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MRS of GABA, Glutamate
and Glutathione: Detection Methods, Sensitivity Enhancement and Brain Mapping
Room 613 - 614
11:00 - 13:00
Chairs: Ralph E. Hurd and Melissa J. Terpstra
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Time |
Prog # |
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11:00 |
484. |
Rapid Brain Glutamate
Mapping in Central and Peripheral Gray Matter at 3 and 4 Tesla Using
Short TE Proton-Echo
Planar-Spectroscopic
Imaging (PEPSI)
Stefan Posse1,
2, Ricardo Otazo1, 3, Arvind Caprihan1,
4, Juan Bustillo2, Hongji Chen2, Chun Zuo5,
Perry Renshaw5, Vincent
Magnotta6,
Bryon Mueller7, Kelvin O. Lim7, Kamil Ugurbil7,
Paul Mullins1, Charles Gasparovic1,
Jeffry R. Alger8
1The
MIND Institute, Albuquerque, New Mexico, USA; 2University of
New Mexico School of Medicine, Albuquerque, New Mexico, USA; 3University
of New Mexico, Albuquerque, New Mexico, USA; 4New Mexico
Resonance, Albuquerque, New Mexico, USA; 5Harvard University,
Boston, Massachusetts, USA; 6University of Iowa, Iowa City,
Iowa, USA; 7University of Minnesota, Minneapolis, Minnesota,
USA; 8University of California in Los Angeles, Los Angeles,
California, USA |
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11:12 |
485. |
Glutamate Levels in Normal
Appearing White and Gray Matter in Multiple Sclerosis Using TE-Averaged MRSI at
3T
Radhika
Srinivasan1, Sarah Nelson1, Stephen Hauser1,
Daniel Pelletier1
1University
of California, San Francisco, California, USA |
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11:24 |
486. |
Gender, Age and Regional
Differences of Brain Glutamate Concentration in Healthy Subjects
Napapon Sailasuta1,
Thomas Ernst1, Linda Chang1
1John
A, Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA |
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11:36 |
487. |
Measurement of Heterogeneous
Distribution of GABA in Gray and White Matters in the Human Brain Using
Selective
Multiple Quantum Chemical
Shift Imaging of GABA
In-Young Choi1,
2, Sang-Pil Lee1, 2, Hellmut Merkle3, Jun
Shen3
1University
of Kansas Medical Center, Kansas City, Kansas, USA; 2The Nathan Kline
Institute, Orangeburg, New York, USA; 3NIH, Bethesda, Maryland, USA |
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11:48 |
488. |
Evaluation of GABA Detection
Sensitivity Gains Achieved with an 8-Channel Phased-Array Head Coil at 3.0 T in
the Human
Dorsolateral Prefrontal
Cortex Using the J-Editing Technique
Dikoma C. Shungu1,
Xiangling Mao1, Lawrence S. Kegeles2
1Weill
Medical College of Cornell University, New York, New York, USA; 2College
of Physicians and Surgeons of Columbia University, New York, New York, USA |
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12:00 |
489. |
Test-Retest Reliability of
Dorsolateral Prefrontal Cortical GABA Measurement Using an 8-Channel
Phased-Array Head Coil
with the J Editing Technique
at 3T
Lawrence S. Kegeles1,
Xiangling Mao2, Jonathan Dyke2, Robyn Gonzales1,
Tacara N. Soones1, Dikoma C. Shungu, 12
1Columbia University,
New York, New York, USA; 2Weill Medical College of Cornell
University, New York, New York, USA |
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12:12 |
490. |
Residual Water as a Navigator
in GABA Editing Spectroscopy
Jan Willem
W.C. van der Veen1, Jun Shen1
1NIH, NIMH, Bethesda,
Maryland, USA |
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12:24 |
491. |
In Vivo Evaluation of
the Concentration of Macromolecule Species Involved in GABA Editing
Changho Choi1,
Nicholas J. Coupland1, Paramjit P. Bhardwaj1, Nikolai
Malykhin1, Dan Gheorghiu1, Peter S. Allen1
1University
of Alberta, Edmonton, Alberta, Canada |
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12:36 |
492. |
Simultaneous Detection of
Unobstructed Glutamate and Glutamine Using Standard STEAM with Optimized
Sequence
Parameters at 3, 4, 4.7, 7,
and 9.4 Tesla - A Simulation Study
Shaolin Yang1, Jiani
Hu2, Elliot A. Stein1, Yihong Yang1
1National
Institute on Drug Abuse, NIH, Baltimore, Maryland, USA; 2Wayne State
University, Detroit, Michigan, USA |
| 12:48 |
493. |
Double Edited NMR Spectroscoy
for Detection of an Antioxidant Profile in the Human Brain In Vivo
Melissa Terpstra1,
Rolf Gruetter1
1University
of MN, Minneapolis, Minnesota, USA |
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