| Study Group |
| Psychiatric MR Spectroscopy and Imaging |
| Mini-Symposium |
| Separating the Wheat from the Chaff:
Pitfalls, Solutions and Controversies in MRS/MRSI Data
Analysis |
| |
| |
“In vivo
visualization of endogenous neural progenitor cells
(NPCs) is crucial to advance stem cell research and
will be essential to assure safety and efficacy of
neurogenesis based therapies. A distinct feature in
nuclear magnetic resonance (NMR) spectra, i.e. a
lipid signal at 1.28 ppm, was recently attributed
specifically to NPCs in vitro and to neurogenic
regions in vivo. Here, we demonstrate that, although
this 1.28 ppm biomarker is present in NPC cultures,
it is not specific for the latter. The 1.28 ppm
marker was also evident in mesenchymal stem cells
and in non-stem cell lines.” |
|
|
| |
- Ramm P, et al |
| |
Stem Cells,
Nov 6, 2008 [Epub ahead of print] |
|
| |
| Wednesday, 22 April 2009 |
| 19:30 - 2`:30 |
| Room 313A |
|
| |
| 19:30
|
Introduction and
Study Group Business |
| |
Chair: Dikoma C.
Shungu, Ph.D., Weill Medical College of Cornell
University, New York, NY, USA |
| |
|
| 19:45 |
Human Brain MRS
Data Analysis: Pitfalls and Solutions |
| |
Roland Kreis, Ph.D.,
University of Berne, Bern, Switzerland |
| |
|
| 20:20 |
Volumetric MRSI
Data Analysis Simplified |
| |
Andrew A. Maudsley,
Ph.D., University of Miami School of Medicine,
Miami, FL, USA |
| |
|
| 20:55 |
NMR Biomarker for
Neuronal Progenitor Cells: Is the 1.28 ppm Peak All
(or Even) Neurogenesis? |
| |
Paul Ramm, Doctoral
Student, University of Regensburg, Germany |
| |
|
|
|
|
|
|