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Postdoctoral Position in Laser-Polarized 129 Xe NMR/MRI |
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A postdoctoral position is available in the Structure and
Dynamics by Magnetic Resonance Laboratory from Science Matter Division,
and the Nuclear Magnetic Resonance Laboratory (LRMN), NeuroSpin, CEA,
Saclay, France (http://www-dsv.cea.fr)
under the supervision of Patrick Berthault and Luisa Ciobanu. The
appointment will be made for a period of 12 months, starting
immediately. The position will be to work on an ANR funded project to perform in vivo laser-polarized 129Xe molecular imaging experiments. In this project, after optical pumping, laser-polarized xenon is encapsulated in cage-molecules functionalized with biological ligands and transported to the receptors of interest where it is imaged. The project involves collaboration with chemists (synthesis of cage-molecules of high affinity for xenon), biochemists (choice of the biological systems and of the ligands) and spectroscopists (handling of the hyperpolarized gas in fast imaging experiments). The candidate will participate in the installation and
optimization of the optical pumping setup designed to deliver high
quantities of hyperpolarized xenon. He/she will be in charge of the
spectroscopy and imaging experiments on small animals, in close
collaboration with all partners. The MR experiments will be implemented
on a 7T animal imager. |