ISMRM 25th Annual Meeting & Exhibition • 22-27 April 2017 • Honolulu, HI, USA

Sunrise Educational Session: Contrast Mechanisms in MSK Imaging
Sunrise Session

ORGANIZERS: Jenny T. Bencardino, M.D., Eric Y. Chang, M.D., Christine Chung, M.D. & Philip Robinson, M.D.

Monday, 24 April 2017
Room 312  07:00 - 07:50 Moderators: Graeme Bydder, Ives Levesque

Skill Level: Advanced

Slack Channel: #e_msk
Session Number: SM02

This course will provide an in-depth discussion on contrast mechanisms in musculoskeletal MR imaging. Technical concepts underpinning the large variety of contrast mechanisms that are well established or emerging will be discussed. Clinical applicability for imaging normal and abnormal tissues and conditions will be featured.

Target Audience
Radiologists and Physicists

Educational Objectives
Upon completion of this course, participants should be able to:

-Describe the mechanism of three endogenous contrasts used in clinical imaging;
-Identify the effects of tissue anisotropy on relaxation properties; and
-Apply understanding of mechanism of image contrast in musculoskeletal MRI to clinical and translational research applications.

Magnetization Transfer: Applications in MSK imaging
Ives Levesque
Magnetization transfer (MT) is a distinct endogenous mechanism that impacts MR signal and image contrast. MT is sensitive to the MRI-invisible component of biological tissue. In this presentation, we will review the physics, measurement techniques, and selected research findings from MT-MRI in the musculoskeletal system, in particular with relevance to collagen-rich tissues.

Fat Water Separation: Applications in MSK imaging
Johan Berglund
Dixon’s fat/water separation method offers fat suppression based on chemical shift, insensitive to main field inhomogeneity, which is desirable in musculoskeletal MRI when imaging off-center, at anatomical sites with strong patient induced field inhomogeneity, or near metallic implants. A single acquisition additionally yields non fat suppressed and fat only-images, providing additional information that can potentially replace conventional images, in particular imaging both with and without spectral fat saturation. The method is compatible with both spin echo and gradient echo sequences with various contrast weighting. The prolonged acquisition time comes with increased SNR, providing capacity for compensation using other acceleration techniques.


The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for
Continuing Medical Education to provide continuing medical education for physicians.