Myocardial Function and Strain Analysis

Room 4E                    Tuesday 13:30 - 15:30

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                  1634.    Single Breath-Hold Whole-Heart 3D CINE Imaging Using Kt-BLAST and Kt-SENSE

Marcus Katoh1, Elmar Spuentrup1, Arno Buecker1, Marc Kouwenhoven2, Jürgen Bunke2, Rolf W. Guenther1,

Thoralf Niendorf1, Thoralf Niendorf1

1RWTH Aachen University Hospital, Aachen, Germany; 2Philips Medical Systems, Best, Netherlands

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                  1635.    Fast 3D Cine Steady-State Free Precession Imaging with Sensitivity Encoding for Assessment of
                                Left Ventricular Function in a Single Breath-Hold

Neil B. Mascarenhas1, Raja Muthupillai2, 3, Benjamin Cheong2, Mercedes Pereyra2, Scott D. Flamm, 12

1Baylor College of Medicine, Houston, Texas, USA; 2St. Luke's Episcopal Hospital/Texas Heart Institute, Houston, Texas, USA; 3Philips Medical Systems, Cleveland, Ohio, USA

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                  1636.    Single Breath-Hold 3D Cine Imaging of the Heart: A Non-Angulated Isotropic Acquisition Using
                                SENSE on a 32 Channel System

Vivek Muthurangu1, Nicholas MI Noble2, Redha Boubertakh1, Richard Winkelmann3, Peter Börnert4, Derek L. G. Hill2, Reza S. Razavi1

1King's College London, London, UK; 2University College London, London, UK; 3University of Karlsruhe, Karlsruhe, Germany; 4Philips Research Laboratories, Hamburg, Germany

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                  1637.    Minimized Off-Resonance Effects with Centric Radial SSFP for Imaging Cardiac Function

Matthew D. Robson1, Stefan Neubauer1

1Oxford University, Oxford, Oxfordshire, UK

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                  1638.    A Reproducibility Comparison of Quantitative Left Ventricular Assessments in Healthy Volunteers
                                Using Different MRI Scanners - Implications for Multicentre Cardiac MRI Studies

Stephen J. Gandy1, Shelley A. Waugh1, R Stephen Nicholas1, Helen Simpson2, Wendy Milne1, Tracy Rylott3,

J Graeme Houston1

1NHS Tayside, Ninewells Hospital, Dundee, Angus, UK; 2School of Medicine, University of Dundee, Dundee, Angus, UK; 3NHS Tayside, Perth Royal Infirmary, Perth, Perthshire, UK

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                  1639.    Range of Biventricular Dimensions and Function Evaluated by Steady State Free Precession
                                Cine Magnetic Resonance in Patients with Repaired Tetralogy of Fallot

Margaret Mary Samyn1, Andrew J. Powell1, Ruchira Garg1, Laureen Sena1, Tal Geva1

1Children's Hospital Boston, Boston, Massachusetts, USA

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                  1640.    Longitudinal, Radial, and Circumferential Myocardial Velocities in Patients with Ventricular Dyssynchrony

Jana Delfino1, Mobit Bhasin, Angel Leon, Robert Eisner, John Oshinski1

1Georgia Institute of Technology/ Emory University, Atlanta, Georgia, USA

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                  1641.    Pre- And Postcontrast Three-Dimensional Cardiac Cine MRI Using SENSE and K-T BLAST

Yasuo Amano1, Tatsuo Kumazaki1, Yuriko Suzuki2

1Nippon Medical School, Tokyo, Japan; 2Philips Medical System, Tokyo, Japan

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                  1642.    Acquisition of Black-Blood Cine Cardiac Images in a Single Heartbeat at 3.0T

Ahmed S. Fahmy1, Li Pan1, Nael F. Osman1

1Johns Hopkins University, Baltimore, Maryland, USA

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                  1643.    A Double Navigator Approach to Double Inversion Recovery Fast Spin Echo Imaging in Black Blood
                                Cardiac MRI

Pascal Spincemaille1, Thanh D. Nguyen1, Martin Prince1, Yi Wang1

1Weill Medical College of Cornell University, New York, USA

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                  1644.    MR Compatible Heart Phantom for Medical Research

Holger Timinger1, Sascha Krueger1, Joern Borgert1

1Philips Research, Hamburg, Germany

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                  1645.    An MRI-Based Beating Heart Model

Qing Wei1, Stuart Crozier1, Ben Appleton1, Ling Xia2, Feng Liu1, Stephen Wilson1, Wendy Strugnell3,

Richard Slaughter3, Robyn Riley3

1The University of Queensland, Brisbane, Queensland, Australia; 2ZheJiang University, HangZhou, ZheJiang, People’s Republic of China; 3The Prince Charles Hospital, Brisbane, Queensland, Australia

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                  1646.    Balanced 2D Radial Acquisition SSFP of the Mouse Heart at 7 Tesla

Elizabeth Kathleen Bucholz1, G. Allan Johnson1

1Duke University, Durham, North Carolina, USA

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                  1647.    Direct Measurement of Intra Ventricular and Atrial Pressures Concurrent with MR Image Acquisiton

S. David Smith1, 2, Helene Benveniste2, 3, G. Ron Morris4, Svante Hojer5, Igor Izrailtyan3, Mei Yu2, Congwu Du2, Zhongchi Luo6, Yu Ma2, Hai-Dee Lee2, Igor Feinstein7

1INNOVISION Diagnostic Imaging Corp., Bellport, New York, USA; 2Brookhaven National Laboratories, Upton, New York, USA; 3Stony Brook Hospital, Stony Brook, New York, USA; 4SA Instruments, Inc., Stony Brook, New York, USA; 5Samba Instruments, Inc., Gotenburg, Sweden; 6Stony Brook University, Stony Brook, New York, USA; 7New York University, New York, New York, USA

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                  1648.    Slice Refocusing Signal for Retrospective Reconstruction of CINE Cardiac MR Images

Arno Nauerth1, Edwin Heijman2, Claudia Diekmann1

1Bruker BioSpin MRI GmbH, Ettlingen, Germany; 2Eindhoven University of Technology, Eindhoven, Netherlands

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                  1649.    Optimal Combination of Phase Cycling and Gradient Spoiling in DENSE Displacement Mapping

Eric Bennett1, Bruce Spottiswoode2, Christine H. Lorenz2, Han Wen1

1National Institutes of Health, Bethesda, Maryland, USA; 2Siemens, Bethesda, Maryland, USA

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                  1650.    Combining 2D DENSE and SENC to Calculate the 3D Strain Tensor

Aaron Timothy Hess1, Xiaodong Zhong2, Bruce Shawn Spottiswoode1, Frederick H. Epstein2, Ernesta M. Meintjes1

1University of Cape Town, Cape Town, Western Cape, South Africa; 2University of Virginia, Charlottesville, Virginia, USA

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                  1651.    DENSE and HARP: Two Views on the Same Technique of Phase-Based Strain Imaging

Joost Kuijer1, Mark B. Hofman1, Jaco J. Zwanenburg1, J. Tim Marcus1, Albert C. Van Rossum1, Rob M. Heethaar1

1VU University Medical Centre, Amsterdam, NL, Netherlands

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                  1652.    More Comprehensive Cardiac DENSE MR Imaging by Combination of Short Axis and Long Axis Data

Abbas Nasiraei Moghaddam1, Han Wen2, Morteza Gharib1

1California Institute of Technology, Pasadena, California, USA; 2NIH/NHLBI, Bethesda, Maryland, USA

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                  1653.    Fast 3D Dense Tracking of Cardiac Material Points Using ZHARP: In-Vivo Validation and Comparison
                                with 3D SF-HARP

Khaled Z. Abd-Elmoniem1, Matthias Stuber1, Jerry L. Prince1

1Johns Hopkins University, Baltimore, Maryland, USA

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                  1654.    Real-Time Single-Shot CINE Imaging of Through-Slice Strain in the Human Heart

Han Wen1, Eric Bennett1

1National Institutes of Health, Bethesda, Maryland, USA

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                  1655.    Navigator Gated High Temporal Resolution Tissue Phase Mapping of Myocardial Motion

Bernd André Jung1, Maxim Zaitsev1, Jürgen Hennig1, Michael Markl1

1University Hospital, Freiburg, Germany

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                  1656.    Toward True Myocardial Plannar Strain Using ZHARP: Experimental In-Vivo Validation

Khaled Z. Abd-Elmoniem1, Matthias Stuber1, Jerry L. Prince1

1Johns Hopkins University, Baltimore, Maryland, USA

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                  1657.    Comparison of Myocardial Velocities Obtained with Magnetic Resonance Phase Velocity Mapping
                                and Tissue Doppler Imaging in Normal Subjects and Patients with Left Ventricular Dyssynchrony

Jana Delfino1, Mobit Bhasin1, Robert Cole1, Angel Leon1, Robert Eisner1, John Merlino1, John Oshinski1

1Georgia Institute of Technology/ Emory University, Atlanta, Georgia, USA

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                  1658.    The Effect of Noise on the Accuracy of Strain Measurment When Using Strain Encoded (SENC) MRI

Tamer Yousef1, Nael F. Osman1

1Johns Hopkins University, Baltimore, Maryland, USA

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                  1659.    VaFA: Replacing CSPAMM

Vinay Manjunath Pai1, Daniel Kim1

1New York University, New York, New York, USA


 

Lung Imaging: Applications

Room 4E                    Tuesday 13:30 - 15:30

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                  1660.    Quantitative Regional Lung Ventilation- Results in 15 Single Lung Transplanted Patients

 

Hans-Georg Topf1, P Biondetti2, Maren Zapke1, Rainer Kuth3, M Deimling3, C Chefd´hotel4, B Geiger5,

Thomas Rupprecht6

1Childrens Hospital, Erlangen, Germany; 2Clinico, Milano, Italy; 3Siemens, Erlangen, Germany; 4Siemens, Princeton, U, USA; 5Siemens, U, Germany; 6Childrens Hospital, Bayreuth, Germany

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                  1661.    Is There a Diagnostic Potential of Magnetization Transfer MRI in Patients with Lung Cancer?

Johannes F. T. Arnold1, Markus Kotas1, Eberhard D. Pracht1, Michael Flentje1, Peter Michael Jakob1

1University of Würzburg, Würzburg, Bavaria, Germany

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                  1662.    The Role of Hyperpolarized 3-Helium MRI in NSCLC

Rob H. Ireland1, Mark McJury2, Matthew Q. Hatton3, Neil Woodhouse1, Edwin JR van Beek4, Jim M. Wild1

1University of Sheffield, Sheffield, UK; 2Belvoir Park Hospital, Belfast, UK; 3Weston Park Hospital, Sheffield, UK; 4University of Iowa, Iowa City, Iowa, USA

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                  1663.    Ventilation Heterogeneity Indices Computed from Hyperpolarized 3He MRI Captures Differences
                                Between Asthmatic and Non-Asthmatic Lungs

Yang-Sheng Tzeng1, 2, Niral Shah, 12, Joey Mansour1, Jessica Gereige1, George Washko1, Elliot Israel1,

Kenneth Lutchen2, Mitchell Albert1

1Brigham & Women's Hospital, Boston, Massachusetts, USA; 2Boston University, Boston, Massachusetts, USA

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                  1664.    Assessing the Temporal Changes of the Regional Ventilation in the Lungs of Asthmatics
                                with Hyperpolarized Helium-3 MR Imaging

Talissa A. Altes1, 2, John J. Battiston2, Adam P. Juersivich2, John P. Mugler2, Thomas AE Platts-Mills2,

Eduard E. de Lange2

1Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; 2University of Virginia, Charlottesville, Virginia, USA

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                  1665.    Comparison of Diffusion Weighted Helium-3 MRI in Patients with Asthma Versus Those with COPD

Sean B. Fain1, Tallissa A. Altes2, Rafael O'Halloran1, Ronald L. Sorkness1, Michael D. Evans1, Frank R. Korosec1, Thomas M. Grist1

1University of Wisconsin, Madison, Wisconsin, USA; 2University of Pennsylvania, Philadelphia, Pennsylvania, USA

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                  1666.    Helium-3 Apparent Diffusion Coefficient MRI Compared to CT in Emphysema Patients

Per Ĺkeson1, Sandra Diaz1, Ingrid Casselbrant1, Eeva Piitulainen1, Per Wollmer1, Göran Pettersson2, Peter Magnusson2, Barry Peterson3

1Malmö University Hospital, Malmö, Sweden; 2GE Healthcare, Malmö, Sweden; 3Pfizer Inc., Groton, Connecticut, USA

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                  1667.    Velocity Encoding MRI with SENSE: Utility for Assessment of Disease Severity in Pulmonary
                                Emphysema Patients

Munenobu Nogami1, Yoshiharu Ohno1, Hisanobu Koyama1, Daisuke Takenaka1, Masahiko Fujii1, Kazuro Sugimura1

1Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan

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                  1668.    Early Detection of Emphysema by Hyperpolarized Helium-3 MRI Through Measuring
                                Regional Fractional Ventilation

Kiarash Emami1, Martin Fischer1, Jianliang Zhu1, Masaru Ishii2, Vahid Vahdat1, Stephen Kadlecek1,

John MacDuffie Woodburn1, Michael E. Friscia1, JiangSheng Yu1, Rahim R. Rizi1, Joseph Shrager1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Johns Hopkins University, Baltimore, Maryland, USA


 

Muscle Spectroscopy

Room 4E                    Tuesday 13:30 - 15:30

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                  1669.    Measurement of Intramyocellular Lipids in Obese Subjects Using Spectroscopic Imaging with High Spatial Resolution

Jan Weis1, Lars Johansson2, Frederic Courivaud3, Anders Karlsson1, Hĺkan Ahlström1

1Uppsala University Hospital, Uppsala, Sweden, Sweden; 2Astra Zeneca R&D, Uppsala, Sweden, Sweden; 3Philips Medical Systems, Oslo, Norway, Norway

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                  1670.    Separation of the Intra- And Extracellular Apparent Diffusion Coefficients (ADC) of Water in
                                Rat Skeletal Muscle Using Spectroscopic MEMRI

Karl G. Helmer1, John G. Seland2, Nils Henninger3, Christopher H. Sotak1, 3

1Worcester Polytechnic Institute, Worcester, Massachusetts, USA; 2Norwegian University of Science and Technology, Trondheim, Norway; 3UMass/Memorial Healthcare, Worcester, Massachusetts, USA

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                  1671.    In Vivo Quantification of Intramyocellular Lipid in Mouse Hindleg Muscle

Rachida Fissoune1, Bassem Hiba2, Marc Janier2, André Briguet1

1Laboratoire de RMN CNRS UMR 5012, Lyon, France; 2Animage Plateforme of Small Animal Imaging, Lyon, France

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                  1672.    IMCL Changes During Moderate Endurance Exercise as Measured by Three Different Methods

Tom Dresselaers1, Katrien De Bock1, Paul Van Hecke1, Peter Hespel1

1K.U.Leuven, Leuven, Belgium, Belgium

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                  1673.    MRI Measurement of Advanced Glycation End Products: The MRI Hyperglycemic Damage Index

Andres Rahal1, Gary D. Fullerton1

1The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA

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                  1674.    1H-MRSI in Human Calf Muscles at 3T: Ordering Effects and Intra-Myocellular Lipids

Peter Vermathen1, Roland Kreis1, Chris Boesch1

1University & Inselspital, Berne, Switzerland

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                  1675.    Response of Insulin-Dependent Type 2 Diabetic Subjects to a 5-Month Exercise Training Program

Henk M.M.L. De Feyter1, Stephan S.F. Praet2, Luc J. van Loon2, Jeanine J. Prompers1, Klaas Nicolay1

1Eindhoven University of Technology, Eindhoven, Netherlands; 2Maastricht University, Maastricht, Netherlands

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                  1676.    Assesment of the Fat Content of Proximal Femur and Adjacent Muscle in Patients with Osteoarthritis

Trevor S. Ahearn1, Thomas W. Redpath1, Richard M. Aspden1, James D. Hutchison1, Scott I.K. Semple1, David J. Knight1

1University of Aberdeen, Aberdeen, UK

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                  1677.    PPARδ Agonist Treatment Increases Skeletal Muscle Lipid Metabolism Without Altering Mitochondrial Coupling:
                                An In Vivo Magnetic Resonance Spectroscopy Study

Dewen Yang1, Warren M. Casey1, Alan R. Olzinski1, Carolyn Williams1, Stephen C. Lenhard1, Jeffrey J. Legos1, Terrance C. Hawk1, Susanta K. Sarkar1, Steve J. Newsholme1, Beat M. Jucker1

1GlaxoSmithKline, King of Prussia, Pennsylvania, USA

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                  1678.    The Typical IMCL Distribution Pattern in Rat Tibialis Anterior Muscle Remains Unchanged
                                After High-Fat Diet or Fasting

Henk M.M.L. De Feyter1, Klaas Nicolay1, Jeanine J. Prompers1

1Eindhoven University of Technology, Eindhoven, Netherlands

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                  1679.    Magnetic Resonance Findings and Serum Creatine Kinase Measurements in Acute Human
                                Skeletal Muscle Injury

Tatiana Zaraiskaya1, Dinesh Kumbhare2, Michael D. Noseworthy1

1McMaster University, Hamilton, Ontario, Canada; 2St.Joseph's Healthcare, Hamilton, Ontario, Canada

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                  1680.    Reproducibility of Muscle Metabolism Parameters in Children Determined by  31P Spectroscopy

Jonathan Fulford1, Neil Armstrong1, Alan Barker1, Deborah Welford1, Joanne Welsman1

1University of Exeter, Exeter, Devon, UK

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                  1681.    In Vivo Assessment by 31P-MRS of Skeletal Muscle Mitochondrial Function in Patients on
                                Long-Term Home Parenteral Nutrition

Loris Pironi1, Emil Malucelli2, Cristina Guidetti1, Caterina Tonon2, Claudia Testa2, Raffaele Lodi2, Bruno Barbiroli2, Stefano Iotti2

1Universitŕ di Bologna, Bologna, Italy; 2University of Bologna, Bologna, Italy

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                  1682.    OPA1 Mutations Result in a Deficit of In Vivo Mitochondrial ATP Production in Patients with
                                Autosomal Dominant Optic Atrophy

R Lodi1, C Tonon1, D Manners1, E Malucelli1, C Testa1, M L. Valentino1, P Barboni2, S Schaich3, S Schimpf3,

B Wissinger3, V Carelli1, B Barbiroli1

1Universitŕ di Bologna, Bologna, Italy, Italy; 2Centro Salus, Bologna, Italy, Italy; 3Molekulargenetisches Labor der Universitats-Augenklinik, Tubingen, Germany, Germany

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                  1683.    Bioenergetic Defects in Muscles of Polymyositis Patients:  Quantitative MRI and P-31 MRS Investigation

Jing Qi1, 2, Nancy Josephine Olsen1, 3, Kenneth John Niermann1, Jane Harting Park1

1Vanderbilt University Medical School, Nashville, Tennessee, USA; 2Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; 3UT Southwestern Medical School, Dallas, Texas, USA

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                  1684.    Intersubject Differences in the Effect of Acidosis on Phosphocreatine Recovery Kinetics After Exercise

Jeanine J. Prompers1, Henk M.M.L. De Feyter1, Nicole M.A. van den Broek1, Larry A.H.J. de Graaf1, Klaas Nicolay1

1Eindhoven University of Technology, Eindhoven, Netherlands

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                  1685.    Mitochondrial Capacity and Oxygenation Measured by 31P MRS and Near Infrared Spectroscopy
                                in Healthy and Diabetic Subjects

Jonathan Fulford1, Rajagopalan Sriraman2, Claire Ball2, John Tooke2, Neil Armstrong1, Angela Shore2

1University of Exeter, Exeter, Devon, UK; 2Peninsula Medical School, Exeter, Devon, UK

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                  1686.    A Quantitative Study of Bioenergetics in Skeletal Muscle Lacking Carbonic Anhydrase III
                                by 31P Magnetic Resonance Spectroscopy

Min Liu1, Glenn Walter1, Neeti Pathare1, Un-jin Zimmerman2, Robert E. Forster2, Krista Vandenborne1

1University of Florida, Gainesville, Florida, USA; 2University of Pennsylvania, Philadelphia, Pennsylvania, USA

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                  1687.    Direct Quantification of Lactate and High Energy Phosphates in Exercising Human Skeletal Muscle
                                by Interleaved Localised 1H DQF, 1H- And 31P STEAM

Martin Meyerspeer1, Graham J. Kemp2, Vladimir Mlynárik1, Martin Krššák3, Julia Szendroedi1, Michael Roden4, Ewald Moser1, 3

1Vienna Medical University, Wien, Austria; 2University of Liverpool, Faculty of Medicine,, Liverpool, UK; 3Medical University of Vienna, Wien, Austria; 4Hanusch Hospital Vienna, Wien, Austria

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                  1688.    Energy Metabolism in the Extensor Muscles of the Hand and Wrist of Musicians with Overuse Syndrome
                                Studied by 31P-MRS

Angel Moreno-Torres1, Jaume Rosset2, Jesus Pujol3, Silvia Fŕbregas2

1Centre Diagnostic Pedralbes - Cetir Grup Mčdic, Esplugues de Llobregat, Spain; 2Institut de Fisiologia i Medicina de l’Art, Terrassa, Spain; 3Institut d’Alta Tecnologia, Barcelona, Spain

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                  1689.    Skeletal Muscle Hydrogen Ion Concentration Stimulates Ventilatory Drive Through Direct Neural Pathways
                                as Shown by 31P MRS

Christian Thomas Farrar1, Mirko I. Hrovat1, Anne V. LaRaia2, Gregory D. Lewis2, Paul P. Pappagianopoulos2,

David M. Systrom2

1Massachusetts General Hospital, Charlestown, Massachusetts, USA; 2Massachusetts General Hospital, Boston, Massachusetts, USA



 

MSK/Body: Spine, Bone, Muscle, Tendon, Misc.

Room 4E                    Tuesday 13:30 - 15:30

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                  1690.    Prediction of Bone Mechanical Properties Using Quantitative MRI

Eveliina Lammentausta1, Mikko Antero Hakulinen1, Ilkka Kiviranta2, Jukka Sakari Jurvelin1, 3, Miika Tapio Nieminen4

1University of Kuopio, Kuopio, Finland; 2Jyväskylä Central Hospital, Jyväskylä, Finland; 3Kuopio University Hospital, Kuopio, Finland; 4Oulu University Hospital, Oulu, Finland

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                  1691.    In-Vivo Micro-MRI of Trabecular Bone in the Ovariectomized Rhesus at 3T

Paul J. McCracken1, Marie A. Holahan1, Parker D. Mathers1, Jacquelynn J. Cook1, Donald B. Kimmel1,

Richard Hargreaves1, Le T. Duong1, Donald S. Williams1

1Merck Research Laboratories, West Point, Pennsylvania, USA

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                  1692.    In-Vivo MR Microscopy of Trabecular Structure of a Human Finger Using a Small Permanent Magnet

Nachiko Iita1, Katsumi Kose1

1University of Tsukuba, Tsukuba, Ibaraki, Japan

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                  1693.    Trabecular Bone Structure and Anisotropy Studies Via Diffusion-Based MR

Eric Edward Sigmund1, Hyungjoon Cho1, Yi-Qiao Song1, Steve Byrnes, 12, Peiqiu Chen, 12, Edward X. Guo3,

Truman Brown3

1Schlumberger-Doll Research, Ridgefield, Connecticut, USA; 2Harvard University, Cambridge, Massachusetts, USA; 3Columbia University, New York, New York, USA

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                  1694.    Measurements of Bone Marrow Proton Relaxation Times and Trabecular Bone Volume Fraction (TBVF)
                                of the Calcaneus for 100 Subjects Using a Compact MRI

Sadanori Tomiha1, Nachiko Iita1, Fumi Okada1, Shinya Handa1, Katsumi Kose1

1University of Tsukuba, Tsukuba, Ibaraki, Japan

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                  1695.    Pathophysiology of Bone Marrow Edema: Insights from Dynamic Contrast Enhanced MR Imaging

Edward W. Jung1, Glenn A. Tung1, Jonathan P. Dyke2, Jonathan H. Lee3, D McK Ciombor1, Roy K. Aaron1

1Brown Medical School, Providence, Rhode Island, USA; 2Weill Cornell Medical College, New York, New York, USA; 3Columbia University Medical School, New York, New York, USA

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                  1696.    Contrast-Enhanced MRI with Fat Suppression Using T1 Dispersion

Sharon E. Ungersma1, Nathaniel I. Matter1, Ross D. Venook1, Albert Macovski1, Greig C. Scott1, Garry E. Gold1, Steven M. Conolly2

1Stanford University, Stanford, California, USA; 2University of California, Berkeley, Berkeley, California, USA

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                  1697.    Water and Fat Suppressed Proton Projection MRI (WASPI) of Rat Femur Bone with Sub-Millimeter Resolution

Yaotang Wu1, Jerome L. Ackerman2, David A. Chesler2, Guangping Dai2, Mirko I. Hrovat3, Brian D. Snyder4,

Ara Nazarian4, Melvin J. Glimcher1

1Children's Hospital, Boston, Massachusetts, USA; 2Massachusetts General Hospital, Boston, Massachusetts, USA; 3Mirtech Inc, Brockton, Massachusetts, USA; 4Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

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                  1698.    Trabecular Bone Volume Fraction (TBVF) Measurements of 108 Young Children Using a Compact MRI

Sadanori Tomiha1, Katsumi Kose1, Naomi Omi1, Kayoko Kamemoto1

1University of Tsukuba, Tsukuba, Ibaraki, Japan

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                  1699.    MRI Characterization of Trabecular Bone Structure by Exploring Bone Microscopic Susceptibility Effect

Shing Chung Cheung1, Jian Yang1, Sai Kam Hui1, Ed Xuekui Wu1

1The University of Hong Kong, Pokfulam, Hong Kong, People’s Republic of China

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                  1700.    Basic Clinical Imaging Techniques in Prepolarized MRI

Nathaniel I. Matter1, Greig C. Scott1, Ross D. Venook1, Sharon E. Ungersma1, Thomas Grafendorfer, 1,2,

John M. Pauly1, Albert Macovski1, Steven M. Conolly, 1,2

1Stanford University, Stanford, California, USA; 2University of California at Berkeley, Berkeley, California, USA

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                  1701.    Prepolarized MRI:  Reducing Susceptibility Artifacts Around Metal Orthopedic Implants Without
                                Sacrificing Image Quality

Ross Venook1, Nathaniel Matter1, Meena Ramachandran1, Sharon Ungersma1, Garry Gold1, Nicholas Giori2,

Albert Macovski1, Greig Scott1, Steven Conolly3

1Stanford University, Stanford, California, USA; 2VA Palo Alto Healthcare System, Palo Alto, California, USA; 3U.C. Berkeley, Berkeley, California, USA

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                  1702.    Combined Rotational/Translational Motion Correction Using Autofocusing for High-Resolution
                                Trabecular Bone Images

Wei Lin1, Glenn Ladinsky1, Felix W. Wehrli1, Hee Kwon Song1

1University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

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                  1703.    Using the Phase for MR Image Segmentation: Application to the Bone of the Knee

Pierrick Bourgeat1, Peter Stanwell2, Saad Ramadan2, Sebastien Ourselin1

1BioMedia Lab, Autonomous Systems Laboratory, ICT Centre, CSIRO, Sydney, NSW, Australia; 2University of Sydney, Sydney, NSW, Australia

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                  1704.    Observation of Anisotropic Properties of Skeletal Muscle in MR Elastography Via a Needle Device

Queenie C. C. Chan1, Geng Li1, Richard L. Ehman2, Edward S. Yang1

1The University of Hong Kong, Pokfulam, Hong Kong, People’s Republic of China; 2Mayo Clinic and Foundation, Rochester, Minnesota, USA

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                  1705.    MR-Elastography Reveals Skeletal Muscle Elasticity Changes in Patients with Hypogonadism
                                Prior to Testosterone Substitution and After 6 Months

Katja Brauck1, Stefan Maderwald1, Craig Galban1, Burkhard Herrmann1, Frank Stock1, Mark Ladd1

1University Hospital Essen, Essen, NRW, Germany

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                  1706.    The Effects of Deoxyhemoglobin and Flow Rate on R2' in Hindlimb Perfused Skeletal Muscle

Otto Alexander Sanchez1, Bruce M. Damon1

1Vanderbilt University, Nashville, Tennessee, USA

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                  1707.    Dual Gradient-Echo Imaging of Ischemia/Reperfusion in Skeletal Muscle

Bruce M. Damon1, Jennifer L. Hornberger1, Jane A. Kent-Braun2

1Vanderbilt University, Nashville, Tennessee, USA; 2University of Massachusetts, Amherst, Massachusetts, USA

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                  1708.    Idiopathic Inflammatory Myositis: Analysis of Magnetic Resonance Imaging Using IDL to Enhance Diagnosis

Charles Edward Hutchinson1, Harriet Chaney1, Robert C. Cooper2, Judith E. Kilgallon3

1University of Manchester, Manchester, UK; 2Salford Royal Hospital NHS Trust, Salford, UK; 3Christie Hospital NHS Trust, Manchester, UK

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                  1709.    Fast Spatially Resolved Measurement of R2’ and R2 of Each Component of Cancellous Bone Marrow
                                and Correlation of R2’ with Trabecular Bone Volume Fraction (BVF)

Catherine E. Jones1, Jeremy F. Magland1, Aranee Techawiboonwong1, Felix W. Wehrli1

1University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

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                  1710.    Potential Metabolic Markers for Intervertebral Disc Pain

Kayvan Keshari1, John Kurhanewicz1, Serena Hu1, Thomas Link1, Jeffrey Lotz1, Sharmila Majumdar1

1University of California, San Francisco, San Francisco, California, USA

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                  1711.    Dynamic Contrast Enhanced MR Imaging and 1H MR Spectroscopy Study of Post Menopausal Osteoporosis

James Francis Griffith1, David Yeung1, Gregory E. Antonio1

1The Chinese University of Hong Kong, Shatin, Hong Kong, People’s Republic of China

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                  1712.    Magic Angle MR Microscopy and T2 Quantification of Intervertebral Discs
                                Highlights the 3-Dimensional Collagen Structure

Jeff Frank Dunn1, Tad Foniok2, John Robert Matyas1

1University of Calgary, Calgary, AB, Canada; 2National Research Council, Calgary, AB, Canada

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                  1713.    Apparent Diffusion Coefficient Measurement for Evaluation of Vertebral Normal Variations in the Lumbar Spine

Youichi Sato1, Eito Kozawa1, Naoko Nishi1, Takayuki Hoshino1, Atsuko Heshiki1

1Saitama Medical School, Moroyama-chou, Saitama, Japan

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                  1714.    Normal Variations in the Vertebral Appearrence on Opposed-Phase MRI: We Need to Know
                                Normal Bone Marrow Appearrence

Eito Kozawa1, Waka Mizukoshi1, Takayuki Hoshino1, Atsuko Heshiki1

1Saitama Medical School, Moroyama-chou, Saitama, Japan

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                  1715.    In Vivo MR T1rho Mapping in Lumbar Vertebral Discs at 3T: A Preliminary Study

Xiaojuan Li1, Eric T. Han2, Thomas M. Link1, Sharmila Majumdar1

1University of California at San Francisco, San Francisco, California, USA; 2GE Healthcare Global, Menlo Park, California, USA

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                  1716.    Characterization of Intervertebral Disc Degeneration with T1ń Imaging

Chenyang Wang1, Walter Witschey1, Wade Johannessen1, Sampreet Niyogi1, Ari Borthakur1, Dawn M. Elliott1, Ravinder Reddy1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA

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                  1717.    Improved Assessment of Degenerative Intervertebral Discs with a Novel Magic Echo Mapping Technique

Walter R.T. Witschey II1, C Wang1, Brian K. Bronzo1, Wade Johannessen1, Dawn M. Elliott1, Ravinder Reddy1

1University of Pennsylvania, Philadelphia, Pennsylvania, USAText Box:  

 

                  1718.    Quantitative 3D- T1ρ Weighted MRI of Lumbar Spine at 3.0T

Famory -. Niang1, Sait Kubilay Pakin1, Mark E. Schweitzer1, Ravinder R. Regatte1

1New York University School of Medicine, New York, New York, USA

Text Box:  

 

                  1719.    In Vivo Assessment of Human Lumbar Disc Degeneration

Ari Borthakur1, Joshua D. Auerbach1, Wade Johannessen1, Carol A. Dolinskas2, Richard A. Balderston2,

Dawn M. Elliott1, Ravinder Reddy1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Pennsylvania Hospital, Philadelphia, Pennsylvania, USA

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                  1720.    Quantitative Assessment of Clinical Stage of Aplastic Anemia by Using Dual Phase Chemichal Shift Sequence

Eito Kozawa1, Waka Mizukoshi1, Atsuko Heshiki1

1Saitama Medical School, Moroyama-chou, Saitama, Japan

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                  1721.    Diffusion Tensor Imaging of the Forearm's Nerves

Dan Stein1, Arnon Neufeld2, Moshe Graif2, Yaniv Assaf1, 2

1Tel Aviv University, Tel Aviv, Israel; 2Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

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                  1722.    Diffusion Weighted Magnetic Resonance Spectroscopy of Peripheral Nerve at 18.8T

Jacob Ellegood1, Ryan T. McKay1, Chris C. Hanstock1, Christian Beaulieu1

1University of Alberta, Edmonton, Alberta, Canada

 

 

                  1723.    Tendon Imaging Using 3D Ultrashort TE Scanning

Jürgen Rahmer1, Peter Börnert1, Clemens Bos2, Jan Groen2, Giel Mens2

1Philips Research Laboratories, Hamburg, Germany; 2Philips Medical Systems, Best, Netherlands

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                  1724.    Diffusion MRI of Denervated Skeletal Muscle for Early Diagnosis of Peripheral Nerve Injury

Eiko Yamabe1, Toshiyasu Nakamura1, Koichi Oshio1, Yoshito Kikuchi2, Hiroyasu Ikegami1, Yoshiaki Toyama1

1School of Medicine, Keio University, Tokyo, Japan; 2Saitama Municipal Hospital, Saitama, JapanText Box:  

 

                  1725.    Determination of Anisotropic Velocity Profiles in Muscle Using Wave-Guide Constrained
                                Magnetic Resonance Elastography

Anthony Joseph Romano1, Philip B. Abraham1, Stacie I. Ringleb2, Phillip J. Rossman2, Joseph A. Bucaro1,

Richard L. Ehman2

1Naval Research Laboratory, Washington, District of Columbia, USA; 2Mayo Clinic, Rochester, Minnesota, USA

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                  1726.    Fanctional Imaging of Muscle Contraction Caused by Electric Stimulation

Yasuharu Watanabe1, Keisaku Kimura2, Masahiro Umeda2, Ichio Aoki2, Masahiro Higuchi2, Chuzo Tanaka2,

Shoji Naruse3

1Meiji School of Oriental Medicine, Suita, Osaka, Japan; 2Meiji University of Oriental Medicine, Nantan, Kyoto, Japan; 3Radiology, Kyoto, Kyoto, JapanText Box:  

 

                  1727.    Skeletal Muscle Degeneration and Regeneration Following Femoral Artery Ligation in the Mouse,
                                as Monitored Using Diffusion Tensor Imaging

Anneriet M. Heemskerk1, Glenda S. van Bochove1, Maarten R. Drost2, Gustav J. Strijkers1, Klaas Nicolay1

1Eindhoven University of Technology, Eindhoven, Netherlands; 2Maastricht University, Maastricht, Netherlands

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                  1728.    Dynamic Changes in DTI Eigenvalues and Eigenvectors Following Ischemia-Induced Skeletal Muscle Damage

Anneriet M. Heemskerk1, Gustav J. Strijkers1, Glenda S. van Bochove1, Maarten R. Drost2, Klaas Nicolay1

1Eindhoven University of Technology, Eindhoven, Netherlands; 2Maastricht University, Maastricht, Netherlands

 

 

                  1729.    Diffusion Tensor MRI for the In Vivo Determination of Skeletal Muscle Architecture in Two Ankle Angles

Anneriet M. Heemskerk1, Gustav J. Strijkers1, Maarten R. Drost2, Klaas Nicolay1

1Eindhoven University of Technology, Eindhoven, Netherlands; 2Maastricht University, Maastricht, Netherlands

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                  1730.    Quantitative Characterization of Mouse Calf Muscle Degeneration After Left Sciatic Nerve
                                Axotomy with Magnetic Resonance Imaging

Jiangyang Zhang1, Gang Zhang1, Susumu Mori1, 2, Kazim A. Sheikh1

1Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 2Kennedy Krieger Institute, Baltimore, Maryland, USAText Box:  

 

                  1731.    Effect of Skeletal Muscle T1 Changes on the Determination of Perfusion by Arterial Spin Labelling
                                Combined to NMR Imaging

Céline Baligand1, Didier Bertoldi1, Claire Wary1, Pierre G. Carlier1

1Institut de Myologie, Paris, France

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                  1732.    Radiologic Evaluation of Hip Measurements: MR Versus X-Ray Correlation

Sarah Ann Shock1, Andy I. Abeles2, Mark E. Schweitzer1, Robert Meislin1, James Babb1, Charbel Isaak1

1NYU, New York, New York, USA; 2University of Missouri, Columbus, Missouri, USAText Box:  

 

                  1733.    The Study of Ulnar Variance with High-Resolution MRI: Correlation with Triangular
                                Fibrocartialge Complex and Cartilage of Ulnar Side of the Wrist

Hiroshi Yoshioka1, Toshiokazu Tanaka2, Teruko Ueno3, John A. Carrino1, Carl S. Winalski1, Philipp Lang1,

Barbara N. Weissman1

1Brigham and Women's Hospital, Boston, Massachusetts, USA; 2Mayo Clinic, Rochester, Minnesota, USA; 3Iwate Medical School, Morioka, Iwate, Japa

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                  1734.    The Value of MR Imaging Using Microscopy Coil in Evaluation of Finger Masses: Correlation
                                with Pathologic and Surgical Findings

Jung-Ah Choi1, In Sook Lee2, Joo Han Oh1, Heung Sik Kang1

1Seoul National University Bundang Hospital, Seongnam, Gyeongi-do, Republic of Korea; 2Pusan National University College of Medicine, Pusan, Republic of Korea

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                  1735.    Joint Arthrography with MRI Image Overlay: Porcine Trials

Gregory Scott Fischer1, Anton Deguet1, Csaba Csoma1, Russell H. Taylor1, Laura Fayad1, S James Zinreich1,

Gabor Fichtinger1

1Johns Hopkins, Baltimore, Maryland, USA

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                  1736.    Feasibility of MR Guided Direct Arthrography

Suzanne Wakeley1, Martin J. Graves1, Philip Bearcroft1, Richard T. Black1, Elzare van Rooyen1, David John Lomas1

1University of Cambridge & Addenbrooke's Hospital, Cambridge, UK

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                  1737.    High SNR, Microscopic Imaging of Skin Lesions

Stefan Maderwald1, Susanne C. Ladd1, Mark E. Ladd1, Frank Stock1, Thomas Paul1, Anja Liffers2, Jörg Barkhausen1, Thilo Gambichler2, Harald H. Quick1

1University Hospital Essen, Essen, Germany; 2Ruhr-University Bochum, Bochum, Germany

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                  1738.    Abnormal Post-Ischemic Reperfusion Patterns in the Skeletal Muscle of Serotonin Deficient Mice
                                Identified by Arterial Spin Labeling Coupled to SSFSE Imaging

Didier Bertoldi1, Yves Fromes2, Cécile Fligny3, Francine Cote3, Guilan Vodjdani3, Pierre G. Carlier1

1Institut de Myologie, Paris, France; 2Institut de myologie, Paris, France; 3UMR 7091, Paris, France

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                  1739.    Application of 1H and 31P Single Point Imaging (SPI) of Teeth Using Silent Gradients

Marco L.H. Gruwel1, Peter Latta1, Marta Tanasiewicz2, Vyacheslav Volotovskyy1, Milos Sramek3, Boguslaw Tomanek1

1NRC-CNRC, Winnipeg, MB, Canada; 2Silesia Medical Academy, Katowice, Poland; 3OAW Visualisierung, Vienna, Austria

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                  1740.    3D Visualisation of the Tooth Caries - Potential New Area for Biomedical Application of MRI

Wladyslaw Piotr Weglarz1, Marta M. Tanasiewicz2, Tomasz W. Kupka2, Marco LH Gruwel3, Cezary Przeorek4,

Andrzej Jasinski1, Boguslaw Tomanek3

1Institute of Nuclear Physics, Krakow, Poland; 2Medical University of Silesia, Bytom, Poland; 3NRC Institute of Biodiagnostics, Winnipeg, Manitoba, Canada; 4Comprehensive Cancer Centre, Gliwice, Poland

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                  1741.    NMR Study of Gallstones from Benign and Malignant Gallbladders

Madhulika Srivastava1, 2, G. A. Nagana Gowda2, Ajay Sharma3, Ashish Gupta2, V. K. Kapoor3, C. L. Khetrapal2

1Department of Surgery, Lucknow, Uttar Pradesh, India; 2Centre of Biomedical Magnetic Resonance, Lucknow, Uttar Pradesh, India; 3Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India


 

Cancer Models: Detection, Diagnoses, and Staging

Room 4E                    Tuesday 13:30 - 15:30

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                  1742.    Functional Colonoscopy Using Dark Lumen DCE-MRI

Christopher Chad Quarles1, James Oliver McIntyre1, David Lee Gorden1, Martin Lepage, 1,2, Thomas Edison Yankeelov1, Ronald R. Price1, Lynn M. Matrisian1, John Christopher Gore1

1Vanderbilt University, Nashville, Tennessee, USA; 2University Sherbrooke, Sherbrooke, QC, Canada

 

 

                  1743.    Tumor-Antigen Targeted Imaging of Pancreatic Adenocarcinoma

Zdravka Medarova1, Wellington Pham1, Young Kim1, Guangping Dai1, Anna Moore1

1Massachusetts General Hospital, Charlestown, Massachusetts, USA

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                  1744.    A Dendrimer Based Contrast Agent for MR Imaging of Her-2/neu Receptors by a Three-Step
                                Pretargeting Approach

Wenlian Zhu1, Baasil Okollie1, Zaver M. Bhujwalla1, Dmitri Artemov1

1Johns Hopkins University, Baltimore, Maryland, USAText Box:  

 

                  1745.    Characterization of Rat Glioma Models by Magnetic Resonance Angiography

Sabrina Doblas1, Yasvir Tesiram1, Debra Saunders1, Quentin Pye1, Preeti Kshirsagar1, Rheal A. Towner1

1Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA

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                  1746.    Dynamic Contrast Magnetic Resonance Imaging Detects Premalignant High-Grade
                                Dysplasia in Epithelial Carcinogenesis

Joel Richard Garbow1, John Engelbach1, Krista Olson1, Jeffrey Arbeit1

1Washington University, St. Louis, Missouri, USA

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                  1747.    Early Detection of Prostate Neoplasm Using Pixel-By-Pixel R1 Mapping Following Gd(ABE-DTTA)
                                Administration in TRAMP Mice

Pal Kiss1, Ada Elgavish1, Isam-Eldin A. Eltoum1, Pal Suranyi1, Huadong Zeng1, Tamas Simor1, Balazs Ruzsics1, Gabriel A. Elgavish1

1University of Alabama at Birmingham, Birmingham, Alabama, USAText Box:  

 

                  1748.    Improved Prostate Cancer Detection Using DCE-MRI and Probability Maps

Xinrui Huang1, Qiang Wang2, Yufeng Xu3, Xiaoying Wang3, Shanglian Bao1

1The Key Lab of Medical Physics and Engineering,Peking University, Beijing, People’s Republic of China; 2The Medical School of Peking University, Beijing, People’s Republic of China; 3The First Hospital of Peking University, Beijing, People’s Republic of China

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                  1749.    Tumor Growth with Anisotropic Diffusion

Ashok Kumar1, Alma Gregory Sorensen1

1Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA

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                  1750.    Longitudinal MR Studies of Human Mammary Carcinoma Cell Brain Metastasis in Nude Mice at 7 Tesla

Rui Simoes1, 2, Antonio Martinez3, Sebastián Cerdán4, Angels Sierra3, Carles Arús1

1Universitat Autňnoma de Barcelona, Barcelona, Spain; 2Universidade de Coimbra, Coimbra, Portugal; 3Institut de Recerca Oncolňgica, Barcelona, Spain; 4Instituto de Investigaciones Biomédicas Alberto Sols UAM-CSIC, Madrid, SpainText Box:  

 

                  1751.    High Field MR Imaging of Pre-Invasive Pancreatic Carcinoma in a Transgenic Mouse Model

Palamadai Nilakantan Venkatasubramanian1, Paul Grippo2, Richard Knop3, Alice Wyrwicz1

1ENH Research Institute, Evanston, Illinois, USA; 2Northwestern University School of Medicine, Chicago, Illinois, USA; 3Evanston Northwestern Healthcare, Evanston, Illinois, USA

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                  1752.    Characterization and Early Detection of Liver Metastasis by fMRI

Yifat Edrei1, Eitan Gross1, Eli Pikarsky1, Eithan Galun1, Rinat Abramovitch1

1Hadassah Hebrew University Medical Center, Jerusalem, Israel

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                  1753.    Semi-Automated Lymph Node Staging Using LN-MRI

Gozde Unal1, Greg Slabaugh1, Bernd Wachmann1, Thomas Fuchs1, Tong Fang1, Robert Krieg2, Ravi Seethamraju2, Mukesh Harisinghani3, Ralph Weissleder3

1Siemens Corporate Research, Princeton, New Jersey, USA; 2Siemens Medical Solutions, Erlangen, Germany; 3Massachusetts General Hospital, Boston, Massachusetts, USA

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                  1754.    Multiparametric Imaging of Tumor Boundaries Using Linear Discriminant Analysis

Marina Benito-Vicente1, Pilar López-Larrubia1, Laura Barrios2, Patricia Sanchez-García1, Sebastián Cerdán1,

María Luisa García-Martín1

1Instituto de Investigaciones Biomédicas “Alberto Sols” CSIC/UAM, Madrid, Spain; 2CSIC, Madrid, Spain

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                  1755.    Comparison of Spectral Spatial PRESS with TE Averaged PRESS in Breast Choline Detection

Fei Sun1, Lu Hong2, Guang Cao3

1GE Healthcare China, Beijing, People’s Republic of China; 2Tianjin Cancer Hospital, Tianjin, People’s Republic of China; 3GE Healthcare China, Hong Kong, People’s Republic of China

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                  1756.    Fatty Acid Speciation by NMR Spectroscopy and Potential Methods for Liver Cancer Diagnaosis

Yasvir A. Tesiram1, Debra Saunders1, Jeff Griffitts1, Rheal A. Towner1

1Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA

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                  1757.    1H-MR Spectroscopy of the Prostate at 3.0 T with a Phase-Array Surface Coil

Frank Traeber1, Nuschin Morakkabati-Spitz1, Ursula Jaeger1, Mike P. Wattjes1, Patrick Bastian1, Alexander Schmitz1, Jürgen Gieseke2, Okan Guer1, Wolfgang Block1, Renate Bloemer1, Hans H. Schild1

1University of Bonn, Bonn, Germany; 2Philips Medical Systems, Best, Netherlands

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                  1758.    Line Scan Echo Planar Spectroscopic Imaging of the Prostate at 3T: Feasibility Study

Yasushi Kaji1, Kagayaki Kuroda2, Ryo Sugihara1, Kazuro Sugimura1

1Kobe Univ. Graduate School of Medicine, Kobe, Hyogo, Japan; 2Institute of Biomedical Research and Innovation, Kobe, Hyogo, Japan

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                  1759.    Differentiation of Low from High Grade Oligodendrogliomas by 1H Magnetic Resonance
                                Spectroscopy Imaging and Perfusion Weighted Imaging

Sanjeev Chawla1, Sumei Wang1, John H. Woo1, Jiongjiong Wang1, Donald M. O' Rourke1, Kevin Judy1,

Michael S. Grady1, Ranald L. Wolf1, Elias R. Melhem1, Harish Poptani1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA

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                  1760.    Dynamic Contrast-Enhanced MR and Proton MR Spectroscopic Imaging in Localizing Prostate Cancer

Jurgen J. Futterer1, Tom W.J. Scheenen1, Stijn W.T.P.J. Heijmink1, Christina A. Hulsbergen-van de Kaa1,

J. Alfred Witjes1, Arend Heerschap1, Jelle O. Barentsz1

1UMCN, Nijmegen, Gld, Netherlands

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                  1761.    Imaging Findings of Castleman Disease of the Abdomen and Pelvis

Liangping Zhou1, Weijun Peng1, Peihua Wang1, Bei Zhang2, Yubao Guan3, Kangrong Zhou4

1Cancer Hosipital of Fudan University, Shanghai, People’s Republic of China; 2Shanghai Ruijin Hosipital, Shanghai, People’s Republic of China; 31stHospital of Guangzhou  College, Guangzhou, People’s Republic of China; 4Zhongshan Hosipital of Fudan University, Shanghai, People’s Republic of China

 

Cancer Models: Predicting and Monitoring Therapy Response with MRI

Room 4E                    Tuesday 13:30 - 15:30

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                  1762.    Characterization of the Tumor Micro-Environment After Administration of Glucocorticoids to
                                Understand Their Radiosensitization Effect

Nathalie Crokart1, Bénédicte F. Jordan1, Christine Baudelet1, Gregory O. Cron1, Julie Hotton1, Kim Radermacher1, Vincent Gregoire1, Nelson Beghein1, Philippe Martinive1, Olivier Feron1, Bernard Gallez1

1Université Catholique de Louvain, Brussels, B, Belgium

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                  1763.    Botulinum Toxin Potentiates Cancer Radiotherapy and Chemotherapy

Réginald Ansiaux1, Christine Baudelet1, Greg O.Cron1, Jérôme Segers1, Chantal Dessy1, Philippe Martinive1,

Julie De Wever1, Julien Verrax1, Valérie Wauthier1, Nelson Beghein1, Vincent Grégoire1, Pedro Buc Calderon1,

Olivier Feron1, Bernard Gallez1

1Catholic University of Louvain, Woluwe, Brussels, Belgium

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                  1764.    Botulinum Toxin Increases Tumor Uptake of Gemcitabine Chemotherapy as Measured with Fluorine Spectroscopy

Greg O. Cron1, Nelson Beghein1, Réginald Ansiaux1, Bernard Gallez1

1Catholic University of Louvain, Brussels, Belgium

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                  1765.    Blood Flow Increase in 9L Brain Tumors in Response toRadiation Therapy and Chemotherapy as
                                Detected by Arterial Spin Labeling MRI

Amandeep Salhotra1, Phillip Zhe Sun1, 2, Peter C.M. van Zijl1, 2, Zaver Bhujwalla1, Bachchu Lal2, John Laterra1, 2, Jinyuan Zhou1, 2

1Johns Hopkins University, Baltimore, Maryland, USA; 2KKI, Baltimore, Maryland, USA

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                  1766.    Carbogen Breathing Differentially Enhances Blood Plasma Volume and 5-Fluorouracil Uptake in
                                Two Murine Colon Tumor Models with Distinct Vascular Structures

Hanneke van Laarhoven1, Giulio Gambarota1, Jasper Lok1, Martin Lammens1, Yvonne Kamm1, Theo Wagener1, Cornelis Punt1, Albert van der Kogel1, Arend Heerschap1

1University Medical Centre Nijmegen, Nijmegen, Gld., Netherlands

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                  1767.    Application of Multiple-Quantum-Filtered 23Na MRI to Monitor Chemotherapeutic Response in RIF-1 Tumors

Andriy Babsky1, Hong Zhang1, Shahryar K. Hekmatyar1, Gary Hutchins1, Navin Bansal1

1Indiana University, Indianapolis, Indiana, USA

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                  1768.    Evolution of the Tumor Oxygenation and Perfusion at the Early Stage of the Treatment with SU5416,
                                an Inhibitor of Flk-1 Tyrosine Kinase

Réginald Ansiaux1, Christine Baudelet1, Greg O.Cron1, Philippe Martinive1, Julie De Wever1, Vincent Grégoire1, Olivier Feron1, Bernard Gallez1

1Catholic University of Louvain, Woluwe, Brussels, BelgiumText Box:  

 

                  1769.    Comprehensive Magnetic Resonance Monitoring of Tumoricidal Effect of a Vascular Targeting Agent
                                in a Rodent Liver Metastatic Model

Yicheng Ni1, Xihe Sun1, 2, Feng Chen1, 3, Frederik De Keyzer1, Vincent Vandecaveye1, Willy Landuyt1,

Paul Van Hecke1, Hide Bosmans1, Guy Marchal1

1University Hospital, Catholic University of Leuven, Leuven, B-3000, Belgium; 2Affiliated Hospital, Weifang Medical University, Weifang, Shandong, People’s Republic of China; 3Zhong Da Hospital, Southeast University, Nanjing, Jiangsu, People’s Republic of China

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                  1770.    Early Response Measurements of NGR-TNF Efficacy Using MR and Immunohistochemical Methods

Hanneke van Laarhoven1, Giulio Gambarota1, Cornelis Punt1, Jasper Lok1, Ilja Verhagen1, Angelo Corti2,

Salvatore Toma3, Corrado Gallo Stampino3, Albert van der Kogel1, Arend Heerschap1

1University Medical Centre Nijmegen, Nijmegen, Netherlands; 2San Raffaele H Scientific Institute, Milan, Italy; 3MolMed S.p.A, Milan, Italy

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                  1771.    TOOKAD Photodynamic Therapy of Orthotopic PC3-MM2  Prostate Tumors in Nude Rats :
                                Investigation Using  BOLD-MRI, Diffusion-Weighted-MRI and  Dynamic-Contrast Enhanced MRI

Dominique Blanc1, Henri Ficheux1, Nathalie Just2, Nicolas Guilbaud2

1NEGMA-LERADS, Magny-les-Hameaux, France; 2Oncodesign Biotechnology, Dijon, France

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                  1772.    MRI Assessment of a Treatment for Non-Small Cell Lung Cancer in a Mouse Model

Ruqayyah M. Al-Hashem1, Hongbin Ji2, Mitchell S. Albert1, Kwok-Kin Wong2, Yanping Sun1

1Brigham & Women's Hospital, Boston, Massachusetts, USA; 2Dana Farber Cancer Institute, Boston, Massachusetts, USA

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                  1773.    Ranpirnase-Induced Changes in Blood Flow, Lactate, and ATP Levels in A549 Human NSCLC
                                Measured by Noninvasive Near Infra-Red Spectroscopy and Magnetic Resonance Spectroscopy

Sergey Magnitsky1, Ulas Sunar1, Matthew Milkevitch1, Arjun G. Yodh1, Intae Lee1

1University of Pennsylvania, Philadelphia, PA 19104-6069, USA

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                  1774.    A 1H MRS Study of Tumour Overexpression of Dimethylarginine Dimethylaminohydrolase (DDAH)
                                and Response to Taxotere

Basetti Madhu1, Saira Ansari1, John R. Griffiths1, Guy St.J. Whitley1, Simon P. Robinson1

1St. George's, University of London, London, England, UK

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                  1775.    Real-Time Imaging of Emerging Resistance During Cancer Therapy

Kuei C. Lee1, Daniel E. Hall1, Benjamin A. Hoff1, Bradford A. Moffat1, Surabhi Sharma1, Thomas L. Chenevert1, Charles R. Meyer1, Wilbur R. Leopold2, Timothy D. Johnson1, Alnawaz Rehemtulla1, Brian D. Ross1

1University of Michigan Medical School, Ann Arbor, Michigan, USA; 2Molecular Imaging Research Preclinical Services, Ann Arbor, Michigan, USA

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                  1776.    The ADC Value in Esophageal Caners on Diffusion-Weighted MR Images for Predicting Effect
                                of Chemoradiotherapy

Takashi Koyama1, Shigeaki Umeoka1, Tsuneo Saga1, Ken Tamai1, Go Watanabe1, Masahiro Hiraoka1, Kaori Togashi1

1Kyoto University, School of Medicine, Kyoto, Japan

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                  1777.    In Vivo MR Diffusion Investigation of Murine Tumors with Bacteria Infiltration

Kaung-Ti Yung1, Xiangjin Song1, Gabrielle Ramus1, Vitaly Chibisov1, Qiuhong He1

1University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA




Clinical MRS in Cancer

Room 4E                    Tuesday 13:30 - 15:30

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                  1778.    Characterization of High Grade Gliomas Using TE-Averaged PRESS at 3 T

Yan Li1, Radhika Srinivasan1, Susan M. Chang1, Sarah J. Nelson1

1University of California, San Francisco, California, USA

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                  1779.    Quantitative SENSE Spectroscopy of Gliomas at 3T

Esin Ozturk-Isik1, 2, Albert P. Chen1, 2, Jason C. Crane1, Duan Xu1, Eric T. Han3, Daniel B. Vigneron1, 2,

Soonmee Cha1, Susan M. Chang1, Sarah J. Nelson1, 2

1University of California, San Francisco, California, USA; 2UCSF/UCB Joint Graduate Group in Bioengineering, San Francisco, California, USA; 3GE Healthcare Global Applied Science Laboratory, Menlo Park, California, USA

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                  1780.    Fast Nosologic Imaging of the Brain

Maarten De Vos1, Teresa Laudadio1, Arjan W. Simonetti1, Sabine Van Huffel1, Arend Heerschap2

1K.U.Leuven, Leuven, Belgium; 2U.M.C.Nijmegen, Nijmegen, Netherlands

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                  1781.    Enhanced  Detection of Glutamine (Gln) and Glutamate (Glu) with 1H MRS Using Single
                                Voxel STEAM: Their Potential to Stage Brain Tumors

Matthew R. Amans1, Quan Jiang2, Yang Xuan1, Shireen Hm-Meeran1, Lucia J. Zamorano1, Murali Guthikonda1, Geoffrey Barger1, Vivek Sehgal1, Jiani Hu1

1Wayne State University, Detroit, Michigan, USA; 2Henry Ford Hospital, Detroit, Michigan, USA

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                  1782.    Brain Tumour Diagnosis and Prognosis by In Vivo 1H MRS and Ex Vivo Metabolomic and
                                Genomic Data. A Prospective Study as Part of ETUMOUR (FP6-2002-LSH503094)

Daniel Monleon1, Carmen Martinez-Bisbal1, Beatriz Martinez-Granados1, Vicent Esteve1, Eva Pińero-Sagredo1,

Ruben Ferrer-Luna1, Manuel Mata2, Jose Piquer3, Luis Marti-Bonmati4, Bernardo Celda1

1Universitat de Valencia, Burjassot, Valencia, Spain; 2University of Valencia, Valencia, Spain; 3Hospital de la Ribera, Alzira, Valencia, Spain; 4Clinica Quiron, Valencia, Spain

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                  1783.    In Vivo MRS Metabolic Profiles of Human Brain Metastases from Different Primary Cancers

Torill Eidhammer Sjřbakk1, Roar Johansen1, Tone Frost Bathen1, Ursula Sonnewald1, Kjell Arne Kvistad2,

Steinar Lundgren, 12, Ingrid Susanne Gribbestad1

1Norwegian University of Science and Technology, Trondheim, Norway; 2St.Olavs University Hospital Trondheim, Trondheim, Norway

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                  1784.    Sequential MRSI and DWI Study for Early Assessment of Response of Breast Cancer
                                to Neo-Adjuvant Chemotherapy: A Pilot Study

K A. Danishad1, V Seenu1, S Roell2, M Vorbuchner2, N R. Jagannathan1

1All India Institute of Medical Sciences, New Delhi, Delhi, India; 2Siemens Medical Solutions, Erlangen, Germany

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                  1785.    Simultaneous Detection of Choline and Other Metabolites Using SEE-SelMQC for Spectroscopic
                                Imaging of Human Breast Cancer

Qiuhong He1, Xiaohong Joe Zhou2

1Univerisity of Pittsburgh, Pittsburgh, Pennsylvania, USA; 2University of Illinois Medical Center, Chicago, Illinois, USA

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                  1786.    MR-Determined Metabolic Phenotype of Breast Cancer Predicts Lymphatic Spread, Grade and Hormone Status

Tone Frost Bathen1, Line Rřrstad Jensen1, Beathe Sitter1, Hans Fjřsne2, Jostein Halgunset1, David E. Axelson3,

Ingrid Susanne Gribbestad1, Steinar Lundgren, 12

1NTNU, Trondheim, Norway; 2St. Olavs University Hospital, Trondheim, Norway; 3MRI_Consulting, Kingston, Ontario, Canada

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                  1787.    High-Resolution Magic Angle Spinning (HRMAS) 1H MRS Detects Biomarkers in Pancreatic Cancer

Haihui Cao1, 2, Gregory Y. Lauwers2, Carlos Fernandez-del Castillo2, Andrew L. Warshaw2, A. Aria Tzika1, 2

1Massachusetts General Hospital and Shriners Institute, Harvard Medical School, Boston, Massachusetts, USA; 2Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

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                  1788.    Potential of 3D 1H MRSI Localization of Prostate Cancer to Direct TRUS Guided Biopsy in Patients
                                with PSA 4 – 10 Ng/mL

 

Virendra Kumar1, N R. Jagannathan1, Rajeev Kumar1, S C. Das1, Lokesh Jindal1, Sanjay Thulkar1, S Dutta Gupta1,

S N. Dwivedi1, A K. Hemal1, N P. Gupta1

1All India Institute of Medical Sciences, New Delhi, Delhi, India

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                  1789.    1D High Resolution Magic Angle Spinning Total Correlation Spectroscopy of Prostate Cancer Tissues

Mark Gunnard Swanson1, Andrew S. Zektzer1, Kayvan R. Keshari1, Laura Tabatabai1, Thomas Butler1,

John Kurhanewicz1

1UCSF, San Francisco, California, USA

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                  1790.    Potential of 1H MR Spectroscopic Imaging to Predict Negative Biopsy in Men with PSA < 10 Ng/mL

Virendra Kumar1, Rajeev Kumar1, Lokesh Jindal1, Rishi Nayyar1, Sanjay Thulkar1, S Dutta Gupta1, S N. Dwivedi1,

A K. Hemal1, N P. Gupta1, N R. Jagannathan1

1All India Institute of Medical Sciences, New Delhi, Delhi, India

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                  1791.    3D 1H MRSI Based TRUS Guided Biopsies in Men with Suspected Prostate Cancer

Virendra Kumar1, N R. Jagannathan1, Rajeev Kumar1, Lokesh Jindal1, S C. Das1, Rishi Nayyar1, Sanjay Thulkar1,

S Dutta Gupta1, S N. Dwivedi1, A K. Hemal1, N P. Gupta1

1All India Institute of Medical Sciences, New Delhi, Delhi, India;

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                  1792.    Single Voxel and Chemical Shift Imaging (CSI) of Soft Tissue Sarcomas

Virendra Kumar1, Madhabanda Kar1, K A. Danishad1, S V.S Deo1, N K. Shukla1, U Sharma1, S Dattagupta1, S Dey1,

S Tulkar1, N R. Jagannathan1

1All India Institute of Medical Sciences, New Delhi, Delhi, India

 

Clinical Applications in Cancer

Room 4E                    Tuesday 13:30 - 15:30

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                  1793.    Multi-Contrast Whole-Body 2D Axial MR Imaging During Continuous Table Movement for Tumor Staging

Katja Brauck1, Michael Zenge1, Frank Stock1, Ladd Mark1, Florian Vogt1, Joerg Barkhausen1

1University Hospital Essen, Essen, NRW, Germany

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                  1794.    3D MR Sialography  as a Tool to Visualize and Investigate Radiation-Induced Changes to the
                                Salivary Glands and Ducts in Patients

Eleftheria Astreinidou1, C.P.J Raaijmakers1, J. Roesink1, C Terhaard1, L. W. Bartels1

1University Medical Center, Utrecht, Netherlands

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                  1795.    Three-Dimensional Proton MR Spectroscopic Imaging of Human Breast Lesions

Michael A. Jacobs1, 2, Mari Smith3, Nagi Khouri1, David A. Bluemke1, Peter B. Barker3

1Johns Hopkins School of Medicine, Baltimore, Maryland, USA; 2Sidney Kimmel Dept of Oncology, Baltimore, Maryland, USA; 3Kennedy Krieger Institute, Baltimore, Maryland, USA

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                  1796.    Evaluation of CADstreamTM for Serial Automated Breast Tumor Volume Measurements in Patients
                                Undergoing Neoadjuvant Chemotherapy for Breast Cancer

Bonnie N. Joe1, Alexander Urioste2, Kiarash Vahidi1, Jessica Gibbs1, Evelyn Proctor1, Zakar Siraj1, Ying Lu1,

Nola Hylton1

1University of California, San Francisco, San Francisco, California, USA; 2University of California, San Diego, San Diego, California, USA

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                  1797.    Characterisation of Breast Tumors with a Model-Independent Analysis of Bolus-Tracking MRI

Smitha Makkat1, Steven Sourbron1, Vally Dewilde1, Filip De Ridder1, Rob Luypaert1, Tadeusz Stadnik1, Johan De Mey1

1Vrije Universiteit Brussel, Brussels, Belgium

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                  1798.    Comparison of Whole Body MRI and Whole Body PET-CT for Staging of Advanced
                                Bronchial Carcinoma – Initial Results

Christian Plathow1, Susanne Eschmann1, Philipp Aschoff1, Vanessa Heinrich1, Jürgen Schaefer1, Claus Claussen1, Thomas Hehr1, Christina Pfannenberg1 , Heinz-Peter Schlemmer1

1Eberhard-Karls University, Tuebingen, Baden-Wuerttemberg, Germany

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                  1799.    Usefulness of Diffusion-Weighted MR Image in Detecting Pancreas Cancer: Comparative Analyses
                                with T1, T2-Weighed MR Images

Noriaki Muraoka1, Hirohiko Kimura1, Hidemasa Uematsu1, Yasuhiro Fujiwara1, Isao Yamaguchi1, Harumi Itoh1

1University of Fukui, Fukui, Japan

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                  1800.    High-B-Value Diffusion-Weighted MR Imaging of Gastric Cancer: By Segmented Breath-Hold Technique

Xiao Peng Zhang1, Lei Tang2, Ying Shi Sun1, Fei Sun3

1Beijing Cancer Hospital & Peking University School of Oncology, Beijing, People’s Republic of China; 2Beijing Cancer Hospital, School of Oncology, Peking University, Beijing, People’s Republic of China; 3MR Modality, GE Healthcare, China, Beijing, People’s Republic of China

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                  1801.    Abdominal Imaging with Extended Field of View in Rectal Cancer Using a Continuously Moving Table:
                                A Feasibility Study

Gregor Sommer1, Ute Ariane Ludwig1, Hans-Peter Fautz1, Oliver Schäfer1

1University Hospital Freiburg, Freiburg, Germany

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                  1802.    Multi-Parametric MR Imaging of Prostate Cancer at 3T

Albert P. Chen1, 2, Joonmi Oh1, Eric T. Han3, Duan Xu1, 2, John Kurhanewicz1, 2, Daniel B. Vigneron1, 2

1UCSF, San Francisco, California, USA; 2UCSF/UCB, San Francisco, California, USA; 3GE Healthcare, Menlo Park, California, USA

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                  1803.    Metabolic Profiling of Preinvasive and Invasive Cervical Cancer Using 1H and 31P Magic Angle Spinning MRS

Sonali S. De Silva1, Geoffrey S. Payne1, Patrick Soutter2, Nandita M. Desouza1

1Institute of Cancer Research, Sutton, Surrey, UK; 2Hammersmith Hospital, London, UK

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                  1804.    Deformable Registration of Abdominal Mion-Enhanced MR Images for Presurgical and Radiotherapy
                                Planning of Lymph Nodes

Fred S. Azar1, Christophe Chefdhotel1, Ravi T. Seethamraju2, Mukesh G. Harisinghani3

1Siemens Corporate Research, Princeton, New Jersey, USA; 2Siemens Medical Solutions, Boston, Massachusetts, USA; 3Massachusetts General Hospital, Boston, Massachusetts, USA

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                  1805.    MR Imaging of Bone Tumors - A Pictorial Review

Guenther K. Schneider1, Peter M. Fries1, Alexander Massmann1, Dieter Kohn2, Klaus Remberger1, Roland M. Seidel3, Roland M. Seidel3

1UniversityHospital of Saarland, Homburg, Saar, Germany; 2Saarland University Hospital, Homburg, Saar, Germany; 3Saarland UniversityHospital, Homburg, Saar, Germany