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Understanding Diffusion Tensor Imaging and Functional MRI: The Relationship Between Structure and Function in the Brain
Gareth G. Barker, Ph.D., and R. Todd Constable, Ph.D., Organizers

Last updated 05 May 2009

Course Description
This four-hour course will focus on the rapidly evolving fields of diffusion tensor imaging (DTI) and functional MRI (fMRI) and will highlight the principles and practices of how and why each are performed.  It will focus particularly on the various aspects of brain connectivity highlighted by each technique, and on methods of integrating this complementary information.
Audience Description:  This course is aimed at both new and experienced researchers and clinicians.  Attendees will be a mix of graduate students, postdoctoral students, clinicians and researchers.  Clinicians who may be considering applications in neurological MRI could greatly benefit from this course.  No prior knowledge of the methodology is required.
It will also appeal to researchers with prior experience in one of these techniques, who are interested, for example, in extending their knowledge of structural connectivity mapped via DTI to functional relationships explored via fMRI, or vice versa.

Educational Objectives:
Upon completion of this session, participants should be able to:

Explain how the fMRI data is acquired and processed;
Explain how the diffusion tensor is acquired, measured and mapped;
Define the terms structural and functional connectivity;
Describe sources of artifacts, limitations to the data, and the likely impact of new parallel imaging techniques on fMRI and DTI data;
Outline the methods available to combine the complementary information from fMRI and DTI data.

The final five minutes of each presentation will be reserved for questions.

Tuesday, 18 May
Introduction to fMRI
07:00 fMRI Basics: Paradigm Design/Analysis R. Todd Constable
07:30 fMRI Resting State Connectivity/Structural Equation Modeling Mark J. Lowe
Wednesday, 19 May
Introduction to DTI
07:00 DTI Basics Derek K. Jones
07:30 Tractography and Beyond Geoff Parker
Thursday, 20 May
Artifacts...and Correction Strategies
07:00 DTI Christopher A. Clark
07:30 fMRI Douglas C. Noll
Friday, 21 May
Quantitative Measures/Information Obtained
07:00 DTI: b-Values, Fractional Anisotropy and Other Quantitative Measures Peter J. Basser
07:30 fMRI/DTI - Combining Data Mark R. Symms