ISMRM 24th Annual Meeting & Exhibition • 07-13 May 2016 • Singapore

Weekend Educational Course: Neuro 1

Skill Level: Intermediate

Organizers: Jonathan H. Gillard, M.D., FRCR, MBA & Jennifer A. McNab, Ph.D.

Saturday 07 May 2016

This course will explore the uses of MRI in the treatment of acute stroke, tumours of the brain, head and neck and neonate abnormalities.

Target Audience
Neuroradiologists, clinical neurospecialists and neuroimaging researchers.

Educational Objectives
Upon completion of this course, participants should be able to:

  • Identify appropriate imaging methods to select patients for stroke therapy;
  • Distinguish the most appropriate imaging techniques for evaluating stroke, tumours and neonate abnormalities and recognise the rationale for using alternative imaging strategies;
  • Discuss appropriate imaging methods to investigate intracranial, parenchymal hemorrahge and evaluate their clinical benefit; and
  • Identify appropriate imaging methods to investigate head and neck cancer and evaluate their clinical benefit.

      Stroke Triage  
      Moderators: Audrey Fan, Henk-Jan Mutsaerts  
Stroke Triage: The Radiologist's Perspective
Patricia Desmond1
1University of Melbourne, Royal Melbourne Hospital
Acute ischemic stroke is a heterogeneous disease, with major stroke caused by proximal artery occlusions representing the stroke subtype with the most devastating outcomes.  With the recent success of the  endovascular clot retrieval  trials for major stroke, the primary role of the radiologist to identify the patients  suitable for treatment rapidly and accurately. The most common way to get this information is with non contrast CT, and CT angiography. In present clinical practice, time is dominant (<6hr) over physiology for decisions related to implementing therapy. There is evidence from the recent trials that it may be possible to extend the  selection criteria to include a larger group of patients that will still benefit from IA therapy. However, this will require clinical trials to demonstrate that  advanced imaging techniques to select these patients for treatment, leads to improved  outcomes.

Stroke Triage: The Physicist's Perspective
Manus Donahue1
1Vanderbilt University Medical Center
The overall goal of this presentation is to provide a summary of the major unmet clinical needs in stroke imaging and management from a physicist’s perspective. Stroke imaging can broadly be considered in terms of (i) characterizing hemodynamic compensation mechanisms with the goal of stratifying treatments to prevent stroke, (ii) identifying viable tissue at risk for infarction in the setting of acute stroke, and (iii) evaluating chronic, post-stroke hemodynamic and neurochemical processes that may portend functional recovery. 

Panel Discussion
Break & Meet the Teachers
      Tumor Tutorial  
      Moderator: Stephen Price, Yi-Fen Yen  
Tumor Tutorial: The Radiologist's Perspective - Permission Withheld
Pia Maly Sundgren1
1Radiology, Lund University, Lund, Sweden
Different aspect of the problems facing the radiologist when evaluating brain tumours and the possible support of advance MR imaging methods as well as new imaging biomarkers will be presented..

Tumor Tutorial: The Physicist's Perspective - Permission Withheld
Peter Barker
This presentation will review selected new techniques and applications for the imaging of human brain tumors, from the point of view of the MR physicist. A particular emphasis will be on metabolic MR neuroimaging techniques, including chemical exchange saturation transfer methods. The challenges involved in developing a new MR imaging technique for clinical use in humans will be considered.

Tumor Tutorial: The Neuro-Oncologist's Perspective
Tham Chee Kian1
1Singapore Health
Break & Meet the Teachers
      Head & Neck  
      Moderators: Priti Balchandani, Jennifer McNab  
Head & Neck: The Surgeon's Perspective
Thomas Loh Kwok Seng1
1National University Hospital
Head & Neck: The Radiologist's Perspective
Eric Ting1
1National University of Singapore
Head and Neck: MRI of Laryngeal and Hypopharyngeal Cancers - Permission Withheld
Julian Goh1
1Tan Tock Seng Hospital
Laryngeal and hypopharyngeal cancers have traditionally been staged using CT. These areas have previously been difficult to assess with MRI, given the small structures and prohibitive imaging times. However, with improvements in both hardware and software, thin slice MR images of these areas can now be performed within a reasonable amount of time, with superior soft tissue resolution compared to CT. This allows identification of important features that affect management decisions and help direct treatment, even in recurrent disease. MRI has now become a powerful tool in the management of these neoplasms. 

Break & Meet the Teachers
      Moderator: Robert Mckinstry  
Neonate: The Neonatologist's Perspective "Preterm newborns: How imaging contributes to the understanding of the preterm infants neurodevelopmental outcome"
Petra Hüppi
This educational presentation will summarize the imaging tools to study the brain of preterm infants, detect brain injury and predict neurodevelopment outcome

Neonate: The Physicist's Perspective
Simon Warfield1
1Radiology, Harvard Medical School, Boston, MA, United States
Term newborns: How imaging contributes to the understanding of the development of brain injury after birth asphyxia
Pia Wintermark1
1McGill University
Term newborns are at risk to develop brain injury. Magnetic resonance imaging has permitted to better understand how brain injury develops despite standard available treatments. The use of magnetic resonance imaging has also given clues of which newborns would benefit from additional treatments, and indications for possible alternative treatments. However, magnetic resonance imaging in these newborns remains challenging, and must imperatively be improved to allow further detection and treatment. This education session will cover the advantages and limitations of magnetic resonance imaging in term newborns.

Adjournment & Meet the Teachers

The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for
Continuing Medical Education to provide continuing medical education for physicians.