Clinical Neurospectroscopy

Room B 210-211         16:30 - 18:30                                            Chairs: Quihong He and Dikoma Shungu

16:30         136.      Multi-Modality MR Approach to Assess Metabolism and Perfusion in the Human Brain During Hypoglycemia

Marinette van der Graaf1, Bastiaan E. de Galan1, Dennis W.J. Klomp1, Laura M. Parkes2, Cees J.J. Tack1,

Arend Heerschap1

1Radboud University Nijmegen Medical Center, Nijmegen, Netherlands; 2Radboud University Nijmegen, Nijmegen, Netherlands


16:42         137.      Early Proton Magnetic Resonance Spectroscopy in Newborn Infants with Perinatal Cerebral Hypoxic-Ischemic Injury: Metabolite Peak-Area Ratios, Relaxation Times, Concentrations and Concentration Ratios.

Jeanie LY Cheong1, Ernest B. Cady2, Juliet Penrice1, John S. Wyatt1, I Jane Cox3, Nicola J. Robertson1

1University College London, London, UK; 2University College London Hospitals NHS Trust, London, UK; 3Hammersmith Hospital, Imperial College London, London, UK


16:54         138.      In Vivo Glycine Detection with TE-Averaged 1H-MRS - not available

Andrew P. Prescot1, Blaise deB Frederick1, Yong Ke1, John Brown2, Liqun Wang2, Marc J. Kaufman1,

Perry F. Renshaw1

1McLean Hospital, Belmont, Massachusetts, USA; 2GlaxoSmithKline, Greenford, London, UK


17:06         139.      Quantitative Proton MRS of Pelizaeus-Merzbacher Disease: Evidence for Dys- And Hypomyelination - not available

Peter Dechent1, Knut Brockmann1, Petra Pouwels2, Steffi Dreha-Kulaczewski1, Gunther Helms1, Bernd Wilken1,

Folker Hanefeld1, Jens Frahm2

1Medical Faculty, University Göttingen, Göttingen, Germany; 2MPI for Biophysical Chemistry, Göttingen, Germany


17:18         140.      Acute Disseminated Encephalomyelitis: Evaluation with Proton MR Spectroscopic Imaging - not available

Anna Gambini1, Sayed A. Fatemi1, Thomas O. Crawford1, Eric H. Kossoff1, Alena Horska1, Peter B. Barker1

1Johns Hopkins University, Baltimore, Maryland, USA


17:30         141.      Detection of Axonal Damage in the Spinal Cord in Multiple Sclerosis by Magnetic Resonance Spectroscopy

Andrew M. Blamire1, Zaheer Cader2, Martin Lee2, Jackie Palace2, Paul M. Matthews2

1University of Newcastle upon Tyne, Newcastle upon Tyne, Northumberland, UK; 2University of Oxford, Oxford, UK


17:42         142.      Macromolecular and Lipid Contributions in Short Echo Time 1H MRS at 4 Tesla: 1) Reliability in Normal Controls and 2) Comparative Study Between Amyotrophic Lateral Sclerosis Patients and Controls - not available

Lana G. Kaiser1, Karl Young1, Brian J. Soher2, Michael W. Weiner1

1University of California San Francisco, San Francisco, California, USA; 2University of Miami, Miami, Florida, USA


17:54         143.      Traumatic Brain Injury: 3 Tesla Magnetic Resonance Spectroscopic Imaging and Cognitive Function

William Miles Brooks1, Cary Savage1, Robin Aupperle1, Thomas Malone1, Allan Schmitt1, JoAnn Lierman1,

Anda Popescu1, Mihai Popescu1

1University of Kansas Medical Center, Kansas City, Kansas, USA


18:06         144.      Correlation of Quantitative in Vivo 1H MRS of Untreated Pediatric Medulloblastoma with Quantitative Histological Features

Xiaodong Liu1, Ignacio Gonzalez-Gomez1, Ashok Panigrahy1, Mark D. Krieger1, Gordon J. McComb1,

Marvin D. Nelson1, Floyd H. Gilles1, Stefan Bluml1,2

1Childrens Hospital Los Angeles, Los Angeles, California, USA; 2Rudi Schulte Research Institute, Santa Barbara, California, USA


18:18         145.      Proton MRSI Biomarkers Predict Survival in Children with CNS Tumors - not available

Loukas G. Astrakas1,2, David Zurakowski, 2,3, Karen J. Marcus, 2,4, Maria K. Zarifi1,5, Umberto DeGirolami, 2,6,

Peter McL Black, 2,4, Nancy J. Tarbell, 2,7, A. Aria Tzika1,2

1Massachusetts General Hospital, Boston, Massachusetts, USA; 2Harvard Medical School, Boston, Massachusetts, USA; 3The Children’s Hospital, Boston, Massachusetts, USA; 4The Children’s Hospital, Dana Farber Cancer Institute, Brigham & Women's Hospital, Boston, Massachusetts, USA; 5Agia Sophia Children's Hospital, Athens, Attiki, Greece; 6The Children's Hospital, Brigham & Women's Hospital, Boston, Massachusetts, USA; 7Massachusetts General Hospital, Dana Farber Cancer Institute, Boston, Massachusetts, USA