Neonatal Brain

                  2059.    Lateral Ventricular Size in Extremely Premature Infants: 3D MRI Confirms 2D Ultrasound Measurements

Johan Bengtsson¹, Sandra Horsch¹, Hugo Lagercrantz¹, Zoltán Nagy¹, Anders Nordell¹, Ulrika Ådén¹, Bo Nordell¹, Mats Blennow¹

¹Karolinska University Hospital, Stockholm, Sweden

                  2060.    Diffusion Tensor Imaging of the Developing Visual Cortex and Visual White Matter
                                Pathways in Premature Newborns

Robert Thomas Held¹, Pratik Mukherjee², Srivathsa Veeraraghavan², A James Barkovich², Daniel B. Vigneron, ¹²

¹UCSF/UCB, San Francisco, California, USA; ²University of California, San Francisco, California, USA

                  2061.    Defining Normal and Abnormal DTI Parameters in Premature Newborns

Srivathsa C. Veeraraghavan¹, Steven P. Miller¹, Pratik Mukherjee¹, Natalie N. Charlton¹, Duan Xu¹,

Anthony James Barkovich¹, Daniel B. Vigneron¹

¹University of California, San Francisco, California, USA

                  2062.    High Resolution Diffusion Tensor Imaging of the Corpus Callosum in the Preterm Brain at 3 Tesla

Mustafa Anjari¹, Latha Srinivasan¹, David J. Larkman¹, Joanna M. Allsop¹, Julie Fitzpatrick¹, Frances M. Cowan¹, Joseph V. Hajnal¹, Mary A. Rutherford¹, A David Edwards¹, Serena J. Counsell¹

¹Hammersmith Hospital, Imperial College London, London, UK

                  2063.    Impact of Preterm Birth on Hippocampal Structure Utilizing Volumetric MRI Techniques

Deanne Kim Thompson¹, Stephen J. Wood, Gary F. Egan¹, Lex W. Doyle², Simon K. Warfield³,

Gregory A. Lodygensky⁴, Peter J. Anderson⁵, Terrie E. Inder⁴

¹Howard Florey Institute, University of Melbourne, Melbourne, VIC, Australia; ²Royal Women's Hospital, University of Melbourne, Melbourne, VIC, Australia; ³Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; ⁴St. Louis Childrens Hospital, Washington University in St Louis, St Louis, Missouri, USA; ⁵Murdoch Childrens Research Instititue, Melbourne, VIC, Australia

                  2064.    Volumetric and Diffusion Analysis of the Neonatal Brain

Jonathan Paul Dyke¹, Linda A. Heier¹, Aziz M. Ulug¹, Jeffrey M. Perlman¹, Maricor Castillo¹

¹Weill Cornell Medical College, NY, USA

                  2065.    Easy and Effective Acoustic Noise Protection in Neonatal MRI

Marcus Lundh¹, Anders Nordell¹, Johan Bengtsson¹, Zoltan Nagy¹, Sandra Horsch¹, Ulrika Adén¹, Bo Nordell¹

¹Karolinska University Hospital, Stockholm, Sweden

                  2066.    Determining the Most Consistent Method for MRI Hippocampal Volumetry in Infants at Term

Deanne Kim Thompson¹, Stephen J. Wood, Terrie E. Inder², Simon K. Warfield³, Lex W. Doyle⁴, Gary F. Egan¹

¹Howard Florey Institute, University of Melbourne, Melbourne, VIC, Australia; ²St Louis Children's Hospital, Washington University in St Louis, St Louis, Missouri, USA; ³Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; ⁴Royal Women's Hospital, University of Melbourne, Melbourne, VIC, Australia

                  2067.    Quantitative DTI Assessment of Periventricular White Matter Changes in Neonatal Meningitis

Richa Trivedi¹, Amit Gupta², G K. Malik², Rakesh Kumar Gupta¹, Khader M. Hasan³, Kashi Nath Prasad¹,

Ponnada A. Narayana³

¹Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; ²King George’s Medical University, Lucknow, Uttar Pradesh, India; ³University of Texas Medical School at Houston, Houston, Texas, USA

                  2068.    Water Mapping of the Whole Brains of Infants Using an FSE Sequence at 3.0 T

Zhengchao Dong¹, ², Feng Liu¹, ², Alayar Kangarlu¹, ², Bradley Peterson¹, Bradley Peterson¹, ²

¹Columbia University, New York, New York, USA; ²New York State Psychiatric Institute, New York, New York, USA

                  2069.    Brain-Water ADC and 31P MRS Imaging Metabolite Ratios and Intracellular PH
                                in a Piglet Model of Transient Hypoxia-Ischemia

Alan Bainbridge¹, Osuke Iwata², Enrico De Vita¹, Daniel A. West², John S. Thornton³, Satchi Iwata²,

Nichola J. Robertson², Ernest B. Cady¹

¹University College London Hospitals NHS Foundation Trust, London, UK; ²University College London, London, UK; ³National Hospital for Neurology and Neurosurgery, London, UK


 

MRS/MRI of Neuropsychiatric Disease

                  2070.    Region and Gender Specific Neurochemical Alterations and Sleep Deprivation in
                                Major Depressive Episodes

Harald Murck¹, Mirjam I. Schubert¹, Dagmar Schmid¹, Petra Schuessler¹, Axel Steiger¹, Dorothee P. Auer¹

¹Max Planck Institute of Psychiatry, Munich, Bavaria, Germany

                  2071.    Lower GPC Compounds in the Hippocamps and Higher GPE in the Putamen/thalamus
                                Region in Depressed Patients Detected by 3D ³¹P RINEPT MRSI

Gabriele Ende¹, Tim Wokrina¹, Sigi Walter¹, Helga Welzel¹, Christine Kief¹, Traute Demirakca¹, Marco Ulrich¹, Alexander Sartorius¹, Fritz A. Henn¹

¹Central Institute of Mental Health, Mannheim, Germany

                  2072.    Frontal and Occipital Lobe GABA Changes in Depression, Measured with 1H-MRS

C. John Evans¹, Marzena Wylezinska¹, Zubin Bhagwagar¹, Peter Jezzard¹, Akeem Sule¹, Sudhakar Selvaraj¹,

Paul Matthews¹, Philip Cowen¹

¹University of Oxford, Oxford, Oxfordshire, UK

                  2073.    Proton Spectroscopy Study of Adolescent Depression

Vilma Gabby¹, David Hess¹, James S. Babb¹, Oded Gonen²

¹New York University, School of Medicine, New York, New York, USA; ²New York University, New York, USA

                  2074.    MRI Morphometry of the Brain in a Longitudinal Study of Depression

Jamila Ahdidan¹, Lars Kroloekke Hviid¹, Kim Mouridsen², Barbara Ravnkilde¹, Anders Bertil Rodell³,

Raben Rosenberg¹, Poul Videbech¹

¹University Psychiatric Hospital in Aarhus, Risskov, Denmark; ²CFIN, Aarhus, Denmark; ³General Hospital of Aarhus, Aarhus, Denmark

                  2075.    Treatment of Adolescent Bipolar Depression with Lithium: Effects on Brain MyoInositol
                                Levels Measured by Proton MR Spectroscopy

Kim M. Cecil¹, Melissa P. DelBello², Nick C. Patel³, Caleb M. Adler², Stephen M. Strakowski²

¹Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA; ²University of Cincinnati College of Medicine, Cincinnati, Ohio, USA; ³University of Cincinnati College of Pharmacology, Cincinnati, Ohio, USA

                  2076.    Comparison of 1D and 2D MR Spectroscopy in Bipolar Depression

Shida Banakar¹, ², June Watzl¹, Nader Binesh², Mark Frye², Albert M. Thomas²

¹LABIOMED at Harbor-UCLA, Torrance, California, USA; ²UCLA School of Medicine, Los Angeles, California, USA;

                  2077.    Hippocampal Neurochemical Findings in Medication-Free, Euthymic Bipolar Disorder:
                                1H MRSI Study

Wen-Jang Chu¹, Stephen M. Strakowski¹, Hoby P. Hetherington², Xin Wang¹, Cal M. Adler¹, Mellissa P. DelBello¹, John N. Adams¹, Neil P. Mills¹, Yun Gao¹, Kelly B. Javis¹, Jing-Huei Lee¹

¹Univ. of Cincinnati, Cincinnati, Ohio, USA; ²Albert Einstein College of Medicine, Bronx, New York, USA

                  2078.    Global Gray/White Matter Ratio and Gray Matter Volume Reflect Abnormal Aging
                                Neurodevelopment in Treatment Naive Schizophrenics

Su Lui¹, Luo Ouyang², Wei Deng¹, Tao Li¹, Hong Yang¹, Hehan Tang¹, Lijun Jiang¹, Xiaoqi Huang¹, Bin Song¹, Xiangping Zhou¹, Sumner Maclean¹, ³, Vanessa Sluming⁴, Qiyong Gong¹, ⁴

¹West China Hospital of Sichuan University, Chengdu, Sichuan, People’s Republic of China; ²University of Electronic Science and Technology of China, Chengdu, Sichuan, People’s Republic of China; ³Universitatsklinikum, Goettingen, Germany; ⁴University of Liverpool, Liverpool, UK

                  2079.    Cortical Disorganization in Brodmann Areas 9, 46 and 32 in Schizophrenia:
                                Evidence from Brodmann-Based MRI Morphometry

Vaibhav A. Diwadkar¹, ², Jeffrey J. Nutche², Rhonda El-Sheikh¹, Serguei Fedorov¹, Debra M. Montrose²,

Matcheri S. Keshavan¹, ²

¹Wayne State University School of Medicine, Detroit, Michigan, USA; ²University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

                  2080.    Working Memory Dysfunction with fMRI Task and Gray Matter Difference in Schizophrenia
                                Patients Using Voxel Based Morphometry

Rahyeong Juh¹, ², Min Ying Su¹, Chang Uk Lee², Tae Suk Suh², Orhan Nalcioglu¹

¹University of California, Irvine, California, USA; ²Catholic University of Korea, Seoul, Republic of Korea

                  2081.    2D and 3D RINEPT {¹H}-³¹P-MRSI in the Human Brain and Its Possible Application to Schizophrenia

Tim Wokrina¹, Marco Ulrich¹, Gabriele Ende¹

¹Central Institute of Mental Health, Mannheim, Germany

                  2082.    High Energy Phosphate Abnormalities Normalize After Antipsychotic Treatment in Schizophrenia:
                                A Longitudinal 31P MRS Study of Basal Ganglia

Jayakumar Peruvumba Narayan¹, B N. Gangadhar¹, G Venkatasubramanian¹, M S. Keshavan²

¹National Institute of Mental Health & Neurosciences, Bangalore, Karnataka, India; ²Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA

                  2083.    Assessing the Effect of Comorbidity in Attention-Deficit/Hyperactivity Disorder (ADHD)
                                Using In Vivo ³¹P Spectroscopy

Jeffrey A. Stanley¹, Matcheri S. Keshavan¹, Heidi Kipp², Erika Greisenegger², Kanagasabai Panchalingam³,

Jay W. Pettegrew³, Oscar G. Bukstein³

¹Wayne State University School of Medicine, Detroit, Michigan, USA; ²Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA; ³University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

                  2084.    Elevated Brain Lactate Response During Visual Stimulation in Panic Disorder

Richard J. Maddock¹, Michael H. Buonocore¹, Linda E. Copeland¹, Anne L. Richards¹, Shawn P. Lavoie¹

¹University of California Davis, Sacramento, California, USA

                  2085.    Positive Correlation of Glycerophosphocholine with Alcohol Consumption in Frontal White Matter
                                of Light Social Drinkers Revealed by 3D ³¹P MRSI Using RINEPT Editing

Tim Wokrina¹, Traute Demirakca¹, Matthias Ruf¹, Marco Ulrich¹, Sigrid Walter¹, Helga Welzel¹, Gabriele Ende¹

¹Central Institute of Mental Health, Mannheim, Germany

                  2086.    Brain Volume Measurements Correlate with Impulsivity and Aggression

Renee Ochs¹, ², Ying Wu¹, ², Carly Demopoulos¹, ², Rachel Scheidegger¹, ², Robert R. Edelman¹, ², Ann B. Ragin¹, ²

¹Northwestern University, Chicago, Illinois, USA; ²Evanston Northwestern Healthcare, Evanston, Illinois, US

                  2087.    fMRI-Guided Spectroscopy for Evaluation of Speech-Related Brain Areas in Neuropsychiatry

Peter Vermathen¹, Claudia Ehrlich², Daniela Hubl², Andrea Federspiel², Thomas Dierks², Chris Boesch¹,

Roland Kreis¹

¹University Berne, Berne, Switzerland; ²University Hospital of Clinical Psychiatry, Berne, Switzerland

Advanced Imaging in Brain Tumors

                  2088.    Plasticity Changes as Reorganization of Pre-Motor Cortex in Lower Limb Amputees: A VBM Study

Juan Ignacio Romero-Romo¹, ², Corica Rodgers³, Juan José Ortiz², Leopoldo Gonzalez², Angel Romero²,

Fernando Alejandro Barrios²

¹SESEQ, Querétaro, QRO, Mexico; ²Universidad Nacional Autónoma de México, Querétaro, QRO, Mexico; ³University of California, Irvine, California, USA

                  2089.    Structural Abnormalities in Posterior Fossa Brain Tumor Survivors:
                                A Voxel-Based Morphometry Study Based on Free-Form Deformation

Yong Zhang¹, ², Ping Zou¹, Raymond K. Mulhern¹, Robert J. Butler³, Robert J. Ogg¹

¹St. Jude Children's Research Hospital, Memphis, Tennessee, USA; ²University of Tennessee Health Science Center, Memphis, Tennessee, USA; ³Oregon Health and Science University, Portland, Oregon, USA

                  2090.    Quantitative Analysis of Gd Enhancement Histogram Tails Predicts Transformation in Low Grade Gliomas

Paul S. Tofts¹, Chris E. Benton¹, Rimona S. Weil¹, Daniel J. Tozer¹, Daniel Altmann¹, H Rolf Jager¹,

Adam D. Waldman¹, ², Jeremy H. Rees¹

¹UCL, London, UK; ²Charing Cross Hospital, London, UK

                  2091.    Using RCBV and CBF to Distinguish Radiation Necrosis from Tumor Recurrence in Malignant Gliomas

Rebecca Ann Lund¹, Scott D. Rand¹, H G. Krouwer¹, Chris J. Schultz¹, Kathleen M. Schmainda¹

¹Medical College of Wisconsin, Milwaukee, Wisconsin, USA

                  2092.    fMRI in Patients with Brain Tumors: Descriptive Serial Cases of Cognitive Function in
                                Pre and Post Surgical Conditions

Erika Aguilar¹, Maria De Iturbe¹, Karla Becerril¹, Priscila Rojas¹, Ana Luisa Sosa¹, Sergio Gomez LLata¹,

Ulises Garcia¹, Perla Salgado¹, Jorge Paz¹, Fernando Barrios², Erick Pasaye¹

¹Instituto Nacional de Neurología y Neurocirugía "MVS", Mexico, DF, Mexico; ²Instituto de Neurobiología, Juriquilla, Queretaro, Mexico

                  2093.    Assessing Changes in Tumor Vascular Function Using DCE-MRI: A Tale of Two Analysis Algorithms

Srikanth Mahankali¹, Qing Yuan¹, Alfred WK Yung¹, Edward Franklin Jackson¹

¹The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Multiple Sclerosis: Grey and White Matter Lesions

                  2094.    Detection of Subpial Cortical Demyelinating Lesions in Multiple Sclerosis In Vivo

Jacqueline Tien Hsiang Chen¹, D. Louis Collins¹, Harold L. Atkins², Mark S. Freedman², Douglas L. Arnold¹

¹Montreal Neurological Institute/McGill University, Montreal, QC, Canada; ²The Ottawa Hospital-General Campus, Ottawa, ON, Canada

                  2095.    Abnormalities of Deep Gray Matter Perfusion in Multiple Sclerosis:
                                Dynamic Susceptibility Contrast Perfusion MRI at 3.0 T

Matilde Inglese¹, Sun-Jung Park¹, Glyn Johnson¹, James S. Babb¹, Hina Jaggi¹, Joseph Herbert¹, Robert I. Grossman¹

¹New York University, New York, New York, USA

                  2096.    Imaging Cadavers - 'cold Brain' MRI Effects and Noninvasive Diffusion Thermometry of the CSF

Paul S. Tofts¹, Daniel J. Tozer¹, David G. MacManus¹, Klaus Schmierer¹, Nick C. Fox¹

¹University College London, London, UK

                  2097.    In Vivo Visualization of Multiple Sclerosis Cortical Lesions by High Resolution MRI at 3T

Francesca Bagnato¹, Lalith Talagala², Vasiliki Ikonomidou², Alessandro Calabrese², Fernanda Tovar-Moll²,

Annie W. Chiu², Marco Riva², Mary Ehrmantraut², Joan M. Ohayon², Henry F. McFarland²

¹NIB, Bethesda, Maryland, USA; ²NINDS / NIH, Bethesda, Maryland, USA

                  2098.    Imaging Cortical Lesions at Standard and High Field-Strength (1.5T and 4.7T):
                                Post-Mortem MRI and Histopathology

Jeroen J. G. Geurts¹, Erwin Blezer², Hugo Vrenken¹, Annette van der Toorn², Chris H. Polman¹, Jonas A. Castelijns¹, Petra J. W. Pouwels¹, Lars Bö¹, Frederik Barkhof¹

¹VU University Medical Center, Amsterdam, Noord-Holland, Netherlands; ²University of Utrecht, Utrecht, Netherlands

                  2099.    A Voxel-Based Morphometric Analysis of Clinically Isolated Syndrome Patients

Mason Shieh¹, Daniel Pelletier¹, Kathleen Garrison¹, Darin Okuda¹, Roland G. Henry¹

¹University of California at San Francisco, San Francisco, California, USA

                  2100.    Texture Response of Deep Gray Matter in Patients with Multiple Sclerosis Treated with Minocycline

Yunyan Zhang¹, Luanne M. Metz¹, Hongmei Zhu², Voon Wee Yong¹, J Ross Mitchell¹

¹University of Calgary, Calgary, Alberta, Canada; ²York University, Toronto, Ontario, Canada

                  2101.    Quantitative T1 Measurements Suggest Sex-Dependent Gray Matter Involvement in MS

Jeffrey M. Njus¹, Leif E. Vigeland¹, Xin Li¹, ², Charles S. Springer¹, ², Maria Taylor³, Frank W. Telang²,

Patricia K. Coyle³, William D. Rooney¹, ²

¹Oregon Health and Science University, Portland, Oregon, USA; ²Brookhaven National Laboratory, Upton, New York, USA; ³Stony Brook University, Stony Brook, New York, USA

                  2102.    MRI Evidence for a Strong Relationship Between Total Cerebral White-Matter Lesion Load and
                                Clinical Disability in Patients with Multiple Sclerosis

Zografos Caramanos¹, Sridar Narayanan¹, Simon James Francis¹, André Luiz Mendes Matos¹,

Maria Carmela Tartaglia¹, Yves Lapierre¹, Douglas Lorne Arnold¹

¹Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada

                  2103.    Extensive T2* Heterogeneity in White Matter Studied by High Resolution MRI at 7T

Tie-Qiang Li¹, Alan Koretsky¹, Peter van Gelderen¹, Hellmut Merkle¹, Lalith Talagala¹, Jeff Duyn¹

¹NIH, Bethesda, Maryland, USA

                  2104.    Quantitative Multi-Slice Mapping of the Myelin Water Fraction Using Multi-Compartment Analysis
                                of T2* Relaxation at 3T

Yiping P. Du¹, Renxin Chu¹, Mark S. Brown¹, Bette K. Kleinschmidt-DeMasters¹, Jack H. Simon¹

¹University of Colorado Health Sciences Center, Denver, Colorado, USA

                  2105.    Normal-Appearing White Matter Changes Vary with Distance to Lesions in Multiple Sclerosis

Hugo Vrenken¹, Jeroen J.G. Geurts¹, Dirk L. Knol¹, Chris H. Polman¹, Jonas A. Castelijns¹, Petra J.W. Pouwels¹, Frederik Barkhof¹

¹VU University Medical Center, Amsterdam, Netherlands

                  2106.    The Early MS Pathology in the Corpus Callosum by Atrophy, Magnetization Transfer and
                                Diffusion Tensor Measures at 3T in Patients with a Clinically Isolated Syndrome and a Positive MRI

Jack H. Simon¹, Mark Brown¹, David E. Miller¹, Jeffrey Bennett¹, John Corboy¹, Deb Singel¹

¹University of Colorado Health Sciences Center, Denver, Colorado, USA

                  2107.    Registration and Subtraction of 2D-T2SE Images in a Routine Multicentre
                                Multiple Sclerosis (MS) Trial Setting

Bastiaan Moraal¹, Dominik S. Meier², Hugo Vrenken¹, Peter A. Poppe¹, Ronald A. van Schijndel¹, Petra Jan Willem Pouwels¹, Charles R G Guttmann², Frederik Barkhof¹

¹VU Medical Center, Amsterdam, Netherlands; ²Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

                  2108.    Semi-Automated Method for Quantifying and Localizing White Matter Hyperintensities on MR Images

Minjie Wu¹, Caterina Rosano¹, Meryl Butters¹, Ellen Whyte¹, Ryan Crooks¹, Carolyn Cidis Meltzer¹,

Charles F. Reynolds III¹, Howard Jay Aizenstein¹

¹University of Pittsburgh, Pittsburgh, Pennsylvania, USA

                  2109.    Identification of Abnormal White Matter in Multiple Sclerosis

Kishore Venkata Mogatadakala¹, Sushmita Datta¹, Aziz Hatim Poonawalla¹, Khader M. Hasan¹, Jerry S. Wolinsky¹, Ponnada A. Narayana¹

¹University of Texas Medical School at Houston, Houston, Texas, USA

                  2110.    Is a Two-Pool MT Model Valid in Tissues with Multicomponent T2?

Sharon Portnoy¹, Greg Jan Stanisz²

¹University of Toronto, Toronto, ON, Canada; ²Sunnybrook & Womens' CHSC, Toronto, ON, Canada

                  2111.    Corpus Callosum Partitioning Schemes and Their Effect on Callosal Morphometry

Charlotte Ryberg¹, Mikkel Bille Stegmann², Karl Sjöstrand², Egill Rostrup³, Franz Fazekas⁴, Frederik Barkhof⁵, Gunhild Waldemar¹

¹Memory Disorders Research Unit, Copenhagen, Denmark; ²Informatics and Mathematical Modelling, Kongens Lyngby, Denmark; ³Danish Reseach center for Magnetic Resonance, Copenhagen, Denmark; ⁴Medical University, Graz, Austria; ⁵VU Medical Center, Amsterdam, Netherlands

                  2112.    In-Vivo 3D Multi-Component T2-Relaxation Measurements for Quantitative Myelin Imaging at 3T

Burkhard Mädler¹, ², Alex L. MacKay²

¹UBC Hospital, Vancouver, BC, Canada; ²University of British Columbia, Vancouver, BC, Canada

                  2113.    Pattern of Hemodynamic Impairment in Multiple Sclerosis: Dynamic Susceptibility
                                Contrast Perfusion MRI at 3 T

Sumita Adhya¹, Glyn Johnson¹, Joseph Herbert¹, James S. Babb¹, Hina Jaggi¹, Robert I. Grossman¹, Matilde Inglese¹

¹New York University, New York, New York, USA

                  2114.    Diffusion Modeling Using Bayesian Probability Theory Applied to Imaging of Multiple Sclerosis

Joshua S. Shimony¹, Adrian A. Epstein¹, Christopher D. Kroenke¹, Jeffrey J. Neil¹, Anne H. Cross¹, Yvette I. Sheline¹, Abraham Z. Snyder¹, G Larry Bretthorst¹

¹Washington University Medical School, St. Louis, Missouri, USA

                  2115.    Minocycline Impedes the Evolution of Gd-Enhancing Lesions Into Black Holes in Patients with
                                Multiple Sclerosis

Yunyan Zhang¹, Luanne M. Metz¹, Voon Wee Yong¹, J Ross Mitchell¹

¹University of Calgary, Calgary, Alberta, Canada

                  2116.    Application of Single-Slab 3D-FLAIR, 3D-DIR and 3D-T2, Compared to 2D Dual-Echo T2,
                                in Multiple Sclerosis Patients

Bastiaan Moraal¹, Petra Jan Willem Pouwels¹, Hugo Vrenken¹, Charles R G Guttmann², Dominik S. Meier²,

Ronald A. van Schijndel¹, Jeroen J G Geurts¹, Frederik Barkhof¹

¹VU Medical Center, Amsterdam, Netherlands; ²Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

fMRI in Animals

                  2117.    Quantifying the BOLD Contribution in CBV-Weighted fMRI at 9.4T

Hanbing Lu¹, Leah Gitajn¹, William Rea¹, Yihong Yang¹, Elliot A. Stein¹

¹National Institute on Drug Abuse, Baltimore, Maryland, USA

                  2118.    Dynamic fMRI Acquisition of BOLD, RCBV, CBF, and Hypercapnic Reactivity for RCMRO2
                                Calculation During Rat Forelimb Stimulation

Young Ro Kim¹, George Dai¹, Emiri Tejima², Joseph B. Mandeville¹, Bruce R. Rosen¹

¹Athinoula Martinos Center for Biomedical Imaging/ Massachusetts General Hospital, Charlestown, Massachusetts, USA; ²Neuroprotection Research laboratory/ Massachusetts General Hospital, Charlestown, Massachusetts, USA

                  2119.    MRI Evidence of Resting State Connectivity in Rodent Brain

Kathleen Anne Williams¹, ², Scott J. Peltier, ¹², Stephen M. LaConte, ¹², Shella Dawn Keilholz¹, ²

¹Georgia Institute of Technology, Atlanta, Georgia, USA; ²Emory University, Atlanta, Georgia, USA

                  2120.    fMRI of the Rat’s Whisker-To-Barrel Pathway

Ian Mark Devonshire¹, Jason Berwick¹, Paul G. Overton¹, John E. Mayhew¹, Nikos G. Papadakis¹

¹University of Sheffield, Sheffield, UK

                  2121.    Imaging Dynamic Neural Network in Rat Brains Using BOLD fMRI

Tsukasa Nagaoka¹, ², Naoyuki Miyasaka, ²³, Richard P. Kennan², Seiji Ogawa², ⁴, Timothy Q. Duong¹

¹Emory University, Atlanta, Georgia, USA; ²Albert Einstein College of Medicine, Bronx, New York, USA;
³Tokyo Medical and Dental University, Bunkyo, Tokyo, Japan; ⁴Ogawa Laboratories for Brain Function Research, Shinjuku, Tokyo, Japan

                  2122.    Stimulus Frequency Dependence of the Relationship Between BOLD Signal and
                                Somatosensory Evoked Potential in Rat Cortex

Ikuhiro Kida¹, Mamoru Tamura¹, Toru Yamamoto¹

¹Hokkaido University, Sapporo, Hokkaido, Japan

                  2123.    Subcortical Forepaw Stimulation fMRI Activations in Awake Rats

Qiang Shen¹, Nanna Sulai¹, Timothy Q. Duong¹

¹Emory Unviersity, Atlanta, Georgia, USA

                  2124.    Distinct Characteristics of Brain Activity in Cat V1 and LGN in Response to Flicking and Grating
      Visual Stimuli: A fMRI Study at 9.4T

Xiao-Hong Zhu¹, Nanyin Zhang¹, Yi Zhang¹, Wei Chen¹

¹CMRR, Department of Radiology, University of Minnesota Medical School, Minneapolis, Minnesota, USA

                  2125.    Study of Correlation Between Brain Activity and ATP Metabolic Rates by Means of ³¹P Magnetization
                                Transfer and Electroencephalograph Measurement

Fei Du¹, Yi Zhang¹, Michael Friedman¹, Nanyin Zhang¹, Xiao-Hong Zhu¹, Kamil Ugurbil¹, Wei Chen¹

¹Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA

                  2126.    Functional Magnetic Resonance Imaging of the Rat Spinal Cord After Peripheral Nerve Injury

Katarzyna Majcher¹, Boguslaw Tomanek², ³, Andrzej Jasinski¹, ⁴, Tadeusz Foniok², Dave Kirk³, Dave Rushforth², Ursula I. Tuor², ³, Grzegorz Hess⁵

¹Institute of Nuclear Physics, PAS, Krakow, Poland; ²Institute for Biodiagnostics (West), NRC, Calgary, Alberta, Canada;
³Experimental Imaging Centre, University of Calgary, Calgary, Alberta, Canada; ⁴Pedagogical University, Krakow, Poland; ⁵Institute of Pharmacology, PAS, Jagiellonian University, Krakow, Poland

                  2127.    Functional Imaging of Cat Spinal Cord by CBV-Weighted fMRI

Fuqiang Zhao¹, Changfeng Tai¹, Jicheng Wang¹, Ping Wang¹, James R. Roppolo¹, William C. de Groat¹,

Seong-Gi Kim¹

¹University of Pittsburgh, Pittsburgh, Pennsylvania, USA

                  2128.    Comparison of Neural Activity in the Rat Spinal Cord Using fMRI and Field Potentials
                                During Noxious Electrical Stimulation of the Hind Paw

Jane Lawrence¹, ², Phillip F. Gardiner¹, Kalan R. Gardiner¹, Patrick W. Stroman, ¹³, Kris L. Malisza, ¹²

¹University of Manitoba, Winnipeg, Manitoba, Canada; ²National Research Council Institute for Biodiagnostics, Winnipeg, Manitoba, Canada;
³Queens University, Kingston, Ontario, Canada

                  2129.    Neural Basis of Unconditional Fear: Perfusion and Functional Imaging in Aging
                                Rat Bed Nucleus of the Stria Terminalis

Wei Chen¹, Young Kim², Karl F. Schmidt¹, Feng Luo¹, Mathew Brevard¹, Jean King¹

¹University of Massachusetts Medical School, Worcester,,Massachusetts, USA; ²MGH/MIT/HMS, Charlestown, Massachusetts, USA

                  2130.    Imaging Fear Stress Responses in Monkeys

Josie A. Harder¹, ², Timothy S. Garelick¹, Wei Chen¹, Jean A. King¹

¹UMass Medical School, Worcester, Massachusetts, USA; ²University of Bradford, Bradford, UK

                  2131.    Functional (BOLD) MRI in Zebra Finch to Investigate the Capacity of Specific Brain Regions
                                to Segregate Meaningful Auditory Signals from a Noisy Background

Tiny Boumans¹, Clémentine Vignal², ³, Alain Smolders¹, Marleen Verhoye¹, Johan Van Audekerke¹, Nicolas Mathevon³, Annemie Van der Linden¹

¹University of Antwerp, Antwerp, Belgium; ²Université Jean Monnet, Saint-Etienne, France; ³Université Paris XI, Orsay & LBA,
Université Jean Monnet, Saint-Etienne, France

                  2132.    Functional MRI of the Songbird Zebra Finch at 3 Tesla

Henning U. Voss¹, Kristen Maul², Douglas Ballon¹, Ofer T. Tchernichovski², Santosh A. Helekar³

¹Cornell University, New York, New York, USA; ²CUNY, New York, New York, USA; ³University of Houston, Houston, Texas, USA

                  2133.    Quantitative MRI of Cerebral Blood Flow in the Non-Human Primate

Paul A. Greenberg¹, Joanna E. Perthen¹, Anna L. Quijada¹, David J. Dubowitz¹

¹University of California San Diego, La Jolla, California, USA

                  2134.    High Spatial Resolution fMRI Mapping of Digit Topography and the Funneling Illusion
                                in SI Cortex of the Anesthetized Squirrel Monkey

Gregory Harrison Turner¹, Li Min Chen¹, Robert M. Friedman¹, John C. Gore¹, Anna W. Roe¹, Malcolm J. Avison¹

¹Vanderbilt University, Nashville, Tennessee, USA

                  2135.    Perfusion-Based fMRI in the Monkey Brain at 7T: Investigations of CASL Parameters

Anne Catherin Zappe¹, Hellmut Merkle², Josef Pfeuffer¹, ³, Nikos k. Logothetís¹

¹Max Planck Institute, Tuebingen, Germany; ²NIH/NINDS, Bethesda, Maryland, USA; ³Siemens Medical Solutions, Erlangen, Germany

                  2136.    Discordant Responses to Cocaine in CBF and CBV: Implications for PhMRI CMRO2 Assessment

Feng Luo¹, Karl F. Schmidt¹, Craig F. Ferris¹, Timothy Q. Duong²

¹UMass, Worcester, Massachusetts, USA; ²Emory University, Atalanta, Georgia, USA

                  2137.    Characterizing Alcohol-Induced Changes in Forebrain Activity in Awake Rats
      Using PhMRI and Assessing Brain Tissue Alcohol Pharmacokinetics Using Proton MR Spectroscopy

Feng Luo¹, Zhixin Li¹, Steven Treistman¹, Craig F. Ferris¹

¹University of Massachusetts, Worcester, Massachusetts, USA

                  2138.    A Multimodality Investigation of Cerebral Haemodynamics and Autoregulation in PhMRI

Alessandro Gozzi¹, Laura Ceolin¹, Adam Schwarz¹, Torsten Reese¹, Simone Bertani¹, Angelo Bifone¹

¹Centre of Excellence for Drug Discovery, Psychiatry, GlaxoSmithKline, Verona, Italy

                  2139.    Mapping Neural Activities of Area Postrema and Nucleus Tractus Solitarius in Awake
                                Rats Using Pharmacological MRI: Relevance as a Potential Biomarker for Detecting
                                Drug-Induced Emesis

Chih-Liang Chin¹, Gerard B. Fox¹, Vincent P. Hradil¹, Mark A. Osinski¹, Steve P. McGaraughty¹, Pamela D. Skoubis¹, Bryan F. Cox¹, Yanping Luo¹

¹Abbott Laboratories, Abbott Park, Illinois, USA

                  2140.    Application of Functional Magnetic Resonance Imaging to the Study of 5-HT2C
                                Neurotransmission in Rat Brain

Jennifer Ann Stark¹, Karen E. Davies¹, Shane McKie¹, Steve R. Williams¹, Simon M. Luckman¹

¹University of Manchester, Manchester, UK