Vessel Wall Imaging: Technical Advances

Stage Hall     10:30 - 12:30         Chairs: Deniz Bilecen and Zahi Adel Fayad


Prog #

10:30 434.

Molecular MRI of Thrombosis Using Novel Fibrin-Specific Contrast Agent: Initial Results in Humans at 3.0 T

Marcus Katoh1, 2, Andrea Wiethoff3, Roland Sparing4, Rolf W. Gunther4, Elmar Spuentrup4

1University Hospital Saarland, Homburg, Germany; 2University Hospital RWTH Aachen, Aachen, Germany; 3Philips Medical Systems, Netherlands; 4University Hospital RWTH Aachen, Germany

10:42 435.

p38 MAPK Inhibition Reduces Aortic Ultrasmall Superparamagnetic Iron Oxide Contrast Agent Uptake as

Assessed by MRI in an Atherosclerotic Mouse Model

Joanne B. Morris1, Alan R. Olzinski1, Roberta E. Bernard1, karpagam Aravindhan1, Robert N. Willette1, Beat M. Jucker1

1GlaxoSmithKline, King of Prussia, Pennsylvania, USA

10:54 436.

Iron Oxide Enhancing Atherosclerotic Plaque: Feasibility of White Marker Imaging Techniques

Carsten Warmuth1, J÷rg Schnorr2, 3, Susanne Wagner2, 3

1Siemens Medical Solutions, Erlangen, Germany; 2CharitÚ Universitńtsmedizin Berlin, Berlin, Germany; 3Ferropharm GmbH, Teltow, Germany

11:06 437.

Molecular Imaging of Macrophages in Atherosclerotic Plaques Using Bimodal PEG-Micelles

Willem J. M. Mulder1, 2, Gustav J. Strijkers2, Karen C. Briley-Saboe1, Juan C. Frias1, Juan Gilberto S. Aguinaldo1, Esad Vucic1, Klaas Nicolay2, Zahi A. Fayad1

1Mount Sinai School of Medicine, New York, USA; 2Eindhoven University of Technology, Eindhoven, Netherlands

11:18 438.

Combining Contrast Enhanced In Vivo and Ex Vivo MRI for Characterizing Vulnerable Plaques in a

Rabbit Model of Atherothrombosis

Alkystis Phinikaridou1, Kevin J. Hallock1, Ye Qiao1, James A. Hamilton1

1Boston University School of Medicine, Boston, Massachusetts, USA

11:30 439.

Gadolinium Mixed Micelles Containing Apolipoprotein E Derived Peptide for Atherosclerotic Plaque

Detection Through Interaction with Macrophages

Esad Vucic1, Karen Saebo1, Juan Gilbert Aguinaldo, Eik Leupold2, Edward A. Fisher3, Margitta Dathe4, Zahi A. Fayad1

1Mount Sinai School of Medicine, New York, New York, USA; 2Leipniz Institute of Molecular Pharmacology, Berlin; 3New York University School of Medicine, New York, New York, USA; 4Leipniz Institute of Molecular Pharmacology, Berlin, Germany

11:42 440.

Atherosclerotic Plaque Imaging with Ultra Short Echo Time (UTE) MRI

Sonia Nielles-Vallespin1, Sei Komatsu2, Peter Speier1, Kerstin V. Amann2, Stephan Achenbach2, Werner G. Daniel2, Edgar Mueller1

1Siemens AG Medical Solutions, Erlangen, Germany; 2University of Erlangen-Nuernberg, Erlangen, Germany

11:54 441.

Development of a Dark Blood MRI Protocol for Femoral Plaque Imaging

Venkatesh Mani1, Ioannis Koktzoglou2, Yiucho Chung3, Claudia Calcagno1, Daniel D. Samber1, Renate Jerecic3, Debiao Li2, Zahi A. Fayad1

1Mount Sinai School of Medicine, New York, New York, USA; 2Northwestern University, Chicago, Illinois, USA; 3Siemens Medical Solutions, Chicago, Illinois, USA

12:06 442.

Efficient Slow-Flowing Blood Suppression Technique in Atherosclerosis Imaging with Motion Sensitized

Driven Equilibrium (MSDE) TSE Sequence at 3T

Jinnan Wang1, Vasily Yarnykh1, Thomas Hatsukami2, Chun Yuan1

1University of Washington, Seattle, Washington, USA; 2VA Puget Sound Health Care System, Seattle, Washington, USA

12:18 443.

Delayed Hyperenhancement MR Coronary Vessel Wall Imaging in Patients with Stable and Unstable Coronary

Artery Disease

Tareq Ibrahim1, Antanas Jankauskas1, Markus Schwaiger1, Albert Schomig1, Warren J. Manning2, David Maintz3, RenÚ Michael Botnar1

1Technical University Munich, Munich, Germany; 2Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; 3University Munster, Munster, Germany