Pre-Clinical Imaging of Tumor Function and Structure

Dachgarten     16:00 - 18:00         Chairs: Arvind P. Pathak and Michal Neeman


Prog #

16:00 875.

EGF Receptor Expression Imaging Using Antibody-Conjugated Enzymes and a Paramagnetic Substrate

Alexei A. Bogdanov1, Manuel Querol1, Hye-Won Kang1, David G. Bennett2, Christopher Sotak2

1University of Massachusetts Medical School, Worcester, Massachusetts, USA; 2Worcester Polytechnic Institute, Worcester, Massachusetts, USA


16:12 876.

Detection of LacZ and Luciferase Double Gene Expression in Breast Cancer Xenograft by MRI and BLI

Weina Cui1, Li Liu1, Ralph Mason1

1UT Southwestern Medical Center, Dallas, Texas, USA

16:24 877.

Daidzein-BSA-GdDTPA/CyTE777 a Novel Contrast Material for Functional and Molecular Targeting of Ovarian Carcinoma Tumors

Helena Migalovich-Sheikhet1, Vyacheslav Kalchenko1, Fortune Kohen1, Michal Neeman1

1Weizmann Institute of Science, Rehovot, Israel

16:36 878.

DCE-MRI of Polyamidoamine Dendrimer-Nanoparticle Permeability in the RG-2 Rodent Malignant Glioma Model

Hemant Sarin1, Steve H. Fung1, Ariel Kanevsky1, Celeste Regino1, Tristan Barrett1, Ryan P. Lewis1, Martin W. Brechbiel1, Edward H. Oldfield1, John A. Butman1

1National Institutes of Health, Bethesda, Maryland, USA


16:48 879.

Quantitative Measurement of Cerebral Metastatic Tumor Burden of Breast Cancer Cells in a Nude Rat

Model Using T2* Map Histograms with Bioluminescence Imaging Correlation

Ho-Taek Song1, Bobbi K. Lewis1, Wei Liu1, E. Kay Jordan1, Brenda Klaunberg2, Daryl Despres2, Diane Palmieri3, Joseph Alan Frank1

1National Institute of Health, Bethesda, Maryland, USA; 2National Institute of Neurological Disorder and Stroke, Bethesda, Maryland, USA; 3National Cancer Institute, Bethesda, Maryland, USA


17:00 880.

Quantification of Liver Tumor Necrotic Fraction Using Diffusion-Weighted PROPELLER MRI

Jie Deng1, Joseph Young1, Sumeet Virmani1, Gayle E. Woloschak1, Guang-Yu Yang2, Reed A. Omary1, 3, Andrew C. Larson1, 3

1Northwestern Univeristy, Chicago, Illinois, USA; 2Northwestern University, Chicago, Illinois, USA; 3Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA


17:12 881.

Unique Structural Patterns in Rat Brain Tumors Revealed by High-Resolution Diffusion Tensor MRI

Jiangyang Zhang1, Peter C.M. van Zijl1, 2, John Laterra2, Amandeep Salhotra2, Bachchu Lal2, Susumu Mori1, 2, Jinyuan Zhou1

1Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 2Kennedy Krieger Institute, Baltimore, Maryland, USA


17:24 882.

Quantitative Description of Magnetization Transfer (MT) Asymmetry in Experimental Brain Tumors

Jun Hua1, 2, Peter C.M. van Zijl1, 2, Phillip Zhe Sun1, 2, Jinyuan Zhou1, 2

1Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 2KKI, Baltimore, Maryland, USA

17:36 883.

Water Population Changes in Glioma Gene Therapy as Measured by T and T - not available

Alejandra Sierra1, Shalom Michaeli2, Piia Valonen1, Heidi Gröhn1, 3, Michael Garwood2, Olli Gröhn1

1A. I. Virtanen Institute for Molecular Science, University of Kuopio, Kuopio, Finland; 2University of Minnesota Medical School, Minneapolis, Minnesota, USA; 3Kuopio University Hospital, Kuopio, Finland


17:48 884.

Characterization of a Prostate Cancer Xenograft in Orthotopic and Subcutaneous Sites

Marie-France Penet1, Arvind P. Pathak1, Venu Raman1, Paloma Ballesteros Garcia2, Dmitri Artemov1, Zaver M. Bhujwalla1

1The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 2IIB CSIC, Madrid, Spain