ISMRM SCIENTIFIC WORKSHOP ~ 06-09 November 2014

Magnetic Resonance in Cancer: Challenges & Unmet Needs
Austin, TX, USA

 

PROGRAM

click on to see the syllabus contribution/abstract and to view the recorded presentation


DAY 1 - Thursday, 6 November 2014 (no CME available)
         
15:00     Registration & Speaker Upload Available until 18:00  
 18:00     Welcome Opening Reception  
         

DAY 2 - Friday, 7 November 2014 (6.00 CME available)
         
07:00     Registration & Speaker Upload Available until 08:30; Breakfast served until 09:00
08:30   Welcome  
         
      Session 1: MR & PET: Impact on Cancer Staging
      Moderators: Paula J. Foster, Ph.D. & Donna H. Murrell, B.Sc.(Hons)  
09:00 PET/MRI: Facts & Fictions Gustav K. von Schulthess, M.D., Ph.D.
University Hospital Zürich
Zürich, Switzerland
09:30 Prostate Cancer Metabolic Imaging Claudia Testa, Ph.D.
University of Bologna
Bologna, Italy
      Proffered Papers – Oral Session  
09:45 The Utility of High b-Value Diffusion Weighted MRI in Predicting High Grade Prostate Cancers in the Peripheral Zone Harsh K. Agarwal, Ph.D.
Philips Research
Bethesda, MD, USA
10:00 Feasibility of Simultaneous 18F-FACBC PET/MRI in High Risk Prostate Cancer Patients Kirsten Margrete Selnæs, Ph.D.
Norwegian University of Science & Technology
Trondheim, Norway
10:15 Pilot Study: MRI Changes Associated with Dutasteride & Finasteride Treatments in Patients with Low Risk Prostate Cancer Olga Starobinets, M.Sc.
University of California
San Francisco, CA, USA
10:30     Break  
         
      Session 2: Detecting Cancer Initiating Cells; Circulating Cancer Cells & Cancer Dormancy
      Moderators: Kristine Glunde, Ph.D. & Amanda M. Hamilton, Ph.D.  
11:00 In Vivo Magnetic Resonance Imaging of Cells in Parenchymal & Vascular Compartments: Opportunities & Challenges Piotr Walczak, M.D., Ph.D.
Johns Hopkins Univ. School of Medicine
Baltimore, MD, USA
11:30   MicroNMR Technology for Cancer Detection - permission withheld Hakho Lee, Ph.D.
Harvard University
Cambridge, MA, USA
      Proffered Papers – Oral Session  
11:45 Nanoparticles Coated with the Tumor-Penetrating Peptide iRGD Inhibit Experimental Breast Cancer Metastasis to the Brain Amanda M. Hamilton, Ph.D.
Robarts Research Institute
London, ON, Canada
12:00 Development of Quantitative Multi-Parametric MRI Models for Prostate Cancer Detection using Registered Correlative Pathology Gregory J. Metzger, Ph.D.
University of Minnesota
Minneapolis, MN, USA
12:15 Imaging Based, Histology Trained Maps (IBHTMS) of Brain Tumor Cellularity Predict Tumor Presence In Pathologically Confirmed Regions Sampled Ex-Vivo Peter S. LaViolette, Ph.D.
Medical College of Wisconsin
Milwaukee, WI, USA
12:30     Lunch & Speaker Upload Available  
         
      Session 3: Tumor Microenvironment – Interplay Between Cancer Cells, Macrophages, Vasculature & Hypoxia
Moderators: Arvind P. Pathak, Ph.D. & Asif Rizwan, Ph.D.
14:00   MR Imaging of the Tumor Microenvironment - permission withheld Heike Daldrup-Link, M.D., Ph.D.
Lucile Packard Children’s Hospital
Stanford, CA, USA
14:30 MR Imaging to Improve Our Understanding of How the Tumor Micro-Environment Promotes Progression & Obstructs Treatment
 
Moriel H. Vandsburger, Ph.D.
University of Kentucky
Lexington, KY, USA
      Proffered Papers – Oral Session  
14:45 Prediction of Treatment Response in Pancreatic Cancer Using EPR Oxygen Imaging Murali K. Cherukuri, Ph.D.
National Institutes of Health
Bethesda, MD, USA
15:00 Combined Magnetic Resonance Spectroscopy & Mass Spectrometric Imaging of Hypoxia Asif Rizwan, Ph.D.
Johns Hopkins Univ. School of Medicine
Baltimore, MD, USA
15:15 Quantitative Oxygen-Enhanced Magnetic Resonance Imaging (OE-MRI) Biomarkers of Tumor Response to Radiation Derek White, M.Sc.
University of Texas Southwestern Medical Center
Dallas, TX, USA
15:30     Break & Speaker Upload Available  
         
      Session 4: Cancer Treatment Response: Can MR Aid in Adaptive Therapy?
Moderators: Patrick Bolan, Ph.D. & Nassim Tayari, M.Sc.
16:00 Imaging of the Treatment Response in Cancer: From Cytotoxic Agents to Signal Transduction Inhibitors Natalie J. Serkova, Ph.D.
University of Colorado
Denver, CO, USA
16:30 Selective Acidification & De-Energization of Tumors with Lonidamine for Sensitization to Chemotherapy Kavindra Nath, Ph.D.
University of Pennsylvania
Philadelphia, PA, USA
      Proffered Papers – Oral Session  
16:45 MRI of Liposomal Delivery of SPIO Nanoparticles to Breast Cancer Models Dmitri Artemov, Ph.D.
Johns Hopkins Univ. School of Medicine
Baltimore, MD, USA
17:00 Insights from a Gamma Knife® Radiation Necrosis Mouse Model

 

Carlos J. Perez-Torres, Ph.D.
Washington University
St. Louis, MO, USA
17:15 Detection of Tumor Progression in Patients with Glioblastomas using DTI & DSC-MRI Sumei Wang, M.D.
University of Pennsylvania
Philadelphia, PA, USA
17:30     Adjournment  
         
19:00     Dinner  
         
         

DAY 3 - Saturday, 8 November 2014 (6.75 CME available)
         
07:00     Registration, Speaker Upload Available & Breakfast Served until 08:30  
08:25   Introduction to Negendank Lecture  
08:30 Negendank Lecture: Imaging Lipids & What They Can Tell Us About Cancer E. Jim Delikatny, Ph.D.
University of Pennsylvania
Philadelphia, PA, USA
09:15     Break & Speaker Upload Available  
         
      Session 5: Spectroscopy in Clinical Cancer: Are We There Yet?
Moderators: Marnix C. Maas, Ph.D. &
Harish Poptani, Ph.D.
09:30 Clinical Applications of MRS in Oncology: Problems & Progress Peter B. Barker, D.Phil.
Johns Hopkins Univ. School of Medicine
Baltimore, MD, USA
10:00 1H-MRSI in Prostate Cancer Management: Opportunities, Challenges & Developments Marnix C. Maas, Ph.D.
Radboud University
Nijmegen, The Netherlands
      Proffered Papers – Oral Session  
10:15 Evaluation of Lipid Composition in the Breast Using Multiple Gradient Echo MRI Melanie Freed, Ph.D.
NYU School of Medicine
New York, NY, USA
10:30 Absolute Choline Concentration Mapping for Prostate Cancer Localization Using Water Unsuppressed 1H MR Spectroscopy Nassim Tayari, M.Sc.
Radboud University Medical Centre
Nijmegen, Netherlands
10:45 High Resolution Whole Brain 3D Echo Planar Spectroscopic Imaging for Detection of Pseudo-Progression in Gliobastoma Patients Gaurav Verma, Ph.D.
University of Pennsylvania
Philadelphia, PA, USA
11:00     Break & Speaker Upload Available  
11:15     Poster Session (no CME available)  
13:00     Lunch & Speaker Upload Available  
         
      Session 6: Heteronuclear & 2D NMR in Cancer Revisited - Clinical/Pre-Clinical
Moderators: Henk M. De Feyter, Ph.D. & E. Jim Delikatny, Ph.D.
14:00 Biochemical Characterization of Cancer Using Multi-dimensional MR Spectroscopic Imaging M. Albert Thomas, Ph.D.
David Geffen School of Medicine
Los Angeles, CA, USA
 14:30 Non-Proton MR Imaging Armin Michael Nagel, Dr.Rer.Nat.
German Cancer Research Center
Heidelberg, Germany
      Proffered Papers – Oral Session  
14:45 Detection of Intra- & Extracellular Lactate in Cell Suspensions with Hyperpolarized 13C NMR Vincent Breukels, Ph.D.
Radboud University Medical Centre
Nijmegen, Netherlands
15:00 Oxidative Ketone Body Metabolism in Rat Brain Tumors & the Effect of the Ketogenic Diet: Evidence from In Vivo 13C MRS Henk M. De Feyter, Ph.D.
Yale University
New Haven, CT, USA
15:15 Real Time Measurement of Hyperpolarized Lactate Production & Efflux as a Biomarker of Tumor Aggressiveness in a MR Compatible 3D Cell & Tissue Culture Bioreactor Renuka Sriram, Ph.D.
University of California
San Francisco, CA, USA
15:30     Break & Speaker Upload Available  
         
      Session 7: Cancer MRI/MRS at 7T – Potential & Challenges
Moderators: Tom W. J. Scheenen, Ph.D. & Gaurav Verma, Ph.D.
16:00 Cancer MRI/MRS at 7T – Potential & Challenges Dennis W. J. Klomp, Ph.D.
University Medical Center Utrecht
Malden, The Netherlands
16:30 7T MRI/MRS When Imaging the Effects of Therapy of Brain Tumors Janine M. Lupo, Ph.D.
University of California
San Francisco, CA, USA
      Proffered Papers – Oral Session  
16:45 Combined PGSE & OGSE DWI for Characterization of Extracellular Space (ECS) in GL261 GBM Model Olivier Reynaud, Ph.D.
NYU Langone Medical Center
New York, NY, USA
17:00 Advancing the Early Detection & Diagnosis of Primary & Recurring Thyroid Cancers Using a Molecularly Targeted T2-Exchange MRI Contrast Agent Todd C. Soesbe, Ph.D.
University of Texas Southwestern Medical Center
Dallas, TX, USA
17:15 Assessment of Membrane Fluidity Using Nuclear Overhauser Enhancement Mediated Magnetization Transfer (NOE-Mediated MT) Xiaoyong Zhang, Ph.D.
Vanderbilt University
Nashville, TN, USA
         
17:30     Session 8: Working Group Sessions  
      • High Field MRI/MRS
• Diffusion MRI – Data Acquisition & Analysis
• Perfusion Imaging – Data Acquisition & Analysis
• Novel Contrast Including MTR, CEST & APT
• Integrating MRI/MRS in Clinical Trials
 
18:15     Adjournment  
         
19:00     Dinner Banquet  
         
         

DAY 4 – Sunday, 9 November 2014 (3.00 CME available)
         
07:00     Registration, Speaker Upload Available & Breakfast Served until 08:30  
         
08:25   Young Investigator Poster Awards  
         
      Session 9: Emerging Contrast Mechanisms for Cancer Imaging
Moderators: Joel R. Garbow, Ph.D. & Ashley Stokes, Ph.D.
08:30 Can MR Contrast Agents Compete with Other Modalities for Molecular Imaging of Cancer? A. Dean Sherry, Ph.D.
UT Southwestern Medical Center
Dallas, TX, USA
09:00 Non-Invasive Redox CEST MRI as a Potential Endogenous Imaging Biomarker for In Vivo Redox States Kejia Cai, Ph.D.
University of Illinois
Chicago, IL, USA
      Proffered Papers – Oral Session  
09:15 Feasibility & Reproducibility of R2* & R1 Measurements Under Oxygen & Carbogen Challenge in Healthy Volunteers & Patients with Hepatocellular Carcinoma at 1.5 T & 3T Octavia Bane, Ph.D.
Icahn School of Medicine at Mount Sinai
New York, NY, USA
09:30 Characterization of Cancer Onset & Development using Diffusion Weighted MRI in a Transgenic Mouse Model of Prostate Cancer Deborah K. Hill, Ph.D.
Norwegian University of Science & Technology
Trondheim, Norway
09:45 MR Elastography in Glioma: Feasibility & Initial Comparison with Tumor Grade Kay M. Pepin, B.Sc.
Mayo Clinic
Rochester, MN, USA
10:00     Break & Speaker Upload Available  
         
      Session 10: New Perspectives in Cancer Metabolism
Moderators:
Deborah K. Hill, Ph.D. & Kayvan R. Keshari, Ph.D.
10:30

Magnetic Resonance Spectroscopy Studies of Mutant IDH Cells

Sabrina M. Ronen, Ph.D.
University of California
San Francisco, CA, USA
11:00 The Potential & Challenges of High Resolution Magic Angle Spinning MR in Characterization of Breast Cancer Maria Dung Cao, Ph.D.
Norwegian University of Science & Technology
Trondheim, Norway
      Proffered Papers – Oral Session  
11:15 Dual-Modality Molecular Imaging of Choline Kinase Expression & Inhibition in a Breast Cancer Model Sean P. Arlauckas, B.S.E.
University of Pennsylvania
Philadelphia, PA, USA
11:30 Combining Magnetic Resonance Spectroscopic Imaging & Mass Spectrometric Imaging Reveals Protein Biomarkers of Aggressive Breast Cancer Lu Jiang, Ph.D.
Johns Hopkins Univ. School of Medicine
Baltimore, MD, USA
11:45 Pretherapeutic Lactate Levels Measured by MR-Spectroscopy Can Predict the Pattern of Progression in Recurrent Glioblastoma Under Antiangiogenic Therapy with Bevacizumab Katharina J. Wenger, M.D.
University Hospital Frankfurt
Frankfurt, Germany
12:00     Adjournment/Boxed Lunches  
         
         

The International Society for Magnetic Resonance in Medicine is accredited byby
the Accreditation Council for Continuing Medical Education to
provide continuing medical education for physicians.