Monitoring Anti-Cancer Therapy Response in the Clinic

Dachgarten     13:30 - 15:30         Chairs: N.R. Jagannathan and Hendrik Von Tengg-Kobligk


Prog #

13:30 555.

Bayesian Mixed-Effect Model for Breast Cancer Treatment Studies

Volker J. Schmid1, Brandon Whitcher2, N.Jane Taylor3, Anwar R. Padhani3, Guang-Zhong Yang1

1Imperial College, London, UK; 2GlaxoSmithKline, London, UK; 3Mount Vernon Hospital, Northwood, UK


13:40 556.

Quantitative MR Spectroscopy to Monitor Treatment Response of Breast Cancer to Neoadjuvant Chemotherapy

Hyun-Man Baik1, Jeon-Hor Chen1, 2, Hon J. Yu1, Rita S. Mehta1, Orhan Nalcioglu1, Min-Ying Su1

1University of California-Irvine, Irvine, California, USA; 2China Medical University Hospital, Taichung 404, Taiwan


13:50 557.

2D MRSI in Locally Advanced Breast Cancer: Assessment of Tumor Response in Patients Undergoing

Neo-Adjuvant Chemotherapy

K A. Danishad1, V Seenu1, N R. Jagannathan1

1All India Institute of Medical Sciences, New Delhi, Delhi, India

14:00 558.

Quantitative Analysis of MRI Tumor Characteristics for Neoadjuvant Chemotherapy Response Prediction in

Breast Cancer to the First-Line Doxorubicin-Cyclophosphamide Regimen and the AC Followed by Taxane Regimen

Ke Nie1, Jeon-Hor Chen1, 2, Hon J. Yu1, Yong Chu1, Rita S. Mehta1, Orhan Nalcioglu1, Min-Ying Su1

1Tu & Yuen Center for Functional Onco-Imaging, University of California, Irvine, California, USA; 2Department of Radiology, China Medical University Hospital, Taichung 404, Taiwan

14:10 559.

Does Diffusion Weighted Imaging Have a Role in Predicting Response to Neoadjuvant Chemotherapy?

Martin D. Pickles1, Peter Gibbs1, Martin Lowry1, Lindsay W. Turnbull1

1University of Hull, Hull, East Yorkshire, UK

14:20 560.

Diffusion-Weighted MR Imaging of Colorectal Liver Metastases: Repeatability and Reproducibility of

Apparent Diffusion Coefficients and Implications for Therapeutic Monitoring

Keiko Miyazaki1, Erica Scurr2, David Collins1, Nandita deSouza1, Martin O. Leach1, Dow-Mu Koh1, 2

1Institute of Cancer Research, Sutton, Surrey, UK; 2Royal Marsden Hospital, Sutton, Surrey, UK

14:30 561.

DCE-MRI Parameters Are Predictive of Tumour Regression in Cervix Cancer

Mark A. Zahra1, Evis Sala1, Andrew N. Priest1, Martin J. Graves1, Andrew B. Gill2, Sandeep S. Gupta3, Li Tee Tan2, Mark Arends1, Robin AF Crawford2, James D. Brenton1, David J. Lomas1

1University of Cambridge, Cambridge, UK; 2Addenbrooke's Hospital, Cambridge, UK; 3National Naval Medical Center, Bethesda, Maryland, USA

14:40 562.

Dynamic Contrast Enhanced MRI of Solid Tumors Treated with NGR-TNF, a Novel Vascular Targeting Agent

Hanneke W.M. van Laarhoven1, Jacques A. van Asten1, Carla M.L. van Herpen1, Salvatore Toma2, Claudio Bordignon2, Cornelis J.A. Punt1, Arend Heerschap1

1Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; 2Molmed, Italy

14:50 563.

Prediction of Response to AC Chemotherapy Based on Early Changes in Size and Pharmacokinetic Parameters

 After 1 Cycle Treatment

Hon Yu1, Jeon-Hor Chen1, 2, Ke Nie1, Rita Mehta1, Orhan Nalcioglu1, Min-Ying Su1

1University of California, Irvine, California, USA; 2China Medical University Hospital, Taichung, Taiwan


15:00 564.

Dynamic Contrast-Enhanced MRI and Vessel Size Imaging Sensitively Indicate Antiangiogenic Therapy Effects on

Tumor Xenografts in Mice

Stefan Zwick1, 2, Eva Christina Woenne2, Ralph Strecker1, Michael Bock2, Arne Hengerer1, Matthias Taupitz3, Joerg Schnorr, 34, Bernd Misselwitz5, Wolfhard Semmler2, Fabian Kiessling2

1Siemens Medical Solutions, Erlangen, Germany; 2German Cancer Research Center, Heidelberg, Germany; 3Charité, Berlin, Germany; 4Ferropharm, Teltow, Germany; 5Schering, Berlin, Germany


15:10 565.

DCE-MRI Analysis of Radiotherapy and Combretastatin-A4-Phosphate (CA4P) Effects on the Cancerous Prostate Gland

Henry Mandeville1, N. Jane Taylor1, Quan Sing Ng1, Peter J. Hoskin1, Jessica Milner1, J. James Stirling1, James A. d'Arcy2, David J. Collins2, Michele I. Saunders1, Anwar R. Padhani1

1Mount Vernon Hospital, Northwood, Middlesex, UK; 2Royal Marsden NHS Foundation Trust, Sutton, Surrey, UK

15:20 566.

Assessment of Treatment Response with Functional Magnetic Resonance Imaging in Metastatic Thyroid Carcinoma

Jiachao Liang1, Johannnes Heverhagen2, Steffen Sammet1, Guang Jia1, Xiangyu Yang1, Regina Koch1, Manisha Shah1, Michael V. Knopp1

1The Ohio State University, Columbus, Ohio, USA; 2Philipps University, Marburg, Germany