Joint Annual Meeting ISMRM-ESMRMB 2014 10-16 May 2014 Milan, Italy

SKILL LEVEL: Intermediate
ORGANIZERS: David L. Buckley, Ph.D. & Eric C. Wong, M.D., Ph.D.
Sunday, 11 May 2014 (07:40 - 12:00)
This half-day, intermediate course is designed for scientists and clinicians who want to learn about MR imaging of perfusion and related parameters. The course will begin with a description of the physiology of perfusion, followed by the theory and methodology of the main classes of perfusion imaging techniques (dynamic susceptibility contrast MRI, dynamic contrast enhanced MRI, and arterial spin labeling). Imaging of blood oxygenation, which is a emerging field, will be highlighted with a dedicated presentation. Finally, an overview of applications of perfusion imaging methods will be presented, with particular attention to which methods are most appropriate for particular applications.
This course is aimed at basic research scientists and clinicians. It is expected to provide attendees with an understanding of fundamental as well as practical aspects of perfusion MRI, and a solid background upon which to base decisions about choice of perfusion imaging methods for their own applications.

As a result of attending this course, participants should be able to:

  • Define and understand the relationships between perfusion and related parameters such as transit times, blood volume, permeability, and oxygenation;
  • Describe the basic principles of arterial spin labeling, dynamic susceptibility contrast, and dynamic contrast enhancement;
  • Identify which parameters each of the above methods are inherently sensitive to and why;
  • Identify which parameters each of the above methods are inherently insensitive to and why;
  • Describe the key issues in the extraction of physiological parameters from ASL, DSC, and DCE data;
  • Identify applications for which each of the above methods are well suited; and
  • Contrast new methods with current methods for measurement of blood oxygenation.


Moderators: David L. Buckley, Ph.D. & Eric C. Wong, M.D., Ph.D.

07:40 What is Perfusion & How is it Measured? Richard B. Buxton, Ph.D.
08:20 Dynamic Susceptibility Contrast Matthias J. P. van Osch, Ph.D.
09:00 Dynamic Contrast Enhanced Steven P. Sourbron, Ph.D.
09:40     Break - Meet the Teachers  
10:00 Arterial Spin Labeling Xavier G. Golay, Ph.D.
10:40 MR Imaging of Cerebral Oxygen Extraction & Metabolism Divya S. Bolar, M.D., Ph.D.
11:20 Applications of Perfusion MRI Greg Zaharchuk, M.D., Ph.D.
12:00     Adjournment  
      12:00 - 12:15 - Meet the Teachers