27th ISMRM Annual Meeting • 11-16 May 2019 • Montréal, QC, Canada

Sunrise Session
Beginner's Guide to Perfusion MRI

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Beginner's Guide to Perfusion MRI
Sunrise Session

ORGANIZERS: Fernando Calamante, Hanzhang Lu

 
Thursday, 16 May 2019
Room 510A-D  07:00 - 08:00 Moderators:  Sophie Schmid, Luis Hernandez-Garcia

Skill Level: Basic

Session Number: S-TH-04

Overview
The main methods for measuring cerebral perfusion will be introduced in two presentations at an introductory level. In the first presentation, the acquisition and post-processing of arterial spin labeling MRI will be explained. The second lecture will provide an introduction to contrast agent-based methods for measuring perfusion and permeability (dynamic susceptibility contrast [DSC] and dynamic contrast enhanced [DCE] MRI).

Target Audience
This course is aimed at research scientists and clinicians who would like to be exposed to various MR perfusion approaches. It is expected to provide attendees with a basic understanding of fundamental as well as practical aspects of these techniques, benefiting their clinical and/or research programs.

Educational Objectives
As a result of attending this course, participants should be able to:
-Relate the methods used to acquire and analyze dynamic susceptibility contrast (DSC) and dynamic contrast enhanced (DCE) MRI to the relevant physiological information;
-Demonstrate an understanding of arterial spin labeling (ASL) and identify its strengths and weaknesses; and
-Compare DSC, DCE, and ASL and evaluate which method is appropriate for a given application.

 

 
07:00
 
  Perfusion: ASL Basics & Analysis
Yang Li
This educational talk covers the data acquisition of arterial spin labeling (ASL) technique and steps to obtain quantified cerebral blood flow (CBF) map. ASL data acquisition is usually composed of three components: labeling module to tag blood water in major feeding arteries, post-labeling delay module to allow tagged blood to reach tissue, and readout module to acquire images. ASL data processing involves motion correction and perfusion quantification using general kinetic model. In addition, common issues met in practice and examples of clinical application of ASL are briefly discussed. 

 
07:30
 
  Perfusion: DSC & DCE Basics & Analysis
James Ewing
This syllabus outlines the teaching objectives of the Sunrise Session "DSC and DCE Basics and Analysis." This is essentially a large-scale overview of Dynamic MRI studies, intended to provide directions for further study in a general audience.

 
08:00
 
  Adjournment
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