27th ISMRM Annual Meeting • 11-16 May 2019 • Montréal, QC, Canada

Sunrise Session
Preclinical MRI: Methods & Applications: Future Challenges & Opportunities

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Preclinical MRI: Methods & Applications: Future Challenges & Opportunities
Sunrise Session

ORGANIZERS: Ed Wu, Elena Vinogradov, Lucio Frydman, Damian Tyler

Thursday, 16 May 2019
Room 513A-C  07:00 - 08:00 Moderators:  Damian Tyler, Ed Wu

Skill Level: Intermediate

Session Number: S-TH-03

Studies of animal models of human pathologies are critical for bridging research "from bench to bedside." Such studies are also essential for understanding the basic biological process and functions in humans. This course will first review the basic physical and biological aspects of in vivo animal MRI, then state-of-art neuroimaging, endogenous and exogenous contrasts, molecular and cellular imaging, and finally other animal imaging modalities including MR-PET and magnetic particle imaging (MPI).

Target Audience
Physicians, imaging scientists/engineers, medical physicists, technologists and other professionals with need for preclinical MR techniques to address transnational, clinical, and basic sciences questions.

Educational Objectives
As a result of attending this course, participants should be able to:
- Apply new MRI hardware and software to better assess small animal models of disease;
- Identify the strengths and limitations of preclinical MRI studies using specific MRI technologies, including MR-PET and MPI; and
- Design basic preclincial MRI experiments, including analyses and validation.


Physical Aspects
Claudia Oerther
This course demonstrates the possibilities of preclinical imaging systems in camparison to Human MRI systems. It shows the advantage of ultra high field  of certain applications, such as X-Nuclei Imaging (e.g. 23Na, 19F) Spectroscopy, Chemical Exchange Saturation Transfer (CEST) and Magnetization Transfer Imaging (MTC), fMRI, SWI and QSM and underlines the gradient and RF-coil technology used in preclinical systems. It shows the possibilities of magnetical particle imaging and preclinical PET/MR. 

  Biological Aspects
Video Permission Withheld
Michal Neeman
Preclinical studies and biological studies of small animals rely heavily on imaging for quantitative assessment of dynamic processes.

MRI provides an important tool for imaging multiple biological processes that are of central importance in fundamental and applied research

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The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.