ISMRM 25th Annual Meeting & Exhibition • 22-27 April 2017 • Honolulu, HI, USA

Weekend Educational Course: MRI, MRS & Molecular Imaging to Diagnose Disease & Assess Treatment
Weekend Course

ORGANIZERS: Carolyn E. Mountford, D.Phil. & Bruce R. Rosen, M.D., Ph.D.

Sunday, 23 April 2017
Room 314  13:15 - 16:15 Moderators: In-Young Choi, Brenda Bartnik Olson

Skill Level: Basic to Intermediate

Slack Channel: #e_cancer_mol_mrs
Session Number: WE21

New methods for identifying precise pathways and disease types will be discussed. The combination of MRS and MRI with PET and RT will be introduced as will the concepts of specific targeting of disease based on molecular pathways.

Target Audience 
This course will be of interest to specialists in these areas as well as those wishing to learn about new developments.

Upon completion of this course, participants should be able to:
-Distinguish current capabilities of molecular imaging, MRS, MRI-PET and MRI-RT;
-Assess new directions for MR markers based on gene expression and cellular markers of disease; and
-Review MR hardware is required and why and new concepts in hardware.

Deregulation, Disease & Damage Recorded by MRS
Caroline Rae
This presentation will enable you to describe the current state of magnetic resonance spectroscopy in the detection of pathology; understand the drawbacks and problems associated with the use of MRS; and understand how MRS could be further improved to allow better diagnostic and research utility.

Imaging Applications of Ferumoxytol for MRI: Focusing on the Vasculature & Inflammation
Edward Neuwelt, Gerda Toth
Ferumoxytol is an ultrasmall, paramagnetic iron oxide and also a novel magnetic resonance imaging (MRI) contrast agent. With its unique features (long plasma half-life and delayed intracellular uptake) ferumoxytol may pay a crucial role in the MR imaging in the future. We have completed over 700 MRI studies with ferumoxytol in our institution, primarily for CNS imaging. In this presentation we go through the general properties and the specific opportunities of ferumoxytol-enhanced MRI in and outside the brain. 

Molecular Imaging of In Vivo Gene Expression & Intracellular Messengers
Zahi Adel Fayad
We cover the use MRI molecular imaging

Break & Meet the Teachers
MR-Guided Radiotherapy
Rob Tijssen
Online MRI guidance is the new disruptive technology for radiotherapy that will facilitate online and real-time adaptive treatments. An overview of the current hybrid MRI-guided treatment machines will be given. The MRI-Linac, which combines a 1.5T closed bore system with a modern 7MV linear accelerator will be described. Its clinical introduction is highlighted and the potential for future treatments and research is outlined.  

Imaging of Non-Proton Nuclei: Methodology & Applications in Clinical Research
Guillaume Madelin
In this presentation I will give an brief overview of X-nuclei MRI/MRS, of its challenges and potential clinical applications. I will mainly focus on 23Na MRI and 31P MRS/MRI as examples of potentially useful non-proton imaging methods that could give interesting new metabolic information in vivo in a non-invasive and quantitative manner.


The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for
Continuing Medical Education to provide continuing medical education for physicians.