Weekend Educational Course:
Diffusion Tensor MRI for the Clinician and the Neuroscientist:
From Experimental Design to Data Analysis
Organizer: Carlo Pierpaoli, M.D., Ph.D.
Skill Level: Intermediate
Saturday, 18 April 2009
14:00 - 18:00

This half day course is designed for scientists and clinicians starting to work in the field of diffusion tensor MRI who would like to have a roadmap for setting up their studies and interpreting their results. The first half of the course will cover the fundamentals of diffusion imaging acquisition, experimental design, data analysis, and clinical applications, with a lot of practical tips from experts in the field. The second part of the course will be dedicated to providing a comparative review of existing software packages for DT-MRI processing and analysis, and will include short presentations by their authors. A panel discussion will close the course. Participants should expect to improve their ability to design and carry out DT-MRI clinical studies and better describe potential artifacts and confounds.
Upon completion of this case based session, participants should be able to:
  • Decide what diffusion weighted imaging sequence is most appropriate for their studies;
  • Define an optimized experimental protocol for diffusion tensor MRI (DTI) given the time limit of their clinical scanning session;
  • Describe the various steps involved in a DTI processing pipeline;
  • Appraise the advantages and potential pitfalls of various DTI analysis strategies;
  • Being able to formulate biological interpretation of diffusion findings; and
  • Recognize software packages for DTI data processing and analysis that would be useful in their research

Saturday, 18 April 2009
14:00 How to Acquire Your Diffusion Images on a Clinical Scanner   Chunlei Liu, Ph.D.
14:20 How to Design Your Experiment and Process Your Data Derek K. Jones, Ph.D.
14:45 Strategies for Data Analysis Andrew L. Alexander, Ph.D.
15:10 Clinical Interpretation of DT-MRI Data Robert C. McKinstry, M.D.,Ph.D.
15:30 Break - Meet the Teachers  
16:00 Comparative Review of Available Software Packages Lindsay Walker, M.Sc., and M. Okan Irfanoglu
16:25 Poster Session with Presentations of Software Packages from Various Groups  
17:25 Panel discussion  
  "What You Always Wanted to Know About Diffusion MRI Processing, But Were Afraid to Ask"  
17:45 Adjournment - Meet the Teachers