PROGRAM

 
   
  Saturday, 14 February 2009
   
17:00 - 20:00 Registration
18:00 - 20:00 Reception
   
  Day 1, Sunday, 15 February 2009
   
07:30 Registration
   
08:30 Introductory Remarks by Felix Wehrli, Ph.D., University of Pennsylvania, Philadelphia, PA, USA, , and Ravinder Reddy, Ph.D., University of Pennsylvania, Philadelphia, PA, USA
   
08:45 - 12:00  Session I - Biochemistry, Structure and Function of Cartilage, Session Chair:  Ravinder Reddy, Ph.D.
   
08:45 Biochemistry, Biomechanics and Mechanisms of Cartilage Degeneration: Implications for Osteoarthritis
  Steven B. Abramson, M.D., NYU Medical Center, New York, NY, USA
   
09:10 Engineered  and Stem Cell Derived Cartilage for Tissue Repair: Role of Imaging
  Brian Johnstone, Ph.D., Oregon Health & Science University, Portland, OR, USA
   
09:35 Break
   
09:55 Order and Function of Connective Tissues by Multiple Quantum NMR
  Gil Navon, Ph.D., Tel Aviv University, Tel Aviv, Israel
   
10:20 Diagnostic Imaging of Cartilage, Current Status
  Garry E. Gold, M.D., Stanford University, Stanford, CA, USA
   
Contributed Papers (six papers, each 10 minutes +2 min discussion)
   
10:45 Longitudinal Analysis of Knee Cartilage T2 Laminar Organization in a Subset of Patients from the Osteoarthritis Initiative
Julio Carballido-Gamio, Ph.D., University of California - San Francisco, San Francisco, CA USA
   
10:57 Cartilage T2 Mapping Using Loading in situ MRI in Early Osteoarthritis with Hip Dysplasia
Takashi Nishii, M.D.,
Osaka University Medical School, Osaka, Japan
   
11:09 Quantitative Magnetization Transfer SSFP Cartilage Imaging
Monika Gloor, University of Basel, University Hospital, Basel, Switzerland
   
11:21 A New Short TE 3D Radial MRI Sequence: SWIFT-LiTE
Jang-Yeon Park, Ph.D., University of Minnesota, Minneapolis, MN USA
   
11:33 Quantitative MRI of Early Osteoarthritis in the Canine Stifle
Ute Goerke, CMRR/University of Minnesota, Minneapolis, MN USA
   
11:45 Feasibility and Reproducibility of T1 MRI Examining Osteoarthritis in a Guinea Pig Model
Matthew Fenty, B.S., University of Pennsylvania, Philadelphia, PA USA
   
12:00 Lunch
   
13:30 - 15:30  Session II - Diagnostic Imaging of Cartilage and Clinical Studies, Session Chair:  Garry Gold, M.D.
   
13:30 Collagen Changes and the Role of T2 Mapping
  Timothy J. Mosher, M.D., Penn State College of Medicine, Hershey, PA, USA
   
13:55 Assessment of Treatment Response in OA and RA
  Philipp Lang, M.D., M.B.A., Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
   
14:20 Image Based Assessment of Cartilage Morphology in OA Patients
  Felix Eckstein, M.D., Ph.D., Paracelsus Private Medical University, Salzburg, Austria
   
14:45 Structural Imaging of Connective Tissue in vivo: Sequences with New Contrast and High Resolution
  Garry E. Gold, M.D., Stanford University, Stanford, CA, USA
   
15:10 Break
   
15:30 - 18:25  Session III - Technical Developments in Cartilage Imaging, Session Chair:  Felix Eckstein, M.D., Ph.D.
   
15:30 Molecular Imaging in Cartilage by Multinuclear MRI
  Walter Witschey, B.S., University of Pennsylvania, Philadelphia, PA, USA
   
15:55 Contrast Enhanced MRI and its Role in Imaging of Cartilage
  Miika T. Nieminen, Ph.D., Oulu University Hospital, Oulu, Finland
   
16:20 In vivo Assessment of Connective Tissues by Ultra-short TE MRI
  Graeme M. Bydder, M.B., Ch.B., University of California San Diego, San Diego, CA, USA
   
16:45 7 Tesla Imaging of the Articular Cartilage and Other Tissues in the Joint
  Sharmila Majumdar, Ph.D., University of California, San Francisco, San Francisco, CA, USA
   
Contributed Papers (six papers, each 10 minutes +2 min discussion)
   
17:10 Cartilage Bound Pool Fraction Maps In Vivo
Nikola A. Stikov, M.Sc., Stanford University, Stanford, CA USA
   
17:22 T1rho MRI of Arthroscopic Grade I and II Cartilage Degeneration in 6 Patients
Walter R.T. Witschey, B.S.,  University of Pennsylvania, Philadelphia, PA USA
   
17:34 T1p Sequences as Predictors of Proteoglycan Content in Articular Cartilage
Kathryn Keenan, M.S., Stanford University, Stanford, CA USA
   
17:46 Time and Power Efficiency of Multishot and Steady-State T1ρ MRI in 7 T Joint Imaging
Walter R.T. Witschey, B.S.,  University of Pennsylvania, Philadelphia, PA USA
   
17:58 T2 and T2* Measurements of the Menisci and Femorotibal Cartilage at 7.0 Tesla: Preliminary Results
Klaus Friedrich, M.D.
   
18:10 MRI of the Wrist at 7 Tesla Using an 8 Channel Array Coil and Parallel Imaging: Preliminary Results
Gregory Chang, M.D., NYU Medical Center, New York, NY USA
   
   
  Day 2, Monday, 16 February 2009
   
08:15 - 12:00  Session IV - Biology, Chemistry, Structure and Function of BoneSession Chair:  Felix Wehrli, Ph.D.
   
08:15 Osteoporosis: A Brief Update on the Cell Biology
  Nancy E. Lane, M.D., University of California at Davis, Sacramento, CA, USA
   
08:45 Biomechanical Implications of Bone Micro- and Ultrastructure
  Daniel P. Nicolella, Ph.D., Southwest Research Institute, San Antonio, TX, USA
   
09:15 Solid State MR Spectroscopy and Imaging of Bone Mineral and Matrix
  Jerome L. Ackerman, Ph.D., Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA
   
09:45 Break
   
10:15 MR Imaging and Spectroscopy of Bone Marrow
  Fritz Schick, M.D., Ph.D., University of Tübingen, Tübingen, Germany
   
10:45 Advanced Imaging of Bone Macro and Micro Structure
  Harry Genant, M.D., University of California San Francisco, San Francisco, CA, USA
   
Contributed Papers (five papers, each 10 minutes +2 min discussion)
   
11:15 Assessment of Cortical Bone Structure with FSE, 2D and 3D UTE Sequences
Jiang Du, Ph.D., University of California - San Diego, San Diego, CA USA
   
11:27 Differences Between Weight-Bearing Patellofemoral Joint Kinematics and Static Joint Alignment
Christine E. Draper, M.S., Stanford, University Stanford, CA USA
   
11:39 From Imaging Data to Patient-Specific Modeling for a Large Number of Femur Geometries: Definition of a Smooth Workflow
Marc Horner, Ph.D., ANSYS, Evanston, IL USA
   
11:51  MRI and PET Perfusion Kinetics in Advanced Osteoarthritis of the Dunkin-Hartley Guinea Pig: A Pilot Study
Jonathan P. Dyke, Ph.D., Weill Cornell Medical College, New York, NY USA
   
12:03 SWIFT: a Novel Method for Musculoskeletal Magnetic Resonance Imaging of Extremely Fast Relaxing Spins
Jutta Ellermann, M.D., Ph.D., University of Minnesota, Minneapolis, MN USA
   
   
12:15 Lunch
   
13:30 - 15:45  Session V - Technical and Clinical Aspects of Imaging Bone Structure and Function, Session Chair:  Sharmila Majumdar, Ph.D.
   
13:30 MRI-Based Virtual Bone Biopsy: Principles and Applications
  Jeremy Magland, Ph.D., University of Pennsylvania, Philadelphia, PA, USA
   
14:00 The Pros and Cons of MRI and CT for the Assessment of Corital and Trabecular Structure
  Thomas Link, M.D., University of California San Francisco, San Francisco, CA, USA
   
14:30 Potential of MRI for Indirect Assessment of Bone Micro- and Ultrastructure
  Hee Kwon Song, Ph.D., University of Pennsylvania, Philadelphia, PA, USA
   
Contributed Papers (five papers, each 10 minutes +2 min discussion)
   
15:00 16 Channel, Bell Shaped Surface Coil for Knee Imaging
Modhurin Banerjee-Snyder, Ph.D., GE Healthcare, Aurora, OH USA
   
15:12 Rapid High Resolution Whole Knee Assessment Using Radial LC-SSFP with Parallel Imaging
Jessica L. Klaers, M.S., University of Wisconsin - Madison, Madison, WI USA
   
15:24 Rapid Estimation of Cartilage T2 Based on Double Echo at Steady State (DESS) at 3T
Goetz H. Welsch, M.D., Medical University of Vienna, Vienna, Austria
   
15:36 Evaluating a Novel Positioning Device in Magnetic Resonance Imaging (MRI) of the Wrist
Anshul Rastogi, MBBS, MRCP, Kennedy Institute of Rheumatology, London, United Kingdom
   
15:48 Quantification of 3D Radial Undersampling Artifact to Obtain High Quality Isotropic Resolution (0.36 mm) for Volumetric Cartilage Assessment
Jessica L. Klaers, M.S., University of Wisconsin - Madison, Madison, WI USA
   
   
16:00 Break
   
16:20 - 18:30  Session VI - Image Based Assessment of Fracture Risk & Treatment Efficacy, Session Chair:  Jerome Ackerman, Ph.D.
   
16:20 In vivo Imaging of Trabecular Bone Structure for Fracture Discrimination
  Masako Ito, M.D., Ph.D., Nagasaki University, Nagasaki, Japan
   
16:50 The Role of Structural Imaging for Monitoring Treatment Responsible in Osteoporosis
  Sundeep Khosla, M.D., Mayo Clinic, Rochester, MN, USA
   
17:20 Can Images Predict Bone Mechanical Competence in Patients?
  X. Edward Guo, Ph.D., Columbia University, New York, NY, USA
   
   
  Day 3, Tuesday, February 17, 2009
   
08:15 - 12:15  Session VII - Multimodality Imaging of Muscle and Other Tissues, Session Chair:  Chris Boesch, M.D., Ph.D.
   
08:15 Biology, Physiology and Function of Muscle: Muscular Dystrophy
  Glenn Walter, Ph.D., University of Florida, Gainesville, FL, USA
   
08:40 MRI Studies of Muscle Mechanics
  Klaas Nicolay, Ph.D., Eindhoven University of Technology, Eindhoven, The Netherlands
   
09:05 MR Spectroscopy of Muscle Physiology in Health and Disease
  Chris Boesch, M.D., Ph.D., University of Bern, Bern, Switzerland
   
09:30 Advances in Diagnostic Imaging of Orthopedic Muscle Disorders
  Juerg Hodler, M.D., Department of Radiology, Balgrist University Hospital, Zurich, Switzerland
   
09:55 Break
   
10:15 Quantification of Skeletal Muscle Perfusion and Oxygenation
  Pierre G. Carlier, M.D., Ph.D., Institute of Myology, Paris, France
   
10:40 MRI and MRS of the Intervertebral Disc
  Ari Borthakur, Ph.D., University of Pennsylvania, Philadelphia, PA, USA
   
Contributed Papers (six papers, each 10 minutes +2 min discussion)
   
11:05 Preliminary Results Evaluating Muscle Function in Mice Lacking Myostatin: a mpf-NMR Study
Claire Wary, Ph.D.
   
11:17 Assessment of Inververtebral Disc via CEST 
Wen Ling, Ph.D., University of Minnesota, Minneapolis, MN USA
   
11:29 in vivo Magnetization Transfer Ratio Mapping of Human Intervertebral Disc
Chenyang Wang, B.S., University of Pennsylvania, Philadelphia, PA USA
   
11:41 Correlation of Intervertebral Disc T1ρ Relaxation Measurement with Osmotic Pressure
Chenyang Wang, B.S., University of Pennsylvania, Philadelphia, PA USA
   
11:53 Comparison of Discography Opening Pressure to T1r Relaxation in the Inter-Vertebral Disc in vivo
Matthew Fenty ,B.S., University of Pennsylvania, Philadelphia, PA USA
   
12:15 Break
   
13:15 - 16:30  Session VIII - Role of Imaging in MSK Drug Discovery, Session Chairs:  Philip Land, M.D., M.B.A., and Harry Genant, M.D.
   
13:15 Pharma Industry Perspectives of the Role of Imaging in Drug Development
  Salvatore Alesci, M.D., Ph.D., Wyeth Research, Collegeville, PA, USA
Bernhard Dardzinski, Ph.D., Merck Research Labs, West Point, PA, USA
Yuying C. Hwang, Ph.D., Amgen Inc., Thousand Oaks, CA, USA
Michael B. Smith, Ph.D., Novartis Institutes for BioMedical Research, Inc., Cambridge, MA, USA
   
14:15 Roundtable discussion
   
Contributed Papers (four papers, each 10 minutes +2 min discussion)
   
15:15 Quantitative DCE-MRI of The Spine
Andreas F. Biffar, Dipl.Phys., Klinikum der Universität München München, Germany
   
15:27 Pixel-by-Pixel ADC Measurements in In-Vivo Study of Lumbar Intervertebral Disc Degeneration 
Hon Yu, Ph.D., University of California, Irvine, Irvine, CA USA
   
15:39 Association between Vertebral Endplate-Perfusion and Intervertebral Disc Degeneration
Hon Yu, Ph.D., University of California, Irvine, Irvine, CA USA
   
16:30 Adjournment
   
POSTER SESSION
  Comparing Parameters of Muscle VX2Tumor Vascularization in Rabbits Assessed by Contrast-enhanced Ultrasonography and Dynamic Enhanced MRI
Guo Liang,
First Affiliated Hospital of Soochow, University Suzhou, China
   
  Eliminating Signal Contamination from Olefinic Fat in Skeletal Muscle Diffusion-Weighted Imaging
Dimitrios Karampinos, University of Illinois at Urbana-Champaign, Urbana, IL USA
   
  Neural Network Approach for a Robust ROI Segmentation System for Electron Magnetic Resonance Color Tomograms
Christopher Dharmaraj, Ph.D.,
National Cancer Institute, Bethesda, MD USA
   
  T1 and T2 Relaxation Times of Musculoskeletal Tissues at 7T MRI
Seungbum Koo, Ph.D., Stanford University, Stanford, CA USA
   

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