TRADITIONAL POSTERS

MRI Systems

Hall 14.1                     Monday 14:00 - 16:00

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                  988.      Accelerated Real-Time MRI with Distributed Computing Using Standard Scanner Hardware
 

Ethan K. Brodsky1, Walter F. Block1

1University of Wisconsin - Madison, Madison, Wisconsin, USA

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                  989.      Reducing Data Handling Issues in Large Coil Arrays by ‘If’ Undersampling
 

Naresh Yallapragada1, Steven M. Wright1

1Texas A&M University, College Station, Texas, USA

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                  990.      Ultra High-Order Global Shimming of the Mouse Brain Using Diamagnetic and
                              Paramagnetic Passive Shims

 

Kevin M. Koch1, Peter B. Brown1, Douglas L. Rothman1, Robin A. de Graaf1

1Yale University, New Haven, Connecticut, USA

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                  991.      Development of a Compact MRI Using a Permanent Magnet for Trabecular
                              Bone Microstructure Measurements

 

Sadanori Tomiha1, Shinya Handa1, Katsumi Kose1, Tomoyuki Haishi2

1University of Tsukuba, Tsukuba, Ibaraki, Japan; 2MRTechnology, Inc., Tsukuba, Ibaraki, Japan

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                  992.      Gradient Coil Array for the Super-Parallel MRI: Experimental Evaluation
 

Fumi Okada1, Shinya Handa1, Katsumi Kose1

1University of Tsukuba, Tsukuba, Ibaraki, Japan

 

                  993.      Residual Magnetism in an MR Suite After Field-Rampdown of an 8T Superconducting Magnet

Steffen Sammet1, Regina Maria Koch1, Francisco Aguila1, Michael V. Knopp1

1The Ohio State University, Columbus, Ohio, USA

 

                  994.      An Efficient Multiple Field of View Gradient Coil Set

Qin Liu1, Anthony Mantone2, Graeme C. McKinnon1, Michael B. Sellers3

1GE Healthcare, Waukesha, Wisconsin, USA; 2GE Healthcare, Florence, South Carolina, USA; 3GE Healthcare, Oxford, UK

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                  995.      Investigation of Dynamic Range Requirement for MRI Signal Transmission by Optical Fiber Link
 

Jing Yuan1, Juan Wei1, Chenpeng Du2, Gary X. Shen1

1The University of Hong Kong, Hong Kong, People’s Republic of China; 2MRI Lab, Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong, People’s Republic of China

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                  996.      Designing Active Feedback-Based Contrast Enhancement for In Vivo Imaging
 

Susie Yi Huang1, Dennis W. Hwang2, Lian-Pin Hwang2, 3, Yung-Ya Lin4

1Harvard Medical School, Boston, Massachusetts, USA; 2National Taiwan University, Taipei, Taiwan; 3Academia Sinica, Taipei, Taiwan; 4University of California, Los Angeles, Los Angeles, California, USA

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                  997.      Ultra-Efficient Shielded Dome Gradient Coils
 

Michael Poole1, Richard Bowtell1

1University of Nottingham, Nottingham, Nottinghamshire, UK

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                  998.      Radiation Gel Dosimetry Using an Earth Field NMR Relaxometer
 

Maarten Veevaete1, Oliver Bislich1, Helmut Wiliam Fischer1

1University of Bremen, Bremen, Germany

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                  999.      MRI/PET Insert: Investigations of Eddy Currents on Copper Shields in the Bore
 

Bo Joseph Peng1, Jeff Walton1, Ciprian Catana1, Simon R. Cherry1, Jacob Willig-Onwuachi, 12

1University of California, Davis, California, USA; 2Grinnell College, Grinnell, Iowa, USA

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                  1000.    Homogeneity and Shimming Requirements for a Field-Cycled MRI/PET Scanner
 

Kyle Michael Gilbert1, William Bradfield Handler1, Timothy James Scholl1, Blaine Alexander Chronik1

1The University of Western Ontario, London, Ontario, Canada

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                  1001.    Digital Wireless Transmission for MRI Signals
 

Juan Wei1, Guang Zheng Liu2, Jing Yuan1, Yong Pang1, Gary X. Shen1

1The University of Hong Kong, Hong Kong, People’s Republic of China; 2Tianjin University, Tianjin, People’s Republic of China

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                  1002.    A Wide Band Frequency Transverter for High Field MRI
 

Ralph Oppelt1, Jan Bollenbeck1, Philipp Höcht1, Wilfried Schnell1

1Siemens AG, Erlangen, Germany

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                  1003.    MRI and the Cell Processor
 

Joseph Czechowski1, Stephen Zingelewicz1, Branden Moore1, Luca Marinelli1, Christopher Hardy1, Mohamed El-Demerdash2

1General Electric Company, Niskayuna, New York, USA; 2General Electric Company, Waukesha, Wisconsin, USA

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                  1004.    First Order Dynamic Shimming for  7 Tesla  Human Imaging

 

Saikat Sengupta1, Malcolm J. Avison1, David Foxall2, John Gore1

1Vanderbilt University, Nashville, Tennessee, USA; 2Philips Medical Systems, Cleveland, Ohio, USA

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                  1005.    An Independent Spectrometer and Coil Insert for Research on Clinical MR Systems

 

Martyn NJ Paley1, Eugeny Krjukov1, James M. Wild1, Paul D. Griffiths1, Michael Lamperth2, Ian R. Young2

1University of Sheffield, Sheffield, Yorkshire, UK; 2Imperial College, London, UK

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                  1006.    Integrated Low Noise Amplifier and Balun for MRI Receiver-On-Coils

 

Michael A. de Rooij1, William E. Burdick1

1GE Global Research, Niskayuna, New York, USA

 

 

MRI Systems & Gradients

Hall 14.1                     Monday 14:00 - 16:00

 

                  1007.    Fully Integrated Whole Body 3T MRI System for Parallel RF Transmission

Ingmar Graesslin1, Peter Vernickel1, Joachim Schmidt1, Christian Findelklee1, Peter Roeschmann1, Ulrich Katscher1, Christoph Leussler1, Paul Haaker1, Kai-Michael Luedeke1, Jochen Keupp1, Peter Börnert1, Henk Dingemans2, Giel Mens2, Krelis Blom2, Jan vd. Heijden2, Paul Harvey2, Johan Overweg1

                                  1Philips Research Europe, Hamburg, Germany; 2Philips Medical Systems, Best, Netherlands

                   1008.    Efficient RF Coil Simulations with Curvilinear Quadrilateral-Element Method of Moments

                                  Shumin Wang1, Patrick J. Ledden2, Jeff H. Duyn1

1LFMI/NINDS/NIH, Bethesda, Maryland, USA; 2Nova Medical, Inc, Wilmington, Massachusetts, USA

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                  1009.    Modeling Loaded RF Coils Using the Method of Moments

 

Aghogho Obi1, Rostislav Lemdiasov2, Reinhold Ludwig1, Gene Bogdanov1

1Worcester Polytechnic Institute, Worcester, Massachusetts, USA; 2Insight Neuroimaging LLC, Worcester, Massachusetts, USA

 

                  1010.    Boundary Element Method for Calculation of Induced Electric Fields Due to Switched
                             Magnetic Field Gradients and Movement in Strong Static Fields

 

Clemente Cobos Sanchez1, Paul M. Glover1, Henry Power1, Liviu Marin1, Adib Becker1, Arthur Jones1, Richard W. Bowtell1

1University of Nottingham, Nottingham, UK

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                  1011.    Effect of Head Size to B1, SNR and SAR

 

Jinfeng Tian1, Carl J. Snyder1, Lance Delabarre1, can Akgun1, Wanzhan Liu1, Christopher M. Collins2, Anand Gopinath1, Thomas Vaughan1

1University of Minnesota, Minneapolis, Minnesota, USA; 2Pennsylvania State University, Pennsylvania, USA

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                  1012.    The Effect of Shield Proximity on the Mode Distribution of a Birdcage Resonator

 

Shahed Reza1, Sathya Vijayakumar1, Randy Duensing1, Feng Huang1, Mark Limkeman1, Charles Saylor1

1Invivo Diagnostic Imaging, Gainesville, Florida, USA

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                  1013.    A Whole-Body 7 Tesla RF Excitation Scheme with Much Improved B1+ Field Homogeneity
                              and Local/Global SARs Over Quadrature Excitation

 

Tamer Selim Ibrahim1, 2, Lin Tang2

1University of Pittsburgh, Pittsburgh, Pennsylvania, USA; 2University of Oklahoma, Norman, Oklahoma, USA

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                  1014.    FDTD Simulations of RF Inhomogeneities in Ultrahigh-Field MRI Systems of Up to 11.7 T

 

Masaki Sekino1, Shoogo Ueno2, Hiroyuki Ohsaki1

1The University of Tokyo, Kashiwa, Chiba, Japan; 2Kyushu University, Fukuoka, Japan

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                  1015.    Tapered Head Gradient Coil Design Using the Wave Equation Method

 

Viktor Vegh1, Huawei Zhao1, Graham J. Galloway1, Ian M. Brereton1

1University of Queensland, Brisbane, Queensland, Australia

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                  1016.    Improved Fourier Based Method for Calculating Field Inhomogeniety from Known
                             Susceptibility Distribution

 

Jaladhar Neelavalli1, Yu Chung Norman Cheng2, Ewart Mark Haacke2

1Wayne State University, Detroit, Michigan, USA; 2Wayne State University, Michigan, USA

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                  1017.    Simulations of a 3D-Segmented Asymmetric Body Coil for Parallel Transmission

 

Ingmar Graesslin1, Sven Biederer1, Konstantinos Falaggis1, Dennis Glaesel1, Peter Vernickel1, Ulrich Katscher1, Peter Börnert1

1Philips Research Europe, Hamburg, Germany

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                  1018.    A 14.1 Tesla Animal Coil Design for Homogenous and Focused RF Excitation

 

Tamer Selim Ibrahim1, 2, Vanishree Ranganath2

1University of Pittsburgh, Pittsburgh, Pennsylvania, USA; 2University of Oklahoma, Norman, Oklahoma, USA

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                  1019.    A Proposed Ultra High Field RF Coil Design for Axial Human Brain Imaging

 

Tamer Selim Ibrahim1, 2, Roney Abraham2

1University of Pittsburgh, Pittsburgh, Pennsylvania, USA; 2University of Oklahoma, Norman, Oklahoma, USA

 

                  1020.    Decoupling of a Multi Channel Transmit/Receive Coil Array Via Impedance Inversion
 

Christian Findeklee1, Jens Eichmann2, Peter Vernickel1

1Philips Research Europe, Hamburg, Germany; 2Hamburg University of Technology TUHH, Hamburg, Germany
 

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                  1021.    Field Propagation Phenomena in Ultra High Field NMR: A Maxwell-Bloch Formulation

 

Andrew JM Kiruluta1

1Harvard University, Cambridge, Massachusetts, USA

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                  1022.    RF Shimming Considering Both Excitation Homogeneity and SAR

 

Zhangwei Wang1, Suk-hoon Oh1, Michael B. Smith1, Christopher M. Collins1

1The Pennsylvania State University, Hershey, Pennsylvania, USA

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                  1023.    Simulation of the Effect of Mode Coupling on SAR for a Birdcage Resonator

 

Shahed Reza1, Randy Duensing1, Sathya Vijayakumar1, Feng Huang1, Mark Limkeman1, Charles Saylor1

1Invivo Diagnostic Imaging, Gainesville, Florida, USA

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                  1024.    Composite Shim Coil Design for System-Specific Field Corrections

 

Parisa Jamali1, Blaine A. Chronik1

1University of Western Ontario, London, Ontario, Canada

 

 

RF Coil:  Non-Arrays

Hall 14.1                     Monday 14:00 - 16:00

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                  1025.    A Rigid Analysis and Experiments for the Complementary Modes in the Multi-Port Reception
                              of a Volume Strip Array

 

Ray F. Lee1, Rong Xue1

1New York University Medical Center, New York, USA

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                  1026.    4 Channel Mouse Array at 7 Tesla

 

Marcos Alonso Lopez1, Felix Breuer2, Nicole Seiberlich1, Daniel Gareis1, Sabine Voll1, Peter Michael Jakob1, 2

1University of Würzburg, Würzburg, Bavaria, Germany; 2Research Center Magnetic Resonance Bavaria (MRB), Würzburg, Bavaria, Germany

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                  1027.    Parallel Transmission with an 8 Channel Whole Body System at 3 T

 

Juergen Nistler1, Ulrich Fontius1, Lawrence L. Wald2, Elfar Adalsteinsson3, Kawin Setsompop3, Vijay Anand Alagappan2, Franz Hebrank4, Franz Schmitt1, Wolfgang Renz1

1Siemens Medical Solutions, Erlangen, Germany; 2MGH Martinos Center, Charlestown, Massachusetts, USA; 3MIT, Cambridge, Massachusetts, USA; 4Siemens Medical Solutions, Charlestown, Massachusetts, USA

 

                  1028.    A Degenerate Birdcage Coil for Parallel Excitation
 

Vijayanand Alagappan1, Juergen Nistler2, Elfar Adalsteinsson3, Kawin Setsompop3, Ulrich Fontius2, Adam Zelinski3, Markus Vester2, Graham Wiggins4, Franz Hebrank5, Wolfgang Renz2, Franz Schmitt2, Lawrence Wald4

1Athinoula A. Martinos Center for Biomedical Imaging, MGH, Charlestown, Massachusetts, USA; 2Siemens Medical Solutions, Erlangen, Germany; 3Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; 4Athinoula A. Martinos Center for Biomedical Imaging, MGH, charlestown, Massachusetts, USA; 5Siemens Medical Solutions, Charlestown, Massachusetts, USA

 

                  1029.    Towards a Complete Coil Array
 

Zhiyue J. Wang1, 2

1Texas Children's Hospital, Houston, Texas, USA; 2Baylor College of Medicine, Houston, Texas, USA

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                  1030.   
B1+ Region of Interest Localization Through Convex Optimization

 

Christopher Carl Olson1, Lance DelaBarre1, John Thomas Vaughan1, Anand Gopinath1

1University of Minnesota, Minneapolis, Minnesota, USA

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                  1031.    A Novel RF Head Coil for 7T Homogeneity and Parallel Imaging Applications

 

Can Eyup Akgun1, Carl J. Snyder1, Lance DelaBarre1, Jinfeng Tian1, Pierre-Francois Van de Moortele1, Steen Moeller1, Kamil Ugurbil1, John Thomas Vaughan1

1University of Minnesota, Minneapolis, Minnesota, USA

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                  1032.    Comparison of Array Decoupling Mechanisms on Rat Arrays at 1.5 T

 

Tobias Wichmann1, 2, Titus Lanz1, Peter M. Jakob3

1Rapid Biomedical GmbH, Rimpar, Germany; 2Magnetic Resonance Bavaria, Würzburg, Germany; 3University of Würzburg, Würzburg, Germany

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                  1033.    Comparison Between Broadband Decoupling Methods for Microstirp Array

 

Bing Wu1, 2, Yong Pang2, Juan Wei2, Peng Qu2, Chunsheng Wang2, Jing Yuan2, Gary X. Shen2

1GE Healthcare, Beijing, People’s Republic of China; 2The University of Hong Kong, Hong Kong, Hong Kong

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                  1034.    An Inverse Method for Designing RF Phased Arrays with Optimal Coil Geometry

 

Peter Thomas While1, Larry K. Forbes1, Stuart Crozier2

1University of Tasmania, Hobart, Tasmania, Australia; 2University of Queensland, Brisbane, Queensland, Australia

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                  1035.    The Novel 12 Channel Octahedral Transmit/receive Array for Parallel Imaging of Human Head at 3 T.

 

Evgeniya Kirilina1, Thomas Riemer2, Wolfgang Driesel3, Harald E. Moeller3, Frank Seifert1

1Physikalisch-Technischen Bundesanstalt, Berlin, Germany; 2IZKF, Leipzig, Germany; 3Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

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                  1036.    A 4-Channel Optical Link Transmission for RF Coil Array at 1.5T

 

Jing Yuan1, Juan Wei1, Guang Cao2, Yong Pang3, Chenpeng Du3, Gary X. Shen1

1The University of Hong Kong, Hong Kong, People’s Republic of China; 2GE Medical System Asia, Hong Kong, People’s Republic of China; 3MRI Lab, Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong, People’s Republic of China

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                  1037.    Low Noise Preamplifier with Integrated Cable Trap

 

Martin L. Hergt1, Ralph Oppelt2, Markus D. Vester1, Arne Reykowski3, Klaus M. Huber2, Karsten Jahns1, Hubertus J. Fischer1

1Siemens Medical Solutions, Erlangen, Germany; 2Siemens Cooperate Technology, Erlangen, Germany; 3Invivo Corporation, Gainesville, Florida, USA

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                  1038.    A 3D Parallel Imaging Capable Transmit and 16-Channel Receive Array Knee Coil at 3T

 

Xiaoyu Yang1, 2, Tsinghua Zheng1, 2, Hiroyuki Fujita1, 2

1Case Western Reserve University, Cleveland, Ohio, USA; 2University Hospitals of Cleveland, Cleveland, Ohio, USA

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                  1039.    Evaluation of a Degenerated Birdcage Coil for Parallel Imaging

 

Chunsheng Wang1, Peng Qu1, Jing Yuan1, Gary X. Shen1

1The University of Hong Kong, Hong Kong, Hong Kong

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                  1040.    3D-Orthogonal Phased Array Coil for High-Resolution and Low-Distortion EPI Imaging
                              of Monkey Brain at 3.0T

 

Zhigang You1, Wingchi Edmund Kwok1, Mithun Mukherjee1, Marc Mancarella1

1University of Rochester, Rochester, New York, USA

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                  1041.    Comparison of FP, VCSEL and DFB Laser Diode in Optical Transmission for MR RF Coil Array

 

Chenpeng Du1, Jing Yuan1, Gary Xiong Shen1

1The University of Hong Kong, Hong Kong, People’s Republic of China

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                  1042.    A Continuous Capacitance Loop Detector for High Sensitivity 7T MRI

 

Lucas Carvajal1, Kostas Karpodinis1, Duan Xu1, Daniel B. Vigneron1

1University of California San Francisco, San Francisco, California, USA

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                  1043.    SNR and G-Factor Optimized 16-Channel Anterior Cardiac Array for 3T

 

Mike J. Smith1, 2, Scott B. King1, 2

1National Research Council of Canada, Winnipeg, Manitoba, Canada; 2University of Manitoba, Winnipeg, Manitoba, Canada

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                  1044.    Comparison of Transceive Phased Array with TEM Volume Coil for Human Brain Imaging at 4 T.

 

Nikolai I. Avdievich1, Alexey S. Peshkovsky2, Hoby P. Hetherington1

1Albert Einstein College of Medicine, Bronx, New York, USA; 2RF Sensors, LLC, New York, New York, USA

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                  1045.    B1+ Homogeneity and SAR Reduction for Localized Excitation at 7T

 

Bob van den Bergen1, Cornelis A T van den Berg1, L W. Bartels1, Jan J. W. Lagendijk1

1University Medical Center Utrecht, Utrecht, Netherlands

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                  1046.    The Efficiency of 3T Body Transmit Array Coils

 

Eddy B. Boskamp1, Scott A. Lindsay1, John E. Lorbiecki1, Graeme C. McKinnon1

1GE Healthcare, Waukesha, Wisconsin, USA

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                  1047.    Experimental Phased-Array Excitation Guided Utilizing a Computational Electromagnetic
                              Model: Initial Findings

 

Tamer Selim Ibrahim1, YiK-Kiong Hue1, Fernando Boada1, Juergen Nistler2, Joerg Ulrich Fontius2, Franz Schmitt2

1University of Pittsburgh, Pittsburgh, Pennsylvania, USA; 2Siemens Medical Systems,

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                  1048.    Array SNR and Coupling Versus the Input Impedance of the Preamplifiers

 

Eddy B. Boskamp1, Ke Feng2, Bijay K. Shah2, Steven M. Wright2

1GE Healthcare, Waukesha, Wisconsin, USA; 2Texas A&M University, College Station, Texas, USA

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                  1049.    Optimized Quadrature Surface Coils Incorporating Circular, Figure-8 Loops, and Strips

 

Ananda Kumar1, Paul Arthur Bottomley1

1Johns Hopkins University, Baltimore, Maryland, USA

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                  1050.    Simple Digital Tuning System for Large Arrays of Coils

 

Ke Feng1, Mary Preston McDougall1, Steven M. Wright1

1Texas A&M University, College Station, Texas, USA

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                  1051.    Stretchable Coil Arrays

 

Jurek Antonin Massner1, Nicola De Zanche1, Klaas P. Pruessmann1

1University and ETH Zurich, Zurich, Switzerland

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                  1052.    Wavelet-Based Mode-Scanning Excitation (MSE) for Selective Excitation at High Field

 

Ray F. Lee1, Ting Song2, Rong Xue1, Andrew F. Laine2

1New York University Medical Center, New York, USA; 2Columbia University, New York, USA

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                  1053.    An Open 16-Channel Transmission Line Array for 7T

 

Joshua J. Holwell1, 2, Simon A. Lovell1, Kenneth M. Bradshaw1, Eddie J. Auerbach2, Gregor Adriany2, J Thomas Vaughan2

1MR Instruments Inc., Minneapolis, Minnesota, USA; 2University of Minnesota, Minneapolis, Minnesota, USA

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                  1054.    B1 Transmit Field Manipulation at 7 Tesla Using Controlled Decoupling of Array Coil Elements (CODACE)

 

Graham Charles Wiggins1, Elizabeth Zakszewski2, Christopher John Wiggins1, Lawrence L. Wald1

1Massachusetts General Hospital, Charlestown, Massachusetts, USA; 2MIT, Cambridge, Massachusetts, USA

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                  1055.    20 Channel Coil Array for High Resolution Imaging of the Optic Nerve

 

J. Rock Hadley1, Emilee Minalga1, Dennis L. Parker1

1University of Utah, Salt Lake City, Utah, USA

 

 

RF Coil Technology:  Non-Array

Hall 14.1                     Monday 14:00 - 16:00

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                  1056.    Magnetic Resonance Microimaging of Adult Zebrafish Brain Using Cryoprobe Technology

 

A. Alia1, S Kabli1, D. Gross2, D. Marek3, T. Oerther2, M. Sacher4, H. P. Spaink5, H. J.M. de Groot1

1Leiden University, Leiden, Netherlands; 2Bruker BioSpin GmbH, Karlsruhe, Germany; 3Bruker BioSpin AG, Fallanden, Switzerland; 4Bruker BioSpin AG, Fallanden, Switzerland; 5Institute of Biology, Leiden, Netherlands

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                  1057.    A Circularly Polarized Birdcage Coil with a Single Port

 

Yoshihisa Soutome1, Hideta Habara1, Hisaaki Ochi1

1Hitachi Ltd., Kokubunji, Tokyo, Japan

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                  1058.    A Histological Slice Imaging Coil for 7.0 T MRI

 

Bu Sik Park1, Mark D. Meadowcroft1, Christopher Michael Collins1, Michael B. Smith1, Qing X. Yang1

1The Pennsylvania  State University, Hershey, Pennsylvania, USA

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                  1059.    MR-Guided Near-Infrared Spectroscopy System for Rodent Tumor Tomography

 

Brian W. Pogue1, Scott C. Davis1, Jia Wang1, Subhadra Srinivasan1, Summer L. Gibbs1, Shudong Jiang1, Keith D. Paulsen1, Peter Mazurkewitz2, Daniel Wirtz2, Christoph Leussler2

1Dartmouth College, Hanover, New Hampshire, USA; 2Philips Research Europe, Hamburg, Germany

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                  1060.    Multi Tuned Coupled Microstrip Resonator for High Field Magnetic Resonance Imaging
                              at 9.4T Human System

 

Sasidhar Tadanki1, Gene Bagadanov1, Reinhold Ludwig1, Mathew E. Brevard2, Keith R. Thulborn3, Ian Atkinson3

1Worcester Polytechnic Institute, Worcester, Massachusetts, USA; 2Insight Neuroimaging Systems,LLC, Worcester, Massachusetts, USA; 3University of Illinois at Chicago, Chicago, Illinois, USA

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                  1061.    Comparison of Sensitivity and SNR Between 25mm, 50mm and 75mm Diameter Round Coils
                              for Head Imaging on 7T

 

Akira Nabetani1, 2, Hiroyuki Kabasawa1, 2, Hitoshi Matsuzawa2, Tsutomu Nakada2

1GE Yokogawa Medical Systems, Ltd., Hino-shi, Tokyo, Japan; 2University of Niigata, Niigata, Japan

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                  1062.    SAR and B1 Field in a Human Head Model for Birdcage, TEM and Microstrip Coils at 7T

 

Chunsheng Wang1, Yong Pang1, Bing Wu1, Gary X. Shen1

1The University of Hong Kong, Hong Kong, Hong Kong

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                  1063.    Homogeneity Improvement Using a 2 Port Birdcage Coil

 

Juergen Nistler1, Dirk Diehl2, Wolfgang Renz1, Ludwig Eberler1

1Siemens Medical Solution, Erlangen, Germany; 2Siemens Corporate Technology, Erlangen, Germany

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                  1064.    Selective Passive Shielding

 

Chris P. Bidinosti1, Michael E. Hayden1

1Simon Fraser University, Burnaby, BC, Canada

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                  1065.    Quadrature Strip-Line Surface Coil for Ultra-High Field Imaging (7T)

 

Alexa Jones1, Arthur William Magill1, Paul Glover1

1University of Nottingham, Nottingham, UK

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                  1066.    A New Dedicated Coil Setup for In Vivo Measurement of Intramyocellular Lipids by 1H-MRS

 

Michael Neumaier1, Heiko G. Niessen1, Thomas Kaulisch1, Detlef Stiller1

1Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany

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                  1067.    Ultra-Sensitive Micron-Cantilever Detection for MRI

 

Modhurin Banerjee1, Charles Paulson1, Krishna Kurpad1, Daniel M. Ruf1, Daniel van der Weide1, Thomas M. Grist1

1University of Wisconsin,Madison, Madison, Wisconsin, USA

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                  1068.    HTS Surface Coil for MRI of the Patella

 

Jarek Wosik1, Maged R. Kamel1, Lei-Ming Xie1, Lian Xue1, Krzysztof Nesteruk2, Alexander C. Wright3, Felix W. Wehrli3

1University of Houston, Houston, Texas, USA; 2Institute of Physics of Polish Academy of Sciences, Warsaw, Poland; 3University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

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                  1069.    Less Wiggle Room at High-Field: A Segmented Birdcage-Like Example with Excellent Planar Uniformity

 

Xin Chen1, Timothy P. Eagan1, Tanvir N. Baig1, Robert W. Brown1

1Case Western Reserve University, Cleveland, Ohio, USA

 

 

Devices & Implant MRI Safety

Hall 14.1                     Monday 14:00 - 16:00

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                  1070.    Comparison of Measured and Estimated Induced Voltage on Implanted Cardiac Leads Due to
                              MRI Gradient Magnetic Fields

 

Jonathan Edmonson1, Ben Herberg1, Dave Manahan1, Ashish Singal1

1Medtronic Inc., Minneapolis, Minnesota, USA

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                  1071.    Performance of the ASTM-Phantom at 3T

 

Salome Ryf1, Hans Engels2, Peter Boesiger1, Roger Luechinger1

1Institute for Biomedical Engineering, Zurich, Switzerland; 2Philips Medical Systems, Best, Netherlands

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                  1072.    SAR and Temperature Rise Within Tissues Near a Medical Implant

 

Dagang Wu1, Ji Chen1, Shumin Wang2

1University of Houston, Houston, Texas, USA; 2NIH, Bethesda, Maryland, USA

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                  1073.    Safety of Localising Intracranial EEG Electrodes Using MRI

 

David William Carmichael1, John S. Thornton2, Philip J. Allen3, Louis Lemieux1

1UCL Institute of Neurology, London, UK; 2National Hospital for Neurology and Neurosurgery, London, UK; 3National Hospital for Neurology and Neurosurgery, London, UK

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                  1074.    Calorimetric Calibration of SAR Estimates Displayed on GE MR Scanners

 

Krzysztof R. Gorny1, Matt A. Bernstein1, Joel P. Felmlee1, Diana M. Lanners1

1Mayo Clinic College of Medicine, Rochester, Minnesota, USA

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                  1075.    MR-Safety and Compatibility of Intrauterine Devices at 3T and 7T

 

Steffen Sammet1, Regina Maria Koch1, Douglas Arthur Murrey1, Michael V. Knopp1

1The Ohio State University, Columbus, Ohio, USA

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                  1076.    RF Heating Model of Active Implants During MRI Examinations

 

Halise Irak1, Ergin Atalar1, 2

1Bilkent University, Ankara, Turkey; 2Johns Hopkins University, Baltimore, Maryland, USA

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                  1077.    Energy Coupling Between RF Electric Fields and Conductive Wires: Image Artifacts and Heating

 

Todd K. Stevens1, 2, John R. Ives1, Robert Bartha, 12

1University of Western Ontario, London, Ontario, Canada; 2Robarts Research Institute, London, Ontario, Canada

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                  1078.    Avoiding Resonant Lengths of Wire with RF Chokes at 4 Tesla

 

Todd K. Stevens1, 2, John R. Ives1, Robert Bartha, 12

1University of Western Ontario, London, Ontario, Canada; 2Robarts Research Institute, London, Ontario, Canada

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                  1079.    Asymmetric Pacemaker Lead Tip Heating Along the X-Axis in 1.5T and 3T Systems

 

Deborah Anne Langman1, Vibhas S. Desphande2, Feiweier Thorsten3, Gerhard A. Laub2, Paul J. Finn1

1UCLA, Los Angeles, California, USA; 2Siemens, Los Angeles, California, USA; 3Siemens, Erlangen, Germany

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                  1080.    RF Safety Aspects for Hip Implants During MRI: A Comparison Between Numerical
                             Calculations and Experimental Measurements

 

Dan Li1, Jens Stenschke1, Maike Thomann2, Xixi Zhang1, Gregor Schaefers3, Waldemar Zylka4

1University of Applied Sciences Gelsenkirchen; 2University of Applied Sciences Gelsenkirchen, NRW, Germany; 3mr:comp GmbH, Gelsenkirchen, Germany; 4University of Applied Sciences Gelsenkirchen, Gelsenkirchen, NRW, Germany

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                  1081.    Safety and Feasibility of Using Implanted Depth Electrodes for Intracranial EEG-fMRI at 3 Tesla

 

Shannon Boucousis1, Cameron John Bruce Cunningham2, Bradley Goodyear2, Paolo Federico2

1University of Calgary, Calgary, Alberta, Canada; 2University of Calgary, Calgary, Canada

 

 

MR Safety, Bioeffects and Acoustic Noise

Hall 14.1                     Monday 14:00 - 16:00

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                  1082.    Measurement of Visual Evoked Potential During and Following Exposure to Switched Magnetic Fields

 

Sally Eldeghaidy1, T Mistry1, Paul Glover1, Penny A. Gowland1

1University of Nottingham, Nottingham, UK

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                  1083.    Initial Measurements with an Ambulatory Static and Gradient Magnetic Field Dosimeter for
                              Workers in MR Environments

 

Miguel Angel Fuentes1, Stephen Wilson1, Stuart Crozier1

1University of Queensland, St Lucia, Queensland, Australia

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                  1084.    MRI-Based Attenuation Correction for PET Reconstruction

 

Jeffrey Steinberg1, Jun Zhang1, Guang Jia1, Zarine Shah1, Steffen Sammet1, Deborah Hurley1, Nathan Hall1, Michael V. Knopp1

1The Ohio State University, Columbus, Ohio, USA

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                  1085.    RF Shimming and SAR Considerations with an Eight-Element 3T Body Coil

 

Graeme McKinnon1

1GE Healthcare, Waukesha, Wisconsin, USA

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                  1086.    Real-Time SAR Monitoring to Ensure Patient Safety for Parallel Transmission Systems

 

Ingmar Graesslin1, Sven Biederer1, Konstantinos Falaggis1, Peter Vernickel1, Henk Dingemans2, Giel Mens2, Peter Roeschmann1, Christoph Leussler1, Zhiyong Zhai3, Michael Morich3, Ulrich Katscher1

1Philips Research Europe, Hamburg, Germany; 2Philips Medical Systems, Best, Netherlands; 3Philips Medical Systems, Cleveland, Ohio, USA

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                  1087.    RF Safety at 9.4T - Porcine In Vivo Results

 

Devashish Shrivastava1, Bob Schlentz1, Jeramy Kulesa1, Carl Snyder1, Lance DelaBarre1, Tim Hanson1, Paul Iaizzo1, J. Thomas Vaughan1

1University of Minnesota, Minneapolis, Minnesota, USA

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                  1088.    General Method for Acoustic Noise Reduction by Avoiding Resonance Peaks

 

Jouke Smink1, Geert-Jan Plattel1, Paul R. Harvey1, Patrick Limpens1

1Philips Medical Systems, Best, Netherlands

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                  1089.    Modelling Regulatory Compliance of Occupationally Exposed MRI Workers During Gradient Pulsing

 

Stuart Crozier1, Hua Wang1, Adnan Trakic1, Feng Liu1

1The University of Queensland, Brisbane, Queensland, Australia

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                  1090.    SAR Simulations and Experiments for Parallel Transmission

 

Ingmar Graesslin1, Konstantinos Falaggis1, Sven Biederer1, Dennis Glaesel1, Peter Vernickel1, Peter Roeschmann1, Christoph Leussler1, Axel Thran1, Zhiyong Zhai2, Michael Morich2, Ulrich Katscher1

1Philips Research Europe, Hamburg, Germany; 2Philips Medical Systems, Cleveland, Ohio, USA

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                  1091.    RF-Induced Electromagnetic Fields and Implant Heating in MRI

 

Peter Nordbeck1, Florian Fidler1, Ingo Weiss2, Marcus Warmuth1, Michael T. Friedrich2, Philipp Ehses1, Wolfgang Geistert2, Peter M. Jakob1, Mark E. Ladd3, Harald H. Quick3, Wolfgang R. Bauer1

1University of Würzburg, Würzburg, Germany; 2Biotronik GmbH & Co. KG, Berlin, Germany; 3University of Duisburg-Essen, Essen, Germany

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                  1092.    A Conservative Method for Ensuring Safety Within Transmit Arrays

 

Christopher Michael Collins1, Zhangwei Wang1, Michael Bruce Smith1

1The Pennsylvania State University, Hershey, Pennsylvania, USA

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                  1093.    Heating of Metallic Implants and Instruments Induced by Gradient Switching

 

Hansjörg Graf1, Günter Steidle1, Fritz Schick1

1University Hospital of Tübingen, Tübingen, Germany

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                  1094.    The SAR Measurement Phase Transition Method

 

Rocco Romano1, Fausto Acernese2, Pietro Luigi Indovina3, Fabrizio Barone1

1Università degli Studi di Salerno, Fisciano, Italy; 2Istituto Nazionale di Fisica Nucleare, Napoli, Italy; 3Università degli Studi di Napoli "Federico II", Napoli, Italy

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                  1095.    Contactless Measurements of Liquid Sample Electrical Conductivity for Estimating Specific
                              Absorption Rate in MR Applications

 

Valentina Hartwig1, 2, Giulio Giovannetti2, Nicola Vanello, 12, Luigi Landini2, Antonio Benassi2

1University of Pisa, Pisa, Italy, Italy; 2CNR, Pisa, Italy, Italy

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                  1096.    Four Weeks of Close Proximity to the 4.7T Magnet Does Not Stimulate Heat Shock Protein
                              Expression in the Rat Brain

 

Michal Fiedorowicz1, Kinga Stanczak1, Pawel Grieb1, Urszula Tyrankiewicz2, Tomasz Skorka2, Andrzej Jasinski2, 3

1Medical Research Centre PAN, Warszawa, Poland; 2H. Niewodniczanski Institute of Nuclear Physics PAN, Krakow, Poland; 3Cracow Pedagogical University, Krakow, Poland

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                  1097.    FDTD Simulations of Implantable Devices at 3 and 7 Tesla

 

Tamer Selim Ibrahim1, 2, Alayar Kangarlu3, Roney Abraham2

1University of Pittsburgh, Pittsburgh, Pennsylvania, USA; 2University of Oklahoma, Norman, Oklahoma, USA; 3Columbia University, New York, USA

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                  1098.    Numerical Study of Currents in Occupational Workers Induced by Body-Motion Around High-Ultrahigh
                              Field MRI Magnets

 

Stuart Crozier1, Adnan Trakic1, Hua Wang1, Feng Liu1

1The University of Queensland, Brisbane, Queensland, Australia

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                  1099.    Effect of Considering Physiological Response in Temperature Calculations for MRI of the Human Head

 

Zhangwei Wang1, James C. Lin2, Michael B. Smith1, Christopher M. Collins1

1The Pennsylvania State University, Hershey, Pennsylvania, USA; 2University of Illinois at Chicago, Chicago, Illinois, USA

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                  1100.    Effects of Static Magnetic Field Strength on Heart Rate

 

Adam W. Anderson1, Robin Avison1, John C. Gore1

1Vanderbilt University, Nashville, Tennessee, USA

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                  1101.    Acoustic Noise Suppression: Gradient Self-Help?

 

Timothy Patrick Eagan1, Tanvir Baig1, Jamal J. Derakhshan1, Jeffrey L. Duerk1, 2, Robert Brown1

1Case Western Reserve University, Cleveland, Ohio, USA; 2University Hospitals of Cleveland, Cleveland, Ohio, USA

 

 

Safety Regulations and Site Safety Procedure Concerns

Hall 14.1                     Monday 14:00 - 16:00

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                  1102.    Algorithms for Automatic Calculation of Quality Control Metrics for ACR Accrediatation Compliance

 

Zhonghao Bao1, Scott O. Stiving1, Joel P. Felmlee1, Kiaran Patrick McGee1

1Mayo Clinic, Rochester, Minnesota, USA

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                  1103.    Quality Control for 1HMRS Longitudinal Studies

 

Roberto Tarducci1, Otello Presciutti2, Gianni Gobbi2

1Azienda Ospedaliera di Perugia, Perugia, Italy; 2SC di Fisica Sanitaria, Azienda Ospedaliera di Perugia, Perugia, Italy

 

 

MR-Guided Interventions III (devices, sequences, applications)

Hall 14.1                     Monday 14:00 - 16:00

 

                1104.    Negative and Positive Contrast Strategies to Track Cell Encapsulation Devices Post Implantation

Barjor Gimi1, 2, Dmitri Artemov2, Timothy Leong3, David Gracias3, Zaver M. Bhujwalla2

1The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA; 2The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 3Johns Hopkins University, Baltimore, Maryland, USA

 

                  1105.    MR-Visible and RF-Safe Low Profile Transmission Line for Active Devices

 

Sascha Krueger1, Karl M. Ruhl2, Elmar Spuentrup2, Sebastian Schmitz3, Steffen Weiss1, Daniel Wirtz1, Arno Buecker4, Oliver Lips1

1Philips Research Europe, Hamburg, Germany; 2University Clinic Aachen, Aachen, Germany; 3Fraunhofer Institute for Production Technology, Aachen, Germany; 4University Clinic Saarland, Homburg, Germany

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                  1106.    B0-Field-Driven Capsule Endoscope with Swimming Tails for Propulsion: Design Study

 

Gabor Kosa1, Peter Jakab2, Nobuhiko Hata2

1Technion, Haifa, Israel; 2Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA

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                  1107.    A Novel Device for Image-Guided Interventional Breast Procedures Using 3D Access and Geometry

 

Matthew Smith1, Xu Zhai1, Dharmesh Mahay1, Christopher Westphal1, Ray Harter2, Gale Sisney, MD1, Sean Fain, PhD1

1University of Wisconsin, Madison, Wisconsin, USA; 2Marvel Medtech, LLC, Madison, Wisconsin

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                  1108.    Imaging Characteristics of an MRI-Compatible Stent Delivery System

 

Karl K. Vigen1, Jon Buzzard2, Amish N. Raval1

1University of Wisconsin-Madison, Madison, Wisconsin, USA; 2Cordis Endovascular, Warren, New Jersey, USA

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                  1109.    Performance of Inductively Coupled RF Coils as Reference Markers Under Various Conditions at 1.5 T

 

Robert Trampel1, Harald Busse1, Wilfried Gründer2, Michael Moche1, Thomas Kahn1

1University Hospital Leipzig, Leipzig, Germany; 2University Leipzig, Leipzig, Germany

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                  1110.    Development of an Interventional Endo-MRI: Toward the Therapy of Pancreaticobiliary Diseases

 

Bensheng Qiu1, Joo Ha Hwang1, Jeff Stevenson1, Jenee O'Brien1, Xiaoming Yang1

1University of Washington Medical Center, Seattle, Washington, USA

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                  1111.    Development of a Two-Room MR/OR Suite: Concept to Clinical Implementation

 

Kiaran Patrick McGee1, Kendall H. Lee1, Heidi Ward1, Michael J. Link1, William J. Perkins1, James R. Munis1, Christopher P. Wood1, Robert J. Witte1, John I. Lane1, Fredrick B. Meyer1, John Huston1

1Mayo Clinic, Rochester, Minnesota, USA

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                  1112.    New Devices for Safety and Usability to Introduce Robot Assistance Into Clinical MR-Guided
                              Microwave Ablation of Liver Tumors

 

Shigehiro Morikawa1, Koichiro Murakami1, Sigeyuki Naka1, Yoshimasa Kurumi1, Masahito Morita1, Toshiro Inubushi1, Tsuyoshi Nakakubo2, Kazuo Umihira2, Hasnine A. Haque3, Nobuhiko Hata4

1Shiga University of Medical Science, Ohtsu, Shiga, Japan; 2Umihira Works, Kyoto, Japan; 3GE Yokogawa Medical Systems, Hino, Tokyo, Japan; 4Brigham & Women's Hospital, Boston, Massachusetts, USA

 

                  1113.    Cardiac Specific Plasmid-VEGF Increases Myocardial Angiogenesis, Perfusion and Infarct Resorption

Maythem Saeed1, Alastair Martin1, Phillip Ursell1, Oliver Weber1, Loi Do1, Alexis Jacquier1, Charles Higgins1, David Saloner1

1University of California San Francisco, San Francisco, California, USA

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                  1114.    MRI Based Monitoring of Intervention for Deep Vein Thrombosis

 

Marcus Katoh1, 2, Andrea J. Wiethoff3, Patrick Haage4, Josef Tacke5, Rolf W. Gunther6, Elmar Spuentrup6

1University Hospital Saarland, Homburg, Germany; 2University Hospital RWTH Aachen, Aachen, Germany; 3Philips Medical Systems, Netherlands; 4Helios Hospital Wuppertal, Germany; 5Hospital Passau, Germany; 6University Hospital RWTH Aachen, Germany

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                  1115.    Intraarterial Perfusion to Monitor Endovascular Procedures in MR

 

Ashley D. Harris1, 2, Jayme C. Kosior1, 2, Linda B. Andersen1, 2, Richard Frayne1, 2

1University of Calgary, Calgary, Alberta, Canada; 2Foothills Medical Centre, Calgary Health Region, Calgary, Alberta, Canada

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                  1116.    MR-Guided Electrophysiology Ablations

 

Richard Philip Mallozzi1, Renee Guhde1, Eric Fiveland1, Robert Darrow1, Charles L. Dumoulin1, Ehud J. Schmidt2, Jeremy Dando3, Scott Petersen3, Vivek Y. Reddy4, Aravinda Thiagalingam4, Gotfried F. Holmvang4

1GE Global Research, Niskayuna, New York, USA; 2GE Healthcare, Waukesha, Wisconsin, USA; 3St. Jude Medical, Inc., Minnetonka, Minnesota, USA; 4Massachusetts General Hospital, Boston, Massachusetts, USA

 

                  1117.    Phase Refocusing for Improved Visualization of Interventional Guidewires

William Overall1, Greig Scott1, Yoriyasu Suzuki1, Masahiro Terashima1, Fumiaki Ikeno1, Michael McConnell1, John Pauly1

1Stanford University, Stanford, California, USA

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                  1118.    Relaxation Properties of Cavitation Induced Tissue Lesions

 

Timothy L. Hall1, Gregory R. Lee, Charles A. Cain, Luis Hernandez-Garcia

1University of Michigan, Ann Arbor, Michigan, USA

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                  1119.    An Echo-Dephased SPGR Approach to Generate Positive Contrast Due to Paramagnetic
                              Marker: An Interventional MRI Application

 

Sunil Patil1, Oliver Bieri1, Deniz Bilecen2, Klaus Scheffler1

1University of Basel/University Hospital, Basel, Switzerland; 2University Hospital/University of Basel, Basel, Switzerland

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                  1120.    Passive Catheter Tracking/Visualization Using Frequency Demodulation and IDEAL

 

Orhan Unal1, Ethan K. Brodsky1, Scott B. Reeder1

1University of Wisconsin-Madison, Madison, Wisconsin, USA

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                  1121.    HYPR MR Fluoroscopy

 

Orhan Unal1, Chuck A. Mistretta1

1University of Wisconsin-Madison, Madison, Wisconsin, USA

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                  1122.    Visualization of the Paramagnetic Markers in Interventional MRI Using Spatial-Spectral Pulses

 

Sunil Patil1, Christian Boller1, Deniz Bilecen2, Klaus Scheffler1

1University of Basel/University Hospital, Basel, Switzerland; 2University Hospital/University of Basel, Basel, Switzerland

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                  1123.    Evaluation of Sub-Pixel Fiducial Tracking Using Image Processing

 

Marc A. Rea1, Donald W. McRobbie1, Ian Young2, Haytham Elhawary2, Aleksander Zivanovic2, Michael Lamperth2

1Charing Cross Hospital, London, UK; 2Imperial College London, London, UK

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                  1124.    Motion Compensated Catheter Tracking

 

Carsten Oliver Schirra1, Redha Boubertakh1, 2, Reza Razavi1, Tobias Schaeffter1

1King’s College London, London, UK; 2University College London, London, UK

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                  1125.    Interactive MR Imaging Using Parallel Acquisition and Parallel Reconstruction

 

Eigil Samset1, 2, W. Scott Hoge3, Ferenc Jolesz3

1Brigham and Women's Hospital, Boston, Massachusetts, USA; 2University of Oslo, Oslo, Norway; 3Brigham and Women's Hospital, Massachusetts, USA

 

 

Thermal Therapy

Hall 14.1                     Monday 14:00 - 16:00

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                  1126.    Amide Proton Transfer (APT) Imaging for the Monitoring of Heating Treatment by High
                              Intensity Focused Ultrasound (HIFU): Phantom Experiments

 

Yi-Yu Shih1, Teng-Yi Huang2, Hsu-Hsia Peng1, Hsiao-Wen Chung1, Cheng-Yu Chen3

1National Taiwan University, Taipei, Taiwan; 2National Taiwan University of Science and Technology, Taipei, Taiwan; 3Tri-Service General Hospital, Taipei, Taiwan

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                  1127.    MRI Guided Focused Ultrasound of Moving Organs: Target Tracking with On-Line
                             Anticipation of Periodic Displacements

 

Charles Mougenot1, 2, Baudouin Denis de Senneville1, Mario Ries1, Bruno Quesson1, Chrit Moonen1

1Laboratory for Molecular and Functional Imaging, Bordeaux, Gironde, France; 2Philips Medical Systems, Suresnes, Paris, France

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                  1128.    Three Dimensional Spatial and Temporal Temperature Control with MR-Thermometry
                              Guided Focused Ultrasound

 

Charles Mougenot1, 2, Chrit Moonen1

1Laboratory for Molecular and Functional Imaging, Bordeaux, Gironde, France; 2Philips Medical Systems, Suresnes, Paris, France

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                  1129.    Simultaneous Temperature and Motion Tracking Using HARP MRI [T-HARP]

 

AbdElMonem Mohamed El-Sharkawy1, Khaled Z. Abd-Elmoniem1, Jerry L. Prince1, Paul A. Bottomley1

1Johns Hopkins University, Baltimore, Maryland, USA

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                  1130.    Real-Time Temperature Monitoring Using Line-Scan Phase Measurement

 

Charles L. Dumoulin1, Robert D. Darrow1, Richard P. Mallozzi1

1General Electric Global Research, Niskayuna, New York, USA

 

                  1131.    Feasibility of  Full RF Current-Vector Mapping for MR-Guided RF Ablations

Kim Shultz1, John Pauly1, Greig Scott1

1Stanford University, Stanford, California, USA
 

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                  1132.    MRI Guided Focused Ultrasound of Moving Tissues: Accelerated MR-Thermometry and
                              Motion Analysis for Subsecond Target Tracking

 

Mario Ries1, Gregory Maclair1, Baudouin Denis de Senneville1, Philippe Lourenço De Oliviera1, Charles Mougenot2, Erkki Vahala3, Chrit Moonen1

1Laboratory for Molecular and Functional Imaging, Bordeaux, France; 2Philips Medical Systems, Suresnes, France; 3Philips Medical Systems, Helsinki, Finland

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                  1133.    PRF Shift Thermometry Using Multiple-Acquisition Phase-Cycled Balanced SSFP

 

Viola Rieke1, Brian A. Hargreaves1, Kim Butts Pauly1

1Stanford University, Stanford, California, USA

 

                  1134.    VD K-T Acquisition for Accelerating Temperature Imaging

GuoBin Li1, Yiu-Cho Chung2, Al Zhang1, XiaoDong Zhou1

1Siemens Mindit Magnetic Resonance Ltd., Shen Zhen, Guang Dong, People’s Republic of China; 2Siemens Mediecal Solutions USA, Ohio, USA

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                  1135.    PCA-Based Image Registration for On-Line MR Temperature Monitoring of Moving Tissues

 

Gregory Maclair1, 2, Baudouin Denis de Senneville1, Mario Ries1, Bruno Quesson1, Chrit Moonen1

1Laboratory for Molecular and Functional Imaging, Bordeaux, France; 2LaBRI, Bordeaux, France

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                  1136.    A Temporally Constrained Reconstruction Algorithm Applied to MRI Temperature Data

 

Nick Todd1, Ganesh Adluru, Ed V.R. DiBella, Dennis L. Parker

1University of Utah, Salt Lake City, Utah, USA

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                  1137.    Evaluation of Chronic Cryo Prostate Lesions by Diffusion-Weighted MRI

 

Jing Chen1, Donna Bouley1, M.A.A.J van den Bosch1, Bruce Daniel1, Kim Butts Pauly1

1Stanford University, Stanford, California, USA

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                  1138.    Ice Ball Imaging During Cryoablation of Canine Prostates: Contrast-Enhanced MRI Provides
                             Most Accurate Delineation of the Acute Necrotic Zone

 

Maurice A.A.J. van den Bosch1, Erin H. Liu2, Sonal Josan2, Kim Butts-Pauly2, Donna M. Bouley1, Bruce L. Daniel1

1Stanford University Medical Center, Stanford, California, USA; 2Lucas MRS Imaging Center, Stanford, California, USA

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                  1139.    MRI-Monitoring of Hyperthermia Induced Gadodiamide Release from Long-Circulating
                             Thermosensitive Liposomes in Tumors

 

Michael Peller1, Alenka Schwerdt2, Martin Hossann3, Herbert M. Reinl1, Rolf D. Issels3, 4, Lars Lindner3, 4, M Reiser1

1University Hospital of Munich, Munich, Germany; 2University of Munich, Germany; 3University Hospital of Munich, Germany; 4KKG "Hyperthermia"/GSF-Natl. Research Center for Environment and Health, Germany

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                  1140.    Monitoring Prostate Thermal Therapy with Diffusion-Weighted MRI

 

Jing Chen1, Chris Diederich2, M.A.A.J. van den Bosch1, Bruce Daniel1, Graham Sommer1, Kim Butts Pauly1

1Stanford University, Stanford, California, USA; 2UCSF, San Francisco, California, USA

 

                  1141.    Multifunctional Plasmonic Nanoparticles for Photothermal Therapy of Cancer with MRI Monitoring

Tim Larson1, Douglas Webb2, James A. Bankson2, Konstantin V. Sokolov1, 2

1The University of Texas, Austin, Texas, USA; 2The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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                  1142.    Evaluation of Subacute and Chronic Cryotherapy Lesions Using Histopathology and Contrast
                              Enhanced MR Images in the Dog Prostate Model

 

Donna Michelle Bouley1, Erin Liu1, Kim Butts Pauly1, Maurice Van den Bosch1, Bruce Daniel1

1Stanford University, Stanford, California, USA

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                  1143.    In Vivo Assessment of Canine Prostate Thermal Ablations with Magnetization Transfer Imaging

 

Andrew Bruce Holbrook1, Donna M. Bouley1, Marcus Alley1, Bruce Daniel1, Chris Diederich2, Graham Sommer1, Kim Butts Pauly1

1Stanford University, Stanford, California, USA; 2UCSF, San Francisco, California, USA

 

 

Novel Contrast Agents

Hall 14.1                     Monday 14:00 - 16:00

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                  1144.    Improved Visualization of Intra-Axial Gliomas on Enhanced MR Imaging with Gadobenate

                              Dimeglumine Compared to Gadopentetate Dimeglumine: Implications for Therapeutic Intervention

 

Matthew Joseph Kuhn1, Piero Picozzi2, Kenneth Maravilla3, Marco Essig4, Nicoletta Anzalone2, Kalyani Vallurupalli1

1Southern Illinois University, Springfield, Illinois, USA; 2San Raffaele Hospital, Milan, Italy; 3University of Washington, Seattle, Washington, USA; 4German Cancer Research Institute, Heidelberg, Germany

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                  1145.    A Highly Sensitive MR Contrast Agent Based on Liposomal Nanocarrier Containing

                             Superparamagnetic Iron-Oxide

 

Ketan Ghaghada1, Karl Hagen2, Srinivasan Mukundan1, 3

1Duke University Medical Center, Durham, North Carolina, USA; 2Emory University, Atlanta, Georgia, USA; 3Duke University, Durham, North Carolina, USA

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                  1146.    Paramagnetic Dy(III)-Loaded Liposomes as T2 Susceptibility MRI Agents

 

Enzo Terreno1, Claudia Cabella2, Carla Carrera1, Daniela Delli Castelli1, Stefania Lanzardo1, Roberta Mazzon2, Simona Rollet1, Massimo Visigalli2, Silvio Aime1

1University of Torino, Torino, Italy; 2CRM Bracco Imaging S.p.A., Colleretto Giacosa (TO), Italy

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                  1147.    Avidin Induced Clearance of Biotinylated Paramagnetic Liposomes for Improved

                             Magnetic Resonance Molecular Imaging

 

Geralda A.F. van Tilborg1, Willem J.M. Mulder2, Nico A.J.M. Sommerdijk1, Gustav J. Strijkers1, Klaas Nicolay1

1Eindhoven University of Technology, Eindhoven, Netherlands; 2Mount Sinai School of Medicine, New York, USA

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                  1148.    T1 Relaxivity of Liposomal-Encapsulated Gadolinium Contrast Agents: Effect of

                              Particle Size and Gadolinium Concentration

 

Ketan Ghaghada1, Keigo Kawaji2, Catherine Hawley2, Srinivasan Mukundan1, 2

1Duke University Medical Center, Durham, North Carolina, USA; 2Duke University, Durham, North Carolina, USA

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                  1149.    The Applications of Nanoshells and Nanocapsules in Magnetic Resonance Molecular Imaging

 

Chia-Hao Su1, Hwo-Shuenn Sheu2, Yi-Wei Lo3, Jun-Cheng Weng1, Dar-Bin Shieh3, Chen-Sheng Yeh3, Jyh-Horng Chen1

1National Taiwan University, Taipei, Taiwan; 2National Synchrotron Radiation Research Center, Hsinchu, Taiwan; 3National Cheng Kung University, Tainan, Taiwan

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                  1150.    SPIO-Loaded Nano Test Tubes as Ultra-Sensitive MRI Contrast Agents

 

Heather Hillebrenner1, Li Tao2, Chase Kessinger1, Chalermchai Khemtong1, Jimin Ren3, Dean Sherry3, Wenchuang Hu2, Jinming Gao1

1University of Texas Southwestern Medical Center, Dallas, Texas, USA; 2University of Texas at Dallas, Richardson, Texas, USA; 3UT Southwestern Medical Center, Dallas, Texas, USA

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                  1151.    Functional Imaging Using Nitroxides - A Feasibility Study at 11.7T

 

Keerthi Shet1, Gaunglong He2, Jay L. Zweier2

1Ohio State University, Columbus, Ohio, USA; 2Davis Heart and Lung Research Institute, Columbus, Ohio, USA

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                  1152.    Relaxivity of Cobalt Nanoparticles, a Novel MR Contrast Agent

 

Laura Michelle Parkes1, Richard Hodgson1, Le T. Lu2, Ian Robinson2, David Fernig2, Nguyen TK Thanh2

1University of Liverpool, Liverpool, Merseyside, UK; 2University of Liverpool, UK

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                  1153.    MRI Characterization of Iron in Soluble (Ferritin-Like) and Particulate (Hemosiderin-Like) Mixtures

 

Jerry Shing Chung Cheung1, April M. Chow1, Jens H. Jensen2, Haiying Tang3, Truman R. Brown4, Sujit Sheth4, Gary M. Brittenham4, Ed Xuekui Wu1

1The University of Hong Kong, Pokfulam, Hong Kong; 2New York University, New York, USA; 3Merck Research Laboratories, Rahway, New Jersey, USA; 4Columbia University, New York, USA

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                  1154.    Controlled Aggregation of Ferritin for MRI of Actin Polymerization

 

Kevin M. Bennett1, Erik M. Shapiro2, Christopher H. Sotak3, Alan P. Koretsky1

1National Institutes of Neurological Disease and Stroke, Bethesda, Maryland, USA; 2Yale University, New Haven, Connecticut, USA; 3Worcester Polytechnic University, Worcester, Massachusetts, USA

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                  1155.    A Novel Class of Vanadium-Based MRI Contrast Agents Specific for Highly Glycolytic Cancer Cells

 

Devkumar Mustafi1, Walter J. Liszewski1, Reba Mustafi1, Marc B. Bissonnette1, Elizabeth Peng1, Gregory S. Karczmar1, John W. Ejnik2, Heather Martin2

1The University of Chicago, Chicago, Illinois, USA; 2Northern Michigan University, Marquette, Michigan, USA

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                  1156.    A Novel Low Molecular Weight Folate Receptor Targeted Contrast Agent for Magnetic

                              Resonance Tumour Imaging

 

Tammy Louise Kalber1, Nazila Kamaly, Mahamoud Omar Hussein, Michael Rael Jorgensen, Po-Wah So1, Jimmy David Bell1, Andrew David Miller

1Hammersmith Hospital, Imperial College London, London, UK

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                  1157.    Folate Targeted Paramagnetic Liposomes for Magnetic Resonance Tumour Imaging

 

Nazila Kamaly1, Tammy Louise Kalber2, Maya Thanou1, Po-Wah So2, Jimmy David Bell2, Andrew David Miller1

1Imperial College London, London, UK; 2Hammersmith Hospital, Imperial College London, London, UK

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                  1158.    Collagen Binding MR-Detectable Liposomes

 

H. M.H.F. Sanders1, Maarten Merkx1, Anita Mol1, Willem J. Mulder, 12, Gustav J. Strijkers1, Klaas Nicolay1

1Eindhoven University of Technology, Eindhoven, Netherlands; 2Mount Sinai School of Medicine, New York, USA

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                  1159.    Cancer Detection in Mice Using Dendrimeric Gd-Peptide Nucleic Acid-Peptide Molecular Probes

 

Nariman Amirkhanov1, Mohan Aruva1, Kaijun Zhang1, Ivan Emilov Dimitrov2, Song Lai1, Christopher Cardi1, Mathew Thakur1, Eric Wickstrom1

1Thomas Jefferson University, Philadelphia, Pennsylvania, USA; 2Philips Medical Systems, Best, Netherlands

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                  1160.    Targeting Tumor Cells with Gd(III) Chelates by Means of the Glutamine Transporting System

 

Alessandro Barge1, 2, Lorenzo Tei3, Simonetta Geninatti Crich4, 5, Rachele Stefanìa4, Michaela Forsterova4, Stefania Lanzardo4, Anna Ciampa4, Giancarlo Cravotto1, Silvio Aime4

1University of Torino, Torino, Italy, Italy; 2CIM - Center for Molecular Imaging, Torino, Italy; 3Università del Piemonte Orientale, Alessandria, Italy, Italy; 4University of Torino, Italy; 5CIM -Center for Molecular Imaging,

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                  1161.    MR Contrast Agent Coupled to an Antisense Peptide Nucleic Acid - Cell Penetrating Peptide Conjugate

 

Joern Engelmann1, Wu Su1, Ritu Mishra1, Josef Pfeuffer2, Karl-Heinz Wiesmueller3, Kamil Ugurbil1, 4

1Max Planck Institute for Biological Cybernetics, Tübingen, Germany; 2Siemens Medical Solutions, Erlangen, Germany; 3EMC Microcollections GmbH, Tübingen, Germany; 4University of Minnesota, Minneapolis, Minnesota, USA

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                  1162.    In Vitro Mitochondrial Labeling Using Mito-Carboxy Proxyl (Mito-CP) Enhanced

                             Magnetic Resonance Imaging

 

Douglas Edward Prah1, Eric Scott Paulson1, Jacek Zielonka1, Micael J. Hardy1, Joy Joseph1, Balaraman Kalyanaraman1, Kathleen Marie Schmainda1

1Medical College of Wisconsin, Milwaukee, Wisconsin, USA

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                  1163.    A New Lectin-Targeted Contrast Agent for MR and Optical Molecular Imaging of Vascular Endothelium

 

Arvind P. Pathak1, Yoshinori Kato1, Jiangyang Zhang1, Melina Jones1

1The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

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                  1164.    Feasibility of cNGR Labeled Paramagnetic Quantum Dots for Molecular Magnetic
                              Resonance Imaging and Two Photon Laser Scanning Microscopy of Neovascularization

 

Marlies Oostendorp1, 2, Kim Douma2, Bram J. Stelt2, Tilman M. Hackeng2, Anouk Dirksen2, Marc A. van Zandvoort2, Mark J. Post2, Walter H. Backes1, 2

1Maastricht University Hospital, Maastricht, Netherlands; 2Maastricht University, Maastricht, Netherlands

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                  1165.    A Novel Gd-Based MRI Contrast Agent Responsive to the Factor XIII Transglutaminase Activity

 

Lorenzo Tei1, 2, Alessandro Barge, 2, Dario Longo, 2, Linda Chaabane3, Luigi Miragoli3, Vito Lorusso3, Giancarlo Cravotto, Silvio Aime, 2

1University of Eastern Piedmont, Alessandria, Italy; 2CIM – Center for Molecular Imaging, University of Torino, Torino, Italy; 3Bracco Imaging S.p.A., Milano, Italy

 

                  1166.    A New Bio-Activated Paramagnetic Gadolinium(III) Complex [Gd(DOTA-FPG)] for Tracing Gene Expression

Yun-Ming Wang1, Yu-Ton Chang1, Yu-Zheng Su1, Tian-Lu Cheng1, Jui-Sheng Hsu2, Gin-Chung Liu, 13

1Kaohsiung Medical University, Kaohsiung, Taiwan; 2Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung, Taiwan; 3Kaohsiung Medical University Hospital, Kaohsiung, Taiwan

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                  1167.    Novel Solubility Switch Contrast Agents: In Vivo Detection of MMP-7 Activity

 

Martin Lepage1, William C. Dow2, Marco Melchior2, Ying You2, Barbara Fingleton3, C Chad Quarles4, John C. Gore4, Lynn M. Matrisian3, J Oliver McIntyre3

1Université de Sherbrooke, Sherbrooke, Québec, Canada; 2Alerion Biomedical Inc., San Diego, California, USA; 3Vanderbilt University, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA; 4Vanderbilt University, Nashville, Tennessee, USA

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                  1168.    Quantification of Release of Thermosensitive Liposome-Encapsulated Gadodiamide

 

Tungte Wang1, Martin Hossann1, Herbert M. Reinl1, Michael Peller1, Maximilian Reiser1, Rolf D. Issels1, Lars H. Lindner1

1University Hospital Grosshadern, Ludwig-Maximilians-University, Munich, Bavaria, Germany

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                  1169.    A Novel Generation of Concentration Independent Gd(III)-Based MRI Responsive Agents

 

Enzo Terreno1, Alberto Bert1, Mauro Botta2, Walter Dastrù1, Alberto Sanino1, Silvio Aime1

1University of Torino, Torino, Italy; 2University Eastern Piedmont, Alessandria, Italy

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                  1170.    Towards the Detection of Hepatocellular Carcinoma with a pH-Responsive Dendritic MRI Contrast Agent

 

Md. Meser Ali1, Mark D. Pagel1

1Case Western Reserve University, Cleveland, Ohio, USA

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                  1171.    Increased Sensitivity of 19F MR of Perfluoro-Emulsions Using Lanthanide Chelates for T1 Shortening

 

Rolf Lamerichs1, René Wegh1, Dirk Burdinski1, Sander Langereis1, Holger Grüll1

1Philips Research, Eindhoven, Netherlands

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                  1172.    Selectively Dissolvable Manganese/Alginate Microcapsules for Novel Drug Delivery

                              Strategies and Positive Contrast Imaging at 3T

 

Partha Hota1, Brad P. Barnett1, Yahel Har-el1, Pitor Walczak1, D Qian1, H B. Na2, J. H. Lee3, K An2, T. Hyeon2, George Sgouros1, Jeff W. Bulte1, Philippe Gailloud1, Aravind Arepally1

1The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 2Seoul National University, Republic of Korea; 3Sungkyunkwan University School of Medicine, Republic of Korea

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                  1173.    In Vivo Molecular MRI of Mouse Embryonic Stem Cell Viability

 

Phillip C. Yang1, Esther Xie1, Pratima Kundu1, William Stein1, Micha Drukker1, Irving Weissman1, Joseph Wu1, Robert Robbins1

1Stanford University, Stanford, California, USA

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                  1174.    A New Route to Cellular Labelling

 

Eliana Gianolio1, Silvio Aime1, Giovan Battista Giovenzana2, Simonetta Geninatti Crich1, Anna Ciampa1

1University of Torino, Torino, Italy, Italy; 2Università del Piemonte Orientale “A. Avogadro”,

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                  1175.    Manganese Oxide (MnO) Nanoparticles as a New T1 Contrast Agent for MRI

 

Hyon Bin Na1, Jung Hee Lee2, Kwangjin An1, In Su Lee3, Yong Il Park1, Sung Tae Kim2, Sun-Ok Kim4, Taeghwan Hyeon1

1School of Chemical and Biological Engineering, Seoul, Republic of Korea; 2Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; 3Kyunghee University, Yongin, Republic of Korea; 4Samynag R&D Center, Daejeon, Republic of Korea

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                  1176.    A Novel Generation of Improved LIPOCEST MRI Agents with Highly Shifted Intraliposomal Water Protons

 

Daniela Delli Castelli1, Claudia Cabella2, Carla Carrera1, Roberta Mazzon2, Simona Rollet1, Joseph Stancanello2, Enzo Terreno1, Massimo Visigalli2, Silvio Aime1

1University of Torino, Torino, Italy; 2CRM Bracco Imaging S.p.A., Colleretto Giacosa (TO), Italy

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                  1177.    pH Measurement with a MRI-PARACEST Contrast Agent: Nd-DOTAM-Gly-Lys

 

Alex Xuexin Li1, 2, Craig K. Jones1, Mojmir Suchy2, Filip Wojciechowski2, Robert H.E. Hudson2, Ravi S. Menon1, 2, Robert Bartha1, 2

1Robarts Research Institute, London, Ontario, Canada; 2The University of Western Ontario, London, Ontario, Canada

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                  1178.    A New MRI PARACEST Agent for Sensing Glucose

 

Jimin Ren1, Eul Hyun Suh1, Zoltan Kovacs1, 2, Allen Dean Sherry1, 2

1University of Texas, Southwestern Medical Center, Dallas, Texas, USA; 2University of Texas at Dallas, Richardson, Texas, USA

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                  1179.    Detection of MRI Contrast Based on Chemical Exchange Saturation Transfer (CEST) in the

                              Presence of the T2/T2* Contrast Agent Feridex

 

Assaf A. Gilad1, Hanneke W.M. van Laarhoven2, Michael T. McMahon1, 3, Piotr Walczak1, Arend Heerschap2, Michal Neeman4, Peter C.M. van Zijl1, 3, Jeff W.M. Bulte1

1Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 2Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; 3Kennedy Krieger Institute, Baltimore, Maryland, USA; 4The Weizmann Institute of Science, Rehovot, Israel

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                  1180.    Multi-Colored Nano-CEST MRI Contrast Particles for Cell Imaging

 

Michael T. McMahon1, 2, Yahel Har-el1, Assaf A. Gilad1, Jason M. Zhao1, George Sgouros1, Jeff W.M. Bulte1, Peter C.M. vanZijl1, 2

1Johns Hopkins School of Medicine, Baltimore, Maryland, USA; 2Kennedy Krieger Institute, Baltimore, Maryland, USA

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                  1181.    A PARACEST MRI Contrast Agent That Detects Esterase Enzymes

 

Yuguo Li1, Guanshu Liu1, Mark D. Pagel1

1Case Western Reserve University, Cleveland, Ohio, USA

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                  1182.    Towards ParaCEST MRI Contrast Agents Without Coordinated Water: Lanthanide

                              Complexes of Novel Acetamido-Substituted Diethylenetriamine- And Triethylenetetramine Ligands

 

Dirk Burdinski1, Johan Lub1, Jeroen A. Pikkemaat1, René T. Wegh1, Holger Grüll1, Lidia Nieto Garrido1, Séverine G. Girard1, Sophie Martial1, Carolina Del Pozo Ochoa1, Diana Moreno Jalón1, Thomas Weyhermüller2

1Philips Research Europe, Eindhoven, Netherlands; 2Max Planck Institute for Bioinorganic Chemistry, Mülheim a. d. Ruhr, Germany

 

 

Molecular Imaging Applications

Hall 14.1                     Monday 14:00 - 16:00

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                  1183.    T2* Quantification Can Differentiate Alzheimer’s Plaques Burden Following Anti-Amyloid Therapy

 

Youssef Zaim Wadghiri1, Moustafa Douadi1, Henrieta Scholtzova1, Thomas Wisniewski1

1NYU School of Medicine, New York, USA

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                  1184.    In Vivo MR Imaging of Human Glioblastoma Cell Derived Tumor by Using Anti MT1-MMP

                              Antibody Conjugated Ultrasmall Superparamagnetic Iron Oxides (USPIOs)

 

Bo-Hyung Park1, Jae-Chang Chung1, Man-Il Huh1, Young-Ju Lee1, In-Seong Kim1, Joo-Hyun Kim1, Yongmin Chang, 12

1Kyungpook National University, Daegu, Republic of Korea; 2Kyungpook National University Hospital, Daegu, Republic of Korea

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                  1185.    Targeted Imaging of Breast Cancer Brain Metastasis Using Antibody Labeled Manganese

                              Oxide (MnO) Nanoparticles

 

Yoo Jeong Yim1, Hyon Bin Na2, Ji-Sun Baek1, Yong Il Park2, Kwangjin An2, Do-Hyun Nam1, Sung Tae Kim1, Keun-Ho Lim3, Jung Hee Lee1, Taeghwan Hyeon2

1Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; 2School of Chemical and Biological Engineering, Seoul, Republic of Korea; 3Asan Institutes for Life Science, University of Ulsan, Seoul, Republic of Korea

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                  1186.    In Vivo Characterization of the Pharmacokinetics of Perfluorocarbon Nanoparticles in a Mouse

                              Model Using 19F MRS

 

Jacob Wheatley Myerson1, Xiaoxia Yang1, Anne Morawski Neubauer1, Emily Alex Waters1, Greg M. Lanza1, Samuel A. Wickline1, Junjie Chen1

1Washinton University, Saint Louis, Missouri, USA

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                  1187.    High-Resolution 3D MRI Mapping of  Tumor Angiogenesis Using α 5β 1-Targeted

                              Perfluorocarbon Nanoparticles

 

Anne H. Schmieder1, Todd A. Williams1, John S. Allen1, Grace Hu1, Huiying Zhang1, Shelton D. Caruthers1, 2, Samuel A. Wickline1, Gregory M. Lanza1

1Washington University Medical School, St. Louis, Missouri, USA; 2Philips Medical Systems, Cleveland, Ohio, USA

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                  1188.    Use of Highly Sensitive Dual Probes Gd-Liposome and Gd-Loaded Apoferritin for

                              Targeting Tumor Angiogenesis for MR-Visualization and Drug Delivery

 

Lorenzo Tei1, 2, Simonetta Geninatti Crich, 2, Benedetta Bussolati, Anna Ciampa, 2, Cristina Grange, Diego Alberti, 2, Stefania Lanzardo, 2, Giovanni Camussi, Silvio Aime, 2

1University of Eastern Piedmont, Alessandria, Italy; 2CIM – Center for Molecular Imaging, University of Torino, Torino, Italy

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                  1189.    Investigation of a Carcinoma-Specific SPIO-Antibody Conjugate for MR Visualisation of Epithelial Tumours

 

Panagiotis Kyrtatos1, Kim Vigor2, Jack Wells1, Kenneth Cheung1, David G. Gadian1, Kerry Chester2, Mark Lythgoe1

1UCL Institute of Child Health, London, UK; 2Royal Free and University College Medical School, London, UK

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                  1190.    Magnetic Resonance Imaging of Delivery Multifunctional Liposomes with Novel Peptide

                              Ligand Targeted to Breast Cancer Vasculature

 

Maria Mikhaylova1, Amin Hajitou2, Saraswati Sukumar3, Yoshinori Kato1, Dmitri Artemov1, Wadih Arap2, Renata Pasqualini2, Zaver M. Bhujwalla1

1JHU ICMIC Program, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 2The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA; 3Johns Hopkins University, Breast Cancer Program, Baltimore, Maryland, USA

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                  1191.    Molecular Magnetic Resonance Imaging (MRI) of Surface-Epithelial-Derived Protein

                             CA125 in Human Ovarian Carcinoma Cells Using Superparamagnetic Immunomicelles

 

Brian A. Larsen1, Kristen M. Scaff2, Michael A. Haag1, Natalie J. Serkova2, Kenneth R. Shroyer2, Conrad R. Stoldt1

1University of Colorado, Boulder, Colorado, USA; 2University of Colorado Health Science Center, Denver, Colorado, USA

 

 

Molecular Imaging: Imaging of Cell Migration

Hall 14.1                     Monday 14:00 - 16:00

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                  1192.    Iron Oxide Labeling of Primary Rat Monocytes Using Magneto Electroporation

 

Raoul David Oude Engberink1, Piotr Walczak2, H E. de Vries3, Erwin L. Blezer1, Jeff Bulte2

1University Medical Center Utrecht, Utrecht, Netherlands; 2Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 3VU Medical center, Amsterdam, Netherlands

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                  1193.    Magnetofection Accelerates the Loading of SPIO Nanoparticles for MRI Cell Tracking

 

Amit S. Marwah1, Richard G. Spencer1, Kenneth W. Fishbein1

1National Institutes of Health, Baltimore, Maryland, USA

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                  1194.    Cancer Cells Induce Lymphatic Endothelial Cell Migration

 

Maria Mikhaylova1, Noriko Mori1, Barjor Gimi2, Piotr Walczak3, Jeff W. M. Bulte3, Arvind P. Pathak1, Zaver M. Bhujwalla1

1JHU ICMIC Program, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 2University of Texas Southwestern Medical Center, Dallas, Texas, USA; 3Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA

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                  1195.    MRI Quantification of USPIO-Labeled Cell Density and Number

 

Jerry Shing Chung Cheung1, April M. Chow1, Hung Fat Tse1, Ed Xuekui Wu1

1The University of Hong Kong, Pokfulam, Hong Kong

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                  1196.    Electrophysiological Properties of the Effect of USPIO-Labeling on Embryonic Stem Cells

 

April Mei Kwan Chow1, Yau-Chi Chan2, Yee-Man Lau2, Jerry Shing Chung Cheung1, Tracy Yee Mau Chow1, Hung-Fat Tse2, Ed Xuekui Wu1

1The University of Hong Kong, Pokfulam, Hong Kong; 2The University of Hong Kong, Hong Kong

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                  1197.    Efficiency of Cell Labeling with Different Perfluoro-15-Crown-5 Ether Nanoparticles for 19F MRI

 

Jesus Ruiz-Cabello1, 2, Piotr Walczak3, Vadappuram P. Chacko3, Dorota A. Kedzioreck3, Anne H. Schmieder4, Sam A. Wickline4, Gregory M. Lanza4, Jeff W.M. Bulte3

1Johns Hopkins University Medical School, Baltimore, Maryland, USA; 2Universidad Complutense Madrid, Spain; 3Johns Hopkins University Medical School, Maryland, USA; 4Washington University Medical School, Missouri, USA

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                  1198.    Manganese Guided Cellular MRI of Human Embryonic Stem Cell Viability

 

Mayumi Yamada1, Pratima Kundu1, Micha Drukker1, Irving L. Weissman1, Robert C. Robbins1, Phillip C. Yang1

1Stanford University, Stanford, California, USA

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                  1199.    Migration of SPIO Labled EPCs and Angiogenic Factors

 

Ali S. Arbab1, Robert A. Knight2, ASM Iskander1, Ali M. Rad1, Stasia A. Anderson3, Sunil D. Pandit3, Elizabeth J. Read3, Joseph A. Frank3

1Henry Ford health System, Detroit, Michigan, USA; 2Henry Ford Health System; 3National Institutes of Health,

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                  1200.    Microcapsules Used in Cell Based Therapy Were Designed for Post Implantation Tracking

 

Barjor Gimi1, 2, Timothy Leong3, David Gracias3, Zaver M. Bhujwalla2

1The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA; 2The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 3Johns Hopkins University, Baltimore, Maryland, USA

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                  1201.    Fluorine-19 MRI for Visualization and Quantification of Cell Migration in a Diabetes Model

 

Mangala Srinivas1, Penelope A. Morel2, Lauren A. Ernst1, Jelena Janjic1, Deepak Kadayakkara1, David H. Laidlaw3, Eric T. Ahrens1

1Carnegie Mellon University, Pittsburgh, Pennsylvania, USA; 2University of Pittsburgh, Pittsburgh, Pennsylvania, USA; 3Brown University, Providence, Rhode Island, USA

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                  1202.    Magnetically Labeled Sensitized Splenocytes to Identify Glioma by MRI

 

Ali S. Arbab1, Ali M. Rad1, ASM Iskander1, Kourosh Jafari-Khouzani1, Stephen L. Brown1, Guangliang Ding1, Jiang Quan1, Hamid Soltanian-Zadeh1, Donald J. Peck1

1Henry Ford Health System, Detroit, Michigan, USA

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                  1203.    In Vivo Cell Tracking Using Micron-Sized Iron Oxide Particle (MPIO) Labeling in Rat Model of

                             Liver Tumor Metastasis

 

Jerry Shing Chung Cheung1, April M. Chow1, Kwan Man1, S F. Fan1, Ed Xuekui Wu1

1The University of Hong Kong, Pokfulam, Hong Kong

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                  1204.    Cellular MRI of Monocyte Infiltration: In Vitro Vs In Vivo Labeling

 

Raoul David Oude Engberink1, Erwin L. Blezer1, Erik I. Hoff2, Susanne van der Pol3, H E. de Vries3

1University Medical Center Utrecht, Utrecht, Netherlands; 2Department of Neurology, Maastricht, Netherlands; 3VU Medical center, Amsterdam, Netherlands

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                  1205.    In Vivo Identification of Iron-Marked Cells in the Heart by Gadolinium-Enhanced MRI in a

                             Single Breath-Hold

 

Dirk Cleppien1, Georg Horstick1, Angelica Karpi1, Marion Bug1, Nico Abegunewardene1, Marcus Vosseler1, Wolfgang Schreiber1

1Mainz University Medical School, Mainz, Germany

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                  1206.    Track Brain Tumor Growth by MRI and Planar Bioluminescence Imaging

 

Kemi Cui1, Xiaoyin Xu1, Kelvin Wong1, Hong Zhao2, Jinmin Zhu3, Santosh Kesari2, Stephen TC Wong2, 4

1Brigham and Women's Hospital, Boston, Massachusetts, USA; 2Brigham and Women's Hospital, Massachusetts, USA; 3Harvard Medical School, Boston, Massachusetts, USA; 4Harvard Medical School, Massachusetts, USA

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                  1207.    Longitudinal Detection of Neuronal Stem Cells Labeled with Two Types of Iron Oxide Particles

 

Sergey Magnitsky1, Evangelia I. Zacharaki1, Ragini Verma1, Raquel M. Walton1, John H. Wolfe1, 2, Harish Poptani1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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                  1208.    Pancreatic Islet Graft Monitoring by Magnetic Resonance Imaging in Non-Human Primates

 

Prashanth Vallabhajosyula1, Zdravka Medarova1, Bruce Jenkins1, Natalia Evgenov1, Atsushi Hirakata1, Kazuhiko Yamada1, David Sachs1, Anna Moore1

1Massachusetts General Hospital, Charlestown, Massachusetts, USA

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                  1209.    Clinical Field-Strength MRI of Transplanted Pancreatic Islets in a Large Animal Model

 

Zdravka Medarova1, Prashanth Vallabhajosyula1, Bruce Jenkins1, Natalia Evgenov1, Atsushi Hirakata1, Kazuhiko Yamada1, David Sachs1, Anna Moore1

1Massachusetts General Hospital, Charlestown, Massachusetts, USA

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                  1210.    MRI and PET Dual Detection of Embryonic Stem Cells Grafted in the Myocardium

 

Hualei Zhang1, Hui Qiao1, Datta Ponde1, Fabao Gao1, Hank Kung1, Victor Ferrari1, Rong Zhou1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA

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                  1211.    In Vivo Labeling of Adult Neural Progenitors with Micron Sized Particles of Iron Oxide:

                             Quantitation of Labeled Cell Type

 

James P. Sumner1, Erik M. Shapiro2, Dragan Maric1, Alan P. Koretsky1

1NINDS, Bethesda, Maryland, USA; 2Yale University School of Medicine, New Haven, Connecticut, USA

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                  1212.    Longitudinal Tracking of Recipient Macrophages in Chronic Cardiac Rejection with

                              Non-Invasive In Vivo MRI Using Micrometer-Sized Paramagnetic Iron Oxide (MPIO) Particles

 

Qing Ye1, Yijen Lin Wu1, Lesley M. Foley1, T Kevin Hitchens1, Haval Shirwan2, Chien Ho1

1Carnegie Mellon University, Pittsburgh, Pennsylvania, USA; 2University of Louisville, Louisville, Kentucky, USA

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                  1213.    Novel Radiopaque and MR-Visible Intracellular Contrast Agents for Cell-Tracking and

                              Viability Enhancement of Human Pancreatic β-Islets

 

Partha Hota1, Brad P. Barnett1, Jesus Ruiz-Cabello1, Cal Lauzon1, Piotr Walczak1, Vadappuram P. Chacko1, Aravind Arepally1, Jeff WM Bulte1

1The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

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                  1214.    IIn Vivo Cell Tracking 19F MRI using Perfluorocrown Ether Nanoparticles

 

Jesus Ruiz-Cabello1, 2, Piotr Walczak1, Vadappuram P. Chacko1, Dorota A. Kedzioreck1, Anne H. Schmieder3, Sam A. Wickline3, Gregory M. Lanza3, Jeff W.M. Bulte1

1Johns Hopkins University Medical School, Baltimore, Maryland, USA; 2Universidad Complutense Madrid, Madrid, Spain; 3Washington University Medical School, Missouri, USA

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                  1215.    Detection of Reactive Gliosis Using Manganese-Enhanced MRI (MEMRI)

 

Yuko Kawai1, Ichio Aoki2, Noriko Matsumoto1, Masahiro Umeda1, Toshihiro Higuchi1, Jeff Kershaw2, Afonso C. Silva3, Chuzo Tanaka1

1Meiji University of Oriental Medicine, Kyoto, Japan; 2National Institute of Radiological Sciences, Chiba, Japan; 3NIH,

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                  1216.    Positive Contrast MRI of Magnetically Labeled Human Cervical Carcinoma Cells and Tumor Monitoring

 

Young Beom Kim1, Ki Hyun Bae1, Seung-Schik Yoo2, Tae Gwan Park1, HyunWook Park1

1Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea; 2Harvard Medical School, Boston, Massachusetts, USA

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                  1217.    In Vivo Tracking of Solitary Cells as a Tool for Comparing the Behaviour of Two

                              Metastatically-Distinct Cell Lines in a Mouse Model of Breast Cancer Metastasis to the Brain

 

Soha Said Ramadan1, 2, Lisa T. MacKenzie2, 3, Diane Palmieri4, Patricia S. Steeg4, Ann F. Chambers2, 3, Brian K.

Rutt1, 2, Paula J. Foster1, 2

1Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada; 2Medical Biophysics, University of Western Ontario, London, Ontario, Canada; 3London Regional Cancer Centre, London, Ontario, Canada; 4Women’s Cancers Section, Laboratory of Molecular Pharmacology, Center for Cancer Research, NCI, Bethesda, Maryland, USA

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                  1218.    In Vivo MR Imaging of the  Evolution of the Immune Response in Type 1 Diabetes Progression

 

Zdravka Medarova1, Bingue Han2, Pere Santamaria2, Natalia Evgenov1, Anna Moore1

1Massachusetts General Hospital, Charlestown, Massachusetts, USA; 2Julia McFarlane Diabetes Research Center, Calgary, Alberta, Canada

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                  1219.    In Vivo Detection, Tracking and Quantitation of SPIO-Labeled Dendritic Cells in the

                              Mouse Lymphatic System

 

Jonatan Snir1, Brad Shrum1, Elizabeth Dunn1, Brian K. Rutt1, Greg Dekaban1, Peta O'Connell1, Paula J. Foster1

1Robarts Research Institute, London, Ontario, Canada

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                  1220.    Stroma Fibroblasts are Recruited Systemically to Contribute to the Tumor Angiogenic Rim:

                              Cell Tracking by MRI and Two Photon Microscopy

 

Dorit Granot1, Yoseph Addadi1, Vyacheslav Kalchenko1, Michal Neeman1

1Weizmann Institute of Science, Rehovot, Israel

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                  1221.    Iron Oxide Incorporation for Cell Tracking Does Not Prevent Osteogenic, Chondrogenic or

                             Adipogenic Differentiation of Mesenchymal Stem Cells But Does Affect Extracellular

                             Matrix Patterns and Gene Expression

 

Eric Farrell1, 2, Piotr A. Wielopolski1, Holger Jahr1, Jan Verhaar1, Harrie Weinans1, Gabriel P. Krestin1, Fergal J. O'Brien3, Patrick J. Prendergast2, Gerjo J.V.M. van Osch1, Monique R. Bernsen1

1Erasmus MC, Rotterdam, Netherlands; 2Trinity Centre for Bioengineering, Trinity College Dublin, Dublin, Ireland; 3Royal College of Surgeons in Ireland, Dublin, Ireland

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                  1222.    Cellular MRI of Neural Stem Cell Therapy in a Rat Glioma Model

 

Cecilie Brekke1, 2, Jasdeep Sandhu2, Andrew Lowe2, Thomas Meade3, Jack Price2, Steven Williams2, Michel Modo2

1University of Bergen, Bergen, Norway; 2King's College London, London, UK; 3Northwestern University, Chicago, Illinois, USA

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                  1223.    In Vivo Morphological and Parametric Analysis of Stem Cell Migration on MRI: Investigation of

                             Viable and Non-Viable Behavior

 

Jennifer A. Flexman1, Donna J. Cross1, 2, Takahiro Sasaki1, Yongmin Kim1, Satoshi Minoshima1

1University of Washington, Seattle, Washington, USA; 2University of Michigan, Ann Arbor, Michigan, USA

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                  1224.    Optimized MRI Parameters for Positive Contrast Detection of Iron-Oxide Labeled Cells Using

                              Double-Echo Ultra-Short Echo Time (D-UTE) Sequences

 

Bram F. Coolen1, 2, Philip Lee1, Borys Shuter3, Xavier Golay1, 4

1Singapore Bioimaging Consortium, Singapore, Singapore; 2Eindhoven University of Technology, Eindhoven, Netherlands; 3National University Hospital, Singapore, Singapore; 4National Neuroscience Institute, Singapore, Singapore

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                  1225.    Positive Contrast Imaging of Micron-Sized Iron Oxide Particles

 

Angus Zoen Lau1, Charles Henry Cunningham1

1University of Toronto, Toronto, Ontario, Canada

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                  1226.    Off-Resonance Saturation Method to Enhance SPIO Contrast in Molecular Imaging of Cancer

 

Jinming Gao1, Chase Kessinger1, Chalermchai Khemtong1, Jimin Ren1, Dean Sherry1

1UT Southwestern Medical Center, Dallas, Texas, USA

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                  1227.    Fast Low Angle Positive Contrast Steady-State Free Precession (FLAPS) Imaging: Theory and Experiment

 

Rohan Dharmakumar1, Ioannis Koktzoglou1, Debiao Li1

1Northwestern University, Chicago, Illinois, USA

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                  1228.    Suppression of Large Scale Susceptibility Artifacts in Positive Contrast Images

 

Hannes Dahnke1, Wei Liu2, Jospeh A. Frank3, Tobias Schaeffter4

1Philips Research Europe, Hamburg, Germany; 2Philips Research North America, Briarcliff, New York, USA; 3National Institutes of Health, Bethesda, Maryland, USA; 4King's College, London, UK

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                  1229.    Monitoring the Fate of Iron-Labeled Metastatic Melanoma Cells within the Mouse Lymphatic System

 

Paula J. Foster1, Elizabeth Dunn1, Alfred Harvey2, Kristina Karl2, Colleen M. Nycz2, Ron J. Pettis2

1Robarts Research Institute, London, Ontario, Canada; 2Becton Dickinson Technologies, Research Triangle Park, North Carolina, USA

 

 

Chemical Shift Imaging

Hall 14.1                     Monday 14:00 - 16:00

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                  1230.    Spatio-Spectral Non-Linear Filtering of Spectroscopic Imaging: Increasing Signal-To-Noise

                              Ratio While Preserving Spatial and Spectral Structures

 

Yoshitaka Bito1, Satoshi Hirata1, Yo Taniguchi1, Toru Shirai1, Hisaaki Ochi1

1Hitachi, Ltd., Kokubunji-shi, Tokyo, Japan

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                  1231.    High-Resolution Spectroscopic Imaging with Statistical Reconstruction

 

Justin P. Haldar1, Diego Hernando1, Matthew D. Budde2, Qing Wang2, Sheng-Kwei Song2, Zhi-Pei Liang1

1University of Illinois at Urbana-Champaign, Urbana, Illinois, USA; 2Washington University, St. Louis, Missouri, USA

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                  1232.    Self Rewinding Trajectories for Spectroscopic Imaging

 

Claudiu Schirda1, 2, Fernando Boada2

1University of Pittsburgh, Pittsburgh, Pennsylvania, USA; 2UPMC, Pittsburgh, Pennsylvania, USA

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                  1233.    Correcting for Center Frequency Variations in MRSI Data Using the Partially Suppressed Water Signal

 

Lawrence P. Panych1, 2, Joseph R. Roebuck1, 2, Nan-Kuei Chen1, 2

1Brigham and Women's Hospital, Boston, Massachusetts, USA; 2Harvard Medical School, Boston, Massachusetts, USA

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                  1234.    Fast Nosological Imaging of 2DTSI Brain Data Using Canonical Correlation Analysis

 

Teresa Laudadio1, M. Carmen Martinez-Bisbal2, Bernardo Celda2, Sabine Van Huffel3

1Consiglio Nazionale delle Ricerche, Bari, Italy; 2Universitat de Valencia, Valencia, Spain; 3Katholieke Universiteit Leuven, Leuven, Belgium

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                  1235.    A High Spatial Resolution 1H Magnetic Resonance Spectroscopic Imaging Technique for

                             Breast Cancer with a Short Echo Time

 

Jiani Hu1, Yingjian Yu1, Quan Jiang2, Yang Xuan1, Tao Li1, vivek Sehgal1, Cassann Blake1, Renate Soulen1

1Wayne State University, Detroit, Michigan, USA; 2Henry Ford Hospital, Detroit, Michigan, USA

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                  1236.    Acquisition-Weighted CSI with a Small Number of Scans

 

Rolf Pohmann1, Kamil Ugurbil1, 2

1Max-Planck-Institute for Biological Cybernetics, Tübingen, Germany; 2University of Minnesota, Minneapolis, Minnesota, USA

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                  1237.    Spatially Resolved Measurement of Bone Marrow Fat Content and Unsaturation Index Via

                              Spectroscopic MR Imaging

 

Catherine Jones1, Suzanne L. Wehrli2, Jeremy Magland1, Felix W. Wehrli1

1University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA; 2Children's Hospital of Philadelphia, Pennsylvania, USA

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                  1238.    Mapping T2 Relaxation Time of Cerebral Metabolites Using Proton-Echo Planar Spectroscopic

                             Imaging (PEPSI)

 

Shang-Yueh Tsai1, Stefan Posse2, 3, Yi-Ru Lin4, Cheng-Wen Ko5, Ricardo Otazo3, Hsiao-Wen Chung1, Fa-Hsuan Lin6, 7

1National Taiwan University, Taipei, Taiwan; 2University of New Mexico School of Medicine, Albuquerque, New Mexico, USA; 3University of New Mexico, Albuquerque, New Mexico, USA; 4National Taiwan University of Science and Technology, Taipei, Taiwan; 5National Sun Yat-Sen University, Kaohsiung, Taiwan; 6MGH-HMS-MIT Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA; 7Massachusetts General Hospital, Boston, Massachusetts, USA

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                  1239.    Improved Coverage of Brain Tumors with 1H MRSI Using Cosine Modulated Very Selective

                             Suppression Pulses at 3T

 

Joseph Anthony Osorio1, Duan Xu1, Charles H. Cunningham2, Albert P. Chen1, John M. Pauly3, Daniel B. Vigneron1, Sarah J. Nelson1

1University of California, San Francisco, San Francisco, California, USA; 2University of Toronto, Toronto, Ontario, Canada; 3Stanford University, Palo Alto, California, USA

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                  1240.    Spectroscopic Imaging of the Knee Using an Interleaved Ultrashort TE (UTE) Sequence

 

Jiang Du1, Gavin Hamilton1, Atsushi Takahashi2, Sinha Shantanu1, Christine B. Chung1

1University of California, San Diego, San Diego, California, USA; 2GE Healthcare Technologies, Meno Park, California, USA

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                  1241.    3-D MRSI of Patients with Gliomas Using a 7T Whole Body MR Scanner

 

Sarah J. Nelson1, Duan Xu1, Kathryn E. Hammond1, Janine M. Lupo1, Albert P. Chen1, Charles H. Cunningham2, Douglas A C Kelley3, Susan M. Chang1, John M. Pauly4, Daniel B. Vigneron1

1University of California, San Francisco, California, USA; 2University of Toronto, Toronto, Ontario, Canada; 3GE Healthcare, San Francisco, California, USA; 4Stanford University, Palo Alto, California, USA

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                  1242.    A Magnetic Resonance Spectroscopic Imaging (MRSI) Mapping Technique for Radiotherapy Planning

 

Roberto Garcia-Alvarez1, 2, Gary Liney1, David Manton1, Lindsay Turnbull1

1University of Hull, Hull, UK; 2GE Healthcare, Madrid, Spain

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                  1243.    Fast 3D Proton MR Spectroscopic Imaging of the Human Prostate In Vivo at 3 Tesla Using

                              "Spectroscopic Missing Pulse – SSFP"

 

Christian Schuster1, 2, Tom Scheenen3, Wolfgang Dreher1, 2, Thomas Hambrock3, Arend Heerschap3,

Dieter Leibfritz1, 2

1University of Bremen, FB 2 (Chemistry), Bremen, Germany; 2Center of Advanced Imaging (CAI), Bremen, Germany; 3Radiology (667), Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands

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                  1244.    Removal of Lipid Nuisance Signals in MRSI Using Spatial-Spectral Constraints

 

Diego Hernando1, Justin Haldar1, Bradley Sutton1, Zhi-Pei Liang1

1University of Illinois at Urbana-Champaign, Urbana, Illinois, USA

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                  1245.    Fat Suppression for 1H MRSI at 7T Using a Spectrally Selective Adiabatic Inversion Pulse

 

Priti Balchandani1, Daniel Spielman1

1Stanford University, Stanford, California, USA

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                  1246.    Simultaneous Acquisition of Short and Long Echo Time Spectra of the Mouse Brain Using

                              Proton Magnetic Resonance Spectroscopic Imaging at 11.75 T

 

Pierre Larvaron1, Yann Le Fur1, Sylviane Confort-Gouny1, Patrick J Cozzone1, Angèle Viola1

1Centre de Résonance Magnétique Biologique et Médicale, UMR CNRS 6612, Marseille, France

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                  1247.    Short-TE Proton Spectroscopic Imaging of the Neurochemical Profile in the Rat Brain at 1 μl Resolution

 

Vladimir Mlynarik1, Giulio Gambarota1, Ingrid Kohler1, Rolf Gruetter1, 2

1Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; 2Universities of Lausanne and Geneva, Switzerland

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                  1248.    High-Resolution LASER-Localized Chemical Shift Imaging in the Rat Brain at 9.4 T

 

Julien Valette1, Christopher Nelson1, Isabelle Iltis1, Kamil Ugurbil1, Pierre-Gilles Henry1

1Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA

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                  1249.    Chemical Shift Independent Imaging of  19F Contrast Agents Using Ultrafast MRSI (F-uTSI)

 

Muhammed Yildirim1, 2, Jochen Keupp3, Klaas Nicolay2, Rolf Lamerichs1

1Philips Research, Eindhoven, Netherlands; 2Eindhoven University of Technology, Eindhoven, Netherlands; 3Philips Research, Hamburg, Germany

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                  1250.    Fast Spatial-Spectral Imaging of Hyperpolarized 13C Compounds Using Partial-Fourier

                              Multiple Echo 3DFIESTA

 

William H. Perman, Ph.D. 1, Pratip Bhattacharya2, 3, Alex Lin2, Jan Hovener, 24, Kent Harris2, Eduard Chekmenev2, Valerie A. Norton3, Daniel P. Weitekamp3, Brian D. Ross2

1Saint Louis University School of Medicine, St. Louis, Missouri, USA; 2Huntington Medical Research Institutes, Pasadena, California, USA; 3California Institute of Technology, Pasadena, California, USA; 4German Cancer Research Institute (DKFZ), Heidelberg, Germany

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                  1251.    Combination of Proton MRSI of the Brain Acquired Using a Multichannel Coil Without Water Suppression

 

Zhengchao Dong1, 2, Bradley Peterson1, 2

1Columbia University, New York, New York, USA; 2New York State Psychiatric Institute, New York, New York, USA

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                  1252.    Fast Chemical Shift Imaging with Ultra Short Echo Time

 

Yingli Yang1, Qi Zhao1, Srirama V. Swaminathan, 12, Stefan Fischer2, Truman R. Brown1

1Columbia University, New York, New York, USA; 2Philips Medical Systems, Cleveland, Ohio, USA

 

 

Elastography

Hall 14.1                     Monday 14:00 - 16:00

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                  1253.    Comparison of Spin Echo and Balanced Steady State Free Precession in MR-Elastography -

                              A First Step to Cardiac MR-Elastography

 

Benjamin Robert1, Ralph Sinkus1, Mickael Tanter1, Mathias Fink1

1Laboratoire Ondes et Acoustique, Paris, France

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                  1254.    In Vivo and In Vitro 7T MR Elastography with Parallel Imaging

 

Stefan Maderwald1, 2, Oliver Kraff, 12, Armin de Greiff, 12, Michael O. Zenge, 12, Frank Stock2, Titus Lanz3, Mark E. Ladd, 12

1University Duisburg-Essen, Essen, Germany; 2University Hospital Essen, Essen, Germany; 3RAPID Biomedical GmbH, Würzburg, Germany

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                  1255.    High Resolution MR-Elastography of In-Vivo Rat Brain – Understanding the

                              Scaling Behaviour of the Structures

 

Benoit Larrat1, Ralph Sinkus1, Mickael Tanter1, Mathias Fink1

1Laboratoire Ondes et Acoustique, Paris, France

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                  1256.    Direction Dependent Overestimation of Local Wavelengths in MR Elastography by Discretized

                              Helmholtz Inversion

 

Uwe Hamhaber1, Sebastian Papazoglou2, Ingolf Sack2, Dieter Klatt2, Jens Rump2, Jürgen Braun1

1Charité -Universitätsmedizin Berlin, Berlin, Germany; 2Charité - Universitätsmedizin Berlin, Berlin, Germany

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                  1257.    Vibration Safety Limits for Magnetic Resonance Elastography

 

Eric Ehman1, Phillip Rossman, Scott Kruse2

1Mayo Clinic, Rochester, Minnesota, USA; 2Mayo Clinic, Minnesota

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                  1258.    Position Dependent Shear Wave Group Velocities in In Vivo Human Biceps Muscle

 

Sebastian Papazoglou1, Uwe Hamhaber2, Jens Rump1, Dieter Klatt1, Jürgen Braun2, Ingolf Sack1

1Charité Berlin, Berlin, Germany; 2Charité, Berlin, Berlin, Germany

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                  1259.    Assessing the Mass Effect of Tumors on Adjacent Tissue: Initial Feasibility Study in a Phantom Model

 

Kevin Glaser1, Jose Pulido1, Richard Ehman1

1Mayo Clinic, Rochester, Minnesota, USA

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                  1260.    Reproducibility of Shear Modulus Estimates in Clinical Steady State MR Elastography

 

John Weaver1, Timothy Miller2, Phillip Perrinez2, Marvin Doyley2, Huifang Wang2, Yvonne Cheung1, Francis Kennedy2, Keith Paulsen2

1Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA; 2Dartmouth College, Hanover, New Hampshire, USA

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                  1261.    A Preliminary MR Elastography Database of In Vivo Human Brain Viscoelasticity

 

Bernd Beierbach1, Jens Würfel1, Jens Rump1, Sebastian Papazoglou1, Dieter Klatt1, Uwe Hamhaber1, Jürgen Braun1, Ingolf Sack1

1Charité - Universitätsmedizin Berlin, Berlin, Germany

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                  1262.    MR Elastography of the Eye: Initial Feasibility

 

Daniel V. Litwiller1, Jose S. Pulido2, Scott A. Kruse2, Kevin J. Glaser2, Richard L. Ehman2

1Mayo Clinic College of Medicine, Rochester, Minnesota, USA; 2Mayo Clinic, Rochester, Minnesota, USA

 

 

Hyperpolarized Noble Gas Imaging

Hall 14.1                     Monday 14:00 - 16:00

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                  1263.    129Xe Polarizer Commercial Prototype

 

Stephen Ketel1, Jeffrey Ketel2, Jan Distelbrink2, Walt Porter2, Korac MacArthur1, John Brackett2, Dianna Muth1, Aaron Hope2, F William Hersman1, 2

1University of New Hampshire, Durham, New Hampshire, USA; 2Xemed LLC., Durham, New Hampshire, USA

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                  1264.    Automated Hyperpolarized 129Xe Gas Generator for Biomedical MRI/MRS Applications

 

Mineyuki Hattori1, Tomokazu Numano1, Kazuhiro Homma1, Takashi Hiraga2, Morio Murayama3, Norio Ohtake3

1National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan; 2National Institute of Advanced Industrial Science and Technology, Ikeda, Osaka, Japan; 3Toyoko Kagaku Co. Ltd., Kawasaki, Kanagawa, Japan

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                  1265.    Scaling Up 129Xe Hyperpolarization - A Diagnostic Tools System

 

Isabel Maria Anna Dregely1, Iulian C. Ruset1, Edward J. Kotkowski1, F. William Hersman1

1University of New Hampshire, Durham, New Hampshire, USA

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                  1266.    Scaling-Up 129Xe Hyperpolarization - Theoretical Modeling

 

Iulian C. Ruset1, 2, F. W. Hersman1, 2, Robert Carrier1, Silviu Doru Covrig1, Adrian Sindile1, Jan Distelbrink2

1University of New Hampshire, Durham, New Hampshire, USA; 2XEMED, Durham, New Hampshire, USA

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                  1267.    An Economical Laboratory-Scale System for Purifying 3He

 

Robert Cadman1, Stephen Kadlecek1, James Baumgardner2, Chris Cox1, John MacDuffie Woodburn1, Sheeva Rajaei1, Vahid Vahdat1, Kiarash Emami1, Jiangsheng Yu1, Masaru C. Ishii3, Rahim Rizi1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Oscillogy LLC, Folsom, Pennsylvania, USA; 3Johns Hopkins University, Baltimore, Maryland, USA

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                  1268.    A Robust Transmitter Calibration Procedure for NMR of Hyperpolarized Nuclei

 

G Wilson Miller1, Michael Carl2, Eduard E. de Lange1, Talissa A. Altes1, Gordon D. Cates, 12, William Alexander Tobias2, John P. Mugler III1

1University of Virginia School of Medicine, Charlottesville, Virginia, USA; 2University of Virginia, Charlottesville, Virginia, USA

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                  1269.    Direct Molecular Solution of Hyperpolarized 129Xe Through Hollow Fiber Membranes

 

Jörg Schmiedeskamp1, Paul Philipp Zänker1, Rodolfo Hector Acosta2, Luis Agulles Pedros1, Peter Blümler3, Horst Dieter Lemke4, Florian M. Meise5, Wolfgang G. Schreiber5, Hans Wolfgang Spiess1

1Max Planck Institute for Polymer Research, Mainz, Germany; 2             Universidad Nacional de Cordoba, Cordoba, Argentina; 3Research Centre Jülich, Jülich, Germany; 4Membrana GmbH, Obernburg, Germany; 5Mainz University Medical School, Mainz, Germany

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                  1270.    Optimum Ventilation Mixture Ratio for Maximizing Hyperpolarized 129Xe MR Brain Signal

 

Xin Zhou1, Yang-Sheng Tzeng1, 2, Joey K. Mansour1, Mary L. Mazzanti1, Yanping Sun1, Mitchell S. Albert1

1Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; 2Boston University, Boston, Massachusetts, USA

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                  1271.    Comparison of 129Xe Pulmonary Gas Exchange Measured by Two Techniques: XTC and CSSR

 

Iga Muradian1, 2, Mirko Hrovat3, James Butler4, Christina Johnson1, 2, F. William Hersman1, Samuel Patz2

1University of New Hampshire, Durham, New Hampshire, USA; 2Brigham and Women's Hospital, Boston, Massachusetts, USA; 3Mirtech, Inc., Brockton, Massachusetts, USA; 4Harvard School of Public Health, Boston, Massachusetts, USA

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                  1272.    Detecting Emphysematous Lung in a Rabbit Model Using XTC MRI

 

Kai Ruppert1, Jaime F. Mata2, Jing Cai2, Talissa A. Altes3, Hsuan-Tsung J. Wang2, William A. Tobias2, Gordon D. Cates2, James R. Brookeman2, Klaus D. Hagspiel2, John P. Mugler III2

1The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; 2University of Virginia, Virginia, USA; 3The Children's Hospital of Philadelphia, Pennsylvania, USA

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                  1273.    Development of Novel Parameter That Reflects Xe Transfer Rate in Mouse Lung from

                              Hyperpolarized 129Xe Dynamic Study Under Spontaneous Respiration: Definition and Application

                              to Murine Tumor B16BL6 Melanoma

 

Hirohiko Imai1, Tsuyoshi Ito1, Atsuomi Kimura1, Shinsaku Nakagawa1, Hideaki Fujiwara1

1Osaka University, Suita, Osaka 565-0871, Japan

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                  1274.    Hyperpolarized Xe-129 as a Non-Invasive Biosensor to Characterize Atherosclerotic Plaques

 

Zhaohui Han1, Nicholas N. Kuzma1

1University of Rochester, Rochester, New York, USA

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                  1275.    Imaging Stroke with Hyperpolarized 129Xe MRI

 

Xin Zhou1, Yanping Sun1, Mary L. Mazzanti1, Nils Henninger2, Jessica D. Gereige1, Joey K. Mansour1, Marc Fisher2, Mitchell S. Albert1

1Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; 2University of Massachusetts Medical School, Worcester, Massachusetts, USA

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                  1276.    Phase Contrast Imaging of Flow Dynamics in the Lungs Using Hyperpolarized Helium

 

Vinay Manjunath Pai1, Igor Kamenetskiy1, Davide Santoro1, Jean Reid1, Glyn Johnson1

1New York University School of Medicine, New York, New York, USA

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                  1277.    Hyperpolarized Helium3 Phase-Contrast Velocimetry on Human Paranasal Sinus Ostial Patency

 

John M. Woodburn1, Masaru Ishii2, Jiangsheng Yu1, Kiarash Emami1, Chris Cox1, Stephen Kadlecek1, Vahid Vahdat1, Robert Cadman1, Sheeva Rajaei1, Takeshi Nakayama1, Richard Guyer1, David A. Lipson1, Warren Gefter1, Rahim Rizi1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Johns Hopkins University, Baltimore, Maryland, USA

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                  1278.    Validation of Phase-Contras MR Velocimetry of Hyperpolarized Rare Gases Via Particle Image Velocimetry

 

Wolfgang Kilian1, Tomasz Lindel1, M. Strowig1, André Brunn2, Frank Seifert1

1Physikalisch-Technische Bundesanstalt, Berlin, Germany; 2TU-Berlin, Berlin, Germany

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                  1279.    Voxel-Based Measurment of Flow and Volume Using Regional Motion-Tracking in the

                              Lung with Hyperpolarized 3He MRI

 

Davide Santoro1, Abram Voorhees2, Vinay Pai1, Igor Kamenetskiy1, Jean Reid1, Glyn Johnson1

1New York University, New York, New York, USA; 2Siemens Medical Solutions, Malvern, Pennsylvania, USA

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                  1280.    Hyperpolarized Helium-3 Spiral Ventilation Imaging: Implementation and Validation of a

                              Free-Breathing Protocol on a Clinical MR Scanner

 

Elise Bannier1, Katarzyna Cieslar2, Vasile Stupar1, Robin M. Heidemann3, Sophie Gaillard1, Abdulrazzaq Sulaiman1, Emmanuelle Canet-Soulas1, Yannick Cremillieux1

1CNRS, UMR 5012, Laboratoire RMN-MIB, ESCPE, Villeurbanne, France; 2Jagiellonian University, Kraków, Poland; 3Siemens Medical Solutions, Erlangen, Germany

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                  1281.    Assessment of In-Vitro Lung Structure Using Hyperpolarized He-3 ADC MRI:

                              Comparison with In-Vivo Measurements and Repeatability

 

Jaime Mata1, Talissa Altes2, Kai Ruppert2, Klaus Hagspiel1, James Brookeman1, John Mugler III1

1University of Virginia, Charlottesville, Virginia, USA; 2University of Pennsylvania, Philadelphia, Pennsylvania, USA

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                  1282.    New Sequence for a Fast and Accurate Measurement of Hyperpolarized Helium-3 Diffusion

 

Dayane Habib1, Geneviève Guillot1

1Université Paris-Sud, Orsay, France

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                  1283.    Probing Lung Geometry: Measurement of Time-Dependent Diffusion of Hyperpolarized

                                       129Xe in Healthy Mice

 

Tetsuya Wakayama1, Masakazu Kitamoto1, Atsuomi Kimura1, Hideaki Fujiwaka1

1Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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                  1284.    Measurement of the Diffusion of Hyperpolarized 3He in Human Lungs Over Short and

                              Long Time Scales During One Breath Hold

 

Chengbo Wang1, Grady W. Miller1, Tallisa A. Altes1, 2, Eduard E. de Lange1, James R. Brookeman1, Gordon D. Cates, Jr1, John P. Mugler, III1

1University of Virginia, Charlottesville, Virginia, USA; 2Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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                  1285.    Measurement of Hyperpolarized Gas Diffusion at Very Short Time Scales

 

Michael Carl1, Grady Wilson Miller1, John P. Mugler III1, Scott Rohrbaugh1, William Al Tobias1, Gordon D. Cates1

1University of Virginia, Charlottesville, Virginia, USA

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                  1286.    SNR Performance of Q-Space Formalism and Multi-Exponential Modelling for Hyperpolarized

                                       3He Gas Diffusion Spectroscopy in Human Lungs

 

Dattesh D. Shanbhag1, 2, Talissa A. Altes3, Jaime F. Mata1, G.Wilson Miller1, Jack Knight-Scott4

1University of Virginia, Charlottesville, Virginia, USA; 2GE JFWTC, Bangalore, Karnataka, India; 3The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; 4Children's Healthcare of Atlanta at Egleston, Atlanta, Georgia, USA

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                  1287.    A Rapid Hyperpolarized 3He Q-Space Diffusion Spectroscopy Sequence for Sub-Second

                             Breath Hold In Vivo

 

Dattesh D. Shanbhag1, 2, Talissa A. Altes3, Jaime F. Mata1, G.Wilson Miller1, Jack Knight-Scott4

1University of Virginia, Charlottesville, Virginia, USA; 2GE JFWTC, Bangalore, Karnataka, India; 3The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; 4Children's Healthcare of Atlanta at Egleston, Atlanta, Georgia, USA

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                  1288.    Finite Element Modeling and Experimental Validation of Transverse Relaxation and

                              Apparent Diffusion Coefficients of Hyperpolarized Noble Gases in Rodent Lung

 

Juan Parra-Robles1, Peggy Xu2, Wilfred Lam1, Alexei Ouriadov1, David McCormack2, Giles E. Santyr1

1Robarts Research Institute, London, Ontario, Canada; 2University of Western Ontario, London, Ontario, Canada

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                  1289.    Measurements of Hyperpolarized He-3 T2* and ADC in the Lungs Using Multi-Echo VIPR

 

James Holmes1, Rafael O'Halloran1, Ethan Brodsky1, Walter Block1, Sean Fain1

1University of Wisconsin-Madison, Madison, Wisconsin, USA

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                  1290.    Human Pulmonary Diffusion Weighted Imaging at 0.2T with Hyperpolarized 129Xe

 

Adrian Sindile1, Iga Muradian1, 2, Mirko Hrovat3, Christina Johnson1, 2, F. William Hersman1, Samuel Patz2

1University of New Hampshire, Durham, New Hampshire, USA; 2Brigham and Women's Hospital, Boston, Massachusetts, USA; 3Mirtech, Inc., Brockton, Massachusetts, USA

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                  1291.    Progression of Emphysema Evaluated by Hyperpolarized 3He ADC Measurements

 

Lise Vejby Søgaard1, Trine Stavngaard1, Marion Batz2, Wolfgang G. Schreiber3, Asger Dirksen4

1Copenhagen University Hospital, Hvidovre, Denmark; 2Johannes Gutenberg-University, Mainz, Germany; 3Johannes Gutenberg-University Medical School, Mainz, Germany; 4Gentofte University Hospital, Hellerup, Denmark

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                  1292.    Evaluation of Radiation Lung Injury from Tomotherapy Using Hyperpolarized Helium-3 Diffusion MRI

 

Jaime Mata1, Jing Cai1, Ke Sheng1, Kai Ruppert2, 3, Paul Read1, Klaus Hagspiel1, Talissa Altes2, 4, James Brookeman1, John Mugler III1

1University of Virginia, Charlottesville, Virginia, USA; 2University of Pennsylvania, Philadelphia, Pennsylvania, USA; 3Children's Hospital of Philadelphia, Philadelphia, Virginia, USA; 4Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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                  1293.    Hyperpolarized 3He MRI at 3.0 Telsa: Anatomic Bias of Apparent Diffusion Coefficients in

                              Chronic Obstructive Pulmonary Disease

 

Andrea Evans1, 2, David McCormack2, Shayna McKay1, Roya Etemad-Rezai2, Giles Santyr1, 2, Grace Parraga1, 2

1Robarts Research Institute, London, Ontario, Canada; 2The University of Western Ontario, London, Ontario, Canada

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                  1294.    Ventilation and Perfusion Ratio Obtained by Polarized Carbon-13 and Polarized Gas MRI

 

Masaru Ishii1, Jiangsheng Yu2, Stephen Kadlecek2, Kiarash Emami2, John M. Woodburn2, Vahid Vahdat2, Takeshi Nakayama2, Robert Cadman2, Sheeva Rajaei2, Chris Cox2, Richard Guyer2, Michelle Law2, Michael Stephen3, David A. Lipson2, Warren Gefter2, Rahim Rizi2

1Johns Hopkins University, Baltimore, Maryland, USA; 2University of Pennsylvania, Philadelphia, Pennsylvania, USA; 3University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

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                  1295.    Optimization of Steady State Free Precession Sequences for Hyperpolarized 3He Lung MRI

 

Jim M. Wild1, Kevin Teh1, Neil Woodhouse1, Martyn NJ Paley1, Nicola de Zanche2, Larry Kasuboski3

1University of Sheffield, Sheffield, Yorkshire, UK; 2ETH, Zurich, Switzerland; 3Philips Medical Systems, Ohio

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                  1296.    Multiple Regression Method for Optimizing Scan Parameters in Pulmonary Partial Pressure

                             Oxygen Measurement by Hyperpolarized 3He MRI

 

Jiangsheng Yu1, David Lipson1, Masaru C. Ishii2, Stephen Kadlecek1, Kiarash Emami1, Vahid Vahdat1, John MacDuffie Woodburn1, Robert Cadman1, Sheeva Rajaei1, Warren Gefter1, Rahim Rizi1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Johns Hopkins University, Baltimore, Maryland, USA

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                  1297.    Slice Profile Effects in Variable Flip Angle Hyperpolarized 3He MRI

 

Kevin Teh1, Kuan J. Lee1, Jim M. Wild1

1University of Sheffield, Sheffield, Yorkshire, UK

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                  1298.    Automated Algorithm for Calculation of Lung Defect Volume Using Hyperpolarized He-3 MRI

                             and Proton Magnetic Resonance Imaging

 

Guillermo Gonzalez-Fernandez1, Eric Peterson1, Rafael O'Halloran1, Sean Fain1

1University of Wisconsin-Madison, Madison, Wisconsin, USA

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                  1299.    Airway Segmentation in 3D Using Dynamic Hyperpolarized He-3 Multi-Echo VIPR

 

Eric Peterson1, Jim Holmes1, Guillermo Gonzalez-Fernandez1, Rafael O'Halloran1, Ethan Brodsky1, Wally Block1, Sean Fain1

1University of Wisconsin - Madison, Madison, Wisconsin, USA

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                  1300.    Reproducibility of Partial Pressure of Oxygen and Oxygen Depletion Rate in Animal Model

 

Masaru Ishii1, Jiangsheng Yu2, Stephen Kadlecek2, Kiarash Emami2, John M. Woodburn2, Vahid Vahdat2, Takeshi Nakayama2, Robert Cadman2, Sheeva Rajaei2, Chris Cox2, Richard Guyer2, Michelle Law2, Michael Stephen3, David A. Lipson2, Warren Gefter2, Rahim Rizi2

1Johns Hopkins University, Baltimore, Maryland, USA; 2University of Pennsylvania, Philadelphia, Pennsylvania, USA; 3University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

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                  1301.    Longitudinal Helium-3 and Proton Imaging of Magnetite Biodistribution in a Rat Model of

                              Instilled Nanoparticles

 

Achraf Al Faraj1, Ghislaine Lacroix2, hasan Al Said1, Dan Elgrabi2, Vasile Stupar1, Franck Robidel2, Sophie Gaillard1, Emmanuelle Canet-Soulas1, Yannick Crémillieux1

1Université Lyon 1, Villeurbanne, France; 2INERIS, Verneuil-en-Halatte, France

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                  1302.    Quantitative Analysis of MCh Induced Ventilation Changes in Mouse Lungs

 

Nilesh Navnitlal Mistry1, 2, Bastiaan Driehuys2, G. Allan Johnson2

1Duke University, Durham, North Carolina, USA; 2Duke University Medical Center, Durham, North Carolina, USA

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                  1303.    Assessment of Lung Volumes Using Hyperpolarized 3He MR Imaging in Rodents: Comparison

                              with Xenon-Enhanced X-Ray CT

 

M Reza Akhavan Sharif1, 2, Wilfred W. Lam1, Alexei V. Ouriadov1, David W. Holdsworth1, 2, David G. McCormack3, Giles E. Santyr1, 2

1Robarts Research Institute, London, Ontario, Canada; 2University of Western Ontario, London, Ontario, Canada; 3London Health Sciences Centre, London, Ontario, Canada

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                  1304.    Hyperpolarized 3He Magnetic Resonance Imaging of Ventilation Defect Volume Variability in COPD

 

Lindsay Mathew1, 2, Jade Fenster1, Shayna McKay1, Giles Santyr1, 2, Roya Etemad-Rezai2, David McCormack2, Grace Parraga1, 2

1Robarts Research Institute, London, Ontario, Canada; 2The University of Western Ontario, London, Ontario, Canada

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                  1305.    Evaluation of the Safety of Hyperpolarized Helium-3 Gas as an Inhaled Contrast Agent for MRI

 

Talissa A. Altes1, 2, Joanne C. Gersbach1, Jaime F. Mata1, John P. Mugler III1, James R. Brookeman1, Eduard E. de Lange1

1University of Virginia, Charlottesville, Virginia, USA; 2Children's Hiaospital of Philadelph, Philadelphia, Pennsylvania, USA

 

 

Hyperpolarization:  C-13 and Other Nuclei

Hall 14.1                     Monday 14:00 - 16:00

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                  1306.    A Shielded NMR System Suitable for Parahydrogen-Induced Polarization

 

Takeshi Nakayama1, Kiarash Emami1, Stephen Kadlecek1, Stephen Pickup1, John M. Woodburn1, Jianliang Zhu1, Jiangsheng Yu1, Vahid Vahdat1, Masaru Ishii2, Robert Cadman1, Sheeva Rajaei1, Chris Cox1, Richard Guyer1, Michelle Law1, Michael Stephen3, Joseph Shrager1, David A. Lipson1, Warren Gefter1, Rahim Rizi1, sheeva rajaei4

1University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Johns Hopkins University, Baltimore, Maryland, USA; 3University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA; 4university of pennsylvania, philadelphia, Pennsylvania, USA

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                  1307.    Precise Flip Angle Calibration for Hyperpolarized 13C Scans

 

Ileana Hancu1, Ronald Watkins1, Susan Kohler2, Richard Mallozzi1

1GE Global Research Center, Niskayuna, New York, USA; 2GE Healthcare, Niskayuna, New York, USA

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                  1308.    Selective Homonuclear Hartmann-Hahn for 13C-13C Polarization Transfer in Solution State NMR

 

Thomas Roger Eykyn1, Martin O. Leach1

1Institute of Cancer Research, Sutton, Surrey, UK

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                  1309.    How Low Can We Go?  Limits of Detection in PASADENA 13C Hyperpolarization

 

Pratip Bhattacharya1, 2, Kent Christopher Harris1, 2, Eduard Y. Chekmenev, 23, Alexander Peter Lin1, 2, Valerie Ann Norton2, Jan Hovener, 23, William H. Perman4, Brian David Ross1, Daniel P. Weitekamp2

1Huntington Medical Research Institute, Pasadena, California, USA; 2California Institute of Technology, Pasadena, California, USA; 3Rudi Schulte Research Institute, Santa Barbara, California, USA; 4St. Louis University School of Medicine, Saint Louis, Michigan, USA

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                  1310.    Off-Resonance Behaviour of RARE and TrueFISP in Imaging of Hyperpolarized 13C

 

Jochen Leupold1, Sven Månsson2, Oliver Wieben3, Klaus Scheffler4, Jürgen Hennig1

1University Hospital Freiburg, Freiburg, Germany; 2GE Healthcare, Malmö, Sweden; 3University of Wisconsin-Madison, Madison, Wisconsin, USA; 4University Hospital of Basel, Basel, Switzerland

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                  1311.    Reproducibility and Quality Assurance in Hyperpolarized 13C MRI and MRS

 

Jan B. Hövener1, 2, Pratip Bhattacharya1, 2, Eduard Y. Chekmenev1, 2, Valerie Norton2, William H. Perman3, Alexander Lin1, Kent Harris1, Daniel P. Weitekamp2, Brian D. Ross1

1Huntington Medical Research Institute, Pasadena, California, USA; 2California Institute of Technology, Pasadena, California, USA; 3St. Louis University, School of Medicine, St. Louis, Michigan, USA

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                  1312.    Generating 1H- And 13C-Hyperpolarized Molecular Probes of Variable Size from Parahydrogen to

                              Explore the Lung Via MRI

 

Joachim Bargon1, Matthias Stephan2, Rahim Rizi3

1University of Bonn, Bonn, Germany; 2University of Bonn, Germany; 3University of Pennsylvania, Philadelphia, Pennsylvania, USA

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                  1313.    PASADENA: A Novel Tool to Image Atherosclerotic Plaque

 

Eduard Y. Chekmenev1, 2, Pratip Bhattacharya1, 2, Siu K. Chow3, Alexander P. Lin1, 4, Daniel P. Weitekamp2, Brian D. Ross1, 4

1Huntington Medical Research Institutes, Pasadena, California, USA; 2California Institute of Technology, Pasadena, California, USA; 3UCSD, San Diego, California, USA; 4Rudi Schulte Research Institutes, Santa Barbara, California, USA

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                  1314.    Kinetic Data from Cellular Assay Using Hyperpolarized 13C-DNP-NMR

 

Magnus Karlsson1, Linda Andersson1, Pernille Jensen1, Georg Hansson1, Anna Gisselsson1, Sven Månsson1, Rene in 't Zandt1, Mathilde Lerche1

1Imagnia AB, Malmö, Sweden

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                  1315.    Freely Diffusible Contrast Agents for Hyperpolarized 13C Perfusion Imaging

 

Aaron K. Grant1, Elena Vinogradov1, David Alsop1

1Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

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                  1316.    Parahydrogen Induced Polarization of Drug Compounds for MRI

 

Achim Koch1, Jörg Schmiedeskamp1, Joachim Bargon2, Hans Wolfgang Spiess1

1Max Planck Institute for Polymer Research, Mainz, Germany; 2University of Bonn, Bonn, Germany

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                  1317.    Parahydrogen-Induced Hyperpolarization of 15N

 

Joachim Bargon1, Achim Koch2, Johannes Natterer3, Rahim Rizi4, Jorg Schmiedeskamp2

1University of Bonn, Bonn, Germany; 2Max Planck Institute for Polymer Research                , Mainz, Germany; 3University of Bonn, Germany; 4University of Pennsylvania, Philadelphia, Pennsylvania, USA

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                  1318.    Towards Detection of Sub-Micromolar Contrast Agent Concentration with Hyperpolarized 6-Lithium

 

Ruud B. van Heeswijk1, Kai Uffmann1, Fiodar Kurdzesau2, 3, Sami Jannin3, Arnaud Comment3, Ton Konter2, Patrick Hautle2, Ben van den Brandt2, Jacques J. van der Klink3, Gil Navon4, Rolf Gruetter1, 5

1Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; 2Paul Scherrer Institute, Villigen, Switzerland; 3Ecole Polytechnique Fédérale de Lausanne, Lausanne, VD, Switzerland; 4Tel Aviv University, Tel-Aviv, Israel; 5Universities of Lausanne and Geneva, Switzerland

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                  1319.    Hyperpolarized N-15 of Choline - Potential for Observing Phospholipid Metabolism in Cancer

 

Thomas Roger Eykyn1, Steven Reynolds2, Cristina Gabellieri1, Martin O. Leach1

1Institute of Cancer Research, Sutton, Surrey, UK; 2Oxford Instruments Molecular Biotools Ltd., Tubney Woods, Abingdon, Oxon, UK

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                  1320.    Characterization of Solid State Dynamic Nuclear Polarization for Metabolic Imaging

 

Marie Allen Schroeder1, Lowri Elizabeth Cochlin1, George K. Radda1, Kieran Clarke1, Damian J. Tyler1

1University of Oxford, Oxford, Oxon, UK

 

 

EPR

Hall 14.1                     Monday 14:00 - 16:00

 

                  1321.    Development of Micro-Pellets Holding EPR Oxygen Sensors

Mustapha Dinguizli1, Bernard Gallez1

1Université catholique de Louvain, Brussels, B, Belgium
 

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                  1322.    High Resolution 2D and 3D EPR Imaging of Melanin in Biological Samples

 

Emilia Sabina Vanea1, Nicolas Charlier1, Mustapha Dinguizli1, Bernard Gallez1

1Université Catholique de Louvain, Brussels, B, Belgium

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                  1323.    Changes in Serum Albumin Measured by Electron Spin Resonance: In Vitro Diagnostic EPR Test

 

Andrey Gurachevsky1, Gert Matthes, 12, Vladimir Muravsky1

1MedInnovation GmbH, Wildau, Germany; 2University Hospital Leipzig, Germany

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                  1324.    Strategies for Improved Temporal and Spatial Resolution: In Vivo Oxymetric Imaging Using

                              Time-Domain EPR

 

Nallathamby Devasahayam1, Sankaran Subramanian1, Ramachandran Murugesan2, Fuminori Hyodo1, Ken-Ichiro Matsumoto3, James B. Mitchell1, Murali C. Krishna1

1National Institutes of Health, Bethesda, Maryland, USA; 2Madurai Kamaraj University, Madurai, Tamil Nadu, India; 3National Institute of Radiological Science, Chiba-shi, Chiba 263-8555, Japan

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                  1325.    Evaluation of Radiation Dose Distribution in Lithium Formate Pellets Using EPR Imaging

 

Emilia Sabina Vanea1, Jean-Marc Denis2, Stefaan Vynckier2, Bernard Gallez1

1Université Catholique de Louvain, Brussels, Belgium; 2Université catholique de Louvain, Brussels, Belgium

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                  1326.    Sequential Imaging of Tissue pO2 by Electron Paramagnetic Resonance Imaging and Anatomy

                              by MRI at 300 MHz

 

Shingo Matsumoto1, Fuminori Hyodo1, Nallathamby Devasahayam1, Sankaran Subramanian1, Jeeva P. Munasinghe2, James B. Mitchell1, Murali C. Krishna1

1National Cancer Institute, NIH, Bethesda, Maryland, USA; 2National Institute of Neurological Disorder and Stroke, NIH, Bethesda, Maryland, USA

 

 

Non-Proton MRI

Hall 14.1                     Monday 14:00 - 16:00

 

                  1327.    High Resolution Sodium Imaging of Isolated Neurons

Samuel Colles Grant1, 2

1The National High Magnetic Field Laboratory, Tallahassee, Florida, USA; 2The Florida State University, Tallahassee, Florida, USA

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                  1328.    Sodium Chemical Shift Imaging of Induced Diuresis in a Mouse Renal Model

 

Thomas Neuberger1, 2, Vikas Gulani2, 3, Andrew Webb1, 2

1Huck Institute Magnetic Resonance Centre, Penn State University, University Park, Pennsylvania, USA; 2University of Würzburg, Würzburg, Germany; 3Case Western Reserve University, Cleveland, Ohio, USA

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                  1329.    In Vivo Sodium MRI Relaxometry of Normal and Pathological Mouse Liver at 4.7 T

 

Mihaela Lupu1, 2, Carole D. Thomas1, 2, Andreas Volk1, 2, Joel Mispelter1, 2

1Institut Curie, Orsay, France; 2INSERM U759, Orsay, France

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                  1330.    Performance Comparison of Direct Fourier Sum and Regridding Reconstructions of Sodium TPI

 

Serge Minin1, Ian Atkinson2, Fred Damen2, Farzad Kamalabadi1, Keith R. Thulborn2

1University of Illinois, Urbana, Illinois, USA; 2University of Illinois Medical Center, Chicago, Illinois, USA

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                  1331.    MR Imaging of Sodium Using a 3D Cones Acquisition

 

Jeff A. Stainsby1, Paul T. Gurney2, Belinda S. Li3, Fred C. Damen4, Keith R. Thulborn4

1GE Healthcare, Toronto, Ontario, Canada; 2Stanford University, California, USA; 3GE Healthcare, Chicago, Illinois, USA; 4University of Illinois at Chicago, Chicago, Illinois, USA

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                  1332.    Optimization of Acquisition and Post-Processing Strategies for Na-23 Imaging of the Human Kidney

 

Yael Rosen1, 2, Ananth Madhuranthakam3, Alexander Ivanishev1, Robert E. Lenkinski1, 2

1Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; 2Harvard Medical School, Boston, Massachusetts, USA; 3GE Healthcare, Boston, Massachusetts, USA

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                  1333.    Method for Electronically Setting Transmit Gain for Non-1H Imaging and Spectroscopy

 

Susan J. Kohler1, W Thomas Dixon1

1General Electric Company, Niskayuna, New York, USA

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                  1334.    Simultaneous 19F/1H Imaging for Quantification : Calibration and Sensitivity Assessment

 

Jochen Keupp1, Peter Caesar Mazurkewitz1

1Philips Research Europe, Hamburg, Germany

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                  1335.    Relationship Between 3He Gas ADCs and Lung Microstructure. Computer Simulations

 

Alexander L. Sukstanskii1, Mark S. Conradi1, Dmitriy A. Yablonskiy1

1Washington University, St. Louis, Missouri, USA

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                  1336.    Rapid In-Vivo MRI Measurement of Fluorinated Gas Concentration in Lungs Using T1- Mapping

 

Maxim V. Terekhov1, Ursula A. Wolf1, Alexander W. Scholz1, Wolfgang Guenther Schreiber1

1Mainz University Medical School, Mainz, Germany

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                  1337.    Variable Flip Angle MR Imaging of Regional Ventilation Using Hyperpolarized Helium in Rodent Lungs

 

Giles Santyr1, Wilfred Lam1, Alexei Ouriadov1, David McCormack2

1Robarts Research Institute, London, Ontario, Canada; 2London Health Sciences Centre, London, Ontario, Canada

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                  1338.    Dynamical 17O Imaging in Tumor Bearing Mice at 7T

 

Michiko Narazaki1, Yoko Kanazawa1, Sachiko Koike1, Koichi Ando1, Hiroo Ikehira1

1National Institute of Radiological Sciences, Chiba, Japan

 

 

New & Emerging Applications for MR Microscopy

Hall 14.1                     Monday 14:00 - 16:00

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                  1339.    Assessment of Cellular Growth in a Double Microbead Alginate Construct Via MR Microscopy

 

Parastou Foroutan1, 2, Nicholas Edward Simpson3, Jose A. Oca-Cossio3, Carol A. Sweeney3, Stephen John Blackband, 14, Samuel Colles Grant1, 2, Ioannis Constantinidis, 13

1The National High Magnetic Field Laboratory, Tallahassee, Florida, USA; 2The Florida State University, Tallahassee, Florida, USA; 3University of Florida, Gainesville, Florida, USA; 4The McKnight Brain Institute, Gainesville, Florida, USA

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                  1340.    High-Field MR Microscopy as a Tool for Comparative Morphological Studies: Soft Tissue

                              Discrimination in Sea Urchins

 

Alexander Ziegler1, Cornelius Faber2, Susanne Mueller3, Thomas Bartolomaeus1

1Freie Universität, Berlin, Germany; 2Universität Würzburg, Germany; 3Charité-Universitätsmedizin, Germany

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                  1341.    Experimental Investigation of One-Dimensional "DESIRE" for NMR Microscopy

 

Markus Weiger1, Yi Zeng1, Michael Fey1

1Bruker BioSpin AG, Faellanden, Switzerland

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                  1342.    MR Microscopy Can Resolve Differences in the Behaviour of Implantable Drug Delivery Biomaterials

 

Joshua M. Bray1, 2, Mark Filiaggi2, Steven D. Beyea1, 2

1National Research Council of Canada, Halifax, Nova Scotia, Canada; 2Dalhousie University, Halifax, Nova Scotia, Canada

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                  1343.    3D-MR-Based Polymer Gel Dosimetry of Proton Needle Beams

 

Andreas Georg Berg1, Christian Bayreder1, Jens Heufelder2, 3

1Medical University of Vienna, Vienna, Austria; 2Hahn-Meitner-Institut, Berlin, Germany; 3Paul Scherrer Institut, Switzerland

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                  1344.    Corresponding Non-Invasive 1H and 23Na MRI of Ancient Mummified Human Tissue

 

Kerstin Münnemann1, 2, Thomas Boeni3, Bernhard Blümich1, Giovanni Colacicco4, Frank Rühli3

1RWTH Aachen University, Aachen, Germany; 2Mainz University Medical School, Mainz, Germany; 3University of Zurich, Zürich, Switzerland; 4University of Zurich, Zurich, Switzerland

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                  1345.    Retrospective Gating for Whole Body Mouse MRI

 

Jonathan Bishop1, Lorinda Davidson1, Jun Dazai1, Mark Henkelman1, 2

1Hospital for Sick Children, Toronto, Ontario, Canada; 2University of Toronto, Toronto, Ontario, Canada

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                  1346.    Rapid MR Microscopy of the Mouse Inner Ear Structures in Vitro Using True-FISP at 7.0T

 

H. Douglas Morris1, Byung Yoon Choi1, Andrew J. Griffith1, John A. Butman1

1NIH, Bethesda, Maryland, USA

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                  1347.    In Vivo Magnetic Resonance Microimaging in Adult Zebrafish

 

Samira Kabli1, Herman Spaink1, Huub J. M. de Groot1, Alia Alia1

1Leiden University, Leiden, Netherlands

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                  1348.    Internal Motions of Manduca Sexta Pupae Studied Using Magnetic Resonance Microscopy

 

Kevin J. Hallock1

1Boston Medical Center, Boston, Massachusetts, USA

 

 

Spectroscopy Techniques

Hall 14.1                     Monday 14:00 - 16:00

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                  1349.    In Vivo Single Voxel 1H MR Spectroscopy with Segmented 2D-Selective RF Excitations

 

Wolfgang Weber-Fahr1, 2, Jürgen Finsterbusch1, 2

1University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2Neuroimage Nord, Hamburg-Kiel-Lübeck, Germany

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                  1350.    Spatial Localization with Pulsed Second-Order Shims

 

Robin A. de Graaf1, Douglas L. Rothman1, Terence W. Nixon1

1MRRC, Yale University, New Haven, Connecticut, USA

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                  1351.    Full Signal Intensity for Short Echo Time Localized Spectroscopy on a Clinical Scanner

 

Ralf Mekle1, 2, Vladimir Mlynarik1, Giulio Gambarota1, Rolf Gruetter1, 3

1Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland; 2University of Lausanne, Lausanne, Switzerland; 3Universities of Lausanne and Geneva, Lausanne/Geneva, Switzerland

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                  1352.    Short Echo Time Proton Spectroscopy of the Human Brain at 3 Tesla Using an Optimized

                              PRESS Sequence Without Water Suppression

 

Wolfgang Dreher1, 2, Christian Schuster1, 2, Dieter Leibfritz1, 2

1University of Bremen, FB 2 (Chemistry), Bremen, Germany; 2Center of Advanced Imaging (CAI), Bremen, Germany

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                  1353.    Extension of 8 Step Phase Cycling Scheme for Improved Lipid Suppression Using Four-Pulse

                              PRESS MRS Sequences

 

Shiloh Sison1, Michael H. Buonocore1, Richard J. Maddock1

1UC Davis Imaging Research Center, Sacramento, California, USA

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                  1354.    High-Resolution MRS in Inhomogeneous Fields Via Double-Quantum-Filtered Intermolecular

                             Zero-Quantum Coherences

 

Xi Chen1, Meijin Lin1, Zhong Chen1, 2, Jianhui Zhong2

1Xiamen University, Xiamen, Fujian, People’s Republic of China; 2University of Rochester Medical Center, Rochester, New York, USA

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                  1355.    Proton Spectroscopy Without Water Suppression Using a High Dynamic Range A/D Converter

 

Andrzej Jesmanowicz1, Robert Prost1, James S. Hyde1

1Medical College of Wisconsin, Milwaukee, Wisconsin, USA

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                  1356.    Robust Water and Lipid Suppression Using Multiple Dualband Frequency-Selective

                              RF Pulses for 1H Spectroscopic Imaging at 3T

 

Meng Gu1, Daniel Mark Spielman1

1Stanford University, Stanford, California, USA

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                  1357.    Single Voxel Spectroscopy of the Pons: Shimming, Quantitation, and Reproducibility Issues at 3T

 

Sergey Cheshkov1, Audrey Chang1, Subhendra Sarkar1, Evelyn Babcock1, Kaundinya Gopinath1, Richard Briggs1

1University of Texas Southwestern Medical Center, Dallas, Texas, USA

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                  1358.    Optimization of PRESS-Localized Metabolite Measurements in the Frontal Lobes In Vivo at 3T

 

Mary McLean1, James Stone2, David Lythgoe2, Gareth Barker2, John Duncan1

1UCL Institute of Neurology, London, England, UK; 2Kings College London, London, England, UK

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                  1359.    Localized H1-MRS of the Human Frontal White Matter at 3 T: Metabolite Concentrations and

                              Relaxation Times

 

Nuran Tunc-Skarka1, Tim Wokrina1, Marco Ulrich1, Gabi Ende1

1Central Institute of Mental Health, Mannheim, Germany

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                  1360.    Negligible Dehydroascorbate and GSSG Signal Contributions to Human Brain 1H NMR Spectra In Vivo

 

Melissa Terpstra1, Marjanska Malgorzata1, Pierre-Gilles Henry1, Ivan Tkac1

1University of Minnesota, Minneapolis, Minnesota, USA

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                  1361.    Quantitative Time-Domain Analysis of Intermolecular Multiple-Quantum Coherences (iMQC)

                              and Effects of Radiation Damping

 

Stefan Kirsch1, William Edmund Hull1

1German Cancer Research Center (DKFZ), Heidelberg, Germany

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                  1362.    Accurate Measurements of Small J Coupling Constants in Inhomogeneous Fields

 

Yanqin Lin1, Congbo Cai1, Shuhui Cai1, Zhong Chen1, 2, Jianhui Zhong2

1Xiamen University, Xiamen, Fujian, People’s Republic of China; 2University of Rochester Medical Center, Rochester, New York, USA

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                  1363.    Three-Dimensional, J-Resolved H-1 MRSI of Volunteers and Patients with Brain Tumors at 3 T

 

Yan Li1, Albert P. Chen1, Jason C. Crane1, Susan M. Chang1, Daniel B. Vigneron1, Sarah J. Nelson1

1University of California, San Francisco, California, USA

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                  1364.    Controlling J-Coupling Evolution During Selective RF Pulses

 

Lorenz Mitschang1

1Physikalisch-Technische Bundesanstalt, Berlin, Germany

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                  1365.    2D J-Resolved Spectroscopy at 7T

 

Duan Xu1, Yan Li1, 2, Albert P. Chen1, Ralph Hurd3, Jason Crane1, Sarah J. Nelson1, 2, Daniel B. Vigneron1, 2

1UCSF, San Francisco, California, USA; 2UCSF/UC Berkeley, San Francisco, Berkeley, California, USA; 3GE Healthcare, Menlo Park, California, USA

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                  1366.    Fast Acquisition of High-Resolution MRS in Inhomogeneous Fields Via Intermolecular

                              Single-Quantum Coherences

 

Zhong Chen1, 2, Xi Chen1, Shuhui Cai1, Jianhui Zhong2

1Xiamen University, Xiamen, Fujian, People’s Republic of China; 2University of Rochester Medical Center, Rochester, New York, USA

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                  1367.    Improved High-Resolution MRS in Inhomogeneous Fields Via Intermolecular Zero-Quantum Coherences

 

Shuhui Cai1, Song Chen1, Zhong Chen1, 2, Jianhui Zhong2

1Xiamen University, Xiamen, Fujian, People’s Republic of China; 2University of Rochester Medical Center, Rochester, New York, USA

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                  1368.    Prospects of Resolution and Senstivity Enhancement Using In Vivo iZQC MR Spectroscopy

 

David Zsolt Balla1, Cornelius Faber1

1University of Würzburg, Würzburg, Bavaria, Germany

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                  1369.    A Modified PRESS Sequence Designed for Lactate Editing

 

Atiyah Yahya1, B. Gino Fallone1

1Cross Cancer Institute, University of Alberta, Edmonton, Alberta, Canada

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                  1370.    Optimized Detection of Glutathione in the Human Brain at 3T Using MEGA-PRESS

 

Richard Anthony Edward Edden1, 2, Peter B. Barker1, 2

1The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 2Kennedy Krieger Institute, Baltimore, Maryland, USA

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                  1371.    Detection of Resolved Glutamate and/or Glutamine Using Optimized STEAM at 3T – a Verification

                             Study by Phantom Experiments

 

Shaolin Yang1, Jiani Hu2, Yihong Yang1

1National Institute on Drug Abuse, Baltimore, Maryland, USA; 2Wayne State University, Detroit, Michigan, USA

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                  1372.    In-Vivo Detection of Human Brain GABA* in Frontal Cortex, Thalamus and Hippocampus by

                             J-Difference Spectroscopy at 3T

 

Kevin Wayne Waddell1, James Michael Joers1, Eiman Shafa2, Parham Zhanjanipour1, Malcolm James Avison1, John C. Gore1

1Vanderbilt University, Nashville, Tennessee, USA; 2Temple University School of Medicine,

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                  1373.    In Vivo Measurements of Brain Serine with 1H-MRS

 

Jean Théberge1, 2, Perry F. Renshaw3

1St. Joseph's Health Care, London, Ontario, Canada; 2University of Western Ontario, London, Ontario, Canada; 3McLean Hospital, Belmont, Massachusetts, USA

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                  1374.    Simulation Study for Suppression of Myo-Inositol for Glycine Measurement by PRESS at

                              Various Field Strengths

 

Changho Choi1, Nicholas J. Coupland1, Paramjit P. Bhardwaj1, Sanjay Kalra1, Peter S. Allen1

1University of Alberta, Edmonton, Alberta, Canada

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                  1375.    Dynamics of Lactate Concentration and BOLD Effect Upon Repeated Identical Visual Stimuli

 

Silvia Mangia1, Ivan Tkac1, Nikos Logothetis2, Pierre-Francois Van de Moortele1, Rolf Gruetter3, Kamil Ugurbil1, 2

1University of Minnesota, Minneapolis, Minnesota, USA; 2Max Planck Institute for Biological Cybernetics, Tubingen, Germany; 3Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland

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                  1376.    T1 Measurement of Brain Metabolites at 3T with a Saturated-Inversion Recovery Method

 

Albert P. Chen1, Charles H. Cunningham2, Duan Xu1, Yan Li1, 3, Sarah J. Nelson1, 3, Daniel B. Vigneron1, 3

1UCSF, San Francisco, California, USA; 2University of Toronto, Toronto, Ontario, Canada; 3UCSF/UCB, San Francisco, California, USA

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                  1377.    Stand-Alone GUI of Analyzing and Displaying Proton 2D/3D MRSI Data Sets with LCModel

 

Meng-Hsueh Yu1, Cheng-Wen Ko1, Shang-Yueh Tsai2, Martin Buechert3, Ping-Hong Lai4

1National Sun Yat-sen University, Kaohsiung, Taiwan; 2National Taiwan University, Taipei, Taiwan; 3University Hospital Freiburg, Freiburg, Germany; 4Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan

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                  1378.    A New Post-Processing Method to Remove Ringing Artifacts in Clinical MR Spectra

 

Yuxi Pang1, Thomas L. Chenevert1, Marko Ivancevic2, Pia C. Sundgren1

1University of Michigan, Ann Arbor, Michigan, USA; 2Philips Medical Systems, Cleveland,

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                  1379.    13C Multi-Spectral 2D Rosette Imaging

 

Elizabeth Kathleen Bucholz1, Susan Kohler2, Ileana Hancu3

1Duke University, Durham, North Carolina, USA; 2GE, Niskayuna, New York, USA; 3GE, Niskyuna, New York, USA

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                  1380.    In Vivo Metabolite Compartmentalization Probed Using Intracellular GdDTPA

 

David Alberg Holm1, 2, Ian John Rowland1

1Hvidovre Hospital, Hvidovre, Denmark; 2Technical University of Denmark, Lyngby, Denmark

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                  1381.    1H MRS During Creatine Supplementation in GAMT Deficient Knockout Mice Elucidates an Early

                              Difference in Creatine Uptake Between Muscle and Brain

 

Hermien E. Kan1, Esther Meeuwissen1, Jack van Asten1, Andor Veltien1, Dirk Isbrandt2, Arend Heerschap1

1Radboud University Nijmegen Medical Center, Nijmegen, Netherlands; 2Center for Molecular Neurobiology Hamburg, Hamburg, Germany

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                  1382.    Effect of Ischemia on Muscle Metabolites Assessed with Functional Magnetic Resonance

                             Spectroscopy (fMRS) During Electrically Imposed Exercise

 

Johannes Slotboom1, Werner J. Z'Graggen1, Arto C. Nirkko1

1University Hospital, Bern, Switzerland

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                  1383.    Age Effect on Intramyocellular Lipid Composition in Db/db Mice Using In Vivo 1H-MR Spectroscopy

 

Rachida Fissoune1, Marc Janier2, André Briguet1, Bassem Hiba3

1Université Lyon1, Laboratoire de RMN CNRS UMR 5012, Lyon, France; 2Platform ANIMAGE, Rhone-Alpes Genopole, Lyon, France; 3Platform ANIMAGE, Rhone-Alpes Genopole, Lyon, France

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                  1384.    In Vivo Proton Magnetic Resonance Spectroscopy of Human Adipose Tissue Fatty Acids: A Feasibility Study

 

Jesper Lundbom1, Antti Hakkarainen1, Marja-Riitta Taskinen1, Nina Lundbom1

1Hospital District of Helsinki and Uusimaa, Helsinki, Finland

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                  1385.    RF Pulse Design for Adiabatic Spin Decoupling

 

Lorenz Mitschang1

1Physikalisch-Technische Bundesanstalt, Berlin, Germany

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                  1386.    Providing 1H- And 13C-Hyperpolarized Gamma-Aminobutyric Acid (GABA) for Parahydrogen-Enhanced

                              MRI and MRS

 

Joachim Bargon1, Achim Koch2, Rahim Rizi3, Jorg Schmiedeskamp2

1University of Bonn, Bonn, Germany; 2Max Planck Institute for Polymer Research                , Mainz, Germany; 3University of Pennsylvania, Philadelphia, Pennsylvania, USA

 

 

Spectroscopic Quantitation

Hall 14.1                     Monday 14:00 - 16:00

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                  1387.    Improved Tissue Metabolite Quantification in 1H HR-MAS Spectroscopy Using the ERETIC Method

 

Thomas Nordling Butler1, Mark Julius Albers1, 2, Kayvan Keshari1, Mark Gunnard Swanson1, 2, John Kurhanewicz1, 2

1University of California San Francisco, San Francisco, California, USA; 2UC Berkeley / UC San Francisco, San Francisco, California, USA

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                  1388.    (1)H-HRMAS for Quantitative Measurement of Choline Concentration in Amniotic Fluid as a Marker

                              of Fetal Lung Maturity:  Inter- And Intra-Observer Reproducibility Study

 

Bonnie N. Joe1, Mark G. Swanson1, Kiarash Vahidi1, Andrew Zektzer1, Mei-Hsiu Chen2, Matthew Clifton1, Thomas Butler1, Kayvan Keshari1, John Kurhanewicz1

1UCSF, San Francisco, California, USA; 2Brown University, Providence, Rhode Island, USA

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                  1389.    Quantitative Measurement of Neurotransmitters in Rat Brain Tissue Using HR MAS 13C NMR

                              Spectroscopy and the ERETIC Method

 

Øystein Risa1, Torun Margareta Melø1, Ursula Sonnewald1

1Norwegian University of Science and Technology (NTNU), Trondheim, Norway

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                  1390.    Measurement of Citrate Chemical Shift Changes in HR-MAS NMR Spectra of Prostate Biopsies

 

Paul Allen DiCamillo1, Mark Gunnard Swanson1, Zoe Laura Tabatabai, 12, John Kurhanewicz1, Sarah Jane Nelson1

1University of California, San Francisco, California, USA; 2VA Medical Center, San Francisco, California, USA

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                  1391.    Evaluation of Anatomic Variation in Macromolecule Contribution to the GABA Signal

                              Using Metabolite Nulling and the J-Editing Technique at 3.0 T

 

Lawrence S. Kegeles1, Xiangling Mao2, Robyn Gonsalez1, Dikoma C. Shungu2

1Columbia University, New York, New York, USA; 2Weill Medical College of Cornell University, New York, New York, USA

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                  1392.    Is Spending Extra Scan Time on Measuring a `Macromolecules-Only' Signal Worthwhile?

 

Hérald Rabeson1, Hélène Ratiney1, Enrico Capobianco2, Ron de Beer3, Dirk van Ormondt3, Danielle Graveron-Demilly1

1CNRS UMR5012, Villeurbanne, France; 2Consorzio  21 & CRS4, Pula (Cagliari), Italy; 3Delft University of Technology, Delft, Netherlands

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                  1393.    Pitfalls and Advantages of Different T2 Correction Strategies for the Absolute Quantification of

                              Choline, Creatine, N-Acetil Aspartate in Human  Grey Matter by 1H-MRS

 

Emil Malucelli1, Claudia Testa1, Caterina Tonon1, Raffaele Lodi1, Bruno Barbiroli1, Stefano Iotti2

1Università di Bologna, Italy; 2Università di Bologna, Bologna, Italy, Italy

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                  1394.    Resampling Strategies to Estimate Mean Concentrations from Low SNR In Vivo MR Spectra

 

Gunther Helms1, Ivanka Savic2, Peter Dechent1

1University of Göttingen, Faculty of Medicine, Göttingen, Germany; 2Karolinska Institutet, Stockholm, Sweden

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                  1395.    Comparison of Quantification of Clinical MR Spectra by LCModel and the Scanner System Software

 

Zili Chu1, 2, Zhiyue Jerry Wang1, 2, Jon Chia3, Jill V. Hunter1, 2

1Texas Children's Hospital, Houston, Texas, USA; 2Baylor College of Medicine, Houston, Texas, USA; 3Philips Medical Systems, Cleveland, Ohio, USA

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                  1396.    Lower Glutamate Levels in the Anterior Cingulate Cortex of Chronic Cocaine Users:

                              A Proton MRS Study Using TE-Averaged PRESS at 3T with a Modified Glutamate Quantification Strategy

 

Shaolin Yang1, Betty Jo Salmeron1, Thomas J. Ross1, Zheng-Xiong Xi1, Elliot A. Stein1, Yihong Yang1

1National Institute on Drug Abuse, Baltimore, Maryland, USA

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                  1397.    Improved Procedure for Automatic Alignment of Strongly Overlapping Peak-Regions in

                              High-Resolution 1H NMR Spectra

 

Qi Zhao1, Radka Stoyanova2, Nicole Clarke3, István Pelczer3, Truman R. Brown1

1Columbia University, New York, New York, USA; 2Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA; 3Princeton University, Princeton, New Jersey, USA

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                  1398.    Reproducibility of In Vivo GABA Quantification in Anterior Cingulate at 3 Tesla

 

Malgorzata Marjanska1, Pierre-Gilles Henry1, Edward J. Auerbach1, Daniel Franc1, Bryon Mueller1, Kamil Ugurbil1, Kelvin O. Lim1

1Unviersity of Minnesota, Minneapolis, Minnesota, USA

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                  1399.    Quantification of Co-Edited Macromolecules in GABA J-Editing

 

Jan Willem C van der Veen1, Noriaki Hattori2, Jun Shen1

1NIH, NIMH, Magnetic Resonance Spectroscopy Core, Bethesda, Maryland, USA; 2NIH, NINDS, Bethesda, Maryland, USA

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                  1400.    Improved MR Spectral Analysis for a PFC-Filled Endorectal Prostate Surface Coil Compared to

                              an Air-Filled Coil

 

Gavin Hamilton1, Michael S. Middleton1, Sang-Hee Choi1, Nouha Salibi2, Robert F. Mattrey1

1University of California, San Diego, San Diego, California, USA; 2Siemens Medical Solutions, Malvern, Pennsylvania, USA

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                  1401.    Quantitative J-Resolved Prostate Spectroscopy Using Two-Dimensional Prior-Knowledge Fitting

 

Thomas Lange1, Rolf Feodor Schulte1, Peter Boesiger1

1University and ETH Zurich, Zurich, Switzerland

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                  1402.    Bootstrap in MRSI: A Non-Parametric Way to Assess Quantification Standard Error

 

Hélène Ratiney1, SungWon Chung1, Roland G. Henry1, Radhika Srinivasan1, Sarah J. Nelson1, Daniel Pelletier1

1University of California San Francisco, San Francisco, California, USA

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                  1403.    Improved Proton NMR Thermometry by Field Inhomogeneity Correction Post-Processing

 

Mingming Zhu1, 2, Adil Bashir2, Joseph J. H. Ackerman1, 2, Dmitriy A. Yablonskiy, 12

1Washington University in St Louis, Saint Louis, Missouri, USA; 2Washington University School of Medicine, Saint Louis, Missouri, USA

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                  1404.    Classification of the Quality of In Vivo 1H Spectra from Human Brain Tumours Using ICA

 

Alan R. Wright1, John R. Griffiths2, Franklyn A. Howe1

1St George's, University of London, London, UK; 2Cancer Research UK Cambridge Reseach Institute, Cambridge, UK

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                  1405.    Fast Absolute Quantitation Using FID Echo Planar Chemical Shift Imaging (FID EP-CSI)

 

Melvyn Boon King Ooi1, Yingli Yang1, Srirama V. Swaminathan, 12, Truman R. Brown1

1Columbia University, NYC, New York, USA; 2Philips Medical Systems, Cleveland, Ohio, USA

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                  1406.    Feasibility of Using Predicted Cramer Rao Lower Bounds for the Design of

                              Optimized In Vivo MR Spectroscopy Sequences Targeting Multiple Metabolites

 

Daniel GQ Chong1, Johannes Slotboom2, Roland Kreis1

1University Berne, Berne, Switzerland; 2Inselspital Berne, Berne, Switzerland