ISMRM 24th Annual Meeting & Exhibition 07-13 May 2016 Singapore

Sunrise Educational Session: Ultra-High Field Cardiovascular MRI

Skill Level: Intermediate to Advanced

Organizers: Harald Kramer, M.D. & Jeanette Schulz-Menger, M.D.

Tuesday 10 May 2016

This session will provide an update on cardiovascular MRI at ultra-high field. Presentations will discuss the current state-of-the-art in vascular imaging, the use of 31P spectroscopy for the evaluation of cardiac metabolism and the challenges of performing morphological cardiac imaging at 7T.

Target Audience
Scientists, engineers and clinicians with a good understanding of the principles of cardiovascular MRI who wish to understand some of the challenges and opportunities of cardiovascular MRI and MRS at 7T.

Educational Objectives
Upon completion of this course, participants should be able to:

  • Assess the value of 7T for vascular imaging;
  • Describe how cardiac metabolism can be investigated using 31P MRS at 7T; and
  • Explain the challenges of 7T in morphological cardiac imaging.

Moderators: Harald Kramer, Jeanette Schulz-Menger
Vascular MR at 7T - Permission Withheld
Harald H. Quick1
1Erwin L. Hahn Institute for MR Imaging, University of Duisburg-Essen, Essen, Germany
The high sensitivity inherent to ultra-high field (UHF) MR imaging can be used to achieve 7T MRA data of the intracranial vasculature and pathologies with unsurpassed high spatial resolution and vessel detail. The translation from intracranial UHF MRA to body MRA applications, however, is currently limited by numerous technical challenges including radiofrequency coils and methods for signal homogenization. Initial studies providing encouraging first results of 7T body and peripheral MRA on patients have demonstrated that these hurdles can be overcome. This can be seen as a first step to further assess the clinical potential of vascular MR at 7T.

Cardiac Spectroscopy at 7T
Christopher Rodgers
Magnetic resonance spectroscopy (MRS)1-4 is a method for non-invasively probing metabolism. In the heart, phosphorus 31P MRS has proved particularly valuable because it probes the creatine-kinase system which buffers and actively transports ATP from its site of generation in the mitochondria to its site of utilisation in the myofibrils, where it drives contractile work, pumps blood around the body, and sustains life. In most heart diseases, the concentrations and/or the rates of interconversion of 31P metabolites are altered. Spectroscopy benefits from ultra-high fields in two main ways: (i) the signal-to-noise ratio for a fixed scan time increases approximately proportional to B0; and (ii) the frequency separation between the peaks from different metabolites increases proportional to B0 which makes robust spectral fitting easier. This session reviews the first human cardiac spectroscopy studies at 7T.

07:32 Morphological Cardiac MR at 7T
Thoralf Niendorf1
1Max-Delbrueck Ctr for Molecular Medicine, Germany
Adjournment & Meet the Teachers

The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for
Continuing Medical Education to provide continuing medical education for physicians.