ISMRM 21st Annual Meeting & Exhibition 20-26 April 2013 Salt Lake City, Utah, USA

Pre-Clinical MR of Cancer
SKILL LEVEL: Intermediate to Advanced
ORGANIZER: E. Jim Delikatny, Ph.D.
Saturday, 20 April 2013
This one-day course will focus on cancer in preclinical models including MR imaging, MR spectroscopy and MR spectroscopic imaging studies. The first part of the course will be geared to beginners. It will describe tumor physiology and metabolism and the basic 'how to' aspects of a range of preclinical methods in different types of models. The second part of the course will be geared to beginners/ intermediates. It will describe the application of the methods outlined in part one to preclinical cancer research. It will cover well-established applications and emerging state-of-the-art approaches. Thus it is anticipated that the second part of course will prepare participants for new cancer-related MR applications that may emerge in the next few years.
This course is designed for radiologists, oncologists and research scientists with an interest in oncology. It will be helpful to those with less experience, as well as those with a moderate amount of experience in the field.

Upon completion of this course, participants should be able to:

  • Describe basic tumor physiology and metabolism;
  • Implement basic MRI, MRS and MRSI technologies in preclinical cancer research studies including studies of cells, tissue samples and animal models;
  • Describe the principal applications of basic MRI, MRS and MRSI technologies in preclinical cancer research studies; and
  • Explain how MRI, MRS and MRSI biomarkers of cancer are used for diagnosis of cancer, for therapy planning and for assessing outcome of therapy.


Moderators: E. Jim Delikatny, Ph.D. & Kristine Glunde, Ph.D.

08:30 Tumor Metabolism Kevin M. Brindle, Ph.D.
09:00 Tumor Physiology Michal Neeman, Ph.D.
09:30 Tumor 'Omics John R. Griffiths, D.Phil, F.R.C.P.
10:00     Break - Meet the Teachers  
10:30 MR in Cancer Cell Models Franca Podo, D.Sc.
11:00 MRI/MRS in Animal Models Harish Poptani, Ph.D.
11:30 Tumor Lipid Metabolism Kristine Glunde, Ph.D.
12:00     Break  
      12:00-12:15 Meet the Teachers  
13:30 Tumor Energy Metabolism Klaas Nicolay, Ph.D.
14:00 pH in Cancer Robert J. Gillies, Ph.D.
14:30 Molecular Imaging in Cancer Dmitri Artemov, Ph.D.
15:00     Break - Meet the Teachers  
15:30 Tumor Vasculature & Perfusion Charles S. Springer, Ph.D.
16:00 Novel Contrast: CEST, Multinuclear Michael T. McMahon, Ph.D.
16:30 Cancer Treatment Response Sabrina M. Ronen, Ph.D.
17:00     Adjournment  
      17:00-17:15 Meet the Teachers