Sunrise Course:
Quantitative Neuro-Anatomic and Functional Image Assessment
Organizers: Peter A. Bandettini, Ph.D. and Carlo Pierpaoli, M.D., Ph.D.
Skill Level: Advanced
Tuesday, 21 April 2009 - Friday, 24 April 2009
07:00 - 08:00

This four hour course will be presented by Ph.D. scientists covering the fundamental issues involved with extracting quantitative information from neuro-anatomic and functional MRI data. Principle topics to be covered are:
  • Quantitative assessment of white matter
  • Group anatomical comparisons
  • Calibration of activation-related and resting state fMRI.
  • The use of resting-state fMRI data for calibration of activation-related signal
The overall goals of this course are to instruct the MR physicist, neuroscience researcher, and clinician on the state of the art in methods for extracting and comparing quantitative anatomic and functional information from DTI data, standard anatomical data, and functional time series data.
Upon completion of this case based session, participants should be able to:
  • Assess the challenges and obstacles involved with quantitative assessment of anatomic and functional MRI data;
  • Describe the necessary steps to perform group comparisons of anatomic data;
  • List the neuronal, scanner-related, and physiological factors that influence the fluctuations in fMRI data;
  • Explain the neuronal, scanner-related, and physiological factors that influence the magnitude of the activation-induced fMRI signal change;
  • Describe the methods by which fMRI activation-related signal may be calibrated; and
  • List the methods by which fMRI resting state data can be filtered such that only neuronally related signal changes remain.

Tuesday, 21 April 2009
07:00 Quantitative Assessment of White Matter Andrew L. Alexander, Ph.D.
08:00 Adjournment  
Wednesday, 22 April 2009  
07:00 BOLD Activation Calibration Thomas Liu, Ph.D.
08:00 Adjournment  
Thursday, 23 April 2009  
07:00 Image Registration Daniel Rueckert, Ph.D.
07:30 Atlas Building and Statistical Group Analysis Guido Gerig, PhD.
08:00 Adjournment  
Friday, 24 April 2009  
07:00 Resting State BOLD Calibration Rasmus Birn, Ph.D.
08:00 Adjournment