ISMRM 24th Annual Meeting & Exhibition • 07-13 May 2016 • Singapore

Educational Session: All About Bones

Skill Level: Intermediate

Organizers: Jenny T. Bencardino, M.D., Eric Y. Chang, M.D., Christine Chung, M.D., Ravinder R. Regatte, Ph.D., Philip Robinson, M.D. & Siegfried Trattnig, M.D.

Thursday 12 May 2016

To review various aspects of imaging bone, trabecular organization, as well as marrow cellular and lipid components will be will be presented by a panel of experts, with lectures ranging from sequence development to clinical applications. It is intended to “bridge the gap” between basic research and patient care.

Target Audience
M.D.'s and Ph.D.'s

Educational Objectives
Upon completion of this course, participants should be able to:

  • Apply various MRI techniques to assess bone architecture and composition in clinical practice and research studies;
  • Recognize MR imaging patterns of bone marrow edema and osteonecrosis and distinguish them from infiltrating marrow disorders; and
  • Refine or apply new MRI techniques to assess bone architecture and composition in clinical practice and osteoporosis research studies.

Moderators: Feliks Kogan, Mary Manhard
Update on Imaging Techniques for Evaluation of Bone
Chamith Rajapakse1
1University of Pennsylvania
Millions of people worldwide suffer from bone diseases, predisposing them to fractures and related comorbidities that have devastating consequences. Imaging plays an important role in fracture risk assessment, diagnosis, staging, and treatment monitoring of patients with bone diseases. Flexibility of MRI has paved the way for non-invasive assessment of bone quality at multiple levels, including trabecular and cortical bone. This talk will provide an overview of emerging MR-based approaches for quantifying bone quality in human subjects.

Bone Marrow Edema & Osteonecrosis
Christopher J. Hanrahan1
1Department of Radiology and Imaging Sciences, University of Utah School of Medicine, Salt Lake City, UT, United States
This presentation will review the MR appearance of normal maturation of bone marrow, osteonecrosis, and features that will aid in determining the underlying cause of bone marrow edema.

Imaging of Bone in Osteoporosis and Osteoarthritis
Sharmila Majumdar
Bone changes are important in several conditions such as osteoporosis and osteoarthritis. Imaging methods for understanding bone changes, and their relationship to fracture status in osteoporosis and cartilage changes in osteoarthritis will be covered.

Evaluation of Bone Metabolism & Remodeling with PET/MR
Feliks Kogan1
1Stanford University
18F-Sodium Fluoride (NaF) is a long recognized bone-seeking agent that is sensitive to bony metabolism and remodeling. New hybrid PET-MRI systems offer to combine the benefits of MRI high-resolution morphologic imaging with functional information from PET for simultaneous, sensitive and quantitative assessment of bone quality and remodeling. This presents an opportunity to not only assess bony activity, but to also to characterize established quantitative and qualitative MRI metrics of bone health.

Adjournment & Meet the Teachers

The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for
Continuing Medical Education to provide continuing medical education for physicians.