The 4th workshop
of the ISMRM White Matter Study Group will address MRI-detectable changes in
the aging brain pertaining both to successful aging and age-related
pathological states, with particular emphasis on the cerebral white matter.
Age-related pathological conditions of the brain include a large group of
diseases that pose challenges in terms of diagnosis and interpretation, and
that are increasingly making use of MRI as a source of surrogate markers of
disease progression. Age-related pathologies discussed in this
workshop will specifically include neurodegenerative and neuroinflammatory
conditions impacting cognition and motor performance in the elderly.
This disease group encompasses Alzheimer's Disease, cerebrovascular
diseases, and other pathologies that are severely disabling to older
patients and of enormous socio-economic impact, given the shift in the
population's age structure towards higher life expectancy. The varied
pathogenic mechanisms involved offer a unique framework to improve our
understanding of how histopathological alterations determine physical MR
properties.
The relevance of both conventional and advanced MR techniques, as well as
image analysis will be emphasized in two special technology workshop
sessions including case studies. Poster sessions, including poster
presentations over lunch, will be targeted to enhance the exposure and
participation of younger scientists and students. |