Weekend Educational Course:
Diffusion & Perfusion II

An Updated Comparative View of MRI of Cerebral Perfusion
Organizer: Afonso C. Silva, Ph.D.
 
Skill Level: Intermediate - Advanced
Sunday, 2 May 2010

OVERVIEW
This half-day intermediate/advanced educational course will provide a comparative view of the two main methodologies used both in research and clinical practice today to measure cerebral perfusion: Arterial Spin Labeling and Dynamic Susceptibility Contrast (DSC-MRI). The speakers (M.D.’s and Ph.D.’s) will be our leading experts in MRI development and applications of ASL and DSC-MRI, and the main topics to be covered are:
  • Fundamentals of Arterial Spin Labeling and of DSC-MRI;
  • Applications of Arterial Spin Labeling and of DSC-MRI;
  • Limitations & Pitfalls of Arterial Spin Labeling and of DSC-MRI; and
  • The Future of Arterial Spin Labeling and of DSC-MRI.
 
EDUCATIONAL OBJECTIVES
Upon completion of this course participants should be able to:
  • List the major MRI techniques used to measure cerebral blood flow;
  • Describe the latest technical advances in arterial spin labeling (ASL) and dynamic susceptibility contrast (DSC) techniques to measure cerebral blood flow, and discuss their current limitations;
  • Describe the current status of methods to quantify perfusion and perfusion-related parameters in the healthy brain, and to compare the methodology to that required for robust quantification in the diseased brain;
  • Recognize the utility of MRI of brain perfusion to the diagnostics and treatment of cerebrovascular diseases, neurodegenerative diseases, and brain tumors, and to list its uses in pediatric applications; and
  • List non-conventional methods to measure brain function, understand and discuss their current limitations and predict their future applicability.

  Basic Principles  
13:30 Fundamentals of Arterial Spin Labeling Emmanuel L. Barbier, Ph.D.
13:55 Fundamentals of DSC-MRI Linda Knutsson, Ph.D.
     
  Applications  
14:20 Applications of Arterial Spin Labeling John A. Detre, M.D.
14:45 Applications of DSC-MRI Kathleen M. Schmainda, Ph.D.
15:10 Break  
  15:10 - 15:25 Meet the Teachers  
     
  Limitations & Pitfalls  
15:30   Limitations & Pitfalls of Arterial Spin Labeling Xavier G. Golay, Ph.D.
15:55 Limitations & Pitfalls of DSC-MRI Matthias J. P. Van Osch, Ph.D.
     
  The Future  
16:20 Future of Arterial Spin Labeling Eric C. Wong, M.D., Ph.D.
16:45 Future of DSC-MRI Leif Østergaard, M.D., Ph.D.
17:10 Adjournment  
  17:10 - 17:25 - Meet the Teachers  
     

 

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