Molecular & Cellular Imaging
ORGANIZERS: Jeff W. M. Bulte, Ph.D. & Willem M. Mulder, Ph.D.
SKILL LEVEL: Intermediate to Advanced
Saturday, 7 May 2011

This one-day course will begin with a description of how contrast agents can be used to endow cell with MR-visible properties, and then how this enables tracking of stem cells and immune cells in various disease models. Different molecular probes will be described, of which some can provide contrast with other modalities. Some focus will be on combining these probes with therapeutic drugs in targeting of surface receptors. We will also cover issues involved with translating molecular imaging from small rodents to large animal models, and with clinical translation.
Upon completion of this course participants should be able to:
Describe the basic concepts that enable molecular and cellular imaging;
Describe the currently used contrast agents, molecular probes, and reporter genes;
Describe how molecular and cellular imaging is important to obtain a better understanding of the biological processes underlying certain diseases; and
Describe the steps that are necessary for clinical translation.

Click on to view the abstract pdf and click on to view the video presentation.
08:30 Nanomedicine & Molecular Imaging   John Frangioni, M.D., Ph.D.
09:00 DIACEST Agents & Sensors    Assaf A. Gilad, Ph.D.
09:30 PARACEST Agents & Sensors   Elena Vinogradov, Ph.D.
10:00 Break  
  10:00 -10:15 Meet the Teachers  
10:30 NON-CEST Biosensors   Angelique Louie, Ph.D.
11:00 siRNA Delivery & Imaging   Anna V. Moore, Ph.D.
11:30 Advances in Preclinical Tracking   Paula J. Foster, Ph.D.
12:00 Break  
  12:00 - 12:15 Meet the Teachers  
13:30 MRI Reporter Genes   Glenn A. Walter, Ph.D.
14:00 MR Imaging of Allograft Rejection   Yijen Lin Wu, Ph.D.
14:30 Cerebral Gene Transcript Quantification In Vivo using MRI   Philip Liu, Ph.D.
15:00 Break  
  15:00 - 15:15 Meet the Teachers  
15:30 Lipoprotein-Derived Multimodal Nanoparticles   David P. Cormode, Ph.D.
16:00 Clinical Cell Tracking Using PET   Shahriar Yaghoubi, Ph.D.
16:30 Clinical Cell Tracking Using MRI   Piotr Walczak, M.D.
17:00 Adjournment  
  17:00-17:15 Meet the Teachers