Magnetic Resonance in Clinical Trials

Organizers: Michael V. Knopp and John Kurhanewicz
Skill level: Basic

Tuesday, 22 May



This course is designed to provide valuable information concerning the use of magnetic resonance biomarkers in clinical trials. The expert speakers will identify what constitutes a good MR biomarker, with a focus on practical utility and regulatory issues.  There will also be a “roundtable discussion” with the goal of sharing personal experiences using MR biomarkers in clinical trials.

Educational Objectives

•  Upon completion of this course, participants should be able to:

•  Describe what makes a good MR biomarker.

•  Explain the Industrial perspective on using MR in clinical trials.

•  Discuss regulatory issues associated with using MR-based biomarkers in clinical trials.

•  Identify the critical aspects of successfully adding MR biomarkers to clinical trials.

•  Describe the challenges that have been encountered in using MR biomarkers in prior clinical trials.

Audience Description

This course is designed for graduate students, post-doctoral fellows, MR scientists, and clinicians who are interested in learning about the use of MR based biomarkers in clinical trials of new therapies. Attendees at all levels of MR research experience will find this course interesting.

13:30 MR as a Biomarker in Clinical Trials Jeffrey L. Evelhoch, Ph.D.
14:00 Regulatory Issues Associated with using new MR Jurgen J. Futterer, Ph.D..
Biomarkers and Diagnostic Agents  
14:30 Investigator Initiated Clinical Trials -  A Real Example Bonnie N. Joe, M.D., Ph.D 
15:00 Roundtable Discussion - Current Challenges and Possible Jeffrey L. Evelhoch, Jelle Barentsz,
Solutions Bonnie Joe, Michael V. Knopp 
  and John Kurhanewicz
15:30 Adjournment