MR Spectroscopy of Brain: Animal Models

Hall C
Tuesday: 13:30 – 15:30

1066.   Can Cross Relaxation Between Solid and Water Protons Account for T2 Relaxation Times in Brain?  I.M. Vavasour and A.L. MacKay, University of British Columbia Hospital, Vancouver, BC, Canada.
1067.   Quantitative Analysis of Human and Macaque Brain Metabolites Using 3 Tesla System, N. Hattori, N. Inoue, S. Yoshikubo, M. Umeda, M. Fukunaga, C. Tanaka, S. Naruse, T. Sawada and R.T. Engelhardt, BF Research Institute, Osaka, Japan; Meiji University of Oriental Medicine and Kyoto Prefectural University of Medicine, Kyoto, Japan and GE Yokogawa Medical Systems, Tokyo, Japan.
1068.   Localized ²³Na-NMR Spectroscopy of the Rat Brain Using Shift Reagent: Measuring Cerebral Blood Volume Changes During Hypercapnia, I. Ronen, H. Merkle and S-G. Kim, University of Minnesota, Minneapolis, MN, USA.
1069.   Spatially Resolved ¹³C Turnover in Rat Brain at 7 Tesla with ICED PEPSI, F. Hyder, R. Renken, K.L. Behar and D.L. Rothman, Yale University, New Haven, CT, USA and University of Groningen, Groningen, The Netherlands.
1070.   Cerebral Metabolic Maps by ¹H[¹³C] NMR at 7 Tesla, F. Hyder, P. Brown, T.W. Nixon and K.L. Behar, Yale University, New Haven, CT, USA.
1071.   Proton Localized 2D Spectroscopy in the Rat Brain at 7T, F. Delmas, B. Gillet, B-T. Doan, J-C. Beloeil, P. Méric and J-L. Correze, ICSN-CNRS, Gif sur Yvette, France and CHU Villemin, Paris, France.
1072.   Detection of Mobile Lipids Following Cerebral Infarction by 1D and 2D Proton MR Spectroscopy in a Rat Brain Slice Model, G.D. Graham, W. Ahmed, G.A. Rosenberg and C.C. Gasparovic, University of New Mexico School of Medicine and Albuquerque VA Medical Center, Albuquerque, NM, USA.
1073.   Lactate and NAA Imaging - Predictors of Tissue Recovery After Thrombolytic Stroke Intervention. A Spectroscopic Imaging Study In Rat Brain, C. Franke, G. Brinker, F. Pillekamp and M. Hoehn, Max-Planck-Institute for Neurological Research, Cologne, Germany.
1074.   Postmortem Stability of ¹H MRS Metabolites in Rat Brain, C.C. Cloak, L. Chang, T. Ernst and R.E. Poland, Harbor-UCLA Medical Center, Torrance, CA, USA and Cedars-Sinai Medical Center, Los Angeles, CA, USA.
1075.   Choline Metabolism and Betaine Synthesis in Rat Brain, R. Katz-Brull, A.R. Koudinov, M. Segal and H. Degani, Weizmann Institute of Science, Rehovot, Israel.
1076.   Brain Metabolite Levels Are Altered in a Rat Model of Autism: An In Vivo ¹H MRS Study, A. Tudorica, F. Johnston, D. Kahne, H. Li, T. Button, C. Geronimo, P. Whitaker-Azmitia and W. Huang, State University of New York, Stony Brook, NY, USA.
1077.   Studies of Thiamine Deficient Rat Brains with in vivo and in vitro Proton NMR Spectroscopy, H. Lee, G. Holburn, P.R. Martin and R. Price, Vanderbilt University Medical Center, Nashville, TN, USA.
1078.   Maternal Glycemic Control in Diabetic Pregnancy: its Effect on Cerebral Glucose Metabolism in the Fetus, S. Haber and A. Lapidot, Weizmann Institute of Science, Rehovot, Israel.
1079.   Effects of Acute and Chronic Nicotine on ¹H MRS in the Anterior Cingulate, T.J. Ross, E. Schnieder, R. Prost, S-J. Li, R.C. Risinger, B.J. Salmeron, A.S. Bloom and E.A. Stein, Medical College of Wisconsin, Milwaukee, WI, USA and Pfizer Central Research, Groton, CT, USA.
1080.   Behavioural Deficits Correlate with MRS Changes in Mice, A.M. Blamire, A. Vincent, R. Deacon, S. Pendlebury, C. Salmon, H. Johannsen-Berg, B. Rajagopalan, J. Stein and P. Styles, University of Oxford, Oxford, UK.
1081.   Oral Cortisol and Psychosocial Stress Differently Alter Brain Metabolism in Tree Shrews, T. Michaelis, G. de Biurrun, T. Watanabe, E. Fuchs and J. Frahm, Biomedizinische NMR Forschungs GmbH and Deutsches Primatenzentrum, Göttingen, Germany.
1082.   Effects of Antipsychotic Drugs on Metabolite Ratios in Rat Brain In Vivo, D.M. Lindquist, R.M. Hawk, C.N. Karson and R.A. Komoroski, University of Arkansas at Little Rock; Central Arkansas Veterans Healthcare System and University of Arkansas for Medical Sciences, Little Rock, AR, USA.
1083. 19F NMR Study of Trifluoperazine Crossing Blood-Brain-Barrier Due to P-Glycoprotein Modulation, P. Wang, A. Aszalos and J.A. Vick, Howard University, Washington, DC, USA and Food and Drug Administration, Laurel, MD, USA.
1084.   Metabolic Investigation of Neuronal Dysfunction Induced by 3-Nitropropionic Acid in Rats and Primates, C. Dautry, F. Vaufrey, E. Brouillet, N. Bizat, F. Condé, P. Hantraye and G. Bloch, SHFJ, DRM, CEA, Orsay, France.
1085.   Impact of Acute Reversible Hydrocephalus in Guinea Pigs: A Proton MRI/MRS Study, S. Yamada, G. McComb, J-H. Hwang, M. Shibata, S. Bluml and B.D. Ross, Rudi Schulte Research Institute, Santa Barbara, CA, USA; Huntington Medical Research Institutes, Pasadena, CA, USA; Children’s Hospital of Los Angeles and University of Southern California, Los Angeles, CA, USA.
1086.   The Sequential Proton MRS and Diffusion Studies of Kaolin-Induced Hydrocephalic Cat Brain, Y. Chang, Y.S. Kim, M.J. Kim, S.K. Hwang, B.S. Han and D.S. Kang, Kyungpook National University Hospital, Taegu, Korea.
1087.   Effects of Deep Hypothermic Circulatory Arrest on Brain Metabolism Monitored by In Vivo ¹H and ³¹P Magnetic Resonance Spectroscopy in a Feline Model, M.G. Song, S.J. Choo, K.H. Lim, H.C. Ha, I.C. Choi, S.H. Park, J.W. Lee, H. Song, J.H. Lee and T.H. Lim, Asan Medical Center, University of Ulsan College of Medicine and Asan Institute for Life Sciences, Seoul, Korea.
1088.   Cerebral Glucose Metabolism in a Transgenic Animal Model of ALS as Detected by In Vivo ¹³C MRS, E.H.G.K. Küstermann, O. Andreassen, F. Beal and B.G. Jenkins, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA and University of Nottingham, Nottingham, UK.
1089.   MRI/MRS of a Mouse Model for Canavan Disease, M. Quast, J. Wei, E.L. Ezell, P.L. Rady, K.A. Platt, H.B. Skinner, G.A. Campbell, K. Matalon, J. Ceci, S.K. Tyring, M. Nehls, S. Szucs and R. Matalon, The University of Texas Medical Branch, Galveston, TX, USA.
1090.   In Vivo ¹H MR Spectroscopic Analysis of Apoptosis in Hypoxic-Ischemic Newborn Rats, K-S. Kim, S-J. Park, K.H. Lim, E-J. Kim, J.H. Lee and S-Y. Pi, Asan Medical Center, University of Ulsan College of Medicine and Asan Institute for Life Sciences, Seoul, Korea.
1091.   Decreased Cerebral N-Acetylaspartate Correlates with Reduced Brain Water Apparent Diffusion Coefficient During Delayed Energy Failure in the Newborn Piglet, J.S Thornton, M. Wylezinska, R.J. Ordidge, K. Brooks, E.B. Cady, M. Clemence, Q. Nguyen, M. Noone, F.E. O'Brien, N. Parker, Y. Sakata, M.W. Sellwood, R. Springett and J.S. Wyatt, University College London, London, UK.
1092.   Proton T2 Relaxation Measurements of Cerebral Metabaolites in a Newborn Piglet Hypoxia-Ischemia Model, C.M.P.C.D. Peeters, K.P.J. Braun, F. Groenendaal and K. Nicolay, Wilhelmina Children's Hospital and University of Utrecht, Utrecht, the Netherlands.
1093.   Investigation of Hypoxic Ischemic Injured Newborn Rat Brain by In Vivo ¹H MR Spectroscopy, S-Y. Pi, K-S. Kim, J-H. Yoon, H-S. Yoon, K.H. Lim, E-J. Kim and J.H. Lee, Asan Medical Center, University of Ulsan College of Medicine and Asan Institute for Life Sciences, Seoul, Korea.
1094.   [3-¹³C]Lactate Metabolism in the Rat Brain: An Ex-Vivo Study, A-K. Bouzier, E. Thiaudière, M. Biran, P. Canioni and M. Merle, Université Victor Segalen, Bordeaux, France.
1095.   Fast ¹³C-Glucose Metabolite Mapping in Rat Brain Using ¹H Echo Planar Spectroscopic Imaging Technique, S. Morikawa, T. Inubushi, H. Ishii and T. Sawada, Shiga University of Medical Science, Shiga, Japan.

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