MRS Sensitivity Enhancement

MRS Sensitivity Enhancement Techniques for 13C and Other Nuclei through Hyperpolarization

Room 611 - 612 16:30 - 18:30 Chairs: Rolf Gruetter and Brian D. Ross

Time	Prog #
16:30	*584.*	Metabolic Imaging with Hyperpolarized ¹³C and Multi-Echo, Single-Shot RARE Sven Månsson¹, Jochen Leupold², Oliver Wieben³, René In't Zandt⁴, Peter Magnusson⁴, Edvin Johansson⁴, John Stefan Petersson⁴ ¹Malmö University Hospital, Malmö, Sweden; ²University Hospital Freiburg, Freiburg, Germany; ³University of Wisconsin, Madison, Wisconsin, USA; ⁴Amersham Health R&D, Malmö, Sweden
16:42	*585.*	Fast Chemical Shift Imaging of Hyperpolarized ¹³C Substrates Alexander Peter Lin¹,², Thao T. Tran¹, Pratip Bhattacharya,²³, Kent Harris³, Brian David Ross³ ¹Rudi Schulte Research Institute, Pasadena, California, USA; ²California Institute of Technology, Pasadena, California, USA; ³Huntington Medical Research Institutes, Pasadena, California, USA
16:54	*586.*	Carbon-13 Metabolic Imaging at 3T Using Hyperpolarized 13C-1-Pyruvate Susan J. Kohler¹, YiFen Yen¹, Jan Wolber², Rene in't Zandt², Andreas Gram², Fredrik Ellner², Mikkel Thaning², Albert Chen³, Mark Albers³, Robert Bok³, James Tropp⁴, Sarah Nelson³, Daniel Vigneron³, John Kurhanewicz³, Ralph Hurd¹ ¹GE Healthcare, Menlo Park, California, USA; ²GE Healthcare, Malmo, Sweden; ³University of California San Francisco, San Francisco, California, USA; ⁴GE Healthcare, Fremont, California, USA
17:06	*587.*	High-Resolution Hyperpolarized C-13 Spectroscopic Imaging of the TRAMP Mouse at 3T Albert P. Chen¹,², Mark Albers¹,², Susan J. Kohler³, Yi-fen Yen³, Ralph E. Hurd³, James Tropp³, Pieter Pels¹, Matthew L. Zierhut¹,², Robert Bok¹, Sarah J. Nelson¹,², John Kurhanewicz¹,², Daniel B. Vigneron¹,² ¹UCSF, San Francisco, California, USA; ²UCSF/UCB, San Francisco, California, USA; ³GE Healthcare, Menlo Park, California, USA
17:18	*588.*	Limits of Detection of Hyperpolarized ¹³C In Vitro and In Vivo Brian David Ross¹, Alexander Peter Lin²,³, Pratip Bhattacharya¹,³, Kent Harris¹, Keiko Kanamori¹, Anna Freundlich², Thao Tran² ¹Huntington Medical Research Institutes, Pasadena, California, USA; ²Rudi Schulte Research Institute, Pasadena, California, USA; ³California Institute of Technology, Pasadena, California, USA
17:30	*589.*	Polarization Transfer for Sensitivity-Enhanced Spectroscopy Using a Single RF Transmit-Channel on (Clinical) MR Systems Dennis W.J. Klomp¹, Arno P.M. Kentgens², Arend Heerschap¹ ¹Radboud University Nijmegen Medical Center, Nijmegen, Netherlands; ²Radboud University Nijmegen, Nijmegen, Netherlands
17:42	*590.*	¹³C Spectroscopic Imaging of Glycogen in Rat Brain Hongxia Lei¹,², Rolf Gruetter¹,² ¹EPFL, Lausanne, Switzerland; ²University of Minnesota, Minneapolis, Minnesota, USA
17:54	*591.*	*Hunting for Cerebral [2-¹³C]GABA Signal Derived In Vivo* from Glia-Specific Substrate [2-¹³C]acetate** Jehoon Yang¹, Shizhe Steve Li¹, Stephen Fox², John Bacher³, Robert B. Innis¹, Jun Shen¹ ¹NIMH, Bethesda, Maryland, USA; ²NCI, Frederick, Maryland, USA; ³ORS, Bethesda, Maryland, USA
18:06	*592.*	Non-Linear Effects of Strong Coupling in ¹³C Edited ¹H NMR Spectra Obtained Without Decoupling Julien Valette¹, Fawzi Boumezbeur¹, Malgorzata Marjanska², Kâmil Ugurbil², Vincent Lebon¹, Pierre-Gilles Henry² ¹CEA-SHFJ, Orsay, France; ²CMRR, University of Minnesota, Minneapolis, Minnesota, USA
18:18	593.	Simultaneous Observation of Lungs and Brain to Enhance Versatility of 129Xe Washout Curve Analysis in Mouse Brain Hideaki Fujiwara¹, Takashi Masutani², Michiko Narazaki², Hirohiko Imai², Tetsuya Wakayama², Atsuomi Kimura² ¹Osaka University, Suita, Osaka, Japan; ²Osaka University, 1-7 Yamadaoka, Suita, Osaka, Japan