| Weekday Educational
Course: |
| Imaging Biomarkers 1 & 2 |
| Organizers: H. Cecil
Charles, Ph.D., and Jeffrey L.
Evelhoch, Ph.D. |
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| Skill Level: Basic |
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| Wednesday, 22 April and Thursday, 23 April 2009 |
| 13:30 - 15:30 |
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| OVERVIEW |
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This course will introduce
biomarker principles, how imaging is used as a biomarker
in general and how imaging biomarkers are used in
several specific diseases. It is comprised of two,
two hour sessions with four presentations (followed by
short question and answer periods) by scientists and
physicians actively involved in the use of MR biomarkers in
each session. The first session will provide a broad
introduction to biomarkers (both imaging and non-imaging),
how they are used, how they are qualified to be fit for
their intended use and what is needed to implement MR
biomarkers in a multi-center clinical trial. The second
session will present examples of how imaging biomarkers
(including, but not limited to MR) are used in multiple
sclerosis, oncology, cardiovascular diseases and
neurodegenerative diseases. |
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| EDUCATIONAL OBJECTIVES
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Upon completion of this
case based session, participants should be able to:
- Describe what a biomarker is and how magnetic
resonance can be used as a biomarker;
- Explain how biomarkers are qualified to be fit for their
intended purpose;
- Review what is required to use MR biomarkers in both
preclinical studies and clinical trials; and
- Give examples of how imaging biomarkers are being used in
at least two of the following
areas: multiple sclerosis, oncology, cardiovascular diseases
and neurodegenerative diseases.
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| Wednesday, 22 April 2009 |
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Introduction to Imaging Biomarkers |
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| 13:30 |
What Imaging
Biomarkers Are and How They Are Used |
John C. Waterton, Ph.D. |
| 14:00 |
Non-Imaging
Biomarkers and Regulatory Aspects of Imaging Biomarkers |
Jeffrey
L. Evelhoch, Ph.D. |
| 14:30 |
Preclinical
Applications of Imaging Biomarkers |
Markus
von Kienlin, Ph.D. |
| 15:00 |
Imaging Biomarkers
in Neurodegenerative Diseases |
Clifford
R. Jack, Jr., M.D. |
| 15:30 |
Adjournment |
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| Thursday 24 April 2009 |
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Imaging Biomarkers in Practice
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| 13:30 |
Quantitative MR in
Multi-Center Clinical Trials |
Edward
Ashton, Ph.D. |
| 14:00 |
Imaging Biomarkers
in Multiple Sclerosis |
Massimo
Filippi, M.D. |
| 14:30 |
Imaging Biomarkers
in Oncology |
Daniel
C. Sullivan, M.D. |
| 15:00 |
Imaging Biomarkers
in Cardiovascular Disease |
Chun
Yuan, Ph.D. |
| 15:30 |
Adjournment |
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