ISMRM 24th Annual Meeting & Exhibition 07-13 May 2016 Singapore

Sunrise Educational Session: Cardiovascular Image Processing

Skill Level: Intermediate to Advanced

Organizers: Daniel Ennis, Ph.D. & Martin J. Graves, Ph.D.

Wednesday 11 May 2016

This session will describe the various image processing methods used to extract quantitative information from cardiac MRI images. The speakers will explain the approaches used for the analysis and display of global and regional ventricular function, the requirements for quantitative analysis of myocardial perfusion images and the methods used to extract quantitative data from phase contrast techniques.

Target Audience
Scientists, engineers and clinicians with a good understanding of cardiovascular MRI who wish to understand the image processing algorithms and methods used for the quantitative analysis of functional cardiac images, myocardial perfusion studies and 2D and 4D phase contrast data.

Educational Objectives
Upon completion of this course, participants should be able to:

  • Describe the methods used for the quantitative analysis of ventricular function;
  • Assess the algorithms used for the quantification of myocardial perfusion; and
  • Discuss the techniques used for quantification of flow from 2D and 4D phase contrast methods.

Moderators: Daniel Ennis, Martin Graves
Functional Analysis
Daniel Ennis1 and Rob J van der Geest2
1UCLA, 2Dept. Radiology, Leiden University Medical Center, Leiden, Netherlands
Assessment of LV dimensions and global systolic function is a key element of every CMR examination. Accurate and reproducible quantification is highly important and requires an appropriate MR acquisition protocol as well as careful use of image analysis methods.


Perfusion Quantification
Michael Jerosch-Herold1
1Radiology, Brigham & Women's Hospital, Boston, MA, United States
This presentation focuses on the quantification of myocardial perfusion using rapid dynamic imaging during the first pass of contrast bolus through the heart.  The approaches which can be used for quantifying myocardial blood flow from the observed contrast enhancement can be broadly divided into two categories, which we label here as model-based and model-independent. For model-based approaches one specifies the functional spaces in myocardial tissue, how tracer moves through these spaces, and how it traverses permeable barriers between the spaces.  Model-independent analysis means that one foregoes specifying a model of the tissue structure. Model-independent analysis is based on the central volume principle.

2D/4D Flow Quantification
Alejandro Roldan-Alzate
This presentation will review the data acquisition, post processing, and blood flow quantification using standard 2D PC and 4D Flow MRI. Sources of error for the blood flow measurements will also be analyzed.

Adjournment & Meet the Teachers

The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for
Continuing Medical Education to provide continuing medical education for physicians.