Joint Annual Meeting ISMRM-ESMRMB • 16-21 June 2018 • Paris, France

Educational Course
Imaging Metabolism in the Developing Brain
Imaging Metabolism in the Developing Brain
Weekday Course

ORGANIZERS: Christopher Smyser, Pia Maly Sundgren

 
Tuesday, 19 June 2018
S01  08:15 - 10:15 Moderators:  Christopher Smyser

Skill Level: Intermediate
Session Number: Tu-02

Overview
This course focuses upon application of neuroimaging to study early-life brain metabolism. The session begins by discussing the current state of the field. Approaches and results from investigations employing MRI/S and other advanced neuroimaging techniques to study brain metabolism and related disorders will be discussed. The session will also include discussion of how neuroimaging can be used to study the effects of relevant clinical variables on brain development in populations of interest.

Target Audience
M.D.'s, Ph.D.'s and trainees who are interested in applying multimodality neuroimaging techniques, including MRS, to understand early-brain metabolism, related disorders, and relevant clinical variables impacting development in pediatric populations.

Educational Objectives
As a result of attending this course, participants should be able to:
-Describe the current state of knowledge and neuroimaging approaches for investigating early brain metabolism;
-Discuss results from recent investigations employing multimodality neuroimaging techniques to study pediatric brain metabolism and related disorders; and
-Apply neuroimaging techniques to better understand metabolism and the effects of relevant clinical variables in the developing brain.

 

 
08:15
 		   Glucose & the Developing Brain: What Do We Know?
Manu Goyal
08:45
 		   Effects of Nutrition on Brain Development
Manon Benders
09:15
 		   Using MRI/S to Study Metabolic Signatures of Early Brain Development & Disease
Noriko Aida, Moyoko Tomiyasu
In the developing brain, metabolites concentrations such as NAA, choline and myo-inositol show dynamic change. We can use 1H-MRS to measure such metabolite concentrations. It is important to know such signature for the precise evaluation of neonatal brain pathology, particularly in hypoxic-ischemic encephalopathy. 1H-MRS is also a powerful tool for the diagnosis and disease monitoring forpediatric neuro-metabolic diseases.

 
09:45
 		 Advanced Neuroimaging Techniques to Study Brain Metabolism in Pediatric Populations
Stefan Bluml
In this presentation, various methods that have been used or could potentially be used to study metabolism in the pediatric brain are presented. Beyond widely available proton (1H) MR spectroscopy, this includes phosphorus (31P) MRS, carbon 13 (13C) MRS methods as well as MR imaging approaches that measure the cerebral metabolic rate of oxygen.

 
10:15
 		   Adjournment & Meet the Teachers
Back
The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.