MR Properties of Tissue
ORGANIZERS: Mina Kim, Ph.D. & Claudia A. Wheeler-Kingshott, Ph.D.
SKILL LEVEL: Basic-Intermediate
Saturday, 5 May 2012

This half-day course will encompass a relatively non-technical, yet scientifically rigorous, overview of MR properties of tissues. Attendees will learn about contrast mechanisms of MR signal (T1/T2 relaxation times, susceptibility/T2* and magnetization transfer) and the effect of exchange and compartmentalization, and the overall future direction. We will provide a wide overview of the biophysical sources of contrast mechanisms and how to exploit them for quantitative MRI applications. The course will conclude with an exploration of what the future holds.
Upon completion of this course participants should be able to:
Explain the methods to acquire data with contrast coming from different relaxation times;
Identify the methods for enhancing the effects linked to different susceptibility properties of tissue;
Identify methods for measuring magnetization transfer effects linked to macromolecules and chemical exchange properties of tissue;
Describe the biophysical sources that influence the various contrasts, with particular attention to exchange and compartmentalization; and
Recognize potential future clinical applications of these techniques as technology improves.
This course is designed for scientists and clinicians who are starting to work in the field of quantitative MRI and would like to gain a scientific and technical understanding of available techniques. The course assumes basic previous knowledge of MRI, but not necessarily familiarity with relaxometry, susceptibility and magnetization transfer mechanisms.


Click on to view the abstract pdf. Click on to view the recorded presentation.

  Moderators: Mina Kim, Ph.D. & Claudia A. Wheeler-Kingshott, Ph.D.
14:00 Contributions to Relaxation Times & Diffusion Gareth J. Barker, Ph.D.
14:30 T1 Properties of Healthy & Diseased Tissue Penny Anne Gowland, Ph.D.
15:00 T2 Properties of Healthy & Diseased Tissue Robert V. Mulkern, Jr., Ph.D.
15:30 Break - Meet the Teachers  
16:00 Susceptibility & T2*Contrast Mechanism Chunlei Liu, Ph.D.
16:30 Measuring Exchange & Compartmentalization Itamar Ronen, Ph.D.
17:00 Magnetization Transfer Properties of Tissue Peter van Zijl, Ph.D.
17:30 What Does the Future Hold? John C. Gore, Ph.D.
18:00 Adjournment  
  18:00-18:15 Meet the Teachers