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Stroke Imaging
Weili Lin, A. Gregory Sorensen, Organizers

Thursday, 11 May 2006, 10:30 - 12:30
Last updated 20 February 2009

This two-hour course encompasses several aspects of MR imaging for acute stroke. Although this course will mainly focus on clinical aspects, underlying biological factors of neuroprotection and its potential implications will be introduced and discussed. Building on the biological aspects, the current status of several clinical trials where MR imaging plays a critical role will be reported. In particular, several lines of evidence using newer therapeutic interventions have suggested that the therapeutic window can potentially be extended beyond the currently approved 3hrs for tPA. This extended time window could have profound implications and potentially modify the generally held view of the role of MR in acute stroke management. In addition, 3T MR has become more widely available; there is an increasing need to assess how a higher field strength can offer additional information that may be of critical importance for acute stroke management. Finally, the development of future MR acute stroke protocols will be outlined.
Educational Objectives:
Upon completion of this session, participants should be able to:
• Describe the underlying biological factors associated with neuroprotection and its potential implications for MRI;
• Recognize the status of currently ongoing clinical trials where MR plays a critical role;
• Determine how MR can potentially be further utilized for imaging acute stroke patients;
• Evaluate whether or not a higher field strength is beneficial for the management of acute stroke patients; and
• Identify the needed new MR technologies to further improve the management of acute stroke patients.


Thursday, 11 May
10:30 Neuroprotection: Biological Background and MR Implications Michael Chopp
10:55 The Current Status of Ongoing Clinical Trials: Beyond 3 Hours Howard A. Rowley
11:20 The Perspective of Pathophysiology - Guided Stroke Therapy Arno Villringer
11:45 MR Wish List for Stroke Neurologists: What Are We Missing? Jeffrey Saver
12:10 Questions and Answers
12:30 Adjournment