Weekday Educational Course:
Rise and Fall of the Brain, Part 2: The Aging Brain
Organizers: Pia C. Maly Sundgren, M.D., Ph.D. and Mark A.van Buchem, M.D., Ph.D.
Skill Level: Intermediate - Advanced
Thursday, 23 April 2009
10:30 - 12:30

This two-hour course will begin with a focus on the variations of normal aging that can occur. We will explore the normal aging process, the underlying physiology of normal aging, and what can be seen in imaging of the elderly brain. We will provide a look at the underlying pathophysiology to pathological aging, and especially focus on abnormal aging, including Alzheimer’s disease and other forms of dementia. Also covered will be imaging techniques to use in a demented and sometimes uncooperative patient, and findings at imaging that can help to separate different forms of dementia based on the imaging pattern.

The course will continue with different pathologies such as small vessel disease and psychiatric diseases in the elderly patient. Speakers will discuss underlying pathophysiology to small vessel disease and imaging findings, different psychiatric diseases that can occur in the elderly population, imaging techniques/ modalities and imaging findings.
Upon completion of this case based session, participants should be able to:
  • Describe the basic phases of normal and pathological aging of the brain;
  • List the imaging findings seen in normal and abnormal brain aging;
  • Describe the basic MRI techniques necessary to obtain good quality in brain imaging of elderly patients;
  • Recognize the challenges, limitations, and pitfalls of current imaging techniques/modalities with respect to this patient population; and
  • Discuss future potential MR imaging techniques for the diagnosis, and treatment follow-up of some of the entities seen in the demented or psychiatric elderly patient.

Thursday, 23 April 2009
10:30 Normal Aging of the Brain Marco Essig, M.D., Ph.D.
11:00 Pathological Aging of the Brain Clifford R. Jack, Jr., M.D.
11:30 Small Vessel Disease Mark A. Van Buchem, M.D., Ph.D.
12:00 Psychiatric Diseases Anand Kumar, M.D.
12:30 Adjournment