Novel and Smart Contrast Agents

Room A 104-105         16:30 - 18:30                                       Chairs: Brian D. Ross and Dara Kraitchman

16:30         166.      In Vivo Tracking of Gene Delivery Modules to Central Nervous System Using a Novel Susceptibility MRI Contrast Agent - not available

Young Kim1, Christina Liu1, Shuning Huang1, Bruce Rosen1, Philip Liu1

1MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA


16:42         167.      Novel “Smart” 1H MRI Contrast Agents for Assessing LacZ Gene Expression

Jian-Xin Yu1, Li Liu1, Vikram D. Kodibagkar1, Weina Cui1, Robert D. Gerard1, Ralph P. Mason1

1University of Texas Southwestern Medical Center, Dallas, Texas, USA


16:54         168.      19F CSI of Gene-Reporter Molecule OFPNPG - not available

Vikram D. Kodibagkar1, Jianxin Yu1, Li Liu1, Hoby P. Hetherington2, Stephen L. Brown3, Robert D. Gerard1,

Ralph P. Mason1

1University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA; 2Albert Einstein College of Medicine, Bronx, New York, USA; 3Henry Ford Health System, Detroit, Michigan, USA


17:06         169.      Persistent Anti-Angiogenic Effectiveness in Early Atherosclerosis Following a Single ανβ3-Targeted Administration of Fumagillin Paramagnetic Nanoparticles at 1.5 T - not available

Patrick M. Winter1, Anne M. Morawski, Shelton D. Caruthers 2, Thomas D. Harris3, Grace Hu, Ralph W. Fuhrhop, Huiying Zhang, John S. Allen, Elizabeth K. Lacy, Todd A. Williams, Samuel A. Wickline, Gregory M. Lanza

1Washington University, St. Louis, Missouri, USA; 2Philips Medical Systems, Cleveland, Ohio, USA; 3Bristol-Myers Squibb Medical Imaging, Billerica, Massachusetts, USA


17:18         170.      Molecular MR Imagining of the Estrogen Receptor Using a Novel Contrast Agent - not available

Erez Eyal1, David Milstein1, Hadassa Degani1, Sarbani Mukhopadhyay1, Dalia Seger1, Raanan Margalit1,

Ronit Hirsch1, Yehoshua Ben-David1, Edna Furman-Haran1

1Weizmann Institute of Science, Rehovot, Israel


17:30         171.      Development of 13C and 15N Contrast Agents Employing PASADENA - not available

Pratip Bhattacharya1,2, Daniel P. Weitekamp1, Kent C. Harris2, Alexander Peter Lin3, Brian D. Ross, 1,2

1California Institute of Technology, Pasadena, California, USA; 2Huntington Medical Research Institutes, Pasadena, California, USA; 3Rudi Schulte Research Institute, Pasadena, California, USA


17:42         172.      Quantifying Exchange Rates in CEST Agents Using Saturation Time and Saturation Power Dependencies of the Magnetization Transfer Effect (QUEST and QUESP) - not available

Michael T. McMahon1,2, Assaf A. Gilad1, Jinyuan Zhou1,2, Jeff W.M. Bulte1, Peter C.M. van Zijl1,2

1Johns Hopkins School of Medicine, Baltimore, Maryland, USA; 2Kennedy Krieger Institute, Baltimore, Maryland, USA


17:54         173.      Characterization of HE-24.8: A New Contrast Agent for Experimental Magnetic Resonance Angiography

Fabian Maximilian Kiessling1, Melanie Heilmann1, Peter Peschke1, Karel Ulbrich2, Vladimir Subr2, Twan Lamers1, Lothar Schad, Wolfhard Semmler1

1German Cancer Research Center, Heidelberg, Germany; 2Institute of Macromolecular Chemistry, Prague, Czech Republic


18:06         174.      Characterization of Relaxational Properties of New Bis-Hydrazide-Gd-DTPA-Complexes as Contrast Agents for Molecular MRI

Timo Dansauer1, Ekkehard Kuestermann1, Dorit Kemken1, Dieter Leibfritz1

1University of Bremen, Bremen, Germany


18:18         175.      Comparision of Poly(L-Glutamic Acid)Gd (III)-DOTA Conjugate with Degradable and Non-Degradable Spacers for Magnetic Resonance Imaging

T. Ke1, Y. Feng1, F. Ye1, J. Guo1, D. L. Parker1, Z-R. Lu1

1University of Utah, Salt Lake City, Utah, USA