ISMRM 24th Annual Meeting & Exhibition 07-13 May 2016 Singapore

Sunrise Educational Session: Controversies in Diffusion & Functional MRI

Skill Level: Intermediate to Advanced

Organizers: Daniel C. Alexander, Ph.D., Jay J. Pillai, M.D. & Jonathan R. Polimeni, Ph.D.

Wednesday 11 May 2016

This session will survey several current controversial topics in diffusion and functional MRI, including those affecting assessment of tissue microstructure, applications to presurgical mapping, and new approaches to measuring and analyzing functional MRI signals.

Target Audience
Cognitive neuroscientists, neuroradiologists and other clinicians as well as imaging scientists who currently utilize functional or diffusion MRI for basic science or for presurgical planning. This course assumes basic knowledge of functional and diffusion MRI and a working knowledge of basic analysis methods.

Educational Objectives
Upon completion of this course, participants should be able to:

  • Explain the limits of diffusion MRI sensitivity and potential benefits of combining with other modalities;
  • Understand the difficulties of multimodal acquisition and modelling and why the benefits of multimodality are unclear for microstructure imaging;
  • Recognize the advantages and limitations of different diffusion tractography approaches for presurgical mapping;
  • Understand the promise as well as the limitations of resting state BOLD with respect to presurgical mapping;
  • Implement a model-free analysis of task-driven fMRI data and evaluate the suitability of a canonical hemodynamic response model; and
  • Evaluate the many techniques available for measuring neuronal activity without utilizing the hemodynamic response, including neuronal current imaging.

Moderator: Jay J. Pillai
      Controversies in Presurgical Mapping  
Ultra-Fast fMRI of Task & Rest
Vesa J. Kiviniemi1
1OFNI/Oulu University Hospital
Understaning of brain activity during both controlled task and spontaneous resting activity has increased markedly over the years. The network structures supporting both forms of function are virtually identical. Thus also pre-surgical fMRI can be done both ways with nearly identical accuracy; task activation with exact focus on spesific activity and resting state without control but less dependent on patient complience. Recent ultra-fast scanning methods enable more in depth analysis of brain function and physiology presumably at the individual level.

Advanced Diffusion vs DTI Tractography for Surgical Planning
Alberto Bizzi1
1Neuroradiology, Fondazione IRCCS Istituto Neurologico Besta, Milano, Italy
Adjournment & Meet the Teachers

The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for
Continuing Medical Education to provide continuing medical education for physicians.