyon, France

                  1338.    Retrospective Cine ³He Ventilation Imaging Under Spontaneous Breathing Conditions:
                                A Non Invasive Imaging Protocol for Small Animal Lung Function Imaging

Vasile Stupar¹, Emmanuelle Canet Soulas¹, Hasan Alsaid¹, Sophie Gaillard¹, Nicolau Beckmann²,

Yannick Crémillieux¹

¹Laboratoire de RMN, UMR CNRS5012, Université Lyon1, ESCPE, Villeurbanne, France; ²Discovery Technologies, Novartis Institutes for BioMedical Research, Basel, Switzerland

                  1339.    Detection of Pulmonary Emboli by Hyperpolarized Carbon-13 in Pig Model

Masaru Ishii¹, Stephen Kadlecek², JiangSheng Yu², Sheeva Rajaei², Kiarash Emami², Vahid Vahdat²,

John MacDuffie Woodburn², Frank Hammond², J Stefan Petersson³, Klaes Golman³, Rahim R. Rizi²

¹Johns Hopkins University, Baltimore, Maryland, USA; ²University of Pennsylvania, Philadelphia, Pennsylvania, USA; ³GE Healthcare, Malmo, Sweden

                  1340.    Nonlinear Fitting Method for the Measurements of Regional Alveolar Oxygen Pressure and Oxygen
                                Depletion Rate by Hyperpolarized 3He MRI

JiangSheng Yu¹, Kiarash Emami¹, Masaru Ishii², John MacDuffie Woodburn¹, Sheeva Rajaei¹, David Lipson¹,

Vahid Vahdat¹, Stephen Kadlecek¹, Frank Hammond¹, Timothy W.I. Clark³, Benjamin M. Brainard¹, Letitia R. Cheatham¹, Warren B. Gefter¹, Rahim R. Rizi¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA; ²Johns Hopkins University, Baltimore, Maryland, USA; ³New York University School of Medicine, New York, New York, USA

                  1341.    Diffusion Imaging with Hyperpolarized Helium MR in Surfactant Protien C Deficient Mice

Casey B. Orellana¹, Yulin V. Chang¹, Jason C. Woods¹, Richard E. Jacob¹, John A. Engelbach¹, Jeffrey A. Whitsett², Mark S. Conradi¹, Jeff J. Neil¹

¹Washington University, St. Louis, Missouri, USA; ²Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA

                  1342.    Three-Dimensional Magnetic Resonance Microscopy of Pulmonary Solitary Tumors in Transgenic Mice

Masaya Takahashi¹, Shigeto Kubo¹, Elena Levantini¹, Susumu Kobayashi¹, Olivier Kocher¹, Daniel G. Tenen¹

¹Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

                  1343.    Evaluation of Emphysema Severity and Progression in a Rabbit Model: A Comparison of Hyperpolarized
                                He-3 and Xe-129 ADC with Morphometry

Jaime Mata¹, Talissa Altes¹, ², Jing Cai¹, Kai Ruppert³, Wayne Mitzner⁴, James Brookeman¹, William Tobias¹,

James Wang¹, Gordon Cates¹, John Mugler III¹

¹University of Virginia, Charlottesville, Virginia, USA; ²Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; ³AMRIT, Sebastopol, California, USA; ⁴Johns Hopkins University, Baltimore, Maryland, USA

                  1344.    SPI Measurement of MR Signal and T2*  in Order to Characterize Emphysema Type Changes in a
                                Tight Skin Mouse Model

Lars E. Olsson¹, Maria Lindahl², Malin Palmér¹, Martina Kvist Reimer², Leif Hultin¹, Per-Ola Önnervik²,

Paul D. Hockings¹

¹AstraZeneca, Mölndal, Sweden; ²AstraZeneca, Lund, Sweden

                  1345.    Quantitative Assessment of Lung Volume Reduction Surgery Effectiveness in Improving
                                Functional Pulmonary Performance of Emphysematous Subjects - A Small Animal Model

Kiarash Emami¹, Masaru Ishii², Jianliang Zhu¹, John MacDuffie Woodburn¹, Jiangsheng Yu¹, Stephen J. Kadlecek¹, Vahid Vahdat¹, Benjamin M. Brainard¹, Michael E. Friscia¹, Joseph B. Shrager¹, Rahim R. Rizi¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA; ²Johns Hopkins University, Baltimore, Maryland, USA

                  1346.    Elastase Induced Emphysematous Development Assessed by Proton MRI in Spontaneously Breathing Rats

Harry Karmouty Quintana¹, ², Catherine Cannet¹, Stefan Zurbruegg¹, Lazzaro Mazzoni¹, John R. Fozard¹,

Clive P. Page², Nicolau Beckmann¹

¹Novartis Institutes for BioMedical Research, Basel, Switzerland; ²King's College London, London SE1 1UL, UK

                  1347.    ³He Imaging of Methacholine Challenge in Mouse Models of Asthma

Bastiaan Driehuys¹, Gary P. Cofer¹, Jim Pollaro¹, Julia K.L. Walker¹, David A. Schwartz², G A. Johnson¹

¹Duke University, Durham, North Carolina, USA; ²National Institute for Environmental Health Sciences, Research Triangle Park, North Carolina, USA

                  1348.    Characterisation of Lipopolysaccharide Induced Pulmonary Oedema in Rats by MRI

Sarah Hotee¹, ², Kumar Changani², Alan White², Kishore Bhakoo¹, Jimmy Bell¹

¹Imaging Sciences Department, Hammersmith, London, UK; ²GSK, The Frythe, Welwyn, UK

                  1349.    MR Imaging of Ex-Vivo Rat Lung with Acute Respiratory Distress Syndrome: Air-Inflation Fixation Method

Nobuyuki Kosaka¹, Hidemasa Uematsu¹, Hirohiko Kimura¹, Akinobu Kita², Harumi Itoh¹

¹University of Fukui, Fukui, Japan; ²University of Fukui Hospital, Fukui, Japan

                  1350.    Non-Invasive Monitoring of Lung Transplant Viability in a Small Animal Model Using MRI and PET

James H. Holmes¹, Rudolf K. Braun¹, Rafael L. O'Halloran¹, Zhuzai Xiang¹, Ronald L. Sorkness¹, Robert W. Pyzalski¹, Eric T. Peterson¹, Robert B. Love¹, Sean B. Fain¹

¹University of Madison-Wisconsin, Madison, Wisconsin, USA

Consoles and Interfaces

                  1351.    An Integrated MR Console / MR Physics Simulation System

Jonathan Sharp¹, Donghui Yin², Randy Tyson¹, Kan Lo¹, Boguslaw Tomanek¹

¹National Research Council of Canada, Calgary, Alberta, Canada; ²National Research Council of Canada, Winnipeg, Manitoba, Canada

                  1352.    A Scalable Prototype MR Console Using USB

Pascal Stang¹, Nathaniel Matter¹, Steve Conolly², John Pauly¹, Greig Scott¹

¹Stanford University, Stanford, California, USA; ²UC Berkeley, Berkeley, California, USA

                  1353.    Electrically Isolated Power Delivery for MRI Applications

Jan Gustav Werthen¹, Mort J. Cohen¹, Ta-Chung Wu¹, Seni Widjaja¹

¹JDS Uniphase, San Jose, California, USA

                  1354.    Surface MRI Using a Rastered Backprojection

Joseph P. Hornak¹, Christina L. Bray¹, Tyler Lucero¹, Allison Bright¹

¹RIT, Rochester, New York, USA

                  1355.    Integration of an External Motion Tracking System with the MR Scanner for Highly Accurate
                                Real-Time Prospective Motion Correction

Maxim Zaitsev¹, Christian Dold², Jürgen Hennig¹, Oliver Speck¹

¹University Hospital Freiburg, Freiburg, Germany; ²Fraunhofer Institute for Computer Graphics, Darmstadt, Germany


 

Multimodality and Novel Systems

                  1356.    Signal Optimization of Magnetic Field Pulses in Field-Cycled MRI

Jamu Krishna Alford¹, William Bradfield Handler¹, Timothy James Scholl¹, Blaine Alexander Chronik¹

¹University of Western Ontario, London, Ontario, Canada

                  1357.    Magnet Design and Construction for a Field-Cycled MRI/PET System

Kyle Michael Gilbert¹, William Bradfield Handler¹, Timothy James Scholl¹, Blaine Alexander Chronik¹

¹The University of Western Ontario, London, Ontario, Canada

                  1358.    Placing a PET Insert in the Bore of a 7T Magnet: Initial Study of the Interactions of the MRI System
                                with the PET Shielding

Bo Joseph Peng¹, Ciprian Catana¹, Jeff Walton¹, Simon R. Cherry¹, Jacob Willig-Onwuachi¹, ²

¹University of California, Davis, California, USA; ²UCDMC, Sacramento, California, USA

                  1359.    Evaluation of Mesh Photomultiplier Tube Operation for Dual Modality PET/MRI Systems

Hao Peng¹, William H. Handler¹, Kyle M. Gilbert¹, Tim J. Scholl¹, Peter J. Simpson¹, Blaine A. Chronik¹

¹University of Western Ontario, London, Ontario, Canada