Imaging Reorganization and Plasticity in the Brain  
Alberto Bizzi, M.D., and P. Ellen Grant, M.D., M.Sc., Organizers  
Skill Level: Intermediate  


This two-hour course will focus on the neuronal mechanisms responsible for recovery of brain function in patients with neurological diseases. Reorganization is the process of reorganizing connections and re-coordinating a network of areas while function is recovering. Recovery of function seems to imply a successful "reconnection" and recoordination of a network of areas.

Advanced imaging methods such as fMRI and DTI offer the unique opportunity for measuring changes in functional segregation and connectivity that accompany and underpin behavioral changes and functional improvements after brain injury.

Educational Objectives

Upon completion of this course participants should be able to:
  Describe the neural mechanisms responsible for recovery of function after injury to the brain;
  Compare functional imaging methods used to evaluate brain reorganization and monitor it over time; and
  Design a study that will quantitatively measure changes in brain reorganization and will correlate these changes with clinical measures
  of improvements in brain function.

Audience Description

The clinical categorical courses are designed for clinical radiologists, neuroradiologists, neurosurgeons, neurologists, cardiologists, oncologists, practicing clinicians and scientists, from beginning to advanced experience levels working in MR.

The final five minutes of each presentation will be reserved for questions.  
10:30 Imaging sensorimotor reorganization after stroke and implications  Nick Ward, M.D.
for rehabilitation  
11:00 fMRI of Language Reorganization in Children with Brain Lesions Wolfgang Grodd, M.D.
11:30 Dynamics of language reorganization after stroke Cornelius Weiller, M.D.
12:00 Exploring neuroanatomical basis for brain recovery with DTI Marco Catani, M.D.
12:30 Adjournment