27th ISMRM Annual Meeting • 11-16 May 2019 • Montréal, QC, Canada

Educational Course
Functional & Dynamic MR Imaging of Peripheral Joints & Spine

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Functional & Dynamic MR Imaging of Peripheral Joints & Spine
Weekday Course

ORGANIZERS: Riccardo Lattanzi, Jung-Ah Choi, Miika Nieminen, Jan Fritz, Edwin Oei

Monday, 13 May 2019
Room 511BCEF  16:00 - 18:00 Moderators:  Jan Fritz, Valentina Mazzoli

Skill Level: Intermediate to Advanced

Session Number: M-09

Our joints facilitate movement, so why do we most often image them statically in a relaxed position? In this session, we will explore topics how MRI is used to assess joint mechanics during motion and under load, how prospective motion correction can be used to improve loaded images and potential clinical applications of functional and dynamic techniques.

Target Audience
Scientists and clinicians interested in biomechanics, functional imaging, and dynamic imaging.

Educational Objectives
As a result of attending this course, participants should be able to:
- Describe the MRI techniques used for dynamic imaging of joints;
- List the quantitative MRI measurements used to describe tissue changes under load; and
- Summarize which functional and dynamic MRI techniques have been used to study or diagnose clinical problems.


  Imaging Biomechanics of Whole Joints
David Wilson
  Prospective Motion Correction During Loading
Thomas Lange
Knee MRI with in situ loading is strongly hampered by subject motion. However, the resulting artifacts can be efficiently suppressed by prospective motion correction. The functional principle of prospective motion correction based on optical tracking is explained and its use for knee MRI with in situ loading is demonstrated. Challenges, limitations and pitfalls of the technique are addressed. Results of anatomical and relaxometric cartilage MRI with prospective motion correction are presented. Non-rigid body motion and tracking marker fixation are the main limitations for most orthopedic applications. The ease of implementation and the correction efficacy of prospective motion correction are sequence-dependent.

  Dynamic MRI of Joints: Technical Factors and Clinical Applications
Valentina Mazzoli
while static MRI is widely used clinically for the assessment of several joints, it often fails to provide information on their biomechanical and functional status. On the other hand, dynamic MRI allows to gather information on the normal and impaired musculoskeletal function during motion but is technically more challenging. This presentation will cover some of the technical factors needed to perform and analyze a dynamic MRI experiment of the joints, and will highlight some clinical and research applications where dynamic MRI can add useful information to conventional static imaging.

  Clinical Application: Loaded Imaging of the Spine & Peripheral Joints
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