fMRI: Measurement Techniques

Room 4E                    Thursday 13:30 - 15:30

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                  2801.    A New Method to Record 2D- Movement Kinematics During Functional Magnetic
                                Resonance Imaging (fMRI)

Tammar Kushnir1, Bjoern Hauptmann2, Ronen Sosnik3, Oded Smikt3, Eli Okon3, Tamar Flash3, Avi Karni, 14

1The Chaim Sheba Medical Center, Tel Hashomer, Israel; 2University Berlin, Berlin, Germany; 3The Weizmann Institute of Science, Rehovot, Israel; 4Haifa University, Haifa, Israel

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                  2802.    Characterization and Suppression of System Noise Due to Scanner Instability in fMRI Using a
                                SMART PHANTOM BOLD Simulator

Yu Li1, Qun Zhao2, Mark Limkeman1, Tim Conway2, Keith D. White2, Keith McGregor2, Bruce Crosson2

1Invivo Diagnostic Imaging, Gainesville, Florida, USA; 2R&D Brain Rehabilitation Research Center, Gainesville, Florida, USA

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                  2803.    Reduced fMRI Signal Sensitivity in Motor Areas When Cued by MRI-Compatible Apparatuses

Hsin-Mei Chen1, Wan-Chun Kuan1, Yau-Yau Wai1, 2, Yung-Liang Wan1, 2, Ho-Ling Liu1, 2

1Chang Gung Univ., Taoyuan, Taiwan; 2Chang Gung Memorial Hospital, Taoyuan, Taiwan

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                  2804.    A New Stimulus for Isolating Optokinetic Eye Movement from Smooth Pursuit

Caroline K.L. Schraa-Tam1, Aad van der Lugt1, Marion Smits1, Maarten A. Frens1, Philippus C.A. van Broekhoven1, Josef N. van der Geest1

1ErasmusMC, Rotterdam, ZH, Netherlands

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                  2805.    Evaluation of a Two Compartment Gel Phantom for fMRI

Anders Nilsson1, Anthony Brian Waites1, Peter Mannfolk1, Johan Olsrud1

1Lund University, Lund, Sweden

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                  2806.    BOLD Phantom Investigations of the Relationship Between Blood Oxygenation, Flow Variation and
                                Intra- And Extra-Vessel Signal Change

Lan Jiang1, Roderick McColl1, Ralph P. Mason1

1UT Southwestern Medical Center, Dallas, Texas, USA

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                  2807.    Improved Design for Absolute Skin Conductance Response Measurement During Motor fMRI

Bradley J. MacIntosh1, 2, Richard Mraz1, Vladimir Verpakhovski, Simon J. Graham1, 2

1Imaging Research, Sunnybrook & Women's CHSC, Toronto, ON, Canada; 2University of Toronto, Toronto, ON, Canada

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                  2808.    Predictive Eye Estimation Regression (PEER) for Simultaneous Eye Tracking and fMRI

Stephen Michael LaConte1, Scott J. Peltier1, Keith A. Heberlein1, Xiaoping P. Hu1

1Emory University/Georgia Tech, Atlanta, Georgia, USA

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                  2809.    Recording of Ultrafast (600-Hz) EEG Oscillations with Amplitudes in the Nanovolt Range
                                    During fMRI- Acquisition Periods

Petra Ritter1, Frank Freyer1, Robert Becker1, Kimitaka Anami2, Gabriel Curio1, Arno Villringer1

1Berlin Neuroimaging Center, Berlin, Germany; 2National Center Hospital for Mental, Nervous, and Muscular Disorders, Tokyo, Japan

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                  2810.    Failure to Detect Magnetic Source Dephasing Corresponding to ERP Generation

Lin Tang1, James Christopher Gatenby1, Malcolm J. Avison1, John C. Gore1

1Vanderbilt University Institute of Imaging Science, Nashville, Tennessee, USA

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                  2811.    Using MR Magnitude Imaging to Determine the Spatial Distribution of the Changes of
                                Magnetic Field Induced by Sub-μA Electric Current

Ruiwang Huang1, Oleg Posnansky1, Avdo Celik1, NJ Jon Shah1

1Research Centre Juelich, Juelich, Germany

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                  2812.    BOLD Sensitivity in Multiecho Sequences

Penny Anne Gowland1, Richard William Bowtell1

1Unversity of Nottingham, Nottingham, UK

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                  2813.    On the Effect of Flow and Modest Diffusion Weighting in fMRI

Maarten Versluis1, 2, Hans Hoogduin1

1University Medical Center Groningen, University of Groningen, Groningen, Netherlands; 2Philips Medical Systems, Best, Netherlands

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                  2814.    Determination of Acoustic Noise Characteristics and Development of Silent EPI for
                                Auditory fMRI

Sebastian Schmitter1, Michael Amann1, Lothar Rudi Schad1

1Deutsches Krebsforschungszentrum, Heidelberg, Germany

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                  2815.    Frequency Stabilization Using Finite Impulse Response Filtering for BOSS fMRI at 3T

Ming-Long Wu1, Teng-Yi Huang2, Pei-Hsin Wu1, Ming-Chung Chou1, 3, Cheng-Yu Chen3, Hsiao-Wen Chung1, 3

1National Taiwan University, Taipei, Taiwan; 2National Taiwan University of Science and Technology, Taipei, Taiwan; 3Tri-Service General Hospital, Taipei, Taiwan

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                  2816.    Transient State BOSS fMRI for a Further Increase in Sensitivity

Pei-Hsin Wu1, Ming-Long Wu1, Teng-Yi Huang2, Hsiao-Wen Chung1, 3

1National Taiwan University, Taipei, Taiwan; 2National Taiwan University of Science and Technology, Taipei, Taiwan;
   3
Tri-Service General Hospital, Taipei, Taiwan

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                  2817.    Parallel Imaging in Functional MRI: Comparison of Spiral SENSE and GRAPPA
                                and of Calibration Update Schemes

YoonChung Kim1, Douglas C. Noll1

1University of Michigan, Ann Arbor, Michigan, USA

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                  2818.    Feasibility of High Resolution 3D fMRI with Whole Brain Coverage

Yanle Hu1, Gary H. Glover1

1Stanford University, Stanford, California, USA

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                  2819.    Partial K-Space Acquisition Method for Improved SNR Efficiency and
                                Temporal Resolution in 3D fMRI

Yanle Hu1, Gary H. Glover1

1Stanford University, Stanford, California, USA

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                  2820.    Doubling EPI Resolution by Acquiring Two K-Space Lines Per Readout Gradient
                                Reversal Using TRAIL

Andrew Nicholas Priest1, 2, Enrico De Vita, 23, Roger John Ordidge3

1University Hospital Hamburg-Eppendorf, Hamburg, Germany; 2UCL Hospitals NHS Trust, London, UK;
   3
University College London, London, UK

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                  2821.    Isotropic, High-Resolution fMRI at 7T Using 3D Stack-Of-Segmented EPI

Karla L. Miller1, Graham C. Wiggins2, Christopher J. Wiggins2

1Oxford University, Oxford, UK; 2Massachusetts General Hospital, Charlestown, Massachusetts, USA

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                  2822.    Echo Train Shifted Multi-Echo FLASH for Functional MRI of the Human Brain at
                                Ultra-High Spatial Resolution

Dirk Voit1, Jens Frahm1

1Biomedizinische NMR Forschungs GmbH, Goettingen, Germany

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                  2823.    Effects of Local Susceptibility Gradients on Spiral K-Space Trajectory and
                                Effective Echo–Time (TEeff)

Sumati Krishnan1, Douglas C. Noll1

1University of Michigan, Ann Arbor, Michigan, USAText Box:  

 

                  2824.    Counterbalancing Mismatched Magnetization Differences in Functional
                                    Arterial Spin Labeling

Yi-Ching Lynn Ho1, Esben Thade Petersen1, Xavier Golay1

1National Neuroscience Institute, Singapore, Singapore

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                  2825.    Echo Time Dependence of Basal Ganglia Activation at 3T During Motor Task

Stephane Lehericy1, 2, Kamil Ugurbil2, Pierre-Francois Van de Moortele2

1University Pierre et Marie Curie, Paris, IDF, France; 2University of Minnesota, Minneapolis, Minnesota, USA

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                  2826.    Magnetic Field Effect of Neuronal Currents on MRI: A Snail Ganglia Study

Tae S. Park1, Soo Yeol Lee1, Ji-Ho Park1, Min Hyoung Cho1, Byung Hee Han1, Sang Yeon Lee1

1Kyung Hee University, Yongin, Kyungki, Republic of Korea

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                  2827.    Theoretical Modeling of MRI Signal Changes Induced by Neuronal Magnetic Fields

Yiqun Xue1, Jinhu Xiong1

1University of Iowa, Iowa City, Iowa, USA

 

 

 

fMRI Noise and Artifact Compensation

Room 4E                    Thursday 13:30 - 15:30

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                  2828.    Improved Sensitivity of Spinal fMRI by Using Physiological Recordings in General
                                Linear Model Analysis

Patrick W. Stroman1

1Queen's University, Kingston, Ontario, Canada

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                  2829.    A Bootstrap Method for Removing Aliased Cardiac and Respiratory Effects in
                                Volumetric Resting State Connectivity Data

Mark J. Lowe1, Ken E. Sakaie1

1Cleveland Clinic Foundation, Cleveland, Ohio, USA

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                  2830.    Efficacy of Data-Driven Respiration Compensation Methods in fMRI Data at 1.5T

Shuowen Hu1, Akshay D. Kothari1, Thomas M. Talavage1

1Purdue University, West Lafayette, Indiana, USA

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                  2831.    Functional MRI of the Human Amygdala Avoiding Susceptibility Artefacts

Carmen Morawetz1, Claudia Lange2, Petra Holz1, Jürgen Baudewig1, Godehard Weniger2, Eva Irle2, Peter Dechent1

1MR-Research in Neurology and Psychiatry, Medical Faculty, Georg-August-University, Göttingen, Germany;
2
Department of Psychiatry and Psychotherapy, Medical Faculty, Georg-August-University, Göttingen, Germany

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                  2832.    Calibration of fMRI by Simulating BOLD Contrast in the Living Human Brain

Qun Zhao1, Keith D. White1

1University of Florida, Gainesville, Florida, USA

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                  2833.    Realistic Computer Generated fMRI Phantoms with Motion Correlated Susceptibility Artifacts

Ning Xu1, Yong Li1, J Michael Fitzpatrick1, Benoit M. Dawant1, Victorial L. Morgan1, David R. Pickens1

1Vanderbilt University, Nashville, Tennessee, USA

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                  2834.    Complex Activation Suppresses Venous BOLD in GE-EPI fMRI Data

Daniel B. Rowe1, Andrew S. Nencka1

1Medical College of Wisconsin, Milwaukee, Wisconsin, USA

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                  2835.    Test-Retest Reliability of fMRI Using SmartPhantom

Qun Zhao1, 2, Keith D. White1, 2, Tim Conway1, 2, Keith McGregor1, Bruce Crosson1, 2

1University of Florida, Gainesville, Florida, USA; 2VA Medical Center, Gainesville, Florida, USAText Box:  

 

                  2836.    Application of Distortion Correction Procedures to Spin-Echo EPI for fMRI
                                Studies in the Temporal Lobe

Karl Vincent Embleton1, Matthew A. Lambon Ralph1, Geoff J. M. Parker1

1University of Manchester, Manchester, UKText Box:  

 

                  2837.    Local Dynamic Shimming for Slice-Wise Image Acquisition

Jung-Jiin Hsu1, Gary H. Glover1

1Lucas Center for Imaging, Stanford University School of Medicine, Stanford, California, USA

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                  2838.    Dynamic Updates of R2* and Field Map in fMRI Using a Spiral-In Quick-Spiral-Out
                                K-Space Trajectory

Valur Olafsson1, Jeffrey A. Fessler1, Douglas C. Noll1

1The University of Michigan, Ann Arbor, Michigan, USA

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                  2839.    Double-Sampled EPI in fMRI: A Ghost-Free Acquisition Method with Inherent
                                Field Map Correction Capability

Yi-Ru Lin1, 2, Shang-Yueh Tsai1, Teng-Yi Huang3, Ming-Long Wu1, Cheng-Yu Chen4, Hsiao-Wen Chung1, 4,

Nan-kuei Chen2, Kenneth Kwong5

1National Taiwan University, Taipei, Taiwan; 2Brigham and Women's Hospital - Harvard Medical School, Boston, Massachusetts, USA;
3
National Taiwan University of Science and Technology, Taipei, Taiwan; 4Tri-Service General Hospital, Taipei, Taiwan;
5
MGH-HMS-MIT Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA

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                  2840.    Quantification of Motion-Related Artifacts in  Simulated fMRI Data Using ICA

Ivana Drobnjak1, Christian F. Beckmann1, Mark Jenkinson1

1University of Oxford, Oxford, UK

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                  2841.    Detection and Correction of Motion-Induced Susceptibility Changes in fMRI Time
                                Series of the Alert  Monkey

Josef Pfeuffer1, 2, Thomas Steudel1, Hellmut Merkle3, Nikos K. Logothetis1

1MPI Biol. Cybernetics, Tuebingen, D, Germany; 2Siemens Medical Solutions, Erlangen, D, Germany; 3NIH/NINDS, Bethesda, Maryland, USA

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                  2842.    An Improved ICA Filter for Motion and Ballistocardiogram Artefacts in EEG
                                Recorded in the MR Scanner

Richard Andrew J. Masterton1, 2, David F. Abbott1, Steve Fleming1, Graeme D. Jackson1, 2

1Brain Research Institute, Melbourne, Victoria, Australia; 2University of Melbourne, Melbourne, Victoria, Australia

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                  2843.    Constrained ICA–based Ballistocardiogram and Electrooculogram Artifacts
                                Removal from EEG Signals Acquired Inside MRI

T. Rasheed1, T.-S. Kim1, Y.-K. Lee1, M. H. In1, W. H. Lee1, S. Y. Lee1, S. Y. Lee1

1Kyung Hee University, Yongin, Gyeonggi, Republic of KoreaText Box:  

 

                  2844.    BOLD Baseline 'activity' of Auditory Cortex During Silence

Iain D. Wilkinson1, Mike D. Hunter1, Simon B. Eickhoff2, Thomas WR Miller1, Thomas F. Farrow1, Peter WR Woodruff1

1University of Sheffield, Sheffield, South Yorkshire, UK; 2Institut for Medicine (IME), Research Center Juelich, Germany

 

fMRI Data and Statistical Analysis Method

Room 4E                    Thursday 13:30 - 15:30

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                  2845.    Sparse PCA a New Method for Unsupervised Analyses of fMRI Data

Karl Sjöstrand1, 2, Torben E. Lund2, Kristoffer H. Madsen, 1,2, Rasmus Larsen1

1Technical University of Denmark, Copenhagen, Denmark; 2Copenhagen University Hospital, Hvidovre, Denmark

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                  2846.    Accurate Localization of Functional Brain Activity Using Structure Adaptive Smoothing

Karsten Tabelow1, Jörg Polzehl1, Volodia Spokoiny1, Jonathan P. Dyke2, Linda A. Heier2, Henning U. Voss2

1Weierstrass Institute for Applied Analysis and Stochastics, Berlin, Germany;
2
Weill Medical College of Cornell University, New York, New York, USA

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                  2847.    Temporal Clustering Analysis: 3D Versus 2D Approaches in Functional MRI Studies

Xia Zhao1, Jie Tang2, Jia-Hong Gao1

1University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA;
2
Shenzhen Sinorad Medical Electronics Inc., Shenzhen, Guangdong, People’s Republic of China

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                  2848.    Multisubject Fuzzy Cluster Analysis of Functional MRI

Hesamoddin Jahanian1, 2, Seyyed Mohammad Shams2, Gholam Ali Hossein-Zadeh2, Hamid Soltanian-Zadeh1, 2

1Image Analysis Lab. Radiology Dept., Henry Ford Health System, Detroit, Michigan, USA;
2
Control and Intelligent Processing Center of Excellence, University of Tehran, Tehran, IranText Box:  

 

                  2849.    Exploring Spatiotemporal Pattern of Human Motor Cortex from fMRI by
                                Self-Clustering Independent Components with Partner Matching

Zhishun Wang1, Bradley S. Peterson1

1Columbia University and NYSPI, New York, New York, USA

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                  2850.    Multivariate Analysis of Resting State fMRI in Major Depression Using SeedPLS

Richard Cameron Craddock1, Svetlana Ye Masalovich2, Scott J. Peltier3, Xiaoping Hu3, Helen S. Mayberg2

1Georgia Institute of Technology, Atlanta, Georgia, USA; 2Emory University, Atlanta, Georgia, USA;
3
Georgia Institute of Technology/Emory University, Atlanta, Georgia, USA

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                  2851.    2dTCA for Detection of Irregular, Transient fMRI Activation

Victoria L. Morgan1, Yong Li1, Bassel Abou-Khalil1

1Vanderbilt University, Nashville, Tennessee, USA

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                  2852.    Independent Component Analysis in the Presence of Noise in fMRI

Dietmar Cordes1, Rajesh Nandy2

1University of Washington, Seattle, Washington, USA; 2UCLA, Los Angeles, California, USA

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                  2853.    fMRI Data Analysis by Means of Locally Linear Embedding

Peter Mannfolk1, Anthony Waites1, 2, Anders Nilsson1, Johan Olsrud1

1Lund University Hospital, Lund, Sweden; 2Brain Research Institute, Melbourne, Australia

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                  2854.    Nonparametric Mixture Modeling for Mapping of Brain Activation
                                Using Functional MRI Data

Rajesh Ranjan Nandy1, Dietmar Cordes2

1University of California, Los Angeles, California, USA; 2University of Washington, Seattle, Washington, USA

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                  2855.    Correlation Analysis of Functional Magnetic Resonance Imaging Data
                                Using FPGA Hardware

Markus Gipp1, Daniel Gembris1, Gerhard Lienhart1, Andreas Kugel1, Reinhard Männer1

1Universität Mannheim, Mannheim, Germany

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                  2856.    Distinguishing Robust Brain Activations Using Consistency Maps

Epifanio Bagarinao1, Kayako Matsuo2, Toshiharu Nakai2, Yoshio Tanaka1

1National Institute of Advanced Industrial Science and Technology, Tsukuba City, Ibaraki, Japan;
2
National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

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                  2857.    Wavelet-Based Statistical Analysis of fMRI Activation Images

Radu Mutihac1

1University of Bucharest, Bucharest, RomaniaText Box:  

 

                  2858.    Statistical Inference for Wavelet-Denoised Statistical Parametric Maps

 

Ryali Srikanth1, Ramon Casanova1, Paul J. Laurienti1, Ann M. Peiffer1, Joseph A. Maldjian1

1Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA

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                  2859.    Dynamic Monitoring of the Brain Activation Under Visual Stimulation Using fMRI -
                                The Advantage of a Sliding Window Analysis

Toshiharu Nakai1, Epifanio Bagarinao2, Kayako Matsuo1, Yuko Ohgami3, Chikako Kato4

1National Center for Geriatrics and Gerontology, Ohbu, Aichi, Japan; 2AIST, Tsukuba, Ibaragi, Japan; 3Ochanomizu University Graduate School of Humanitics and Science, Bunkyo-ku, Tokyo, Japan; 4Toyohashi Sozo College, Toyohashi, Aichi, JapanText Box:  

 

                  2860.    Time Course Analysis of T-Values in fMRI of Tool-Use Gestures with and Without Real Tools

Kayako Matsuo1, Epifanio Tila Bagarinao2, Yuko Ohgami3, Toshiharu Nakai1

1National Center for Geriatrics and Gerontology, Obu, Aichi, Japan; 2National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan; 3Ochanomizu University, Bunkyo-ku, Tokyo, JapanText Box:  

 

                  2861.    The Degree of Bilateral Organization of the Motor Areas Under Unimanual Motor Execution -
                                A Correlation Analysis Approach Using Dynamic Monitoring of T-Statistics

Toshiharu Nakai1, Epifanio Bagarinao2, Kayako Matsuo1, Yuko Ohgami3, Chikako Kato4

1National Center for Geriatrics and Gerontology, Ohbu, Aichi, Japan; 2AIST, Tsukuba, Ibaragi, Japan;
3
Ochanomizu University Graduate School of Humanitics and Science, Bunkyo-ku, Tokyo, Japan; 4Toyohashi Sozo College, Toyohashi, Aichi, Japan

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                  2862.    Functional MRI Incorporating Information on Voxel-Wise Tissue Volume Fractions

Yihong Yang1, Wang Zhan1, Hong Gu1, Elliot A. Stein1

1National Institute on Drug Abuse, NIH, Baltimore, Maryland, USAText Box:  

 

                  2863.    Jackknife Assessment of Individual Subject Effects on a Mixed-Effect Group
                                Level fMRI Analysis

Pradeep Chilakamarri Venkat1, Tom Johnstone1, Andy Alexander1, Terry Oakes1

1University of Wisconsin-Madison, Madison, Wisconsin, USAText Box:  

 

                  2864.    Comparison of the Signal-To-Noise Sensitivity of Different False
                                Discovery Rate Methods

Murali Murugavel1, John M. Sullivan1, Karl G. Helmer1

1Worcester Polytechnic Institute, Worcester, Massachusetts, USA

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                  2865.    Modified Weisskoff Test for Assessing fMRI Stability

Hans Hoogduin1, Peter Koopmans1, Remco Renken1

1University Medical Center Groningen, University of Groningen, Groningen, Netherlands

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                  2866.    Dotslashen: A Bayesian Decision Support System for fMRI Clinical Investigation

Ricardo Z.N. Vêncio1, 2, Liana Guerra Sanches1, Anita Taub1, Carolina Araújo1, Marcelo Maria Felix1,

Griselda Esther Jara Garrido1, Carlos Alberto Bragança Pereira2, Edson Amaro Jr. 1

1Hospital Israelita Albert Einstein, São Paulo, SP, Brazil; 2BIOINFO-USP Núcleo de Pesquisa em Bioinformática, São Paulo, SP, Brazil

 

 

Breast

Room 4E                    Thursday 13:30 - 15:30

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                  2867.    Rapid Fat Suppression in MRI of the Breast with Short Binomial Pulses

Glen Morrell1

1University of Utah, Salt Lake City, Utah, USA

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                  2868.    Simultaneous Acquisition of Fat and Water Volume Images of the Breast with
                                    T2-Like Contrast Using Vastly Undersampled Isotropic Projection (VIPR) SSFP

Catherine J. Moran1, Aiming Liu2, Youngkyoo Jung1, Frederick Kelcz1, Ethan Brodsky1, Thomas M. Grist1,

Sean B. Fain1, Walter F. Block1

1University of Wisconsin, Madison, Wisconsin, USA; 2Stanford University, Stanford, California, USA

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                  2869.    Improved DCE-MRI in Bilateral Breast Imaging with Fat Suppressed TRICKS

Neville Dali Gai1, Manojkumar Saranathan2, Sandeep Gupta3, David Thomasson1, Catherine Chow1

1National Institutes of Health, Bethesda, Maryland, USA; 2Indian Institute of Science, Bangalore, Karnataka, India;
3
GE Healthcare, Hanover, Maryland, USA

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                  2870.    The Applicability of K-T GRAPPA for Dynamic Contrast Enhanced MRI

Feng Huang1

1Invivo Corporation, Gainesville, Florida, USA

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                  2871.    High Resolution Bilateral Dynamic Contrast Enhancement Breast Imaging

Jin Hyung Lee1, Charles H. Cunningham1, Brian A. Hargreaves1, Logi Vidarsson1, Dwight G. Nishimura1,

John M. Pauly1, Bruce L. Daniel1

1Stanford University, Stanford, California, USAText Box:  

 

                  2872.    “Direct Imaging” Method for Bilateral Breast Imaging Using Micro-Strip Coils

Jian-xiong Wang1, Elizabeth Ramsay1, Yangmei Li1, Donald B. Plewes1

1Sunnybrook & Women's College Health Science Centre, Toronto, ON, Canada

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                  2873.    Contrast Agent Enhanced Breast Imaging with a Combined 3D Dual Echo Dixon
                                and Parallel Imaging Technique

Jingfei Ma1, Anthony T. Vu2, Jong Bum Son1, 3, Yinan Liu1, 3, Adrian Knowles2, Jason Polzin2, Constance Lehman4

1University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA; 2GE Healthcare Technologies, Waukesha, Wisconsin, USA;
3
Texas A & M University, College Station, Texas, USA; 4Seattle Cancer Care Alliance, Seattle, Washington, USAText Box:  

 

                  2874.    Comparisons of Water-To-Fat Ratios in Malignant, Benign Breast Lesions, and Normal
                                Breast Parenchyma: An In Vivo Proton MRS Study

Sunitha B. Thakur1, Lia Bartella1, Nicole M. Ishill1, Elizabeth A. Morris1, Laura Liberman1, David D. Dershaw1, Hedvig Hricak1,
Jason A. Koutcher1, Wei Huang1

1Memorial Sloan Kettering Cancer Center, New York, New York, USAText Box:  

 

                  2875.    Breast Cancer Diagnosis Using Single-Voxel MRS Measurement of Apparent
                                Diffusion Coefficient of Water

Curtis Andrew Corum1, Adeka D. McIntosh1, Angela L. Styczynski1, Nathaniel J. Powell1, Janice R. Kruse1,

Patrick J. Bolan1, Michael Nelson1, Tim H. Emory1, Douglas Yee1, Todd M. Tuttle1, Lenore I. Everson1,

Michael Garwood1

1University of Minnesota, Minneapolis, Minnesota, USA

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                  2876.    Can MRS Improve Our Ability to Distinguish Between Benign and Malignant Lesions?

Richard Kinh Gian Do1, Linda Moy1, Nouha Salibi2, Cecilia L. Mercado1, Kelly Anne McGorty1, Mary Kitazono3, Elizabeth Hecht1

1New York University, New York, New York, USA; 2Siemens Medical Solutions, St. Louis, Missouri, USA;
3
Keck School of Medicine of USC, Los Angeles, California, USA

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                  2877.    Localized 13C NMR Spectroscopy in the Human Breast In Vivo

Isabelle valentine Iltis1, Patrick J. Bolan1, Hellmut Merkle1, Carl J. Snyder1, Curtis Andrew Corum1, Kamil Ugurbil1,
Michael Garwood1, Pierre-Gilles Henry1

1Center for Magnetic Resonance Research, Minneapolis, Minnesota, USA

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                  2878.    Improved Measurement of Choline-Containing Compounds in Malignant Breast
                                Tumors Using Multiple Long-TEs Averaging MR Spectroscopy

Hyun-Man Baik1, Min-Ying Su1, O. Nalcioglu1

1University of California-Irvine, Irvine, California, USA

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                  2879.    Change of ADC Value of Breast Cancer in Patients Undergoing Neoadjuvant Chemotherapy:
                                Preliminary Study

Guangwei Jin1, Ningyu An1, Youquan Cai1

1PLA General Hospital, Beijing, People’s Republic of China

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                  2880.    Breast Cancer Evaluation Using Diffusion Weighted MR-Imaging –
                                Prior to and Following Chemotherapy   Can DWI Predict Chemotherapeutic Response?

Paul Weatherall1, Qi Peng2, Yao Ding3, Roderick W. McColl3, Debu Tripathy3, Jonathan M. Chia4, Ralph P. Mason3

1University of Texas Southwestern Medical Center, Dallas, Texas, USA; 2University of Texas Health Science Center San Antonio, San Antonio, Texas, USA; 3UT Southwestern Medical Center, Dallas, Texas, USA; 4Philips Medical Systems, Dallas, Texas, USA

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                  2881.    Do Diffusion Changes Occur Prior to Size Changes in Breast Tumours Undergoing
                                Neoadjuvant Chemotherapy?

Martin Darren Pickles1, Peter Gibbs1, Martin Lowry1, Lindsay W. Turnbull1

1University of Hull, Hull, East Yorkshire, UK

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                  2882.    The Role of Apparent Spin-Spin Relaxation in Assessing Response to Treatment in
                                    Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy

Martin Darren Pickles1, Martin Lowry1, Lindsay W. Turnbull1

1University of Hull, Hull, East Yorkshire, UK

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                  2883.    Contrast-Enhanced MRI for Assessing the Response of Invasive Breast Cancer to
                                Neoadjuvant Chemotherapy

Alan Howard Stolpen1, Jeong Mi Park1, Mark W. Karwal1, Megha Garg1

1University of Iowa, Iowa City, Iowa, USA

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                  2884.    Fast Exchange Regime Analysis of the Response to Treatment in Human Breast Cancer

Thomas Yankeelov1, Martin Lepage2, A. Bapsi Chakravarthy1, Kenneth J. Niermann1, Cheryl R. Herman1,

Kevin McManus1, Mark C. Kelley1, Ingrid Mayer1, Ingrid Meszoely1, John C. Gore1

1Vanderbilt University, Nashville, Tennessee, USA; 2Universite de Sherbrooke, Sherbrooke, QC, Canada

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                  2885.    Volumetric Texture Analysis of DCE-MR Images of the Breast Using Gray-Level
                                Co-Occurrence Matrix Method

Weijie Chen1, Maryellen L. Giger1

1The University of Chicago, Chicago, Illinois, USA

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                  2886.    Textural Analysis Optimisation in MRI of the Breast

Tom Beach1, Peter Gibbs1, Martin D. Pickles1, Lindsay Turnbull1

1University of Hull, Hull, UK

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                  2887.    Bootstrap Ensemble Neural Networks in MRI of the Breast

Peter Gibbs1, Muthyala Sreenivas1, Andrew Hunter2, Lindsay Turnbull1

1University of Hull, Hull, UK; 2Lincoln University, Lincoln, UK

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                  2888.    Breast MRI Lesion Classification: Comparison Between Human Readers and
                                Backpropagation Neural Network (BNN)

Lina Arbash Meinel1, Alan Stolpen2, Kevin Berbaum2, Laurie Fajardo2, Joseph M. Reinhardt3

1Philips Research USA, Chicago, Illinois, USA; 2University of Iowa Hospitals, Iowa City, Iowa, USA; 3University of Iowa, Iowa City, Iowa, USA

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                  2889.    Artificial Neuronal Network Analysis of Neoadjuvant Chemotherapy Response Using
                                Quantitative Morphological, Texture and Enhancement Kinetic Parameters

Yong Chu1, Ke Nie1, Hon J. Yu1, Jeon-Hor Chen1, Orhan Nalcioglu1, Min-Ying Su1

1University of California, Irvine, California, USA

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                  2890.    Clinical Evaluation of Combining Dynamic Contrast Enhancement MRI and Diffusion
                                    Weighted MR Imaging for Diagnosis of Breast Lesion

Xiaopeng Zhang1, Jie LI1, Yinshi Sun1, Lei Tang2, Kun Cao3

1Beijing Cancer Hospital,Peking University School of Oncology, Beijing, People’s Republic of China;
2
Beijng Cancer Hospital, Peking University School of Oncology, Beijing, People’s Republic of China;
3
Beijing Cancer Hospital, Peking University School of Oncology, Beijing, People’s Republic of China

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                  2891.    Differentiation of Malignant from Bening Breast Lesions by Diffusion-Weighted
                                Imaging with ASSET Technique

Guangwei Jin1, Ningyu An1, Yu Cai1

1PLA General Hospital, Beijing, People’s Republic of China

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                  2892.    MR-Elastography for Breast Lesion Characterization - The Effect of Rheology on
                                Its Diagnostic Impact

Ralph Sinkus1, Katja Siegmann2, Tanja Xydeas2, Jeremy Bercoff3, Mickael Tanter1, Benjamin Robert1, Mathias Fink1

1Laboratoire Ondes et Acoustique, Paris, France; 2University Tuebingen, Tuebingen, Germany; 3SuperSonic Imagine, Aix-en-Provence, France

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                  2893.    Assessment of Magnetization Transfer and Tissue Blood Flow Imaging in Human
                                Breasts Tissue by GREAST

Ka-Loh Li1, Lisa J. Wilmes1, Jessica Gibbs1, Eric Han2, Greg Zaharchuk1, Christopher P. Hess1, Bonnie Joe1,

Nola Hylton1

1University of California, San Francisco, San Francisco, California, USA;
2
GE Healthcare Global Applied Science Laboratory,, Menlo Park, California, USAText Box:  

 

                  2894.    The Value of T2 Imaging in Establishing Benignancy or Malignancy of Enhancing Lesions
                                Detected by Gd-Enhanced Breast MRI

Frederick Kelcz1, Mai A. Elezaby1

1University of Wisconsin, Madison, Wisconsin, USAText Box:  

 

                  2895.    Parametric Mapping of Contrast Kinetics from Rapid Radial DCE-MR Breast Images

Lawrence Dougherty1, Hee Kwon Song1, Peter J. Moate1, Linda White Nunes2, Mark A. Rosen1, Raymond C. Boston1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Pennsylvania Hospital, Philadelphia, Pennsylvania, USA

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                  2896.    Volumetric Mapping of the Longitudinal to Transverse Relaxation Times Ratio
                                (T1/T2) of the Entire Human Breast

Jaroslaw Nicholas Tkacz1, Yommy Chiu2, Hernan Jara2

1Boston University Medical Center, Boston, Massachusetts, USA;
2
Boston University, Boston, Massachusetts, USA

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                  2897.    Breast MR Electrical Impedance Tomography Toward Breast Cancer Imaging

H. Y. Heo1, Y. Cho1, B. I. Lee1, S. H. Oh1, T.-S. Kim1, S. Y. Lee1, E. J. Woo1

1Kyung Hee University, Yongin, Gyeonggi, Republic of KoreaText Box:  

 

                  2898.    Study of Marker Component for Low Susceptibility Tri-Modalities
                                Breast Tumor Localization

Yangmei Li1, Claire Holloway1, Jian-Xiong Wang1, Donald B. Plewes1

1Sunnybrook and Women's Health Science Centre, University of Toronto, Toronto, Ontario, Canada

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                  2899.    Negative Pressure Fixation Device to Reduce Motion Artifacts on
                                Contrast-Enhanced MR Imaging of the Breast

Asha Balakrishnan1, Daniel F. Kacher2, Steven E. Chavoustie3

1Massachusetts Institute of Technology, Cambridge, Massachusetts, USA;
2
Brigham and Women's Hospital, Boston, Massachusetts, USA; 3University of Miami, Miami, Florida, USA

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                  2900.    7T High Resolution Breast MRI

Ray F. Lee1, Linda Moy1, Ryan Brown2, KellyAnn McGorty1, Cornel Stefanescu1, Yi Wang2, Naomi Peck1

1New York University, New York, USA; 2Conell University, New York, USA

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                  2901.    Coregistration of Contrast Enhanced MRI and Broadband Diffuse
                                Optical Spectroscopy for Characterizing Breast Cancer

Min-Ying Su1, Hon J. Yu1, Natasha S. Shah1, David J-B Hsiang1, Rita S. Mehta1, Albert E. Cerussi1,

Bruce J. Tromberg1, Orhan Nalcioglu1

1University of California, Irvine, California, USA

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                  2902.    Diffusion Tensor Imaging of the Breast: Preliminary Clinical Findings

Savannah C. Partridge1, JoAnn M. Lorenzo1, Sue Peacock1, Bonnie M. Thursten2, John S. McCloskey2,

Wendy B. DeMartini1, Peter R. Eby1, Eric L. Rosen1, Constance D. Lehman1

1University of Washington, Seattle, Washington, USA; 2Seattle Cancer Care Alliance, Seattle, Washington, USA

 

 

 

Perfusion and Permeability in Cancer Models

Room 4E                    Thursday 13:30 - 15:30

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                  2903.    Distribution of Steady State Contrast Agent Concentration and Interstitial
                                Fluid Pressure in Human Xenografts

Yaron Hassid1, Raanan Margalit1, Edna Haran Furman1, Maya Dadiani1, Hadassa Degani1

1Weizmann Institute of Science, Rehovot, Israel

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                  2904.    Parallel Observation of Left Ventricular Arterial Input Function and Brain
                                Perfusion in Rats Using a Multi-Coil System

Stephen Pickup1, Sanjeev Chawla1, Dae-Hong Kim1, Harish Poptani1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA

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                  2905.    Early Effects of Combretastatine A-4-P on Rat Bladder Tumor Heterografts Assessed by
                                Combined Carbogen Based fMRI and T2 Mapping

Carole D. Thomas1, Christine Walczak1, Julia Kaffy2, Renée Pontikis2, Jacqueline Jouanneau2, Andreas Volk1

1Institut Curie, Orsay, France; 2Institut Curie, Paris, France 

 

 

 

                  2906.    Contrast Agent Distribution Function (CADF), a New Dynamic MRI Parameter from Simultaneous
                                Measurement of Relaxation Rates R1 and R2* by a New Saturation-Recovery Multi-Gradient-Echo
                                Snapshot Sequence: Concept and First Application to Colorectal Tumor Xenografts in Mice

 

Melanie Heilmann1, Jean-Luc Dimicoli1, Carole D. Thomas1, Christine Walczak1, Andreas Volk1

1Institut Curie - Research Center, Orsay, FranceText Box:  

 

                  2907.    Direct Comparison of Macromolecular Contrast Agent Vistarem with Dotarem for Detecting Drug
                                Effects on Tumor Vasculature by DCE MRI

Peter R. Allegrini1, Claudia Weidensteiner1, Paul M.J. McSheehy1

1Novartis Inst. for BioMedical Research, Basel, BS, Switzerland

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                  2908.    Longitudinal Studies of Angiogenesis in Hormone Dependent Shionogi Tumours

Trevor Wade1, Piotr Kozlowski2

1University of British Columbia, Vancouver, British Columbia, Canada;
2
Prostate Centre at Vancouver General Hospital, Vancouver, British Columbia, Canada

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                  2909.    DCE-MRI for Evaluation of Response to Gefitinib: Comparison of Two Treatment Regimens
                                in a Breast Cancer Model

Lisa J. Wilmes1, Ka-Loh Li1, Sheye Aliu1, Donghui Wang1, Byron C. Hann1, Mark M. Moasser1, Nola M. Hylton1

1University of California San Francisco, San Francisco, California, USA

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                  2910.    Monitoring Micro-Vasculature Damage Induced by Radiotherapy on Mouse Breast Carcinomas
                                Using DCE-MRI

Martin Pellerin1, Luc Tremblay1, Benoit Paquette1, Martin Lepage1

1Université de Sherbrooke, Sherbrooke, QC, Canada
 

 

                  2911.    DCE MRI Detected Differential Response to ZD6126 of Metastatic Versus Indolent
      Human Melanoma

Rong Zhou1, Hui Qiao1, Lin Z. Li1, Xin Li2, Phyllis Wachsberger3, Charles S. Springer, Jr2, Mary JC Hendrix4,

Jerry D. Glickson1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Oregon Health & Science University, Portland, Oregon, USA;
3
Thomas Jefferson University, Philadelphia, Pennsylvania, USA; 4University of Chicago, Chicago, Illinois, USA

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                  2912.    Short-Term Treatment with the Triple Angiokinase Inhibitor, BIBF 1120, Affects Vascular Permeability
                                and Perfusion of Human Tumor Xenografts in Nude Mice

Martin Krssak1, Monika Kriz1, Frank Hilberg1

1Boehringer Ingelheim Austria, Vienna, Austria

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                  2913.    MRI of Calu-6 Lung Tumors for the Assessment of the Anti-Vascular Activity of MN-029

Nathalie Just1, Veronique Rancier1, Nicolas Guilbaud1, Philippe Genne1, Kenneth Locke2

1Oncodesign Biotechnology, Dijon, France; 2MediciNova Inc, San Diego, California, USA

 

 

Cancer Models: Assessment of Vascular Function

Room 4E                    Thursday 13:30 - 15:30

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                  2914.    Nonlinear Correction of Arterial Input Function Measured with Spoiled Gradient Echo Sequences

Matthias C. Schabel1

1University of Utah, Salt Lake City, Utah, USA

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                  2915.    Modelling DCE-MRI Arterial Input Functions in Rats

Deirdre McGrath1, Tony Lacey2, Daniel Bradley2, Chris Taylor1, Geoff Parker1

1University of Manchester, Manchester, Lancashire, UK; 2Astrazeneca, Alderley Park, Macclesfield, Cheshire, UK

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                  2916.    An Adaptive Bayesian MRF Approach for DCE-MR Imaging

Volker J. Schmid1, Brandon Whitcher2, N. Jane Taylor3, Anwar R. Padahni3, Guang-Zhong Yang1

1Imperial College London, London, England, UK; 2GlaxoSmithKline, Greenford, England, UK; 3Mount Vernon Hospital, Northwood, England, UK

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                  2917.    Tissue Assessment in Gliomas: Comparison of Tumor Blood Volume, Vascular Permeability
                                by Perfusion-Weighted MR Imaging and Tl-201 SPECT

Hidemasa Uematsu1, Tatsuro Tsuchida1, Hirohiko Kimura1, Nobuyuki Kosaka1, Harumi Itoh1

1University of Fukui, Fukui, Japan

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                  2918.    Determination of Maturity and Functionality of Tumor Vasculature by MRI: Correlation Between
                                BOLD MRI and DCE MRI Using P792 in Experimental Fibrosarcoma Tumors

Christine Baudelet1, Greg O. Cron1, Bernard Gallez1

1Catholic University of Louvain, Brussels, Belgium

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                  2919.    The Role of Vessel Maturation and Vessel Functionality in Spontaneous Fluctuations
       of T2*-Weighted GRE Signal Within Tumors

Christine Baudelet1, Greg O. Cron1, Réginald Ansiaux1, Nathalie Crokart1, Julie DeWever1, Olivier Feron1,

Bernard Gallez1

1Catholic University of Louvain, Brussels, Belgium

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                  2920.    DCEMRI Detects Effects of Tumors on Adjacent Normal Tissue That Reflect Tumor Grade

Xiaobing Fan1, Milica Medved1, Jonathan N. River1, Marta Zamora1, Gregory S. Karczmar1

1University of Chicago, Chicago, Illinois, USAText Box:  

 

                  2921.    Susceptibility MRI of Vascular Function and Therapeutic Response in LS174T Colorectal
                                Carcinomas Grown Orthotopically in Murine Liver

Tammy Louise Kalber1, Anderson Joseph Ryan2, John R. Griffiths1, John C. Waterton2, Simon P. Robinson1

1St. George's, University of London, London, UK; 2AstraZeneca, Alderley Park, Macclesfield, UK

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                  2922.    Lineshape and Susceptibility in a Rat Glioma Monitored by Echo Planar Spectroscopic Imaging

Gary V. Martinez1, Maria Luisa Garcia Martin1, 2, Gregory S. Karczmar3, Jeffrey R. Alger4, Nikhil Rajguru1,

Robert J. Gillies1

1University of Arizona, Tucson, Arizona, USA; 2CSIC-UAM, Madrid, Spain; 3University of Chicago, Chicago, Illinois, USA; 4UCLA, Los Angeles, California, USA

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                  2923.    MR Perfusion and 1H Spectroscopic Imaging in the Longitudinal Evaluation of Brain Tumor
      Angiogenesis

Narasimha Shastry Akella1, Steven D. Buchthal1, Louis Burt Nabors1, Jan A. den Hollander1

1University of Alabama at Birmingham, Birmingham, Alabama, USA

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                  2924.    Quantitative Assessment of Tumor Microstructure in Canine Brain Using High Resolution DTI
                                Microimaging

Jian-Ming Zhu1, Ping Wang1, John L. Robertson2, John H. Rossmeisl, Jr. 2, Michael E.C Robbins1, Edward G. Shaw1

1Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA;
2
Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, Virginia, USA

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                  2925.    Hypoxia Increases Endothelial Cell Invasion and Migration

Barjor Gimi1, Noriko Mori1, Zaver M. Bhujwalla1

1The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

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                  2926.    MR Imaging of Bone Marrow-Derived Mesenchymal Stem Cells Incorporation Into Tumor
                                Vasculature in Prostate Cancer Models

Lyubov Ostrovskaya1, Yoshinori Kato1, Piotr Walczak1, Baasil Okollie1, Jeff W. Bulte1, Dmitri Artemov1

1Johns Hopkins University, Baltimore, Maryland, USA

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                  2927.    Monitoring of Cellular Uptake of Gadollinium by Dendritic Cells Useful for Tracking the Cell
                                Trafficking in Tumor Using MRI

Raghvendra S. Sengar1, Patricia Griffin1, Daniel Steed1, Tianbing Yang2, Lorissa Villa2, William Chambers2,

Erik Craig Wiener2

1University of Pittsburgh Cancer Institute, Pittburgh, Pennsylvania, USA;
2
University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA

 

 

DCE-MRI in Cancer: Clinical and Analysis

Room 4E                    Thursday 13:30 - 15:30

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                  2928.    DCE-MRI Perinecrotic Imaging Biomarker Signature and Observed Interpatient Heterogeneity

Dee Wu1, Yi Zheng1, Susan Edwards1, Syed Rahmannan1, William TC Yuh2, Nina Mayr2

1University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA; 2Ohio State University, Columbus, Ohio, USA

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                  2929.    Incorporation of Explicit Arterial Input Function for DCE-MRI Quantification: Use in Human
                                Trial of Sorafenib in Renal Cell Carcinoma

Mark Rosen1, Keith Flaherty1, Dan Heitjan1, Brian Schwartz2, Peter O'Dwyer1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Bayer Pharmaceutical Corp, West Haven, Connecticut, USA

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                  2930.    Pixel-Based Quantitative Analysis of Dynamic Contrast-Enhanced MRI of Lung Tumors

Yu-Jen Chen1, Woei-Chyn Chu1, Wen-Yih Isaac Tseng2

1Institute of Biomedical Engineering, National Yang-Ming University, Taipei, Taiwan;
2
Center for Optoelectronic Biomedicine, National Taiwan University College of Medicine, Taipei, TaiwanText Box:  

 

                  2931.    Dynamic Contrast Enhanced MRI as a Priori Predictor of Response in Head and Neck Squamous
                                Cell Carcinoma: Initial Analysis

Amita Shukla-Dave1, H. Stambuk1, Y. Wang1, S. Karimi1, Y. B. Su1, D. G. Pfister1, N. Lee1, J. A. Koutcher1

1Memorial Sloan-Kettering Cancer Center, New York, USA 


 

                  2932.    Pharmacokinetic Analysis of DCE-MRI in Invasive Breast Carcinomas:
                                Correlation with Tumour Grade

 

Aleksandra Radjenovic1, Barbara J. G. Dall2, Steven Frederick Tanner1, Sarah E. Bacon2, Daina Dambitis2,

John Peter Ridgway2, Michael A. Smith3

1University of Leeds, Leeds, UK; 2Leeds General Infirmary, Leeds, UK; 3University of Teesside, Middlesbrough, UK

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                  2933.    The Extent and Severity of Vascular Leakage as Evidence of Tumor Aggressiveness in
                                High-Grade Gliomas

Yue Cao1, Vijaya Nagesh1, Daniel Hamstra1, Christina I. Tsien1, Ross D. Brian1, Thomas L. Chenevert1, Larry Junck1, Theodore S. Lawrence1

1University of Michigan, Ann Arbor, Michigan, USA

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                  2934.    Radiologist Selection of Tumor Regions of Interest for Dynamic Contrast Enhanced MRI Analysis:
                                Effect on Reproducibility and Spread of Modelled and Non-Modelled Parameters

Adrian Tang1, David Collins2, James d'Arcy1, Martin Leach1, Simon Walker-Samuel1, Toni Wallace2, Nandita deSouza1

1Institute of Cancer Research, Sutton, Surrey, UK; 2Royal Marsden NHS Foundation Trust, Sutton, Surrey, UKText Box:  

 

                  2935.    What is the Optimal Cohort Size for a Reproducibility Study of Dynamic Contrast-Enhanced MRI?

N Jane Taylor1, James A. d'Arcy2, Simon Walker-Samuel2, David J. Collins2, Benjamin Knowles2, J James Stirling1, Toni Wallace2,
Dow-Mu Koh2, Adrian Tang2, Chooi Lee2, Martin O. Leach2, Gordon J S Rustin1, Anwar R. Padhani1

1Mount Vernon Hospital, Northwood, Middlesex HA6 2RN, UK; 2Royal Marsden Hospital, Sutton, Surrey SM2 5PT, UK

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                  2936.    Reproducibility of Pharmacokinetic Parameters Using Different Input Functions in a
                                Multi-Center Non-Expert Phase I Oncology Clinical Trial

Vahan Sharoyan1, David White2, Radhika Sivaramakrishna1, Susan Galbraith3, Ali Guermazi1, Caroline Reinhold1, Anwar Padhani 1, 4

1Synarc, Inc., San Francisco, California, USA; 2Synarc, Inc.,, San Francisco, California, USA;
3
Bristol Myers Squibb Company, Princeton, New Jersey, USA; 4Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK

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                  2937.    Optimal Quantification of DCE-MRI Data Using Reference Tissue Normalisation

Simon Walker-Samuel1, Benjamin R. Knowles1, James A. d'Arcy1, Neil J. Smith2, Gina Brown3, Martin O. Leach1, David J. Collins1

1Institute of Cancer Research, Sutton, Surrey, UK; 2Mayday University Hospital, Thornton Heath, Surrey, UK;
3
Royal Marsden and NHS Foundation Trust, Sutton, Surrey, UK