ISMRM 24th Annual Meeting & Exhibition • 07-13 May 2016 • Singapore

Educational Session: Clinical Implications of the MRI Phenotype in Oncology

Skill Level: Intermediate

Organizers: Ivan Pedrosa, M.D., Lorenzo Mannelli, M.D., Ph.D., Scott B. Reeder, M.D., Ph.D. & Edwin J.R. van Beek, M.D., Ph.D., M.Ed., FRCR

Wednesday 11 May 2016

This two-hour course focuses on the value of tumor characterization with MRI, or MRI phenotype, for the assessment of common neoplasms in the abdomen and pelvis. Emphasis will be made on correlations between MRI findings and histopathologic features in these tumors. The impact of specific MRI findings on treatment decisions and their prognostic implications will be presented. MRI protocols to facilitate tumor characterization in clinical practice will be discussed.

Target Audience
This course is aimed at radiologists and imaging scientists who wish to learn about the clinical utility of the MRI phenotype for the characterization of abdominopelvic neoplasms and the importance of incorporating tumor characteristics for management decisions in routine clinical practice.

Educational Objectives
Upon completion of this course, participants should be able to:

  • Convey the characterisitc of cystic pancreatic neoplasms that increase the risk of invasive malignancy;
  • Understand the MRI features in hepatocellular carcinoma that predict aggresive behavior and response to different local and systemic therapies;
  • Illustrate the implications of the MRI phenotype in the prognosis of renal cell carcinoma; and
  • Describe the MRI features that affect the likelihood of local and distant recurrence in rectal cancer.

Moderators: Richard Do, Takeshi Yokoo
Approach to Cystic Pancreatic Neoplasms using MRI Phenotype
Aarti Sekhar1
1Radiology, Emory University, Atlanta, GA, United States
Approach to Cystic Pancreatic Neoplasms using MRI Phenotype.  Radiologists are only approximately 60% accurate in providing the correct diagnosis of cystic pancreatic neoplasms pre-operatively.  This image rich talk will cover the typical and atypical MRI characteristics for the seven most common cystic pancreatic neoplasms (IPMN, mucinous cystic neoplasm, serous cystadenoma, pseudocyst, cystic neuroendocrine tumor, necrotic adenocarcinoma and solid pseudopapillary tumors), and emphasize distinct MRI features that can help narrow the differential diagnosis.  Useful clinical information, such as patient history and demographics will be covered.  Common pitfalls will also be discussed.  

Hepatocellular Carcinoma - Permission Withheld
Mi-Suk Park1
1Diagnostic Radiology, Severance hospital/Yonsei University, Seoul, Korea, Republic of
Several studies reveal a large number of MRI phenotypes related to the biologic behavior of hepatocellular carcinoma (HCC). Hemodynamic change-related, peri-tumoral change-related, hepatocyte-related, and diffusion-related phenotypes. In this talk, I will touch on various MRI features of HCC and their implications for the diagnosis and prognosis as imaging biomarkers.

Renal Cell Carcinoma
Mike Notohamiprodjo1
1Universitätsklinikum Tübingen
Rectal Cancer: Clinical Implications of the MRI Phenotype in Oncology
Stephanie Nougaret1
1CHU Montpellier
 1)   To propose a step-by-step approach for standardized MRI staging of pre-treatment rectal carcinoma using the mnemonic "DISTANCE".

2)   To become familiar with the different treatment strategies and organ preservation in rectal cancer.

3)    To know the performance of modern MRI for the prediction of treatment response.

4)   To learn how to evaluate response after chemoradiotherapy and understand how MRI findings may alter surgical approach and affect the likelihood of local and distant recurrence.    

Adjournment & Meet the Teachers

The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for
Continuing Medical Education to provide continuing medical education for physicians.