Weekend Educational Course:
Clinical MR of Cancer
Organizers: Naranamangalam R. Jagannathan, Ph.D., and Daniel B. Vigneron, Ph.D.
Skill Level: Intermediate - Advanced
Sunday, 2 May 2010

This one-day course will focus on the role of clinical MR methods in the evaluation of cancer. It is designed for physicians (radiologists and oncologists) and for research scientists who wish to know the current state of the art and emerging MR techniques for clinical cancer investigations. It will cover the need for diagnosis, screening and development of various MR methods like imaging and spectroscopy in the evaluation of cancer of various organs;
current challenges in clinical diagnosis and management of the disease, including therapeutic selection, guidance and monitoring; key biological hallmarks of cancers that are assessable by MRI/MRS techniques that are ready for clinical translation; evaluation of the potential and the role of various MR imaging and spectroscopic techniques for various organ specific cancers and methods of biomarker qualification processes including the integration of multi-parametric information using statistical methods and bioinformatics.

Speakers will be both M.D.s and Ph.D.s and talks will give the participants a feel for the use of MR methodology for diagnosis, screening and the relevant biomarkers that can be used for diagnosis, the assessment of tumor aggressiveness, therapy response and resistance and be relevant to the development of novel anti-cancer therapeutics.

Upon completion of this course participants should be able to:
  • Describe the role and the challenges of various MR imaging and spectroscopic methods in cancer;
  • Identify problem areas in cancer screening, diagnosis and other related issues and how various MR methods can provide a solution;
  • Explain how MRI, MRS and MRSI biomarkers of cancer are used for diagnosis of cancer, for therapy planning and for therapeutic outcome assessment;
  • Describe the basis and evidence for MRI biomarkers that are ready for clinical translation; and
  • Use bioinformatics to integrate multi-parametric, multi-spectral imaging information.

08:30 Clinical Bottlenecks in Cancer Journeys Clare Tempany M.D.
09:00 Clinical Needs for Therapy Targeting Jelle O. Barentsz, M.D., Ph.D.
09:30 Response Assessments with Diffusion & Perfusion MRI Anwar R. Padhani, M.R.C.P., F.R.C.R.
10:00 Break  
  10:00 - 10:15 Meet the Teachers  
10:30 Diagnosis & Assessment Response of Cancer: Role for MRS N. R. Jagannathan, Ph.D.
11:00 Head and Neck Cancer: Meeting Challenges with MR Amita S. Dave, Ph.D.
11:30 Brain Tumors: Benefits of Advanced MRI/MRS  Sarah J. Nelson, Ph.D.
12:00 Break  
  12:00 - 12:15 - Meet the Teachers  
13:30 MRI Biomarkers in Breast Cancer Clinical Trials Nola Hylton, Ph.D.
14:00 The Difficult Liver with Cancer: Diagnosis with MRI Richard C. Semelka, M.D.
14:30 The Problematic Female Pelvis: Differential Diagnosis with MR Lindsay W. Turnbull M.D.
15:00 Break  
  15:00 - 15:15 Meet the Teachers  
15:30 Musculoskeletal Tumors and Bony Metastases: Can MR Do Better? Laura M. Fayad, M.D.
16:00 Prostate Cancer: Meeting Clinical Needs with Advanced MR John Kurhanewicz, Ph.D.
16:30 Hyperpolarized MR in Cancer: What It Tells Us about the Future Daniel B. Vigneron, Ph.D.
17:00  Automated Brain Cancer Diagnosis from the Tumor Metabolome John R. Griffiths M.B.B.S., D.Phil.
17:30 Adjournment  
  17:30 - 17:45 - Meet the Teachers  


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