MRI in Animal Models for Stroke and Traumatic Brain Injury

                  1451.    Early MRI Characterization of Cerebral Edema Following Diffuse Traumatic Brain Injury in Rat

Yohan van de Looij¹, ², Hana Lahrech¹, ², Gilles Francony¹, ², Olivier Carle¹, ², Régine Farion¹, ²,

Christoph Segebarth¹, ², Jean-François Payen¹, ²

¹INSERM U594, Grenoble, France; ²Univ Joseph Fourier, Grenoble, France

                  1452.    The Effect of Interleukin-1 on Local Brain Temperature During Focal Cerebral Ischemia in the Rat:
                                A ¹H Magnetic Resonance Spectroscopic Imaging Study

Adrian Robert Parry-Jones¹, Timo Liimatainen², Nancy Jane Rothwell¹, Risto Antero Kauppinen³, Olli H J Grohn²

¹University of Manchester, Manchester, UK; ²University of Kuopio, Kuopio, Finland; ³University of Birmingham, Birmingham, UK

                  1453.    Direct Evidence That Activating the Interleukin 1 Type I Receptor Enhances Ischemic Brain Damage

Jelena Lazovic¹, Anirban Basu², Raymond P. Rothstein³, Michael B. Smith⁴, Steven W. Levison³

¹California Institute of Technology, Pasadena, California, USA; ²National Brain Research Center, Gurgaon, India; ³University of Medicine and Dentistry, East Orange, New Jersey, USA; ⁴The Pennsylvania State University, Hershey, Pennsylvania, USA

                  1454.    In Vivo Measurement of Blood Flow After Traumatic Brain Injury in Rats Using Susceptibility Weighted Imaging

Yimin Shen¹, Jiani Hu¹, Christian W. Kreipke¹, Theodor Petrov¹, E Mark Haacke¹, ²

¹Wayne State University School of Medicine, Detroit, Michigan, USA; ²MRI Institute of Biomedical Research, Detroit, Michigan, USA

                  1455.    Delayed Thalamic Damage After Stroke: Discriminator for Recovery Success from Functional
                                Loss in the Cortex of the Rat

Carlos Justicia¹, Pedro Ramos-Cabrer¹, Ralph Weber¹, Dirk Wiedermann¹, Cordula Strecker¹, Christiane Sprenger¹, Mathias Hoehn¹

¹Max-Planck-Institute for Neurological Research, Cologne, Germany

                  1456.    The Response of the Fetal Brain to Antenatal Hypoxia-Ischemia Detected by Diffusion-Weighted Imaging

Alexander Drobyshevsky¹, Matthew Derrick¹, Alice M. Wyrwicz¹, Pottumarthi Prasad¹, Xinhai Ji¹,

Ila Englof², Sidhartha Tan¹

¹Evanston Northwestern Healthcare, Evanston, Illinois, USA; ²Evanston Northwestern Healthcare, Evanston,, Illinois, USA

                  1457.    Unilateral Common Carotid Artery Occlusion: A Transient Ischemia Model Well Suited to MR Studies

Jeremy Joseph Flint¹, Stephen J. Blackband¹, ², Peter E. Thelwall¹

¹University of Florida, Gainesville, Florida, USA; ²National High Magnetic Field Laboratory, Tallahassee, Florida, USA

                  1458.    MRI Investigation of Combination Treatment of Embolic Stroke in Rat with Rt-PA and Atorvastatin

Guangliang Ding¹, Quan Jiang¹, Lian Li¹, Li Zhang¹, Zheng Gang Zhang¹, Swayamprava Panda¹, James R. Ewing¹, Michael Chopp¹

¹Henry Ford Health Sciences Center, Detroit, Michigan, USA

                  1459.    Spatiotemporal Pattern of USPIO Enhancement in Experimental Stroke Lesions Depends
                                on the Type of Ischemic Injury: A 9,4 T MRI Study

Michael Schroeter¹, Ana M. Oros-Peusquens², Marko Irkens², Avdo Celik², Andreas Saleh¹, Nadim J. Shah²,

Sebastian Jander¹

¹Heinrich Heine-University, Duesseldorf, Germany; ²Research Centre Juelich, Juelich, Germany

                  1460.    MR Imaging of Rat Monocytes Homing Towards an Area of Cerebral Infarction

Raoul David Oude Engberink¹, Erik I. Hoff², Susanne M. van der Pol³, Erwin L. Blezer¹, Helga E. de Vries³

¹University Medical Center Utrecht, Utrecht, Netherlands; ²Department of Neurology, Maastricht, Netherlands; ³VU Medical Center, Amsterdam, Netherlands

                  1461.    fMRI of Delayed Albumin Treatment During Stroke Recovery in Rats: Implication for
                                Fast Neuronal Habituation in Recovering Brains

Young Ro Kim¹, Mauritz P.A. van Meer¹, Joseph B. Mandeville¹, Emiri Tejima², George Dai¹, Kamil Topalkara³, Jianhua Qui³, Rick M. Dijkhuizen⁴, Mike A. Moskowitz³, Eng H. Lo², Bruce R. Rosen¹

¹Athinoula Martinos Center for Biomedical Imaging/ Massachusetts General Hospital, Charlestown, Massachusetts, USA; ²Neuroprotection Research laboratory/ Massachusetts General Hospital, Charlestown, Massachusetts, USA; ³Stroke and Neurovascular Regulation Laboratory/  Massachusetts General Hospital, Charlestown, Massachusetts, USA; ⁴Image Sciences Institute, University Medical Center Utrecht, The Netherlands, Charlestown, Massachusetts, USA

                  1462.    Dynamic Tissue Fates Tracking in Acute and Sub-Acute Phase of a Transient Occlusion Rat Model

Qiang Shen¹, Hongxia Ren¹, Jürgen Bardutzky², Marc Fisher³, Timothy Q. Duong¹

¹Emory Unviersity, Atlanta, Georgia, USA; ²University of Heidelberg, Heidelberg, Germany; ³The University of Massachusetts Medical School, Worcester, Massachusetts, USA

                  1463.    Time Course of Water Diffusivity in the Rat Brain After Global Ischemia

Ivan Vorisek¹, ², Helena Neprasova¹, Miroslava Anderova¹, Daniel Jirak³, Milan Hajek³, Alexandr Chvatal¹,

Eva Sykova¹, ²

¹Institute of Experimental Medicine ASCR, Prague, Czech Republic, Czech Republic; ²Charles University, 2nd Medical Faculty, Prague, Prague, Czech Republic, Czech Republic; ³Institute for Clinical and Experimental Medicine, Prague, Czech Republic, Czech Republic

                  1464.    Brain Tissue Regeneration Following Activation of Endogenous Stem Cells in Animal Model of Stroke

Nancy J. Lobaugh¹, Anna Erlandsson², Hai-Ling Margaret Cheng³, Voytek Gretka¹, Cindi Morshead², Greg J. Stanisz¹

¹Sunnybrook & Womens' CHSC, Toronto, ON, Canada; ²University of Toronto, Toronto, ON, Canada; ³Hospital for Sick Children, Toronto, ON, Canada

                  1465.    Application of a Rat Stroke Model for Preclinical Evaluation of Anti-Stroke Drugs: Noninvasive
                                Monitoring with Comprehensive Magnetic Resonance Imaging

Feng Chen¹, Yicheng Ni¹, Nobuo Nagai², Yasuhiro Suzuki², Desire Collen², Guy Marchal²

¹Catholic University of Leuven, Leuven, Flamms Brabant, Belgium; ²Catholic University of Leuven, Leuven, Flaams Brabant, Belgium

                  1466.    Correlation of Proton Transfer Ratio and Intracellular PH in Acute Ischaemia

Kimmo T. Jokivarsi¹, Heidi I. Gröhn¹, Olli H. Gröhn¹, Risto A. Kauppinen²

¹A.I. Virtanen Institute for Molecular Sciences, University of Kuopio, Kuopio, Finland; ²School of Sport and Exercise Sciences, University of Birmingham, Birmingham, UK

                  1467.    Comparison of Cerebral Blood Flow Estimates in the Ischemic Area of Rat Brain Obtained with
                                Dynamic Susceptibility Contrast and Continuous Arterial Spin Labeling

Ryo Kagaya¹, ², Kazuhiro Nakamura², ³, Yasushi Kondoh², Masanobu Ibaraki², Jeff Kershaw², ³, Guoyue Chen¹,

 Iwao Kanno²

¹Akita Pref Univ, Ugo-Honjoh, Japan; ²Akita Res Inst of Brain and Vessels, Akita, Japan; ³Akita Industry Promotion Found, Akita, Japan


 

Ulrike Wedegärtner¹, Hendrik Kooijman², Andrew N. Priest¹, Mikhail Tchirikov¹, Hobe J. Schröder¹, Gerhard Adam¹

¹University Hospital Hamburg-Eppendorf, Hamburg, Germany; ²Philips Medical Systems, Hamburg, Germany

                  1469.    Timecourse of Early CBF Changes After Controlled Cortical Impact in Mice

Lesley M. Foley¹, T Kevin Hitchens¹, Patrick M. Kochanek², John A. Melick², Chien Ho¹

¹Carnegie Mellon University, Pittsburgh, Pennsylvania, USA; ²University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

                  1470.    Post-Ischaemic Gene Therapy for Stroke: An MRI Study

Romina Aron Badin¹, Mark F. Lythgoe¹, Martin D. King¹, David S. Latchman¹, David G. Gadian¹

¹Institute of Child Health, University College London, London, UK

                  1471.    Temporal and Spatial Evolution of MR Derived Cerebral Metabolic Rate of Oxygen Utilization Index
                                in Acute Middle Cerebral Artery Occlusion Stroke Rats

Hongyu An¹, Yasheng Chen¹, Liansheng Chang¹, Weili Lin¹

¹University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

                  1472.    Cerebral Edema Induced by Synchrotron Microbeam Radiation Therapy in the Healthy Mouse Brain.
                                Characterization by Means of Diffusion Tensor Imaging

Yohan van de Looij¹, Raphaël Serduc¹, Gilles Francony¹, Olivier Verdonck¹, Elke Brauer², Boudewijn van der Sanden¹, Christoph Segebarth¹, Chantal Remy¹, Hana Lahrech¹

¹UJF/INSERM U594, Grenoble, France; ²European Synchrotron Radiation Facility, Grenoble, France

                  1473.    High Resolution Sodium Imaging of Rat and Mouse Models of Stroke at 17.6 T

Thomas Neuberger¹, ², Andrew Webb¹, ²

¹Penn State University, University Park, Pennsylvania, USA; ²University of Würzburg, Würzburg, Germany


 

Animal Brain  MRS: 1H MRS

                  1474.    Effect of Iron Deficiency on Developing Rat Striatum

Ivan Tkac¹, Kay L. Ward¹, Barbara Felt², Betsy Lozoff², Michael K. Georgieff¹, Raghavendra Rao¹

¹University of Minnesota, Minneapolis, Minnesota, USA; ²University of Michigan, Ann Arbor, Michigan, USA

                  1475.    Water and Metabolite Proton T1 and T2 Relaxation in Rat Brain In Vivo

Robin A. de Graaf¹, Peter B. Brown¹, Scott McIntyre¹, Terence W. Nixon¹, Kevin L. Behar¹, Douglas L. Rothman¹

¹Yale University, New Haven, Connecticut, USA

                  1476.    Monitoring De- And Re- Myelination MR Spectroscopy Surrogate Markers in the Mouse Brain at 9.4 T

Wafaa Zaaraoui¹, ², Mathilde Deloire³, Michel Merle², Gerard Raffard², Marc Biran², Maria Inglese¹, Klaus G. Petry³, Jean-Michel Franconi², Oded Gonen¹, Vincent Dousset³

¹New York University, New York, New York, USA; ²RMSB UMR 5536, Bordeaux, France; ³EA2966 Universite Victor Segalen Bordeaux, Bordeaux, France

                  1477.    MR Studies of Aging in the Hippocampus of the FBNF1 Rat Show Correlations with
                                Behavioral and Structural Degeneration

Ira Driscoll¹, ², Robert S. Sutherland², Boguslaw Tomanek³, Jeff F. Dunn³, William M. Brooks⁴

¹National Institute on Aging, Baltimore, Maryland, USA; ²University of Lethbridge, Lethbridge, Alberta, Canada; ³University of Calgary, Calgary, Alberta, Canada; ⁴University of Kansas Medical Center, Kansas City, Kansas, USA

                  1478.    In Vivo Observation of Hypernatremia During Sodium Lactate Infusion

Su Xu¹, Wenjun Zhu¹, Jun Shen¹

¹National Institute of Mental Health, Bethesda, Maryland, USA

                  1479.    Acute Administration of Nicotine Reduced Myo-Inositol and GABA Levels in Nucleus Accumbens in Rats

Serguei Liachenko¹, Robert Durham¹, Lori Badura², Peter Snyder²

¹Pfizer, Inc., Ann Arbor, Michigan, USA; ²Pfizer, Inc., Groton, Connecticut, USA

                  1480.    Effects of Chronic Morphine Treatment on Metabolism of Glutamate and GABA in Rat Prefrontal Cortex
                                Studied by Ex Vivo High Resolution ¹H NMR Spectroscopy

Hongchang Gao¹, Yun Xiang¹, ², Hang Zhu¹, Ninglei Sun³, Yuanye Ma³, Maili Liu¹, Hao Lei¹

¹Wuhan Institute of Physics & Mathematics, Chinese Academy of Sciences, Wuhan, Hubei, People’s Republic of China; ²Jianghan University, Wuhan, Hubei, People’s Republic of China; ³Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, People’s Republic of China

                  1481.    Morphological and Metabolic Changes in the Brain of 6-Hydroxydopamine Treated Rats Observed
                                by MRI and In Vivo ¹H MRS

Fang Fang¹, Yuanyi Ma², Shuzhen Kong², Min He², Hao Lei¹

¹Wuhan Institute of Physics & Mathematics, Chinese Academy of Sciences, Wuhan, Hubei, People’s Republic of China; ²Kunming Medical College, Kunming, Yunnan, People’s Republic of China

                  1482.    Methylphenidate Administration During Adolescence Produces Long-Term Effects in Adult Rat Brain:
                                A 1H MRS In Vivo Study

Rossella Canese¹, Walter Adriani¹, Franca Podo¹, Giovanni Laviola¹

¹Istituto Superiore di Sanità, Rome, Italy

                  1483.    Metabolic Responses in Kanic Acid Induced Lesion in Rat

Hui Mao¹, Donna Toufexis², Xiaoxia Wang¹, Shaoxiong Wu², Agnes Lacreuse²

¹Emory University School of Medicine, Atlanta, Georgia, USA; ²Emory University, Atlanta, Georgia, USA

                  1484.    Creatine Uptake Kinetics in Brain and Skeletal Muscle of GAMT Deficient Knockout Mice

Hermien Elise Kan¹, Esther Meeuwissen¹, Andor Veltien¹, Dirk Isbrandt², Arend Heerschap¹

¹Radboud University Nijmegen Medical Center, Nijmegen, Netherlands; ²University of Hamburg, Hamburg, Germany

                  1485.    MRI and MRS Study of a Transgenic Mouse Model of D1 Dopamine Receptor Positive Striatal Cell Depletion

Ke Fang¹, Ilsa Gantois¹, Hong Xin Wang¹, Qi Zhu Wu¹, Qing Yang¹, John Drago¹, Gary Francis Egan¹

¹Howard Flory Institute, Melbourne, Vic, Australia

                  1486.    Metabolic Interactions Between Glutamatergic and Dopaminergic Neurotransmiter Systems
                                Are Mediated Through D1, But Not D2, Dopamine Receptors

Tiago B. Rodrigues¹, ², Ana B. Martin³, Patricia Sanchéz¹, Sebastián Cerdán¹, Rosario Moratalla³

¹Inst. Inv. Biomedicas "Alberto Sols", Madrid, Spain; ²University of Coimbra, Coimbra, Portugal; ³Inst. Cajal, Madrid, Spain

                  1487.    Aggregation-Induced Reduction in T₂ Relaxation Time of MR Visible Lipids Observed in Ischemic
                                Rat Brain

Li Wei¹, Hao Lei¹

¹Wuhan Institute of Physics & Mathematics, Chinese Academy of Sciences, Wuhan, Hubei, People’s Republic of China

                  1488.    Identification of Neural Stem Cells in Rat Brain Using Their Specific Magnetic Resonance
                                Spectroscopy Signature

Raphael D. Hazel¹, Louis N. Manganas², Xueying Zhang³, Mei Yu⁴, Petar M. Djuric³, Helene Benveniste³,

Mark E. Wagshul³, Mirjana Maletic-Savatic, ²³

¹Stony Brook University, Stony Brook, New Yory, USA; ²Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA; ³Stony Brook University, Stony Brook, New York, USA; ⁴Brookhaven National Laboratory, Brookhaven, New York, USA

                  1489.    The Effect of Paramagnetic Manganese Cations on ¹H MR Spectroscopy of the Brain

Kathrine Skak Madsen¹, ², David Alberg Holm¹, ³, Lise Vejby Søgaard¹, Gert Rene Christoffersen², Ian John Rowland¹

¹Copenhagen University Hospital, Hvidovre, Denmark; ²University of Copenhagen, Copenhagen, Denmark; ³Technical University of Denmark, Copenhagen, Denmark

                  1490.    Measurement of T₁ Relaxation Times of Major Metabolites in the Mouse Brain at 11.7 and 17.6 Tesla
                                Using Voxel-Localized Proton Magnetic Resonance Spectroscopy

Thomas Neuberger¹, ², Andrew Webb¹, ², Cornelius Faber², Volker Christian Behr², Stefan Neubauer³,

Jürgen E. Schneider³

¹Huck Institute Magnetic Resonance Centre, University Park, Pennsylvania, USA; ²University of Würzburg, Würzburg, Germany; ³University of Oxford, Oxford, UK

                  1491.    Quantitative MR Spectroscopic Evaluation of Radiation-Induced Brain Injury in a Rat Model

Todd Atwood¹, Mike Robbins¹, Jian-Ming Zhu¹

¹Wake Forest University School of Medicine, Winston Salem, North Carolina, USA

                  1492.    Quantitative 1H MRS in the Rat Hippocampus After Global Ischemia

Daniel Jirak¹, ², Ivan Vorisek³, Eva Sykova⁴, Milan Hajek¹, ²

¹IKEM, Prague 4, Czech Republic; ²Charles University, 2nd Faculty of Medicine, Prague, Czech Republic; ³Institute of Experimental Medicine,, Prague, Czech Republic; ⁴Institute of Experimental Medicine, Prague, Czech Republic

                  1493.    In Vivo Brain NMR Spectroscopy of Alpha-Mannosidosis in a Feline Model

Sergey Magnitsky¹, Charles H. Vite², Stephen Pickup¹, David Aleman², John H. Wolfe², Harish Poptani³

¹The University of Pennsylvania, Philadelphia, Pennsylvania, USA; ²University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA; ³The University of Pennsylvania,, Philadelphia, Pennsylvania, USA

                  1494.    ¹HMRS in a Monkey Model of AIDS and Opiates

Christine Carol Cloak¹, Linda Chang¹, Shawn O'Neil², Thomas M. Ernst¹, Dan Anderson³, Robert M. Donahoe⁴

¹University of Hawaii, JABSOM, Honolulu, Hawaii, USA; ²Harvard Medical School, Southborough, Massachusetts, USA; ³Emory University, Atlanta, Georgia, USA; ⁴University of Utah, School of Medicine, Salt Lake City, Utah, USA

                  1495.    Genotype Specific Alterations Detected in the Neurochemical Profiles of Aged Transgenic
                                Mouse Models of Alzheimer's Disease

Malgorzata Marjanska¹, Geoffrey L. Curran², Thomas M. Wengenack², Pierre-Gilles Henry¹, Robin L. Bliss¹,

Joseph F. Poduslo², Clifford R. Jack, Jr. ², Kamil Ugurbil¹, Michael Garwood¹

¹University of Minnesota, Minneapolis, Minnesota, USA; ²Mayo Clinic College of Medicine, Rochester, Minnesota, USA

                  1496.    The Pathophysiogical Basis of Brain Swelling of Grey vs. White Matter in Acute Liver Failure
                                Are Different: Lessons from a Study Using MARS

Claudia Zwingmann¹, ², Chris Rose¹, Surajit Sen³, Nathan Davies⁴, Roger Frank Butterworth¹, Dieter Leibfritz²,

Lars Marius Ytrebo⁵, Arthur Revhaug⁵, Rajiv Jalan⁶

¹Hospital Saint-Luc, Montreal, Quebec, Canada; ²University of Bremen, Bremen, Germany; ³State University of New York, Buffalo, New York, USA; ⁴University College London, London, UK; ⁵University Hospital of Northern Norway, Tromso, Norway; ⁶Royal Free & University College Medical School, London, UK

                  1497.    Effect of Blood Flow on Brain Temperature Distribution

Mingming Zhu¹, ², Joseph J. H. Ackerman¹, ², Alexander L. Sukstanskii², Dmitriy A. Yablonskiy, ¹²

¹Washington University, St. Louis, Missouri, USA; ²Washington University School of Medicine, St. Louis, Missouri, USA


 

Brain: Miscellaneous MRI

                  1498.    The Association of Low-Dosage Sex Hormone Replacement Therapy and the Aging Brain Using 3.0T
                                MR Scanner

Hu Ling¹, Jin Zheng Yu¹, Feng Feng¹, Ge Qinsheng¹, Li Mingli¹

¹Peking Union Medical College Hospital, Beijing, People’s Republic of China

                  1499.    Early Experience from the Application of a Noninvasive MRI-Based Measurement of
                                Intracranial Pressure in Hydrocephalus

Noam Alperin¹, Josh Niebruegge¹, Terry Lichtor², Roberta Glick²

¹University of Illinois at Chicago, Chicago, Illinois, USA; ²Cook County Hospital, Chicago, Illinois, USA

                  1500.    Neuroprotective Effect of Long-Term Low Dose Hormone Replacement Therapy on
                                Postmenopausal Women Brain Hippocampus

Hu Ling¹, Yue Yun², Zuo Pingping², Jin Zheng Yu¹, Feng Feng¹, Ge Qinsheng¹

¹Peking Union Medical College Hospital, Beijing, People’s Republic of China; ²Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical Coll, Beijing, People’s Republic of China

                  1501.    Will Piecewise Continuous Echo Spacing Adversely Affect the T₂ Distribution?

Thorarin Albert Bjarnason¹

¹University of Calgary, Calgary, AB, Canada

                  1502.    Magic Echo Imaging of the Brain at 1.5 T

Walter R.T. Witschey II¹, Brian K. Bronzo¹, Arijitt Borthakur¹, Ravinder Reddy¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA

                  1503.    PET Restoration by Maximization of MRI-PET Mutual Information

Yong Chu¹, Min-Ying Su¹, Mark Mandelkern¹, Orhan Nalcioglu¹

¹University of California, Irvine, California, USA

                  1504.    Variability of Automated Shape Analyses of Fixed Brain Mouse MRI

Jason Lerch¹, Shoshana Tsatskis¹, John Sled¹, Natasa Kovacevic¹, R. Mark Henkelman¹

¹Mouse Imaging Centre, Toronto, Ontario, Canada

                  1505.    Pre-Processing Strategies to Improve Longitudinal MRI Repeatability

Kelvin Wong¹, ², Xiaoyin Xu², Geoffrey Young², Stephen Wong¹, ²

¹Harvard Medical School, Boston, Massachusetts, USA; ²Brigham and Women's Hospital, Boston, Massachusetts, USA

                  1506.    Biocompatibility of Sapphire and Borosilicate Glass for Neural Prosthesis Using MRI and Histopathology

Kaushik Saranath Parthasarathy¹, Yimin Shen¹, Kelley Brabant¹, Jie Li¹, Yu Cheng¹, Gregory William Auner¹,

James Pat McAllister II¹, Ewart Mark Haacke¹

¹Wayne State University, Detroit, Michigan, USA

                  1507.    Using MRI Images for Determination of Near-Infrared Regions of Sensitivity in Rodent Brain

Hamid Dehghani¹, Jeff Frank Dunn²

¹University of Exeter, Exeter, UK; ²University of Calgary, Calgary, AB, Canada

                  1508.    SWI Filtered Phase Images Demonstrate That Tissue Iron in the Midbrain Correlates
                                with Local Capillary Density

Ewart Mark Haacke, Ph.D. ¹, ², Elena Svilenova Manova¹, Muhammed Ayaz², Asadullah Khan², Daniel K. Kido³,

 Wolff Kirsch³

¹Wayne State University, Detroit, Michigan, USA; ²The MRI Institute for Biomedical Research, Detroit, Michigan, USA; ³Loma Linda University, Loma Linda, California, USA

                  1509.    Voxel-Based Morphometry Analysis of Structural Gray Matter Volume Variations Across
                                Idiopathic and Cryptogenic Epilepsy Syndromes

Heath Pardoe¹, Gaby S. Pell¹, Anne T. Berg², David F. Abbott¹, Graeme D. Jackson¹

¹Brain Research Institute, Melbourne, Victoria, Australia; ²Northern Illinois University, DeKalb, Illinois, USA

                  1510.    Cerebrospinal Fluid Pulsatility Model and Its Validation

Jieun Kim¹, Neil A. Thacker¹, Paul A. Bromiley¹, Stephen J. Payne², Alan Jackson¹

¹University of Manchester, Manchester, UK; ²University of Oxford, Oxford, UK

                  1511.    Perfusion Weighted MR in NPSLE

Bart Jeroen Emmer¹, M J. van Osch¹, D van As¹, O Wu², G M. Steup-Beekman¹, S C. Steens¹, T W. Huizinga¹,

M A. van Buchem¹, J van der Grond¹

¹Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands; ²Massachusetts General Hospital, Charlestown, Massachusetts, USA

                  1512.    Contrast-Enhanced First Pass Perfusion MR Imaging in Patients with Subclinical Hepatic Encephalopathy

Li Tao¹, Ma Lin¹, Li Tao¹

¹PLA General Hospital, Beijing, People’s Republic of China China

                  1513.    Central Pontine Myelinolysis After Liver Transplantation: MR Diffusion, Spectroscopy, and Perfusion Findings

Yong Guo¹, Jinhua Hu², Wei Lin¹, Kuihong Zheng¹

¹General navy Hospital, Beijing, People’s Republic of China; ²302 Hospital of PLA, Beijing, People’s Republic of China


 

Eyes, Glands, and Neck

                  1514.    Characteristic MRI Findings of Metastatic Neuroblastomas and Chloromas in the Orbit in Children

Junfang Xian¹, Zhenchang Wang¹, Liyan He¹

¹Beijing Tongren Hospital, Beijing, People’s Republic of China

                  1515.    Assessment of Orbital Masses Using Dynamic Contrast-Enhanced MR Imaging

Liyan He¹, Jun Fang Xian¹, Zhen Chang Wang¹, Zhong Lin Liu¹, Fei Yan¹, Yan Tao Niu¹, Bo Zhao¹

¹Beijing tongren Hospital, Beijing, People’s Republic of China

                  1516.    Study of Ocular Drug Delivery Using Contrast-Enhanced Magnetic Resonance Imaging

Stephanie Kim¹, ², Craig J. Galban¹, Michael R. Robinson¹, Karl G. Csaky¹, Martin J. Lizak¹, Ginger Tansey¹,

Nam Sun Wang², Robert J. Lutz¹

¹NIH, Bethesda, Maryland, USA; ²University of Maryland, College Park, Maryland, US

                  1517.    In Vivo Echo Planar Diffusion Tensor Imaging of the Optic Nerve in Rats

Marte Thuen¹, Anders Kristoffersen², Torgil Riise Vandberg², Trond Erling Singstad², Olav Haraldseth¹,

Christian Brekken¹

¹Norwegian University for Science and Technology, Trondheim, Norway; ²St. Olavs Hospital HF, Trondheim, Norway

                  1518.    First Report of Diffusion Tensor Imaging of the Murine Eye

Saurav Chandra¹, Kyle Padgett¹, John R. Forder²

¹University of Florida, Gainesville, Florida, USA; ²McKnight Brain Institute, University of Florida, Gainesville, Florida, USA

                  1519.    Does the Use of Passive Occlusion Combined with a Sialogogue Improve MR Sialography ?

Jo Ann Hugill¹, Kieren Grant Hollingsworth², Evis Sala², David J. Lomas²

¹Addenbrookes Hospital, Cambridge, Cambridgeshire, UK; ²University of Cambridge, Cambridge, Cambridgeshire, UK

                  1520.    Differentiating Squamous Cell Carcinoma from Other Types of Tumors in the Head and Neck Region by ¹H MRS

Tedros Bezabeh¹, Olva Odlum¹, ², Richard Nason¹, ³, Paul Kerr³, Donna Sutherland³, Rakesh Patel¹, Ian C.P. Smith¹

¹National Research Council, Institute for Biodiagnostics, Winnipeg, Manitoba, Canada; ²University of Manitoba, Winnipeg, Manitoba, Canada; ³CancerCare Manitoba, Winnipeg, Manitoba, Canada

                  1521.    Dynamic Magnetic Resonance Imaging of Swallowing Using a Synchronized Sampling Method

Yasutoshi Honda¹, Yoshinobu Yanagi¹, Noriko Kawai¹, Kanji Kishi¹, Dang Jianwu²

¹Graduate school of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama-shi, Okayama, Japan; ²Japan Advanced Institute of Science and Technology, Nomi, Ishikawa, Japan

                  1522.    Apparent Diffusion Coefficient in Malignant Lymphoma and Carcinoma Involving Cavernous Sinus
                                Evaluated by Line Scan Diffusion-Weighted Imaging

Masayuki Maeda¹, Hajime Sakuma¹, Kan Takeda¹

¹Mie University School of Medicine, Tsu, Mie, Japan

                  1523.    Dynamic MRI of Vocal Cords Using Carotid Phased Array Coils

Marc Uwe Schlamann¹, Stefan Maderwald¹, Goetz Lehnerdt¹, Isabel Wanke¹, Roya Jeyrani¹, Susanne Ladd¹

¹University of Essen Medical School, Essen, Germany

                  1524.    Characterization of a MRI Compatible Head / Neck Immobilization and Repositioning Device for
                                Longitudinal Studies of the Carotid Artery

Emilee S. Minalga¹, J. Rock Hadley¹, Dennis L. Parker¹

¹University of Utah, Salt Lake City, Utah, USA

                  1525.    Technique for Acquiring MR Images of CSF Flow During a Valsalva Maneuver

Andrew L. Wentland¹, Oliver Wieben¹, Charles A. Mistretta¹, Frank R. Korosec¹, Victor M. Haughton¹

¹University of Wisconsin, Madison, Wisconsin, USA

                  1526.    Evaluation of Aneurysm Hemodynamics Using Phase Contrast Vastly Undersampled Isotropic Projection Imaging

Kevin Michael Johnson¹, Roham Moftakhar¹, Beverly Aagaard¹, Chuck Mistretta¹

¹University of Wisconsin-Madison, Madison, Wisconsin, USA

                  1527.    Anatomic Imaging of the Soft Palate During Phonation as an Aid in Cleft Palate Presurgical Planning

James S. Hyde¹, David A. Soltysik¹, Andrzej Jesmanowicz¹, Arun K. Gosain²

¹Medical College of Wisconsin, Milwaukee, Wisconsin, USA; ²Children's Hospital of Wisconsin, Milwaukee, Wisconsin, USA

                  1528.    Dynamic MRI of the Orbit

Marco Piccirelli¹, ², Roger Luechinger¹, Oliver Bergamin², Michaela Soellinger¹, Andrea Rutz¹, Christof Baltes¹,

Peter Boesiger¹

¹Swiss Federal Institute of Technology & University of Zürich, Zürich, ZH, Switzerland; ²University Hospital of Zürich, Zürich, ZH, Switzerland


 

Cerebral Blood Flow and Dynamic Contrast Perfusion

                  1529.    Relaxivity of Blood Pool Contrast Agent Depends on the Host Tissue as Suggested by Semianalytical Simulations

Birgitte Fuglsang Jensen¹, Leif Østergaard¹, Valerij G. Kiselev²

¹Aarhus University Hospital, Aarhus, Denmark, Denmark; ²University Hospital Freiburg, Freiburg, Germany, Germany

                  1530.    Intercompartmental Water Exchange Effects in DCE MRI

Xin Li¹, William Rooney¹, Charles Springer¹

¹Oregon Health & Science University, Portland, Oregon, USA

                  1531.    Investigations on the Non-Mono Exponential Signal Decay in Presence of a Single Vessel; Simulations,
                                Phantom and In Vivo Measurements

Jan Sedlacik¹, Alexander Rauscher¹, Jürgen Rainer Reichenbach¹

¹Friedrich Schiller Universität, Jena, Thüringen, Germany

                  1532.    A Re-Examination of the Impact of Dispersion on Quantitative Cerebral Blood Flow Measurements

Linda Ko¹, Marina Salluzzi¹, Richard Frayne¹, Michael Smith¹

¹University of Calgary, Calgary, Alberta, Canada

                  1533.    The Effects of Background Micro-Circulation in the AIF Measured from DSC MRI of the Brain

Zhiyue J. Wang¹, ², Robert J. Thornton¹, ², Jeremy Y. Jones¹, ²

¹Baylor College of Medicine, Houston, Texas, USA; ²Texas Children's Hospital, Houston, Texas, USA

                  1534.    Automated Selection of Arterial Input Function (AIF) Pixels in DCE-MRI

Andreas Pohlmann¹, Katja Oberholzer¹, Wolfgang G. Schreiber¹

¹Johannes Gutenberg University Medical School, Mainz, Germany

                  1535.    Automated Computation of the Vascular Input Function for Dynamic Contrast-Enhanced MRI of the Brain

Sandeep Narendra Gupta¹, John A. Butman²

¹GE Healthcare, Hanover, Maryland, USA; ²Clinical Center, NIH, Bethesda, Maryland, USA

                  1536.    Visualization of Distinct Collateral Flow Territories in Patients with Symptomatic Carotid Artery Occlusion

Peter Jan van Laar¹, Jeroen Hendrikse¹, Willem Mali¹, Karin Klijn¹, Jaap Kappelle¹, Matthias van Osch²,

Jeroen van der Grond²

¹University Medical Center, Utrecht, Netherlands; ²Leiden University Medical Center, Leiden, Netherlands

                  1537.    Improved Contrast in Dynamic Contrast Enhanced MRI by Combining Complex In-Phase and
                                Opposed-Phase Data: Simulations and Phantom Experiment

Karl-Heinz Herrmann¹, Alexander Rauscher¹, Werner A. Kaiser¹, Jürgen R. Reichenbach¹

¹IDIR, Friedrich-Schiller University, Jena, Germany

                  1538.    Voxel-Wise Exact T1 Estimation for Accurate Quantitation of Perfusion Indices Using Fast
                                3D-SPGR in Intracranial Mass Lesion

RKS Rathore¹, Anup Singh¹, RK Gupta², P Mohan², Md Haris², Getaneh Bayu¹, Divya KS Rathore¹, Ankur Purwar¹, Manoj K. Sarma¹

¹Indian Institute of Technology, Kanpur, UP, India; ²Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, UP, India

                  1539.    Extraction of the Contribution of the First Bolus Passage to the Signal in Dynamic Perfusion Measurements

Peter Gall¹, Oliver Speck¹, Ralph Strecker¹, Valerij G. Kiselev¹

¹University Hospital Freiburg, Freiburg, Germany

                  1540.    Accurate Dynamic Susceptibility Contrast MR Perfusion Quantification Using Spatiotemporal
                                Noise Filtering Algorithms

Jayme C. Kosior¹, ², Richard Frayne, ¹²

¹University of Calgary, Calgary, Alberta, Canada; ²Foothills Medical Centre, Calgary Health Region, Calgary, Alberta, Canada

                  1541.    Adaptive SVD Thresholding is Shown to Be More Appropriate for Partial Brain Scans (TR = 1 S)
                                Rather Than Full Brain Scans (TR = 2 S)

Michael Smith¹, Marina Salluzzi¹, Richard Frayne¹

¹University of Calgary, Calgary, Alberta, Canada

                  1542.    Thresholding Artefacts in SSVD and OSVD Deconvolution

Louise Gyldensted¹, Kim Mouridsen¹, Leif Østergaard¹

¹Aarhus University Hospital, Aarhus, Denmark

                  1543.    Estimation of Red Blood Cell Flow Using Microbubbles as a Contrast Agent for DSC-MRI

Christopher Chad Quarles¹, Ronald R. Price¹, John Christopher Gore¹

¹Vanderbilt University, Nashville, Tennessee, USA

                  1544.    Quantitative Cerebral Blood Flow Measurement at 3.0T : The Comparison of GE-EPI and SE-EPI

Wanyong Shin¹, Ty Allen Cashen¹, Jeffrey Miller², Matthew T. Walker², Medhi Rohany², Timothy J. Carroll¹, ²

¹Northwestern University, Chicago, Illinois, USA; ²Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

                  1545.    High Resolution Dynamic-Susceptibility Contrast Perfusion Imaging Using Multi-Echo Parallel EPI

Thies Halvor Jochimsen¹, Rexford Newbould¹, Stefan Skare¹, David B. Clayton¹, Michael E. Moseley¹,

Roland Bammer¹

¹Stanford University, Palo Alto, California, USA

                  1546.    T2* Perfusion Imaging at 7.0 Tesla Using 3D PRESTO: Initial Results

Christoph A. Manka¹, Christiane K. Kuhl¹, Lukas Scheef¹, Carsten Meyer¹, Michael R. Thompson², John Duraj²,

Frank Gerardus Hoogenraad³, Jürgen Gieseke⁴, Hans H. Schild¹

¹University of Bonn, Bonn, Germany; ²Philips Medical Systems, Cleveland, Ohio, USA; ³Philips Medical Systems, Best, Netherlands; ⁴Philips Medical Systems, Bonn, NRW, Germany

                  1547.    The Age Dependence of QCBF Measure with the Bookend Technique

Timothy J. Carroll¹, Wanyong Shin², Hyun Jeong¹, Matthew Walker¹, Ali Shaibani¹, Medhi Rohany¹, James Carr¹,

Ty Cashen¹

¹Northwestern University, Chicago, Illinois, USA; ²Northwestern, Chicago, Illinois, USA

                  1548.    Variability in QCBF Obtained from Deconvolution-Based Perfusion-Weighted MR Techniques

Daniel James Niven¹, Jayme C. Kosior¹, ², Peter J. Dickhoff³, Imanuel Dzialowski⁴, ⁵, Suresh Subramaniam⁴, ⁵

 Andrew M. Demchuk⁴, ⁵, Richard Frayne¹, ⁶

¹Seaman Family MR Centre, Foothills Medical Centre, Calgary Health Region, Calgary, Alberta, Canada; ²Electrical and Computer Engineering, University of Calgary, Calgary, Alberta, Canada; ³Diagnostic Imaging, Rockyview General Hospital, Calgary Health Region, Calgary, Alberta, Canada; ⁴Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada; ⁵Calgary Stroke Program, Foothills Medical Centre, Calgary Health Region, Calgary, Alberta, Canada; ⁶Radiology, University of Calgary, Calgary, Alberta, Canada

                  1549.    Assessment of the Computational Efficiency of Perfusion Deconvolution Algorithms for Application to Acute Stroke

Sylvia Drabycz¹, J Ross Mitchell¹

¹University of Calgary, Calgary, Alberta, Canada

                  1550.    Digital Anthropomorphic Perfusion Phantom for the Evaluation of DSC-MR Perfusion Algorithms

Jayme C. Kosior¹, ², Richard Frayne, ¹²

¹University of Calgary, Calgary, Alberta, Canada; ²Foothills Medical Centre, Calgary Health Region, Calgary, Alberta, Canada

                  1551.    Improving the Sensitivity of Total Cerebral Blood Flow Measurement by Cine Phase Contrast MRI

Noam Alperin¹, Sang H. Lee¹

¹University of Illinois at Chicago, Chicago, Illinois, USA

                  1552.    Demonstration of Direct and Complete Collateral Compensation During Carotid Artery Compression
                                by MR Flow Monitoring

Jan-Henry Seppenwoolde¹, Jeroen Hendrikse¹, Henk Johan Nanang Streefkerk², Berend Hillen², Chris J.G. Bakker¹

¹University Medical Center Utrecht, Utrecht, Netherlands; ²University Medical Center St Radboud, Nijmegen, Netherlands

Pediatric Brain

                  1553.    Association Between MR Changes Early in Therapy and Later Neurocognitive Performance
      in Children Treated for Acute Lymphoblastic Leukemia

Wilburn E. Reddick¹, Courtney L. Dirksen¹, John O. Glass¹, Cheng Cheng¹, Ching-Hon Pui¹

¹St. Jude Children's Research Hospital, Memphis, Tennessee, USA

                  1554.    Relationship of Temporal Lobe Volume to Neuropsychological Test Performance in Healthy Children
                                and Adolescents

Carolyn Theresa Wells¹, Ernest Mark Mahone¹, Melissa Matson¹, Wendy R. Kates¹, ², Trisha Hay², Alena Horska³

¹Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; ²SUNY Upstate Medical University, Syracuse, New York, USA; ³Johns Hopkins University, Baltimore, Maryland, USA

                  1555.    Non-Invasive Imaging of Endogenous Magnetic Particle Deposits in Biological Tissue Using
                                Magnetic Resonance Imaging

Heath Pardoe¹, Gaby S. Pell¹, Graeme D. Jackson¹

¹Brain Research Institute, Melbourne, Victoria, Australia

                  1556.    Cerebral Gray and White Matter T2 in Autism Spectrum Disorder

Helen Petropoulos¹, Seth D. Friedman¹, Dennis W. Shaw¹, Alan A. Artru¹, Geraldine Dawson¹, Stephen R. Dager¹

¹University of Washington, Seattle, Washington, USA

                  1557.    Diffusion Tensor Imaging Findings in Rett Syndrome Patients

Izlem Izbudak¹, Luciano Farage¹, David Bonekamp¹, Weihong Zhang¹, Genila Bibat², Sussumu Mori¹,

SakkuBai Naidu², Alena Horska¹

¹Jonhs Hopkins Medical Institutions, Baltimore, Maryland, USA; ²Kennedy Krieger Institute, Baltimore, Maryland, USA

                  1558.    Faster Quantitative Brain Imaging in Pediatric Patients by Using IR-TrueFISP

Claudia Maria Hillenbrand¹, Ralf Berthold Loeffler¹, John O. Glass¹, Wilburn Eugene Reddick¹

¹St. Jude Children's Research Hospital, Memphis, Tennessee, USA

                  1559.    In Vivo Detection of Age-Related Brain Iron Differences with MFC

Anita Ramani¹, Jens H. Jensen¹, Amy L. Krain¹, Jing Yang¹, Caixia Hu¹, Hanzhang Lu¹, Joseph A. Helpern¹

¹New York University School of Medicine, New York, New York, USA

                  1560.    Comparison of BOLD Signal Changes in the Fetal Brain at 3T with Local PO2 Measurements

Ulrike Wedegärtner¹, Andrew N. Priest¹, Hendrik Kooijman², Mikhail Tchirikov¹, Hobe J. Schröder¹, Gerhard Adam¹

¹University Hospital Hamburg-Eppendorf, Hamburg, Germany; ²Philips Medical Systems, Hamburg, Germany

                  1561.    Quantitative MR Imaging and Spectroscopy in Childhood White Matter Disorders

Patrick van der Voorn¹, Petra J.W. Pouwels¹, Augustinus A.M. Hart², Frederik Barkhof¹, Marjo S. van der Knaap¹

¹VU University Medical Center, Amsterdam, Netherlands; ²Academic Medical Center, Amsterdam, Netherlands

                  1562.    Fast 3D Pediatric Brain MRSI

Dong-Hyun Kim¹, Meng Gu², Charles Cunningham², Albert Chen¹, Fiona Baumer¹, Orit Glenn¹, Daniel Vigneron¹, Daniel Spielman², Anthony James Barkovich¹

¹University of California, San Francisco, California, USA; ²Stanford University, Stanford, California, USA



 

Neuro-Oncology

                  1563.    Evaluating the Impact of Cancer Therapy on the Developing Brain

Wilburn E. Reddick¹, John O. Glass¹, Jinesh J. Jain¹, Nicholas S. Phillips¹, Qing Ji¹, Robert J. Ogg¹,

Thomas E. Merchant¹, Amar Gajjar¹

¹St. Jude Children's Research Hospital, Memphis, Tennessee, USA

                  1564.    Longitudinal Evaluation of HSV Brain Tumor Therapy Using Diffusion Tensor MR Imaging

Wei Bian¹, Narasimha Shastry Akella¹, Steven T. Moore¹, William T. Evanochko¹, Matthias Karrasch², Axel Mescheder², James M. Markert¹, Louis B. Nabors¹

¹University of Alabama at Birmingham, Birmingham, Alabama, USA; ²Medigene AG, Munich, Germany

                  1565.    Computer-Aided Detection of Brain Tumor Invasion Using Morphological and Diffusion-Weighted MR

Todd Robert Jensen¹, ², Xin Feng¹, John L. Ulmer², Kathleen M. Schmainda²

¹Marquette University, Milwaukee, Wisconsin, USA; ²Medical College of Wisconsin, Milwaukee, Wisconsin, USA

                  1566.    The Added Value of MRS in Brain Tumor Diagnosis

Margarida Julià-Sapé¹, Indira E. Coronel¹, Marta Serrallonga², Carles Majós², Ana Paula Candiota¹, Mònica Cos², Oscar Godino³, Juan-José Acebes³, Carles Aguilera², Carles Arús¹

¹Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Barcelona, Spain; ²IDI-Bellvitge, Institut de Diagnòstic per la Imatge, L'Hospitalet del Llobregat, Barcelona, Spain; ³Hospital Universitari de Bellvitge, L'Hospitalet del Llobregat, Barcelona, Spain

                  1567.    Supervised Pattern Recognition for Predicting the Appearance of Contrast-Enhancement in
                                High-Grade Gliomas Using Multimodality MRI and MRSI

Michael C. Lee¹, Susan M. Chang¹, Sarah J. Nelson¹

¹University of California, San Francisco, California, USA

                  1568.    Lessons from Functional Brain Mapping in Pre- And Intra- Operation for Low-Grade Glioma:
                                Insights Into Associations Between Tumour and Brain Plasticity

Zi Xiao Li¹, Jian Ping Dai¹, Tao Jiang², Shao Wu Li¹, Zhong Zhang², Cai Jie Duan³, Yi Lin Sun⁴, Pei Yi Gao¹, Jun Ma¹

¹The Capital University of Medical Science Affiliated Beijing Tian Tan Hospital, Beijing, People’s Republic of China; ²The Capital University of Medical Science Affiliated Beijing Tian Tan Hospital, Beijing, Chile; ³Beijing University, Beijing, People’s Republic of China; ⁴Beijing Neurosurgery Institute, Beijing, People’s Republic of China

                  1569.    Comparison of MRI Contrast Enhancement by Motexafin Gadolinium and Omniscan in Glioblastoma Multiforme

Genevieve Ning Wu¹, Judith M. Ford¹, Robert B. Lufkin¹, Jeffry R. Alger¹

¹Univ. of California at Los Angeles, Los Angeles, California, USA

                  1570.    Imaging Blood Vessel Volume in High Grade Gliomas at 3T Using Susceptibility-Weighted
                                Imaging and Dynamic Susceptibility Contrast Perfusion MRI

Janine M. Lupo¹, Michael C. Lee¹, Soonmee Cha¹, Susan M. Chang¹, Sarah J. Nelson¹

¹University of California, San Francisco, California, USA

                  1571.    Multi-Parametric Composite Maps in Recurrent Brain Tumor Patients

Kathryn M. McMillan¹, Baxter P. Rogers¹, Cheng Guan Koay², M Elizabeth Meyerand³

¹Vanderbilt University, Nashville, Tennessee, USA; ²NIH, Bethesda, Maryland, USA; ³University of Wisconsin, Madison, Wisconsin, USA

                  1572.    Quantitative Characterization of Functional and Morphological Properties of
                                Tumor Vasculature in High-Grade Gliomas

Vijaya Nagesh¹, Thomas L. Chenevert¹, Larry Junck¹, Christina I. Tsien¹, Brian D. Ross¹, Theodore S. Lawrence¹,

Yue Cao¹

¹University of Michigan, Ann Arbor, Michigan, USA

                  1573.    Accuracy Evaluation of a First-Pass Pharmacokinetic Model (FPPM) for Simultaneous Mapping
                                of Blood Volume and Microvascular Permeability in Brain Tumors

Hua-Shan Liu¹, ², Hsiao-Wen Chung¹, ², Ming-Chung Chou¹, ², Chun-Jung Juan¹, ², Cheng-Yu Chen²

¹National Taiwan University, Taipei, Taiwan, Taiwan; ²Tri-Service General Hospital, Taipei, Taiwan, Taiwan

                  1574.    Permeability Fitting of DSC Perfusion Data Through Constrained Optimization

Talin Tasciyan¹

¹Medical Numerics Inc, Sterling, Virginia, USA

                  1575.    Comparison of T1 to T2* Derived Parametric Maps in Brain Tumor Patients

Matthew L. Zierhut¹, ², Soonmee Cha², Michael C. Lee², Mary Katherine Mayo², Sarah J. Nelson¹, ²

¹UCSF/UCB Joint Graduate Group in Bioengineering, San Francisco, California, USA; ²UCSF, San Francisco, California, USA

                  1576.    rCBV Estimates in Tumor vs. Normal Brain Depend on Acquisition and Analysis Methods

Eric Scott Paulson¹, Douglas Edward Prah¹, Kathleen M. Schmainda¹

¹Medical College of Wisconsin, Milwaukee, Wisconsin, USA



 

Metabolic and White Matter MRS

                  1577.    Reproducibility of ¹H-MR Spectroscopic Imaging in the Centrum Semi-Ovale in Patients with Multiple Sclerosis

Jop Mostert¹, Jeroen van der Grond², Jacques De Keyser¹, Hans Hoogduin¹

¹University Medical Center Groningen, University of Groningen, Groningen, Netherlands; ²University Medical Center Leiden, Leiden, Netherlands

                  1578.    Whole Brain N-Acetylaspartate Concentration as a Surrogate Marker for Benign Multiple Sclerosis

Daniel Rigotti¹, Tyson Oberndorfer¹, James Babb¹, Clyde Markowitz², Joseph Herbert¹, Oded Gonen¹

¹NYU School of Medicine, New York, New York, USA; ²UPenn Medical Center, Philadelphia, Pennsylvania, USA

                  1579.    Brain Metabolism in Primary Progressive Multiple Sclerosis:A Three-Dimensional Proton
                                MR Spectroscopy Study at 3T

Meredith Spindler¹, Sarah Brown¹, Joseph Herbert¹, Hina Jaggi¹, Matilde Inglese¹, Oded Gonen¹

¹New York University, New York, New York, USA

                  1580.    Temporal Lobe Biochemistry and Non-Verbal Neurocognitive Function in Myotonic Dystrophy

            Type I

Deidre J. Devier¹, Charles Gasparovic, ¹², Rex E. Jung¹, ², Richard Campbell¹, Alejandro Tobon¹, Leslie Morrison¹

¹University of New Mexico, Albuquerque, New Mexico, USA; ²MIND Institute, Albuquerque, New Mexico, USA

                  1581.    Metabolic Changes in Juvenile Myoclonic and Frontal Lobe Epilepsy by ¹H MR Spectroscopy

Hyun-Man Baik¹, Barbara Swartz², Long Vu¹, Hui Liu¹, O. Nalcioglu¹, Min-Ying Su¹

¹University of California-Irvine, Irvine, California, USA; ²Haog Hospital, Newport Beach, California, USA

                  1582.    Quantitative MR Spectroscopy for Monitoring Treatment of Cerebrotendinous Xanthomatosis

Eva H. Baker¹, Jennifer L. McKeon¹, Robert D. Shamburek¹

¹NIH, Bethesda, Maryland, USA

                  1583.    Blind Recovery of 1H MRSI Spectral Signatures of Batten Disease and Melas

Shuyan Du¹, Xiangling Mao², Paul Sajda¹, Dikoma C. Shungu²

¹Columbia University, New York, New York, USA; ²Weill Medical College of Cornell University, New York, New York, USA

                  1584.    Serial Proton MRS of Neurometabolic Alterations in Hereditary Spastic Paraplegia with Thin Corpus
                                Callosum (HSP-TCC)

Steffi F. Dreha-Kulaczeski¹, Knut Brockmann¹, Gunther Helms¹, Jens Frahm², Jutta Gärtner¹, Peter Dechent¹

¹Georg-August-University, Goettingen, Lower Saxony, Germany; ²Biomedizinische Forschungs GmbH am MPI für biophysikalische Chemie, Goettingen, Lower Saxony, Germany

                  1585.    Assessment of the Metabolic Changes in Type 2 Diabetes Mellitus Using Magnetic Resonance Spectroscopy

Shilpi Modi¹, Manisha Bhattacharya¹, S S. Kumaran¹, T Sekhri¹, S Khushu¹

¹INMAS, Delhi, India

                  1586.    Use of Opioids in Asphyxiated Term Neonates: Effect on Brain Metabolites and Outcomes

Barbara Holshouser¹, Danilyn M. Angeles², Nathaniel D. Wycliffe¹, Douglas Deming¹, Carrie Carr²,

Lawrence C. Sowers², Stephen Ashwal¹

¹Loma Linda University Medical Center, Loma Linda, California, USA; ²Loma Linda University, Loma Linda, California, USA

                  1587.    Anti-TNF-Alpha Does Not Cause Acute Demyelination

Bart Jeroen Emmer¹, A E. van der Bijl¹, F C. Breedveld¹, T W. Huizinga¹, M A. van Buchem¹, J van der Grond¹

¹Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands


 

Brain Registration and Normalization Techniques

                  1588.    Robust Anatomy Recognition for Automated MR Neuro Scan Planning

Stewart Young¹, Daniel Bystrov¹, Thomas Netsch¹, Rene Bergmans², Arianne van Muiswinkel², Fredy Visser²,

Rudolf Springorum², Frank Hoogenraad², Jürgen Gieseke³

¹Philips Research, Hamburg, Germany; ²Philips Medical Systems, Best, Netherlands; ³University of Bonn, Bonn, Germany

                  1589.    Iterative Tensor-Based Registration

Ravichandran Rajaram¹, Carlo Ciulla¹, E Mark Haacke¹

¹The MRI Institute for Biomedical Research, Detroit, Michigan, USA

                  1590.    Comparison of Two Spatial Normalization Methods in the Elderly Brain

Weiying Dai¹, Owen T. Carmichael, ¹², Oscar L. Lopez¹, H. Michael Gach, ¹³

¹University of Pittsburgh, Pittsburgh, Pennsylvania, USA; ²Carnegie Mellon University, Pittsburgh, Pennsylvania, USA; ³Nevada Cancer Institute, Las Vegas, Nevada, USA

                  1591.    Evaluation of a Symmetric Diffeomorphic Registration Algorithm for Analyzing Neurodegenerative Disease

Brian Avants¹, James Gee¹, Murray Grossman¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA

                  1592.    Non-Rigid Registration of Functional to Anatomical Brain MR Images Using Constrained Optimization

Ali Gholipour¹, Nasser Kehtarnavaz¹, Kaundinya Gopinath², Richard Briggs², Michael Devous², Robert Haley²

¹University of Texas at Dallas, Richardson, Texas, USA; ²University of Texas Southwestern Medical Center, Dallas, Texas, USA

                  1593.    Automated Versus Manual Scan Positioning: A Quantitative Analysi

Rudolf Springorum¹, Frank Hoogenraad¹, Rene Bergmans¹, Stewart Young², Daniel Bystrov², Clemens Bos¹

¹Philips Medical Systems, Best, Netherlands; ²Philips Research, Hamburg, Germany

                  1594.    Measurement of Subpixel Motion of the Lateral Ventricular Walls

Mark E. Wagshul¹, Michael R. Egnor¹, James Manzione¹, Erin J. McCormack¹, Abram Voorhees², Timothy Wei³

¹Stony Brook University, Stony Brook, New York, USA; ²New York University, New York, New York, USA; ³Rutgers University, New Brunswick, New Jersey, USA

                  1595.    Realignment Strategies in ASL Timeseries

Karam Sidaros¹, Anders Jespersen², Torben E. Lund¹

¹Copenhagen University Hospital Hvidovre, Hvidovre, Denmark; ²Copenhagen University Hospital Frederiksberg, Copenhagen, Denmark

                  1596.    Measurement of Pulsatile Brain Motion in a Patient with a Meningioma

Michaela Soellinger¹, Andrea Kaspar Rutz¹, Sebastian Kozerke¹, Miroslava Bjeljac², Peter Boesiger¹

¹University and ETH Zurich, Zurich, Switzerland; ²University Hospital Zurich, Zurich, Switzerland


 

Brain Segmentation Techniques

                  1597.    Improved Segmentation of Intracranial Volumes Using a Combination of T1- And T2-Weighted 3D MRI

Gunther Helms¹, Kai Kallenberg¹, ², Peter Dechent¹

¹Göttingen University, Faculty of Medicine, Göttingen, Germany; ²Göttingen University, Göttingen, Germany

                  1598.    Reproducibility of Automated Brain Morphometric Estimates Derived from Multi-Site Structural MRI Studies

Jorge Jovicich¹, Silvester Czanner¹, Xiao Han¹, Douglas Greve¹, Jenni Pacheco¹, Evelina Busa¹,

Andre van der Kouwe¹, Bruce Fischl¹, ², Anders Dale³

¹1MGH/MIT/HMS Athinoula Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA; ²Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; ³University of California San Diego, San Diego, California, USA

                  1599.    Segmentation of Gray- And White Matter on MR Brain Images in Multiple Sclerosis

Sushmita Datta¹, Balasrinivasa Rao Sajja¹, Renjie He¹, Jerry S. Wolinsky¹, Ponnada A. Narayana¹

¹Medical School, The University of Texas at Houston, Houston, Texas, USA

                  1600.    Histogram-Based Acceleration on EM Algorithm for Segmentation of Multi-Spectral MRI with
                                Contextual Constrains

Renjie He¹, Sushmita Datta¹, Balasrinivasa Rao Sajja¹, Ponnada A. Narayana¹

¹University of Texas Medical School at Houston, houston, texas, USA

                  1601.    Virtual Definition of Tissue by Cluster Analysis of Multi-Parametric MR Imaging (Virtual-Dot-Com Imaging)

Yossi Yovel¹, Yaniv Assaf¹, ²

¹Tel Aviv University, Tel Aviv, Israel; ²Tel Aviv Sourasky Medical Cener, Tel Aviv, Israel

                  1602.    Optimum Template Selection for Atlas-Based Segmentation

Minjie Wu¹, Jessica LoSurdo¹, Pilar Lopez-Garcia², Cameron Stuart Carter², Howard Jay Aizenstein¹

¹University of Pittsburgh, Pittsburgh, Pennsylvania, USA; ²University of California at Davis, Sacramento, California, USA

                  1603.    Significant Local Shape Differences of the Brain Ventricles in Alzheimer’s Patients Compared to Healthy Elderly

Luca Ferrarini¹, Walter Miguel Palm¹, Hans Olofsen¹, Mark A. van Buchem¹, Johan H C Reiber¹,

Faiza Amiraal-Behloul¹

¹Leiden University Medical Center, Leiden, Netherlands

                  1604.    Segmentation of Age-Related White-Matter Changes in a Large-Scale, Multi-Centre Study

Tim Dyrby¹, Egill Rostrup¹, Elisabeth Catherine Wilhelmina van Straaten², Frederik Barkhof², Stefan Ropele³,

Lars Kai Hansen⁴, Gunhild Waldemar⁵

¹Copenhagen University Hospital, Hvidovre, Copenhagen, Denmark; ²VU Medical Center, Amsterdam, Netherlands; ³Karl Franzens University, Graz, Austria; ⁴Danish Technical University, Copenhagen, Denmark; ⁵Copenhagen Univ. Hospital, Rigshospitalet, Copenhagen, Denmark

                  1605.    Automatic Cortex Extraction and Gray/White Matter Segmentation from T1-Weighted MRI
                                with Geodesic Active Contours

Albert Huang¹, Rafeef Abugharbieh¹, Roger Tam¹, Anthony Traboulsee¹

¹The University of British Columbia, Vancouver, BC, Canada

                  1606.    The Size of Corpus Callosum Normalized by the Intracranial or Brain Parenchymal Volume Exhibits
                                a Significant Difference Between Male and Female Brains

Nobuhiro Takaya¹, Hidehiro Watanabe¹, Fumiyuki Mitsumori¹

¹National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan

                  1607.    De-Scalping of the Brain in Echo Planar DT-MRI

Ankur Purwar¹, RK Gupta², Manoj Kumar Sarma¹, Getaneh Bayu¹, Anup Singh¹, Divya KS Rathore¹, Sona Saksena², Richa Trivedi², Ashtmangal Mishra², Mohammad Haris², P Mohan², RKS Rathore¹

¹Indian Institute of Technology, Kanpur, UP, India; ²Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, UP, India

                  1608.    A Simple Method for the Automatic Measurement of Cortical Thickness

Don C. Bigler¹, Qing X. Yang¹, Michael B. Smith¹

¹Penn State College of Medicine, Hershey, Pennsylvania, USA

                  1609.    Semi-Automated Segmentation of Brain Tumor Lesions in MR Images

Suja Saraswathy¹, Forrest Crawford¹, Sarah J. Nelson¹

¹University of California, San Francisco, California, USA

                  1610.    Brain Tumor Image Segmentation Using Neural Networks

Miguel Martín-Landrove¹, Raúl Villalta¹

¹Centro de Resonancia Magnética, Facultad de Ciencias, Universidad Central de Venezuela, Caracas, District of Columbia, Venezuela


 

Diffusion Modeling and its Application to Microstructure

                  1611.    A Model of Diffusion Weighted MRI in Grey Matter - A Multiparametric Approach Using Global Solutions

Peter Vestergaard-Poulsen¹, ², Brian Hansen¹

¹Aarhus University, Aarhus, Denmark; ²Aarhus University Hospital, Aarhus, Denmark

                  1612.    A Finite Difference Model of Diffusion Applied to Ischemia

Kevin D. Harkins¹, Jean-Philippe Galons¹, Timothy W. Secomb¹, Joe L. Divijak¹, Theodore P. Trouard¹

¹University of Arizona, Tucson, Arizona, USA

                  1613.    Diffusion Weighted Signal at Short Times in the Presence of Impermeable Interfaces

Astrid From Frøhlich¹, ², Leif Østergaard¹, Valerij G. Kiselev²

¹Aarhus University Hospital, Aarhus, Denmark; ²University Hospital Freiburg, Freiburg, Germany

                  1614.    Analysis of Water Diffusion and Magnetization Transfer Ratio in Optic Nerves After Crush Injury

Masaya Takahashi¹, Timothy K. Vartanian¹, David B. Hackney¹

¹Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

                  1615.    Decreased Diffusion Coefficients in Suspected Prostate Cancer Regions in Peripheral Zone:
                                A Comparison with Increased (Cho + Cr)/Cit Ratios from Magnetic Resonance Spectroscopy

Agnieszka Szot Barnes¹, Steven J. Haker¹, Stephan E. Maier¹, Clare m. Tempany¹, Robert V. Mulkern¹

¹Brigham and Women's Hospital, Boston, Massachusetts, USA

                  1616.    Q-Space Analysis of Intracellular Water Diffusion in Cultured Cells

Jean-Philippe Galons¹, Joseph L. Divijak¹, Silvia Lope-Piedrafita¹, Kevin Harkins¹, Robert J. Gillies¹,

Theodore Trouard¹

¹University of Arizona, Tucson, Arizona, USA

                  1617.    Separating Intra- And Extracellular Water Signals in Rat Brain Using Gd-DPTA-Enhanced
                                Diffusion-Weighted MRI

Timothy Michael Shepherd¹, Peter Edward Thelwall¹, Christopher M. Sotak², Stephen John Blackband¹

¹University of Florida, Gainesville, Florida, USA; ²Worcester Polytechnic Institute, Worcester, Massachusetts, USA

                  1618.    Multi-Component Apparent Diffusion Coefficients in the Rabbit VX2 Tumor Model

Jie Deng¹, Thomas K. Rhee¹, Gayle E. Woloschak¹, Tatjana Paunesku¹, Reed A. Omary¹, Andrew C. Larson¹

¹Northwestern University, Chicago, Illinois, USA

                  1619.    The Intracellular Water Diffusion Coefficient of Cultured Microbead-Adherent HeLa Cells is ≥ 1 µm²/ms

Lin Zhao¹, Christopher D. Kroenke¹, Joseph J. H. Ackerman¹, Jeffrey J. Neil¹

¹Washington University in St. Louis, St. Louis, Missouri, USA

                  1620.    Subcompartmental Cesium Diffusion in Healthy and Globally Ischemic Rat Brain

James A. Goodman¹, Joseph J.H. Ackerman¹, Jeffrey J. Neil¹

¹Washington University in St. Louis, St. Louis, Missouri, USA

                  1621.    Diffusion Exchange Weighted (DEW) Imaging

Saadallah Ramadan¹, Carolyn Mountford¹

¹Institute for Magnetic Resonance Research, Sydney, NSW, Australia

                  1622.    Accuracy of Q-Space Derived Parameters in MRI - A Phantom Study of System-Induced Limitations

Jimmy Lätt¹, Daniel Topgaard¹, Ronnie Wirestam¹, Carin Malmborg¹, Olle Söderman¹, Freddy Ståhlberg¹, Sara Brockstedt¹

¹Lund University, Lund, Sweden

                  1623.    Diffusion Weighted µMRI of Isolated Human Pancreatic Islets

Muhammad E. Haque¹, Suraj D. Serai², Lara Leoni¹, Robert V. Honeychuck³, Jose Oberholzer⁴, Brian B. Roman¹

¹University of Chicago, Chicago, Illinois, USA; ²University of Illinois at Chicago, Chicago, Illinois, USA; ³George Mason University, Fairfax, Virginia, USA; ⁴University of Illinois, Chicago, Illinois, USA

                  1624.    Localization Regime of Restricted Diffusion in a Model Pulmonary Acinus

Denis S. Grebenkov¹, Geneviève Guillot¹

¹C.N.R.S. UMR8081 Université Paris-Sud, Orsay, France

                  1625.    Dependence of Apparent Diffusion Coefficient on Cellular Structure

Dmitry S. Novikov¹, Valerij G. Kiselev²

¹Princeton University, Princeton, New Jersey, USA; ²University Hospital Freiburg, Freiburg, Germany

                  1626.    Microscopic MRI Assessment of Human Articular Cartilage Degeneration Using Q-Space Analysis

Shadi F. Othman¹, Osama Abdullah¹, Richard L. Magin¹, Xiaohong Joe Zhou¹

¹University of Illinois at Chicago, Chicago, Illinois, USA

                  1627.    Diffusive Diffraction Measured with MRI at 7T

Egbert Gedat¹, Susanne Müller², Thomas Tolxdorff¹, Jürgen Braun¹

¹Institut für Medizinische Informatik, Berlin, Germany; ²Klinik für Neurologie, Berlin, Germany

                  1628.    The Variance of DTI-Derived Parameters Via First-Order Perturbation Methods

Lin-Ching Chang¹, Carlo Pierpaoli¹, Peter J. Basser¹

¹NIH, Bethesda, Maryland, USA

                  1629.    Modelling Uncertainty in Two Fibre-Orientation Estimates Within a Voxel

Philip A. Cook¹, Daniel C. Alexander¹

¹University College London, London, UK

                  1630.    Sensitivity of Diffusion-Weighted-Steady State Free Precession to Diffusion Anisotropy

Jennifer Andrea McNab¹, Karla L. Miller¹

¹University of Oxford, Oxford, UK

                  1631.    Numerical Simulation of Double Wave Vector Diffusion Experiments

Martin A. Koch¹, Jürgen Finsterbusch¹

¹University Medical Center Hamburg-Eppendorf, Hamburg, Germany

                  1632.    Isoflurane Strongly Affects the Diffusion of Intracellular Metabolites in the Brain, Revealing the
     Contribution of Subcellular Restriction to Metabolite ADC

Julien Valette¹, Martine Guillermier², Philippe Hantraye, ¹², Gilles Bloch¹, Vincent Lebon¹

¹CEA-SHFJ, Orsay, France; ²URA CEA-CNRS 2210, Orsay, France

                  1633.    Effects of Cellular Mitosis on the Apparent Diffusion Coefficient of Synchronized HeLa Cells

Daniel C. Colvin¹, Natasha Deane¹, Coe Foutch¹, Mark D. Does¹, John C. Gore¹

¹Vanderbilt University, Nashville, Tennessee, USA