ISMRM 25th Annual Meeting & Exhibition 22-27 April 2017 Honolulu, HI, USA

Sunrise Educational Session: Hyperpolarization & MR Applications
Sunrise Session

ORGANIZERS: Sebastian Kozerke, Ph.D. & Greig C. Scott, Ph.D.

Wednesday, 26 April 2017
Room 311  07:00 - 07:50 Moderators: James Bankson, Jessica Bastiaansen

Skill Level: Intermediate to Advanced

Slack Channel: #e_phys_eng
Session Number: SW09

This course is designed for physicists and engineers to provide an introduction to new or emerging MR methods and applications that are gaining interest. The session provides a description of the underlying physics principles, image acquisition and reconstruction methods, pitfalls and challenges associated with hyperpolarized MR imaging. The clinical potential of this new MR imaging method will be discussed.

Target Audience
Those with an interest in: 1) understanding principles of hyperpolarization, including the operation of commercially available dynamic nuclear polarization methods and alternative hyperpolarization methods, 2) understanding the optimial acquisition methods for rapid data acquisition of short-lived hyperpolarized nucleii, including image reconstruction methods, and 3) understanding the potential clinical applications and implementation of hyperpolarized MRI in a clinical setting.

Educational Objectives
Upon completion of this course, participants should be able to:
-Summarize and implement the optimum acquisition methods for rapid image acquisition for hyperpolarized nucleii with different chemical shift species;
-Create more efficacious experiments that utilize hyperpolaried MR for specific applications, with improved understanding of the limitations and pitfalls associated with hyperpolarized MRI; and
-Recognize the value of the added functional information and the clinical impact of metabolic imaging that is enabled by hyperpolarized MRI, and how this can be used in a clinical setting.

Hyperpolarization - Description, Overview & Method
Peder Larson
The goal of this educational session is to provide understanding of the basic principles of generating hyperpolarization and hyperpolarized MR imaging strategies, which have enabled novel in vivo imaging studies of metabolism, perfusion, pH, ventilation, redox state, and more.  This talk will cover hyperpolarization methods, including those used in clinical trials, and imaging strategies that efficiently use the non-recoverable magnetization.

Hyperpolarization - Clinical Potential & Relevance
Marie Schroeder


The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for
Continuing Medical Education to provide continuing medical education for physicians.