Dynamic NMR Spectroscopy Study Group
Monday, 09 May 2011
18:45 - 20:55
Room 510

Topic: Advanced In vivo MRS Approaches for Studying Brain Under Resting & Working States
18:45 Business Meeting  
18:50 Presentations (15 minutes for talk and 5 minutes for discussion)  
  In vivo 13C MRS and Neurophysiological Methods for Studying Energy Demand of Working Brain States Fahmeed Hyder, Ph.D.
Yale University
New Haven, CT, USA
  In vivo 17O MRS for Assessing and Imaging Brain Oxygen Metabolism Gheorghe D. Mateescu, Ph.D.
Case Western Reserve University
Cleveland, OH, USA
  In vivo 1H MRS for Measuring Baseline GABA Versus Task-Evoked BOLD and its Correlation to MEG  C. John Evans, Ph.D.
Cardiff University
Cardiff, UK
  In vivo 31P MRS for Studying Brain ATP Energy and Budget Xiao-Hong Zhu, Ph.D.
University of Minnesota
Minneapolis, MN, USA
  In vivo Hyperpolarized 13C MRS Methods for Studying Brain Pyruvate Metabolism Ralph E. Hurd, Ph.D.
GE Healthcare
Menlo Park, CA, USA
20:30 Two junior talks selected from top posters related to in vivo brain MRS (10 minutes for talk and 2-3 minutes for discussion)
20:55 Adjourn    
These talks will help to address the following questions:

What unique information can be provided by each in vivo MRS approach?
What are pros and cons of each in vivo MRS approach?
What are challenges in quantifying dynamic NMR spectroscopy?
Can different in vivo MRS approaches provide complementary information?
How to choose an appropriate approach or multiple approaches for addressing a particular brain question of interest?
What are roles of in vivo MRS methods in understanding brain metabolism, neuroenergetics and function under resting and working states?