Preclinical MR of Cancer – Addressing Clinical Needs
ORGANIZERS: Kevin M. Brindle, D.Phil. & Sabrina M. Ronen, Ph.D.
SKILL LEVEL: Basic-Intermediate
Saturday, 5 May 2012

This one-day course will focus on cancer in preclinical models including MR imaging, MR spectroscopy and MR spectroscopic imaging studies. The first part of the course will be geared to beginners. It will describe tumor physiology and metabolism and the basic ‘how to’ aspects of a range of preclinical methods in different types of models. The second part of the course will be geared to beginners/intermediates. It will describe the application of the methods outlined in part one to preclinical cancer research. It will cover well-established applications and emerging state-of-the-art approaches. Thus it is anticipated that the second part of course will prepare participants for new cancer-related MR applications that may emerge in the next few years.
Upon completion of this course participants should be able to:
Describe basic tumor physiology and metabolism;
Implement basic MRI, MRS and MRSI technologies in preclinical cancer research studies including studies of cells, tissue samples and animal models;
Describe the principal applications of basic MRI, MRS and MRSI technologies in preclinical cancer research studies; and
Explain how MRI, MRS and MRSI biomarkers of cancer are used for diagnosis of cancer, for therapy planning and for assessing outcome of therapy.
This course is designed for radiologists, oncologists and research scientists with an interest in oncology. It will be helpful to those with less experience, as well as those with a moderate amount of experience in the field.


Click on to view the abstract pdf. Click on to view the recorded presentation.

  Moderators: Kevin M. Brindle, D.Phil. & Sabrina M. Ronen, Ph.D.
08:30 Tumor Metabolism Kevin M. Brindle, D.Phil.
09:00 Tumor Physiology Hagit Dafni, Ph.D.
09:30 Tumor 'Omics' John R. Griffiths, D.Phil., M.B.B.S.
10:00 Break - Meet the Teachers  
10:30 How to Study Cancer Cell Models E. Jim Delikatny, Ph.D.
11:00 How to Perform MRI/MRS in Animal Models Chantal Rémy, Ph.D.
11:30 Tumor Lipid Metabolism Franca Podo, D.Sc.
12:00 Break  
  12:00-12:15 Meet the Teachers  
13:30 Tumor Energy Metabolism Sebastián Cerdán, Ph.D.
14:00 pH in Cancer Robert J. Gillies, Ph.D.
14:30 Molecular Imaging in Cancer Dmitri Artemov, Ph.D.
15:00 Break - Meet the Teachers  
15:30 Tumor Vasculature Rinat Abramovitch, Ph.D.
16:00 Tumor Cellularity Charles S. Springer, Jr., Ph.D.
16:30 Detecting Specific Drug Responses Sabrina M. Ronen, Ph.D.
17:00 Adjournment  
  17:00-17:15 Meet the Teachers